MBtest 1 IN

The focal distance of the immersion objective is:
1. 1-2 m
2. 1,5-3
3. 5-10
4. 0,5
5. 0,001-0,01
!!! (2)
The immersion objective is marked by:
1. Red stripe
2. White stripe
3. Black stripe
4. Yellow stripe
5. Is not marked
!!! (3)
Dark field microscopy is based on the phenomenon of:
1. Changing the amplitude of light passing through the transparent
objects
2. Diffraction of light at strong lateral illumination
3. Fluorescence
4. Immersion of objective into immersion oil
5. Irradiation of the studying object with a flow of electrons
!!! (2)
Which of the following microorganisms belong to eukaryotes:
1. Bacteria
2. Fungi
3. Viruses
4. Mycoplasma
5. Protozoa
!!! (2,5)
Which of the following microorganisms belong to prokaryotes:
1. Bacteria
2. Fungi
3. Protozoa
4. Mycoplasma
5. Viruses
!!! (1,4)
What technique is used for studying the living microorganisms (the
motility of microorganisms):
1. Gram's staining
2. Ziehl-Neelsen's staining
3. "Wet-mount" and "hanging drop" techniques
4. Staining by Ozeshko
5. Staining by Burry-Gins
!!! (3)
Gram-positive microorganisms are:
1.
Red colour
2.
Violet colour
3.
Green colour
4.
Yellow colour
5.
Brown colour
!!! (2)
Gram-negative microorganisms are:

1.
Red colour
2.
Violet colour
3.
Green colour
4.
Yellow colour
5.
Brown colour
!!! (1)
The differentiation of Gram positive and Gram-negative bacteria by Gram's
staining happens at the stage of:
1. Treating with gentian violet
2. Treating with Lugol's (Iodine) solution
3. Treating with alcohol
4. Washing with water
5. Treating with aqueous fuchsin solution (Pfeiffer's fuchsine)
!!! (3)
The method of staining by Ziehl-Neelsen allows to differentiate:
1.Gram-positive and Gram-negative bacteria
2.Acid fast bacteria and non-acid fast bacteria
3.Mobile and immobile bacteria
4.Capsule formed and capsule unformed bacteria
5.Bacteria, which have inclusions
!!! (2)
What organelles are absent in the cell of prokaryotes:
1. Mitochondria
2. Cell wall
3. Ribosomes
4. Nucleus
5. Golgi complex
!!! (1,4,5)
Adhesive function of bacteria is carried out by:
1.
Cell wall
2.
Capsule
3.
Flagella
4.
Pili of common type
5.
Sex pili
!!! (2,4)
Capsules of bacteria are revealed at staining by the method:
1. Gram's method
2. Ziehl-Neelsen's method
3. Ozeshko's method
4. Burry-Gins' method
5. Neisser's method
!!! (4)
Spores of bacteria are revealed at staining by the method:
1. Gram's method
2. Burry-Gins' method
3. Ozeshko's method
4. Neisser's method
5. Romanowsky-Giemsa's method
!!! (3)
The cell wall is absent in the microorganisms:
1. Bacteria
2. Mycoplasma
3. Chlamidia
4. Rickettsia
5. Spirochetes
!!! (2)
Endoflagella of spirochetes are:
1. Three or four endoflagella attached on both ends of the cell
2. Consist of a protein flagellin
3. Are in the space between the cell wall and the outer membrane layer
4. Provide different types of spirochetes' movement (forward and
backward, rotary (rotation around the long axis), flexuous (flexion of
the body), pendulous (pendulum-like)
5. All the listed above answers
!!! (5)
Bacteria of Prokaryotae kingdom
are divided into 35 groups in the
Bergey's Manual of Determinative
bacteriology on the basis of:
1.
Morphology
2.
Gram reaction
3.
Oxygen requirement
4.
Spore formation
5.
Metabolic products.
!!! (1,2,3,4,5)
The sterilization of the nutrient media is carried out with the help of:
1. Flaming
2. Boiling
3. Dry heat
4. Autoclaving (sterilization by steam under pressure)
5. Ultra violet radiation
!!! (4)
Laboratory glass utensil is sterilized by:
1. Dry heat
2. Boiling
3. Tyndalization
4. Pasteurization
5. All the above-mentioned methods
!!! (1)
What culture media are classified
as the basic ones:
1. Nutrient broth (meat-peptone broth- MPB), nutrient agar (MPA)
2. Blood agar and serum agar
3. Alkaline nutrient broth and nutrient agar
4. The nutrient media with carbohydrates (sugar media)
5. Endo' medium, MacConkey' medium
!!! (1)
What media are classified as complex ones:
1. Nutrient broth (MPB), nutrient agar (MPA)
3. Alkaline nutrient broth and alkaline nutrient agar
4. Hiss' media
5. Endo' medium, MacConkey' medium
!!! (2)
?

:
1. (M),
(MA)
2.
3.
, -
4.
( )
5. ,
medium
!!! (3)
?
:
1.
2.
3.
4.
5.

of
!!! (4)
?

cultivating
:
1. , ,
2. - ,
thioglycollate
("
medium"),
"), medium)
( )
3. -
4. (),
5.

!!! (2,4)
?

bacteria is

:
of:
1.
2.
3.
4.
5.
What media are classified as

selective ones:
1. Nutrient broth (MPB), nutrient
agar (MPA)
3. Alkaline nutrient broth and
alkaline nutrient agar, yolk-salt
agar
4. The nutrient media with
carbohydrates (sugar media)
5. Endo' medium, MacConkey'
1.
2.
3.
4.
5.
Hiss' media belong to:

Basic media
Complex media
Selective media
Differential media
Nutrient media for cultivating
anaerobic microorganisms
What media is used for

anaerobic microorganisms:
1. Hiss' media, Endo' medium,
MacConkey' medium
2. Iron-sulfite agar,
broth ("sterility testing
blood-sugar agar (Zeissler'
3. Yolk-salt agar
4. Shaedler's agar (broth),
Robertson' s medium
5. Alkaline nutrient broth and
alkaline nutrient agar
The differentiation of
done on Endo' medium, MacConkey'
medium due to the fermentation
1.
2.
3.
4.
5.
Glucose
Lactose
Maltose
Mannitol
Proteins
!!! (2)
?
-
:
1. E. coli
2. Clostridium spp.
3. Streptococcus spp.
4. Staphylococcus spp.
5.
!!! (4)
?

:
facilitated
1.
material
2.
20 80C
material at
3.
material
4.

nutrient
5.
1.
2.
3.
4.
5.
On yolk-salt agar can grow:

E. coli
Clostridium spp.
Streptococcus spp.
Staphylococcus spp.
All listed above
Isolation of pure culture of

sporogenous bacteria is
by:
1. Treating of the testing
with an acid
2. Heating of the testing
80C for 20 minutes
3. Treating of the testing
with glucose
4. Additional aeration of
media
5. All the enumerated conditions
!!! (2)
?

syringes
:
1.
2.
3.
4.
5.
!!! (4)
?

of
:
1. 3
2. 37C
24
24
3.
the

4.
the

autoclave
The disposable plastic

are sterilized by:
1. Ultra-violet radiation
2. Boiling
3. Dry heat
4. Gamma-radiation
5. Autoclaving
The control of the sterility

nutrient media is carried out by:
1. Placing them for 3 days into a
refrigerator
2. Their incubation at 37C for
hours
3. Measurement of temperature in
sterilization chamber
4. Placing fusible materials into
sterilization chamber of an
5.
!!! (2)
?

the
:
1. 1
2. 1
3. 20-30
4. 20
5. 2-3
5. Realization of all the listed

actions
The period of generation of

most of bacteria under optimum
conditions is:
1. 1 day
2. 1 minute
3. 20-30 minutes
4. 20 seconds
5. 2-3 days
!!! (3)
?

:
studied
1. ,
2. -
3.
4.
5.
!!! (3)
?

help of
:
1. ,
,
2.
3. -
4.
5. (M)
!!! (1)
?

testifies

:
sugarolytic
1.
( )
proteolytic
2.
oxidative3.
4.
The carbohydrates-splitting
properties of bacteria are
with the help of:
1. Nutrient broth, nutrient agar
2. Yolk-salt agar
3. Hiss' media
4. Shaedler' agar
5. Alkaline nutrient agar
The proteolytic properties of

bacteria are studied with the
nutrient media:
1. MPB with the indicator papers,
peptone water, gelatin column
2. Hiss' media
3. Yolk-salt agar
4. Alkaline nutrient agar
5. Nutrient agar (MPA)
The formation of indol

the enzymatic activity of:
1.
The presence of
(carbohydrates-splitting) enzymes
of bacteria
2.
The presence of
enzymes of bacteria
3.
The presence of
reductive enzymes of bacteria
4. The presence of lipolytic
enzymes of bacteria
5. The presence of beta-
lactamases
5. beta-
!!! (2)
?

of
:
1.
2.
3.
4.
enzymes
5. beta-
lactamases
!!! (3)
?
<>
term
( ):
1.
,

2.
of

3.
ecosystems
4.
ecosystems
5.
!!! (2)
?

term
<>:
1.
,

2.
of

3.
ecosystems
4.
ecosystems
5.
!!! (1)
?
The formation of hydrogen

sulphide testifies the presence
enzymes in bacteria:
1. The presence of sugarolytic
enzymes of bacteria
2. The presence of oxidativereductive enzymes of bacteria
3. The presence of proteolytic
enzymes of bacteria
4. The presence of lipolytic
of bacteria
5. The presence of beta-
To give the definition of the

"biotope" (ecological area):
1. The totality of members of one
species living in a limited site
of the biosphere
2. A territorially limited site
the biosphere with homogeneous
conditions of life
3. The totality of soil
4. The totality of water
5. The totality of air ecosystems

"population":
1. The totality of members of one
of the biosphere
conditions of life
3. The totality of soil
4. The totality of water
5. The totality of air ecosystems

term
<>:
1.
one
,

2.
of

3.,
ecological

4.

5.
ecological
!!! (4)
?

per
1 :
as:
1.
-
2.
-
3.
-
4.

5.
-
!!! (3)
?
,
which

bacteria
, :
1.
-
2.
-
3.
-
4.

5.
-
!!! (1)
?
-

:
1.

genus
Streptococcus
2.
Escherichia coli
3.
Citrobacter spp.
4.

genus

"microbiocenosis":
1. The totality of members of
of the biosphere
conditions of life
3. The system including
area and its microbial totality
4. The sum of populations of
microorganisms living in certain
ecological area
5. Total sum of all the
systems
Quantity of coliform bacteria

1 liter of water is designated
1.
2.
3.
4.
5.
Coliform bacteria - titer

Cl. perfringens - titer
Coliform bacteria - index
Total microbial amount
Cl. perfringens - index
Minimal volume of water, in

one bacterium of coliform
group can be revealed, is named
1.
2.
3.
Coliform bacteria - index
4.
5.
Cl. perfringens - index
Sanitary - indicative
microorganisms of air of hospital
rooms are:
1.
Hemolytic bacteria of
Streptococcus
2.
Escherichia coli
3.
Citrobacter spp.
4.
Hemolytic bacteria of
Staphylococcus
5.
Sarcina spp.
!!! (1,4)
?
Staphylococcus
5.
Sarcina spp.
-
:
1.
2.
3.

4.

5.

The detection of coliform

bacteria-index and coliform
bacteria-titer of water can be
carried out by methods:
1.
Sedimentation
2.
Aspiration
3.
Membrane filters method
4.
Gram' method
5.
Drigalskiy' method
!!! (3)
?

-
air
:
1.
2.
3.
4.
5.
!!! (4)
?
-
bacteriological
:
1.

2.
-
3.
-
4.

bacteria
5.

bacteria
!!! (1,2,3,5)
?

at
:
1.
Bifidobacterium
Bifidobacterium spp.
2. 5. coli
, 1011
3. 5. coli
coli
4.
Staphylococcus spp.
5. , ,
example,
Determination of quantity of
sanitary - indicative bacteria of
is carried out on nutrient media:
1. P
2. Endo' medium
3. Heikmann' medium
4. Blood P
5. Shaedler' medium
At the sanitaryexamination of soil are defined:

1.
2.
3.
4.
Titer of halophilic
5.
Titer termophilic
What changes of structure of

normal intestine microflora occur
dysbios:
1. The decrease of
spp. quantity(amount)
2. The increase of 5. coli
quantity(amount) more than 1011
bacteria per gram of faeces
3. Occurrence of hemolytic 5.
4. Occurrence of hemolytic
Staphylococcus spp.
5. The increase of quantity of
opportunistic pathogens, for
Proteus, Candida ..
!!! (1,2,3,4,5)
?

:
functions:
1.

2. ,
toxins,

Enterobacteriaceae
3. Ca2+,
processes
D
intestine
4. -
electrolyte

5. , ,
proteins,
!!! (1,2,3,5)
?
,
the
,
of

damaged

membrane

1.
2.
3.
4.
5.
!!! (2)
?

:
1.

peptidoglycan
2.

of
3.
4.
and
5.
genera Proteus, Candida and etc.

The normal microflora of the
human body carries out the
1.
Antagonistic function for
pathogenic microorganisms
2. Inhibitory function for
produced by microorganisms of
Enterobacteriaceae
3. Improvement of resorbtion
of ions Ca, vitamin D in
4. Regulation of fluid-andbalance of the human body
5. Production of aminoacids,
vitamins
To point out the term meaning

totality of methods of inhibition
growth and multiplication of
microorganisms on intact or
surfaces of skin and mucous
of a body:
1.
Disinfection
2.
Antiseptisis
3.
Aseptisis
4.
Sterilization
5.
Disinsection
To point out the mechanism of

antimicrobial activity of
penicillins:
1. Inhibition of
synthesis of the cell wall
2. Increase of permeability
the cytoplasmatic membrane
3. Inhibition of protein
synthesis in bacteria
4. Oxidation of metabolites
enzymes of bacteria
5. Damage of the genetic
apparatus of bacteria
!!! (1)
?

:
1.

peptidoglycan
2.

permeability of
3.
4.
and
5.

tetracyclines:
1. Inhibition of
2. Increase of
enzymes of bacteria
!!! (3)
?

spectrum
:
1.
- negative

2.
3.
4.
5.
!!! (1,2,4,5)
?

:
1.

peptidoglycan
2.

permeability of
3.
4.
and
5.
Point out antimicrobial

of chloramphenicol:
1. Gram-positive and Grambacteria
2. Spirochaetes
3. Actinomyces
4. Chlamydiae
5. Rickettsia

antimicrobial activity of polyene
antibiotics:
1. Inhibition of
2. Increase of
enzymes of bacteria
!!! (2)
?

:
rifamycin:

1.

2.

3.
synthesis
4. - RNA

5.
!!! (4)
?

:
1.

into
2.

3.

for
4.
(efflux)
drugs
5.
-
of
1. Inhibition of peptidoglycan
2. Increase of permeability of
in bacteria
4. Inhibition of DNA-dependent
polymerase and as the result the
inhibition of all forms of
bacterial RNA synthesis
5. Oxidation of metabolites and
enzymes of bacteria
Point out the mechanisms of

formation of resistance to
antimicrobial drugs in
microorganisms:
1. Decrease of drug penetration
the bacterial cells
2. Metabolic inactivity of
antimicrobial medicines
3. Change of the target structure
antimicrobial medicines
4. Acceleration of removal of
from the bacterial cell (efflux)
5. Change of metabolic activity
cell-targets
!!! (1,2,3,4,5)
?
,
are

diseases
:
1.
2.

3.
4.
5.
!!! (3,4,5)
?
,
,
at
, :
to
1.
2.
3.
Point out the drugs, which

used for
treatment of the
caused by pathogenic Mycoplasmas:

1. Penicillins
2. Polyene antibiotics
3. Cephalosporins
4. Tetracyclines
5. Quinolones
Name the form of symbiosis,

which one population, doing harm
other population, gets profit:
1. Commensalism
2. Antagonism
4.
5.
3. Parasitism
4. Mutualism
5. Neutralism
!!! (3)
?
,
at

live :
1.
2.
3.
4.
5.
!!! (2)
?

is
:
1.
2.
3.
4.
5.
(NK)
!!! (2)
?
Name the form of symbiosis,

which one population suppresses
activity
1.
2.
3.
4.
5.
of the other population:

Commensalism
Antagonism
Parasitism
Mutualism
Neutralism
Innate cell-mediated immunity

provided by:
1.
Lysozyme
2.
Phagocytes
3.
Bacteriophages
4.
Complement
5.
All listed above

:
1.
2.
3.
4.
5.

!!! (5)
?
Innate humoral immunity is

provided by:
1.
Lysozyme
2.
Complement
3.
Interferons
4.
Lactoferrin
5.
All listed above

,
:
1.

2.
, ,
,
3.
- B-
4.

5.
(NK)
!!! (3)
?
The factors of innate immunity

are all mentioned below,
except:
1.
Skin and mucous covers
2.
Lysozyme, complement,
interferons, properdin
3.
- and B -lymphocytes
4.
Normal microflora of the
human organism
5.
Natural killer cells (NK)
and phagocytes
,
which

:
diseases:
1.

Name the kind of immunity

is formed after convalescence
(recovery) from infectious
1.
Artificial active
2.

3.

4.

5.

!!! (2)
?
2.
3.
4.
5.

, :
1.
2.
O
3.
K
4.
Rh
5.
Vi
!!! (4)
?
Bacterial cells can have the

following antigens, except:
1.
2.
O
3.
K
4.
Rh
5.
Vi

, ,

():
1.
IgG
2.
IgM
3.
sIgA ( IgA)
4.
Ig
5.
IgD
!!! (3)
?
Local immunity of the mucous

membrane of the mouth, intestine,
respiratory tract and
genitourinary system is provided
by immunoglobulins class(es):
1.
IgG
2.
IgM
3.
sIgA (secretory IgA)
4.
Ig
5.
IgD
()
"cytotropic"
,

:
1.
IgG
2.
IgM
3.
IgA
4.
Ig
5.
IgD
!!! (4)
?
()
()
1.

2.

3.

but
,

4.

molecules
5.

Natural active
Artificial passive
Natural passive
All listed above
Name class(es) of
immunoglobulins, which is(are)
responsible for the anaphylactic
type of hypersensitivity:
1.
IgG
2.
IgM
3.
IgA
4.
Ig
5.
IgD
To select the best

characteristic(s) of haptens:
1.They are immunogenic and react
with antibodies in a specific way
2.They are immunogenic and do not
react with antibodies
3.They are incapable of inducing
antibodies formation themselves,
can react with antibodies in a
specific way
4.They are not immunogenic and do
not react with antibodies
5.They are large protein

!!! (3)
?
()
secretory
(sIgA):
(sIgA):
1.
2.
3.
4.

bacteria

mucous
5.
!!! (1,2,4)
?
,
:
1.
2.
3.
4.
5.

To name property(ies) of
immunoglobulins of A class
1.Contain a secretory component.
2.It is dimer
3.It is transported through the
placenta
4.Inhibit the adherence of
and viruses to the surface of
membrane cells
5. All enumerated above
To name the kind of antigens,
which takes part in agglutination
reaction:
1.
Soluble
2.
Particulate
3.
Autoantigens
4.
Viral
5.
All listed above
!!! (2)
?

are

of
:
1.
2.
3.
4.
5.

!!! (5)
?
,
which

test
:
1.
2.
3.
4.
5.
!!! (3)
?

():
1.
The agglutination reactions

used in microbiological methods
diagnostics:
1.
Bacteriological
2.
Serological
3.
Biological
4.
Rickettsiological
5.
All enumerated above
To name the type of serum,

is used in complement fixation
(CFT):
1.
2.
3.
4.
5.
Antiimmunoglobulin serum
Antitoxic serum
Haemolytic serum
Agglutinating serum
All listed above
Erytrocytic diagnosticums are

used in reaction(s):
1.
Agglutination
2.
3.
4. ()
5.
!!! (4)
?
() ,
antigens,
() ()
precipitation
:
1.
2.
3.
4.

organism
5.

!!! (1)
?
()
:
1.
test
( )
2.
gel
3.
gel
4.
5.
!!! (5)
?

reactions
:
1.
2.
3.
4.

5.
!!! (3)
?
1.
2.
3.
4.
5.
2.
Precipitation
3.
Complement fixation test
4.
Passive (indirect)
haemagglutination test
5.
Immune haemolysis
To name kind(s) of the

which take(s) part in
reaction:
1.
Soluble
2.
Particulate
3.
Erythrocytes
4.
Cells of the human
5.
All listed above
To point out variant(s) of

precipitation reaction:
1.
Ring thermoprecipitin
(by Ascoli)
2.
Double immunodiffusion in
3.
Single immunodiffusion in
4.
5.
Immunoelectrophoresis
All enumerated above
Schick's and Dick's

concern
1.
2.
3.
4.
5.
reactions of:
Agglutination
Precipitation
Neutralization
Immunofluorescent test
Complement takes part in

reaction:
1.
Agglutination
2.
Precipitation
3.
Neutralization
4.
5.
!!! (4)
?

:
Antitoxic sera are used in

reaction:
1.
2.
3.

4.
5.
()
!!! (1)
?
1.
Neutralization
2.
Agglutination
3.
4.
5.
Passive (indirect)
haemagglutination test
() ,

reactions
:
1.-
2.
3. (
)
4.
5.
To point out the kind(s) of

reactions, which concern
!!! (1,2,3,5)
?

:
1.

2.

3.

4.
5.

immunodiffusion
!!! (1,4,5)
?

in
()
:
1.
2.
3.
4.
5.
(- , )
!!! (1,2,3,4)
?

of
() ()
:
assay
1.

2.
-
3.

4.
5.

with labeled antibodies:

1. Enzyme-linked immunosorbent
assay
2. Radioimmunoassay
3. Immunofluorescent test (Coons
method)
4. Complement fixation test
5. Immunoblotting
Antiglobulin sera to human

immunoglobulins are used:
1.
For diagnostics
2.
For therapy
3.
For prophylaxis
4.
In ELISA
5.
In Manchini
Immunofluorescent test is used

the following method(s) of
diagnostics:
1. Serological
2. Microscopic
3. Biological
4. Bacterialogical
5. Allergic (skin allergic tests,
hypersensivity tests)
Labeled antiglobulin sera are

used in the following method(s)
diagnostics:
1.Enzyme-linked immunosorbent
2.Radioimmunoassay
3.Precipitation reactions
4.Immunoblotting
5.Indirect immunofluorescent test
!!! (1,2,4,5)
?
:
1.

2.

3.

4.

5.

!!! (2,4)
?

:
1.
2.
3.
test
()
4.
5.
!!! (3)
?
() ()
is(are)
()
:
1.
2.
3.
4.
5.
!!! (4)
?
:
1. (
)
2. ()
3.
4.
5.
1.
2.
3.
4.
5.
Haemolytic system consists of:

Testing serum
Sheep erythrocytes
Normal serum
Haemolytic serum
All listed above
According to the mechanism

Manchini's reaction is:
1.Agglutination reaction
2.Ring thermoprecipitin test
3.Gel diffusion precipitation
4.Complement fixation test
5.All enumerated above
The followig reaction(s)

used for estimation of the immune
status:
1.
Whright reaction
2.
3.
Manchini reaction
4.
Ascoli reaction
5.
All listed above.
To point out the types of

vaccines:
1.Alive (the avirulent mytants or
attenuated) vaccines
2.Killed (inactivated) vaccines
3.Component vaccines
4.Recombinant vaccines
5.Toxoids (anatoxins)
!!! (1,2,3,4,5)
?

:
purpose:
1.
2.
( )
3.
illnesses
4.
5.
!!! (5)
?
In medical practice immune

globulins are used with the
1.Specific therapy
2.Emergency prevention (emergency
immunoprophylaxis)
3.Diagnostics of bacterial
4.Diagnostics of virus infections
5.All listed above

formed
:
1.

2.

3.

4.

5.
()
What type of immunity is

as the result of immunization of
vaccines:
1.
Natural active
2.
Natural passive
3.
Artificial active
4.
Artificial passive
5.
Innate (natural)
!!! (3)
?

:
1.
2.
3.

4.

5.

!!! (1,2,3)
?

:
1.
2.
3.
4.
5.

!!! (4)
?

formed

sera
:
1.

2.

3.

4.

5.
()
!!! (4)
?

are
:
1.
2.
3. -
assay
4.
5.
!!! (5)
?

Diagnosticums are used in

reaction(s):
1.
Agglutination
2.
Precipitation
3.
4.
Ascoli precipitation
5.
1.
2.
3.
4.
5.
The diagnostic sera can be:

Agglutination sera
Precipitation sera
Antitoxic sera
Haemolytic sera
All listed above
What type of immunity is

as the result of immunization of
and immune globulins:
1.
Natural active
2.
Natural passive
3.
Artificial active
4.
Artificial passive
5.
Innate (natural)
Fluorescent antiglobulin sera

used in reaction(s):
1.Precipitation
2.Direct immunofluorescent test
4.Passive haemagglutination
5.Indirect immunofluorescent test
Tuberculin is used in
reaction:
:
1.
2.
3.
4. ( )
5.
!!! (4)
?

prokaryotes
:
1.

2.

organization
nutrient
3.

alive
(, )
4.

in

5.

-
!!! (1,4,5)
?

:
1.

staning
2.

3.

(for
(,
)
4.

5.

of

!!! (2,3,4)
?
:
1.
virion
2.
3.
4.
5. ,
which is
host
1.Agglutination
2.Precipitation
3.Manchini
4.ontoux (tuberculin skin test)
5.Dick
The viruses differ from

and eukaryotes by following
properties:
1. Presence of only one type of
nucleic acid
2. Presence of cellular
3. Viruses are cultivated on
media (for example, P)
4. Viruses are cultivated into
cells
5. Viral genome can be integrated
genome of a host cell
Viruses are classified into

families on the basis of:
1.
Distinction of Gram
2.
3.
Type of nucleic acid

Morphological features
example, presence or absence of

envelope)
4.
Size of a virus
5.
Aerobic or anaerobic type
biological oxidation
Capsid is:
1.Obligatory structure of a
2.Polypeptide coat of a virion
3.Single envelope of envelouped
virions
4.Contains antigens of a virion
5.The structure of a virion,
formed from the membrane of a
cell
!!! (1,2,4)
?
:
1.
-
2.
-
3.

4.
5.
!!! (1,2,3,4,5)
?
:
possible
1.
MA
2.

3.

4.

5.

!!! (2,3,5)
?

of
:
1.
2.
3.
4.

5.

!!! (1,2,4)
?
() ()
:
1.
-
2.

3.
-
4.

5.

!!! (2,4)
?

of
:
1.

2.-
3.
electronic
4.
5.
!!! (1,2,3)
?

:
Viruses can have the enzymes:

DNA-polymerase
RNA- polymerase
Reverse transcriptase
Neuraminidase
Lysozyme
1.
2.
3.
4.
5.
Reproduction of viruses is
in:
1.
2.
3.
4.
5.
MPA
Chick embryo
Laboratory animals
Schaedler nutrient medium
Cell cultures
To name structural components
virion:
1.
2.
3.
4.
5.
Capsid
Envelope
Ribosomes
DNA or RNA
All listed above
To name the basic method(s) of

study of viruses morphology:
1. Dark-field microscopy
2. Electronic microscopy
3. Phase-contrast microscopy
4. Scanning electronic microscopy
5. All enumerated above
To name methods of detection

viruses sizes:
1.Filtering through filters with
known diameter of apertures
2.High-speed centrifugation
3.Photographing with the
microscope
4.CR test
5.All listed above
To name the basic properties
of
1.
viral
2.

3.
synthesis
4.
immunity
5.
!!! (5)
?

:
1.
Ig G
2.
Ig M
3.
Ig A
4.
Ig E
5.
!!! (1,2,3)
?

nonspecific

:
1.Ig G
2.
the
3.
4.Ig M
5.
!!! (3,5)
?

laboratory
:
1.
2.
antibodies
3.
of

viruses
4.
5.
!!! (1,2,3)
?

interferons:
1.They provoke degradation of
messenger RNA (mRNA)
2.Interferons are nonspecific in
relation to viruses
3.They block viral proteins
4.They are factors of innate
5.All listed above
To list specific humoral

mechanisms of neutralization of
viruses:
1.
Ig G
2.
Ig M
3.
Ig A
4.
Ig E
5.
Interferons
To list mechanisms of
antiviral protection:
1.Ig G
2.Phagocytosis of infected cells
3.Absence of cell receptors to
viruses
4.Ig M
5.Interferons
To name principles of
diagnostics of viral infections:
1.Revealing of specific viral
antigens
2.Revealing of specific
3.Detection of specific sequences
viral nucleic acids
4.Revealing of the factors of
pathogenicity
5.All listed above
To list components for the
()

the

1.
2.
3.
4.
5.
reaction of inhibition of
haemagglutination (RIH) with
purpose of identification of
haemagglutinating virus
1.Testing virus
2.Specific immune serum
3.Erythrocyte diagnosticum
4.Erythrocytes
5.Haemolytic serum
!!! (1,2,4)
?

()
:
the
1.
antibodies
2.
3.
4.
5.

reaction of inhibition of
haemagglutination (RIH) with
purpose of detection of
to a virus:
1.Haemolytic serum
2.Testing serum
3.Erythrocytes
4.Specific virus diagnosticum
5.Erythrocyte diagnosticum
!!! (2,3,4)
?

:
purpose
1.
2.
3.
4.
5.
!!! (1,2,4)
?

of
:
1.
2.
3. -
tests
4.
differentiation
5. (
culture)

)
!!! (1,2,5)
?

reaction of metabolic inhibition
under colour probe with the
of identification of a virus:
1.Cell culture in growth medium
2.Diagnostic immune serum
3.Haemolytic serum
4.Testing virus
5.Working dose of complement
To name the purposes of using

bacteriophages in medicine:
1.Specific treatment
2.Emergency prevention
3.Procedure of skin-allergic
4.Detection of phagocytosis
efficiency
5.Diagnostics (phage
and phage typing of bacterial

,
carrying

:
information:
1.
2.
3.
4.
5.
!!! (2,3)
?

of
:
1.
of

2.
factors

3.
autonomic
(
themselves
)
4.

5.

formation of
,
of
, F-
..
!!! (2,3,4,5)
?

an
:
1.
2.
3.
4.
5.
!!! (4)
?

the
()

?
1.
Lag
after

To name the structures of

prokaryotic cells which are
out the function of storage and
transfer of hereditary
1.
2.
3.
4.
5.
Mesosomes
Plasmids
Nucleoid
Capsule
Ribosomes
To list the basic properties

plasmids:
1.They are the chrosomal factors
heredity
2.They are the extrachrosomal
of heredity
3.They are able to fulfil
replication (can replicate
independently of the chromosome)
4.They can be transfered
independently of the chromosome
5.They can code resistance of
bacteria to antibiotics,
enzymes pathogenicity, formation
F-pili etc.
To point out another name for

antigenic determinant is:
1.
Immunogen
2.
Paratope
3.
Carrier
4.
Epitope
5.
Antigen
Which of the following

characteristics best describes
anamnestic (secondary) immune
response in comparison with the
primary immune response?
1.
Lag period is longer
antigenic stimulus
2.

3.
IgM
predominates
4.

required
immune
5.

!!! (2)
?

an
- 1
?
1.
- C1q, C1r
C1s
2.
classical
-
esterase
3.
peptidase
4.
5.
4
!!! (2)
?

(FTA-ABS),
test,

,
slide
, :
1.Treponema pallidum
organisms
2.
antibody
Treponema pallidum
3.
antibody

4.
5.
!!! (1)
?

tract
, :
1.
sIgA
2.

2.
3.
More antibody is produced

IgM production
4.
More immunogen is
5.
It characterizes the
response to carbohydrate antigens
Which of the following is NOT

accurate description of the
complement component C1?
1.
It is composed of five
polypeptide chains - one C1q, two
C1r and two C1s
2. It is part of both the
and alternative pathways
3. The activated form is an
4.The activated form is a
5.Its natural substrate is C4
In the fluorescent treponemal

antibody absorbtion (FTA-ABS)
used to diagnose syphilis, the
patient's serum is added to a
containing:
1.
Treponema pallidum
2.
Fluorescein-tagget
to Treponema pallidum
3.
Fluorescein-tagget
to human immune globulins
4.
Fluorescein isocyanate
5.
Complement and sheep red
blood cells
Immunity in the respiratory
depends on all of the following
EXCEPT:
1.
Locally produced sIgA
2.
Cell-mediated immunity
associated with bronchus-
associated
3.
4.

5.
IgE
epithelium
lymphoid tissue
3.
Lactoferrins
4.
Mucus and ciliated
5.
Locally produced IgE
!!! (2)
?

a

?
cells
1.
2.
3.
4.
!!! (3)
?

to
Enterobacteriaceae
1.
Escherichia
2.
Shigella
3.
Salmonella
4.
Vibrio
5.
Yersinia
!!! (1,2,3,5)
?

Enterobacteriaceae:
1. -, , ,
nonmotile

2. -,, ,
nonmotile

3. -,, ,
nonmotile

4. -,,
motile
,
5.
-,
shaped,
,
!!! (4)
?

which

Which of the following is NOT

component of innate immunity?
1.Desquamation of epithelial
2.Lysozyme
3.Antibodies
4.Complement
Which genera of bacteria belong

Enterobacteriaceae family:
1.
Escherichia
2.
Shigella
3.
Salmonella
4.
Vibrio
5.
Yersinia
To name the morphological and

tinctorial properties of
1.
Gram positive nonsporing,
noncapsulated, motile or
rods
2.
Gram negative nonsporing,
rods
3.
Gram positive sporing,
rods
4.
noncapsulated or capsulated,
or nonmotile rods
5.
Gram negative commamotile rods
To name the nutrient media,
are acceptable for cultivation
and

Enterobacteriaceae:
1.
- (),
- (A)
2.
A
3.
- ()
4.
- ,
medium
5.
,
(MacConkey' medium)
!!! (5)
?

( Shigella)
1.
-,
,
,
2.
-,
,
,
3.
-,
, ,

4.
-,
, ,
,
5.
-,
, ,

!!! (2)
?
Shigella sonnei
:
1.

2.

3.

4.
3-5
5.
3-5
!!! (4)
?

Shigella:
1.
Sh.dysenteriae
2.
Sh.boydii
3.
Sh.flexneri
4.
Sh.sonnei
5.

!!! (4)
?

:
presence
differentiation of bacteria of
1. PB, PA
2. Alkaline PA and PB
3. Yolk-salt agar
4. Blood-sugar agar, Shaedler'
anaerobe agar
5. Endo's medium, MacConkey'

tinctorial properties of bacteria
beloning to Shigella genus:
1.
noncapsulated, nonmotile rods
2.
noncapsulated, nonmotile rods
3.
capsulated motile rods
4.
capsulated, nonmotile rods
5.
Gram positive sporing,
noncapsulated, motile rods
Bacteria of Shigella sonnei

ferment lactose:
1.
Till acid and gas
2.
Do not ferment
3.
Till hydrogene sulphide
4.
Till acid in 3-5 days
5.
Till acid and gas in 3-5
days
The most resistant species of
Shigella genus is:
1.
Sh.dysenteriae
2.
Sh.boydii
3.
Sh.flexneri
4.
Sh.sonnei
5.
All listed above
The pathogenicity of Shigella
spp. is connected with the
1.
2.
3.
4.
5.
()

of:
1.
2.
3.
4.
5.
Exotoxins
Endotoxins
Haemolysin
Fimbriae
All listed above
!!! (5)
?
1.
2.
3.
4.
5.
()
!!! (2,5)
?

:
1.
2.
examination
3.
examination
4.
5.
( )
!!! (2)
?

culture of

:
1.

tinctorial
2.
3.
4.
5.
!!! (1,2,3,4)
?

bacteria
()
():
1.

2.

3.

media
4.

5.
!!! (4)
?
Adhesion of Shigella spp. is

connected with the presence of:
1.
Flagella
2.
Fimbriae
3.
Endotoxins
4.
Exotoxins
5.
Microcapsule
The basic method of

microbiological diagnostics of
dysentery:
1.
Bacterioscopic
2.
Bacteriological
3.
4.
5.
Biological examination
Serological examination
Allergy diagnostic test
Identification of pure
Shigella spp. is carried out
according to the following
properties:
1.
Morphological and
2.
3.
4.
5.
Cultural
Biochemical
Antigenic
Toxigenic
Antigenic structure of
is analyzed with the help of the
following examination(s):
1.
Light microscopy
2.
Electronic microscopy
3.
Inoculation onto Hiss'
4.
5.
Slide agglutination test

Page typing
E. coli :
1.

2.
3.
4.
5.

!!! (1,3)
?

characteristics

endotoxins:
Enterobacteriaceae:
medium
1.
surrounding
2.

,

3.

are
4.

and
5.

!!! (2,3,4)
?

antigens of
Enterobacteriaceae:
1.
O
2.
W
3.
K
4.
F
5.
H
!!! (1,3,5)
?
:
Shigella
1.
O
2.
W
3.
K
4.
F
5.
H
!!! (1,3)
?
-:
1.
A B C D
2.
A B L
3.
A B C
4
O Vi
5
O Vi H
!!! (2)
?
The
located
1.
2.
3.
4.
5.
antigenes of E. coli are

in:
Cell wall
Mitochondria
Flagella
Nucleoid
All mentioned above
To point out the

of Enterobacteriaceae
1. Diffuse into surrounding
2.
Do not diffuse into
medium, are released only by

cell lysis
3. They are thermostable
4. Their physiological effects
nonspecific
5. Provoke haemolysis of sheep
human erythrocytes
To name the kinds of

1.
O
2.
W
3.
K
4.
F
5.
H
spp. antigens:
1.
O
2.
W
3.
K
4.
F
5.
H
To name the components of K
antigen:
1.
A B C D
2.
A B L
3.
A B C
4
O Vi
5
O Vi H
E. coli,
coli,

E.
E. coli ():
1.
O6, O15, O78, O148
2.
O124, O136, O143, O144
3.
O26, O55, O111, O142
4.
O254, O256, O348, O349
5.
O287, O288, O310, O311
!!! (3)
?
E. coli,
coli,

coli
E. coli ():
1 .
O6, O15, O78, O148
2.
O124, O136, O143, O144
3.
O26, O55, O111, O142
4.
O254, O256, O348, O349
5.
O287, O288, O310, O311
!!! (2)
?
E. coli,
coli,

E.
E. coli ():
1.
O6, O15, O78, O148
2.
O124, O136, O143, O144
3.
O26, O55, O111, O142
4.
O254, O256, O348, O349
5.
O287, O288, O310, O311
!!! (1)
?
E. coli O157:H7
O157:H7
coli,
1.
2.
3.
4.
5.
To name the serotypes of E.

wich relate to enteropathogenic
coli (EPEC):
1.
O6, O15, O78, O148
2.
O124, O136, O143, O144
3.
O26, O55, O111, O142
4.
O254, O256, O348, O349
5.
O287, O288, O310, O311
wich relate to enteroinvasive E.
(EIEC):
1.
2.
3.
4.
5.
O6, O15, O78, O148

O124, O136, O143, O144
O26, O55, O111, O142
O254, O256, O348, O349
O287, O288, O310, O311

wich relate to enterotoxigenic
coli (ETEC):
1.
O6, O15, O78, O148
2.
O124, O136, O143, O144
3.
O26, O55, O111, O142
4.
O254, O256, O348, O349
5.
O287, O288, O310, O311
Serotype of E. coli
belongs to the category of E.
which cause diarrhea
1.
Enteropathogenic
2.
Enteroinvasive
3.
Enterotoxigenic
4.
Enterohaemorrhagic
5.
Enteroaggregative
!!! (4)
?
E. coli
ferment
:
1.
2.
3.
4.
5.
!!! (1,2,3,4)
Enteropathogenic E. coli
till acid and gas:
1.
Glucose
2.
Lactose
3.
Maltose
4.
Mannitol
5.
Sucrose
?
E. coli
E.
():
help of
1.
-
2.
3.
4.
5.

test
!!! (2)
?

intestinal
:
1.

mucosa
2.

3.
SIgA
4.
flora of
5.

!!! (1,2,3,4,5)
?
E. coli
enteropathogenic

from
E. coli :
according to:
1.

2.

3.

4.

5.

slide

!!! (5)
?
,
using for

infections
, E. coli:
1.
2.
3.
4.
5.
-
bacteriophage
!!! (1,2,4,5)
?
The antigenic structure of

coli is determined with the
the reaction(s):
1.
Voges-Proskauer
2.
Agglutination test
3.
Precipitation test
4.
Neutralization test
5.
Complement fixation
The immunity to the

infections is provided by:
1.
Barrier function of
2.
gastric
3.
4.
5.
High acid reaction of

juice
sIgA
Phagocytes
Normal microbial
intestine
The colonies of
E. coli can be differentiated
nonpathogenic E. coli
1.
Morphological properties
2. Tinctorial properties
3.
Cultural properties
4.
Biochemical properties
5. Antigenic properties at
agglutination test with
polyvalent and monovalent
antisera
To name the medicines
treatment of intestinal
caused
1.
2.
3.
4.
5.
by E. coli:
Ampicillin
Probiotics
Benzylpenicillin
Chloramphenicol
Coli-proteus
,
is
,
spp.,
Lactobacillus spp., Bifidobacterium
Saccharomyces
spp., Saccharomyces boulardii .
:
1.
2.

3.

4.
5.
!!! (3,5)
?
,
infections,
E. coli:
coli:
1.

2.

infection
3.
4.

5.

!!! (1,2,3,4,5)
?

be

()
(probiotics):
1.
Lactobacillus acidophilus,
acidophilus,
Lactobacillus casei
2.
Bifidobacterium bifidum,
bifidum,
Bifidobacterium longum
3.
Streptococcus thermophilus
thermophilus
4.
Enterococcus faecium SF68
SF68
5.
Saccharomyces boulardii
boulardii
!!! (1,2,3,4,5)
?

typhoid
:
1.
S.typhi
2.
S.paratyphi A
3.
S.schottmuelleri
4.
S.typhimurium
5.
S.enteritidis
!!! (1)
?

(food
Biotherapeutic agents, that

drugs, containing Lactobacillus
Bifidobacterium spp.,
boulardii and etc., are:
1.
Antibiotics
2.
Killed bacteria
3.
Alive bacteria
4.
Prebiotics
5.
Probiotics

which can be caused by E.
1.
2.
Intestinal infections
Urinary tract
3.
4.
5.
Sepsis
Neonatal meningitis
Pyogenic infections
What microorganisms can

included in composition of
biotherapeutic agents
1.
Lactobacillus
Lactobacillus casei
2.
Bifidobacterium
Bifidobacterium longum
3.
Streptococcus
4.
Enterococcus faecium
5.
Saccharomyces
The infectious agent of

fever
1.
2.
3.
4.
5.
is:
S.typhi
S.paratyphi A
S.schottmuelleri
S.typhimurium
S.enteritidis
Salmonella gastroenteritis

caused
:
species:
1.
S.typhi
2.
S. typhimurium
3.
S.schottmuelleri
4.
S.choleraesuis
5.
S.enteritidis
!!! (2,4,5)
?

and

bacteria
Salmonella:
genus:
1.

nonsporing,
,
,
2.

nonsporing,
,
,
nonsporing,
3.

,
nonsporing,
,
sporing,
4.

, ,

5.

, ,

!!! (3)
?
Salmonella typhi
till
:
1.
2.
3.
4.
5.
!!! (1,3,5)
?

destroyed at
(100?C):
1.
1-2
2.
3.
20
4.
1
5.

poisoning) most frequently is

by the following Salmonella
1.
2.
3.
4.
5.
S.typhi
S. typhimurium
S.schottmuelleri
S.choleraesuis
S.enteritidis
To name the morphological
belonging to Salmonella
1.
Gram positive
noncapsulated, nonmotile
rods
2.
Gram negative
rods
3.
Gram negative
noncapsulated motile rods
4.
Gram negative
capsulated, nonmotile rods
5.
Gram positive
Salmonella typhi ferments

acid:
1.
2.
3.
4.
5.
glucose
lactose
maltose
sucrose
mannitol
Salmonella spp. are

boiling
1.
2.
3.
4.
5.
In 1-2 minutes
Instantly
In 20 minutes
In 1 hour
Are not destroyed
!!! (2)
?
Salmonella typhi
isolated
:
disease
1.
2.
3.
4.
5.
!!! (3)
?
Salmonella typhi
(haemoculture) of

with the
() ():
into
1.
2.
, Ma
3.
agar
4.
5.

!!! (4,5)
?
Salmonella typhi
(coproculture) of

with the
:
samples
1.
A
2.

3.
, Ma
4.
-
agar
5.
-
agar
!!! (3,4,5)
?

testing
,

of
:
1.
2.
3.
4.
5.

scarified
!!! (1,2,3,4,5)
Salmonella typhi are

during the first week of
from:
1.
2.
3.
4.
5.
Faeces
Urine
Blood
Bile
Sputum
Blood culture
Salmonella typhi is isolated
help of inoculation of blood
nutrient medium(a):
1.
PB
2.
Endo's agar, MacConkey's
3.
4.
5.
Ploskirev's medium
Rapport's medium
Bile broth
Faeces culture
Salmonella typhi is isolated

help of inoculation of faecal
onto nutrient medium(a):
1. PA
2. Rapport's medium
3. Endo's agar, MacConkey's
4.
Eosin-methylene blue (EMB)
5.
Bismuth-sulphite agar
To list the kinds of
material, which are used for

isolation of infectious agents
enteric
1.
2.
3.
4.
5.
fever:
Blood
Faeces
Urine
Bile
Material from
roseolas
?
(),
which

:
indirect
1.
(
)
2.

3.

4.

5.
-
!!! (4)
?
,
which

prevention of

:
vaccine
1.

2.
,
,

3.
TABte
4.
DPT
5.

!!! (1,2,3)
?
,
are

prophylaxis

:
vaccine
1.

2.
,
,

3.
TABte
4.
5.

!!! (4,5)
?
,
are

enteric
:
1.
(,
..)
2.

(, ,
)
3.
4.
,
To name the reaction(s),

is(are) used at serological
examination of enteric fever:
1.
RIHA (reaction of
haemoagglutination)
2.
Wright's reaction
3.
Wassermann's reaction
4.
Widal's reaction
5.
ELISA
To point out the remedies,

are used for specific
enteric fever:
1.
live oral mutant
2.
Specific injectable
purified Vi polysaccharide
vaccine
3.
TABte vaccine
4.
DPT vaccine
5.
Specific toxoid
To name the remedies, which

used for specific urgent
of enteric fever:
1.
live oral mutant
2.
Specific injectable
purified Vi polysaccharide
vaccine
3.
TABte vaccine
4.
Antibiotics
5.
Specific bacteriophages
To list the drugs, which

effective for treatment for
fever:
1.
Fluoroquinolones
(ciprofloxacin, pefloxacin
and etc.)
2.
The third generation of
cephalosporins (ceftriaxon,
ceftazidime, cefotaxime)
3.
Chloramphenicol
5.
!!! (1,2,3,4,5)
?

and

cholera
:
1.

, ,

2.

, ,

3.

, ,

4.

, ,

5.

, ,

!!! (2)
?
Vibrio cholerae
1.
2.
3.
4.
5.
!!! (1,4)
?
Vibrio cholerae
with

testing

medium(a):
() ()
1.
-
citrate2.
T (- -)
alkaline PB
3.

4.

5.
-
!!! (2,3)
?

material

4.
5.
Ampicillin, amoxycillin
Furazolidone
vibrios:
1.
Gram positive curved
asporogenous,
2.
Gram negative curved
asporogenous,
3.
Gram negative curved
asporogenous,
rods
4.
Gram positive straight
asporogenous,
5.
Gram negative straight
asporogenous,
Vibrio cholerae has got the

cell's components:
1.
Flagellum
2.
Spore
3.
Capsule
4.
Fimbria
5.
Inclusions
Pure culture of is isolated

the help of inoculation of
material onto nutrient
1.
2.
Yolk-salt agar
TCBS (thiosulphate-
bromthymol sucrose) agar

3.
Alkaline P and
4.
5.
Sabouraud's medium
Lowenstein-Jensen medium
To point out the testing

for bacteriological method of
:
1.
2.
3.
4.

5.
!!! (1,4)
?
Vibrio cholerae
:
1.
2.
3.
4.
5.
!!! (2,3,4)
?

properties of
Vibrio cholerae:
1.

2.
+
3.

4.
+
5.
+, +
!!! (1,2,3,5)
?
() () Vibrio
cholerae
:
of
1.
O1
2.
O25
3.
O38
4.
O124
5.
O139
!!! (1,5)
?
Vibrio cholerae
is

():
1.
A
2.
3.
4.

indirect
5.
(
()
)
!!! (1)
?
O1
Vibrio cholerae:
1.
2.
3.
diagnostics of cholera:
1.
Faeces
2.
Urine
3.
Blood
4.
Vomit (vomited matter)
5.
Sputum
Vibrio cholerae are able to
ferment till acid:
1.
arabinose
2.
mannose
3.
sucrose
4.
glucose
5.
lactose
To list biochemical
Vibrio cholerae:
1.
Nitrates are reduced to
nitrites
2.
Indole+
3.
Gelatin is liquefied
4.
Urease+
5.
Oxidase+, catalase+
What serovar(s) of Vibrio
cholerae is(are) responsible for
causing epidemics and pandemics
cholera:
1.
O1
2.
O25
3.
O38
4.
O124
5.
O139
Serovar of Vibrio cholerae
detected using reaction(s):
1.
Agglutination
2.
Precipitation
3.
Neutralization
4.
5.
RIHA (reaction of
haemoagglutination)
To name serotypes
cholerae serovar O1:
1.
Bengal
2.
Ogawa
3.
Inaba
of Vibrio
4.

5.
!!! (2,3,5)
?
O1
Vibrio cholerae:
1.
(holerae,
asiaticae)
asiaticae)
2.
3.
4.

5.
!!! (1,4)
?

susceptible
:
1.
2.
3.
4.
5.

!!! (1,3,4)
?
Vibrio cholerae
cholerae
:
of:
1.
2.
3.
4.
5.
!!! (1,2,3,4,5)
?
:
1.

2.

3.
-
4.
5.

!!! (1,6)
?

Vibrio
of
cholerae:
1.
- "-"
2.
"-"
3.
"-"
4.

B "-"
containing
5.

(C IV) "+"
4.
5.
El Tor
Hikojima
To name biotypes of Vibrio

cholerae of serovar O1:
1.
Cholerae (Classical,
2.
3.
4.
5.
Ogawa
Inaba
El Tor
Hikojima
Cholera vibrios are

to:
1.
2.
3.
4.
5.
Acids
Alkalis
Drying
Heating
All listed above
Pathogenicity of Vibrio
is connected with the presence

1.
2.
3.
4.
5.
Endotoxin
Exotoxin
Adhesion
Mucinase
Neiraminidase
To name ways of cholera

transmission:
1.
Contact way
2.
Inhalation way
3.
Ingestion way
4.
Congenital way
5.
All listed above
To point out differential
properties of classical biotype
Vibrio cholerae:
1.
Voges-Proskauer test "-"
2.
Haemolysis of sheep
erythrocytes "-"
3.
Hexamine test "-"
4.
Growth on medium
polymyxine B "-"
5.
Lysis by specific
bacteriophage (phage C IV)
"+"
!!! (1,2,3,4,5)
?

:
1.
- "+"
2.
"+"
3.
"+"
4.

B "+"
5.

containing
(El Tor II) "+"
To point out differential

properties of El Tor biotype of
Vibrio cholerae:
1.
Voges-Proskauer test "+"
2.
Haemolysis of sheep
erythrocytes "+"
3.
Hexamine test "+"
4.
Growth on medium
polymyxine B "+"
5.
Lysis by specific
bacteriophage
(phage El Tor II) "+"
!!! (1,2,3,4,5)
?

:
1.
2.
3.
4.
5.
(
(rapid
) -
,
.
!!! (1,2,3,4,5)
?
,
which
:
of
1.

2.

vaccine
3.

vaccine
vaccine
4.

phage
5.

!!! (1,2,3,4,5)
?
,
are
:
cholera:
1.

2.

3.
4.

To name methods of
cholera
1.
Bacterioscopic
2.
Biological
3.
Serological
4.
Bacteriological
5.
Express diagnostics
detection) Immunofluorescent test, the
reaction of immobilisation
of vibrios.
To point out the remedies,
are used for specific prevention
cholera:
1.
Specific live oral
2.
Specific killed oral
3.
Specific injectable
4.
Specific polyvalent
5.
Specific toxoid
To list the measures, which

suitable for treatment for
1.
Prompt and adequate
replacement of fluid
2.
Prompt and adequate
replacement of electrolytes
3.
Tetracyclins
4.
Specific polyvalent
phage
5.

!!! (5)
?

influenza
:
1.Orthomyxoviridae, Orthomyxovirus
2.Paramyxoviridae, Morbillivirus
3.Paramyxoviridae, Pneumovirus
4.Togaviridae, Rubivirus
5.Adenoviridae, Mastadenovirus
!!! (1)
?

:
to?
Orthomyxovirus
2.Paramyxoviridae, Paramyxovirus
!!! (2)
?

mumps

:
!!! (2)
?

measles
:
5.
All listed above
What family and genus do

viruses belong to?
1. Orthomyxoviridae,
Orthomyxovirus
2. Paramyxoviridae, Morbillivirus
3. Paramyxoviridae, Pneumovirus
4. Togaviridae, Rubivirus
5. Adenoviridae, Mastadenovirus

parainfluenza viruses belong
2.
3.
4.
5.
Paramyxoviridae, Paramyxovirus
Paramyxoviridae, Pneumovirus
Paramyxoviridae, Morbillivirus
Togaviridae, Rubivirus
What family and genus does

virus belong to?
1.
Orthomyxoviridae,
Orthomyxovirus
2. Paramyxoviridae, Paramyxovirus

virus belong to?
Orthomyxovirus
5.
!!! (4)
?

-
belong
:

respiratory syncytial virus
to?
1.
Orthomyxoviridae,
Orthomyxovirus
2. Paramyxoviridae,
Paramyxovirus
Morbillivirus
3.
4.
Paramyxoviridae,
5.
!!! (3)
?
rubella

:
1. Orthomyxoviridae, Orthomyxovirus
Paramyxovirus
Morbillivirus
!!! (5)
?

:
1. Orthomyxoviridae, Orthomyxovirus
!!! (5)
?

Herpesviridae,
Alphaherpesvirinae:
1. 1
2. 2
3.

4.
5. -
!!! (1,2,3)
?
virus belong to?

1.
Orthomyxoviridae,
Orthomyxovirus
2. Paramyxoviridae,
3.
4.
Paramyxoviridae,
5.

adenoviruses belong to?
1.
Orthomyxoviridae,
Orthomyxovirus
What virus concern family
Herpesviridae, subfamily
Alphaherpesvirinae?
1. Herpes simplex virus type 1
3. Herpes zoster virus
4. Cytomegalovirus
5. Epstein-Barr virus

Herpesviridae,
Betaherpesvirinae:
1. 1
2. 2
3.

4.
5. -
!!! (4)
?
What viruses concern family

Betaherpesvirinae?
3. Herpes zoster virus
4. Cytomegalovirus
5. Epstein-Barr virus

Herpesviridae,
Gammaherpesvirinae:
1. 1
What viruses concern family

Gammaherpesvirinae?
1.
Herpes simplex virus type 1
2. 2
3.

4.
5. -
!!! (5)
?

:
1.
pleomorphic
( ),

,
2.-
3.
,

,
-
4. ,

+
5. ,

6. ,

!!! (1)
?

:
1.
( ),

a
,
segmented,
-
2.
,

and
,
stranded,
-
3. ,

single +
4. ,

linear

2.
3.
4.
5.

Herpes zoster virus
Cytomegalovirus
Epstein-Barr virus
To name the features of the

nucleocapsid structure and the
genome type of influenza viruses:
1. Enveloped virus of
2.
3.
4.
5.
form (spherical or tubular)

with a helical nucleocapsid
and segmented, single-stranded
RNA of negative-polarity
Enveloped virus of spherical
shape with a helical
nucleocapsid and unsegmented,
linear single-stranded,
negative-polarity RNA
Enveloped virus with an
icosahedral nucleocapsid and
single-stranded, positivesense RNA
Nonenveloped virus with an
linear double-stranded DNA

genome type of parainfluenza
viruses:
1. Enveloped virus of pleomorphic
form (spherical or tubular) with
helical nucleocapsid and
single-stranded RNA of negativepolarity
2.
shape with a helical nucleocapsid
unsegmented, linear singlenegative-polarity RNA
3.Enveloped virus with an
stranded, positive-sense RNA
4.Nonenveloped virus with an
double-stranded DNA
5. ,

linear

!!! (2)
?

:
1.
( ),
a

segmented,
,
-
2.
,
and

stranded,
,
-
3. ,
single
+
4. ,
linear

5. ,
linear

!!! (2)
?

:
1.
( ),
a

,
-
2.
shape
,

,
-
3. ,

+
4. ,
an


double-stranded DNA
genome type of mumps virus:
2.
3. Enveloped virus with an
4.
double-stranded DNA
5.
double-stranded DNA

genome type of measles virus:
segmented, single-stranded RNA of
negative-polarity
2.Enveloped virus of spherical
with a helical nucleocapsid and
unsegmented, linear singlestranded, negative-polarity RNA
3.
single-stranded, positive-sense
RNA
4.
Nonenveloped virus with
5. ,

!!! (2)
?

genome
- :
virus:
1.
( ),
a

,
-
2.
shape
,

,
-
3. ,

+
4. ,

5. ,

!!! (4)
?

genome
:
1.

pleomorphic
( ),
with a

segmented,
,
negative -
2.

shape
,

stranded,
,
-
3.
,
single
+
4.
,
5.
type of respiratory syncytial
segmented, single-stranded RNA of
negative-polarity
2. Enveloped virus of spherical
unsegmented, linear singlestranded, negative-polarity RNA
single-stranded, positive-sense
RNA

type of rubella virus:
1.
Enveloped virus of
form (spherical or tubular)
single-stranded RNA of
polarity
3.
4.
linear

5.
,
linear

!!! (3)
?

genome
:
1.
pleomorphic
( ),
a

segmented,
,
-
2.
shape
,

stranded,
,
-
3. ,
single
+
4. ,
linear

5. ,
linear

!!! (4)
?

genome
:
1.
( ),
a

segmented,
,
-
2.
shape
,

stranded,
,
double-stranded DNA
5.
double-stranded DNA

type of adenoviruses:
1.
Enveloped virus of
double-stranded DNA
double-stranded DNA

type of herpesviruses:
3. ,
single
+
4. ,
linear

5. ,
linear

!!! (5)
?

is

:
1.
immunoglobulin
2.
3.
4.
5.
!!! (2,3,4,5)
?

is

:
1.
2.
3.
4.
5.
!!! (1)
?
:
are:
1.

A
2.

B
3.

influenza C
4.
first
24 - 48
5. 2,

double-stranded DNA
double-stranded DNA
What type of biopreparations

used for the formation of active
immunity against influenza:
1.
Anti-influenza
2.
3.
4.
5.
Live vaccine
Inactivated corpuscular
vaccine
Inactivated subunit vaccine
Inactivated splint vaccine

used for the formation of passive
immunity against influenza:
1. Anti-influenza immunoglobulin
2.
Live vaccine
3.
Inactivated corpuscular
vaccine
4. Inactivated subunit vaccine
5. Inactivated splint vaccine
Amantadine and rimantadine

1. Remedies for chemoprophylaxis
and chemotherapy of influenza
and chemotherapy of influenza
and chemotherapy of
4. Effective only during the
24 to 48 hours of disease
5.
Their target is M2 protein,

channel
!!! (1,4,5)
?

is

:
1.
2.
3. ()
4.
5.MMR
!!! (2,5)
?

is
:
1.

2.

3.
()
4.
5.
MMR
which functions as an ion

used for prophylaxis of mumps:
1.
No biopreparations
2.
Live attenuated vaccine
3. Killed (inactivated) vaccine
4.
Anatoxin (toxoid)
5.MMR vaccine (mumps, measles,
rubella)

used for prophylaxis of measles:
1. No biopreparations
2. Live attenuated vaccine
4. Anatoxin (toxoid)
5. MMR vaccine (mumps, measles,
rubella)
!!! (2,5)
?

is

:
1.
2.
3. ()
4.
5. MMR
!!! (2,5)
?

is

adenovirus
:
1.
2.
3. ()
4.
5.
!!! (2)
?

is
herpesvirus
:
1.

used for prophylaxis of rubella:
1.
No biopreparations
3.
Killed (inactivated) vaccine
4.
Anatoxin (toxoid)
5.
MMR vaccine (mumps, measles,
rubella)

used for prophylaxis of
infection:
1. No biopreparations
2. Live vaccine
4. Anatoxin (toxoid)
5. Specific immunoglobulin

infections:
1.
No biopreparations
2.
3. ()
4.
5.
!!! (2,5)
?
:
infect:
1.
2.
3.

4.
5.
!!! (1,3,4)
?
:
cause:
1. ,
2.
3.
keratoconjunctivitis
4.
5.
()
!!! (1,2,3,4,5)
?

cultivated
:
1.

2.

3.
: 199,
199,
,
4.
origin
5.

!!! (4)
?
:
1. -
to
-
host
2. -
24
in
3. -

to

4. -
resulting
,
2.
3.
4.
5.

Killed (inactivated) vaccine
Anatoxin (toxoid)
Specific immunoglobulin
Adenoviruses are able to
1.
Lymphoid tissue
2.
Nervous tissue
3.
Epithelial cells of
respiratory and intestinal tracts
4.
Conjunctiva
5.
All listed above
Adenoviruses are able to

1.
2.
3.
4.
5.
Phapyngitis, tonsillitis
Pneumonia
Epidemic
Diarrhea
Acute respiratory diseases
(ARD)
Adenoviruses can be
in:
1.
2.
3.
Laboratory animals
Chicken embryo
Nutrient media: medium
lactic albumin hydrolysate,

Eagle's medium
4.
Cell cultures of human
5.
Blood MPB
Features of pathogenesis of
herpes infections:
1.
Herpes viruses are able
form proviruses in genome of
cell
2.
Herpes viruses are kept
blood during 24 hours

3.
Herpes viruses are able
provoke acute infection of
central nervous system,
in the fatal outcome

long

5. -
with

!!! (1,4,5)
?
- :
1.
2.
mediated
3.

immune
,

infectious
4.
the

5.

in
!!! (5)
?
1
is

:
1.,
2.
3.
4.
5.,
!!! (1,2,4,5)
?
2
is

the
:
1. ,
2.
3.
4.
5. (,
lesions
4.
Herpes viruses persist
time in the ganglia, causing the

chronic and latent infection
the periodic aggravations
5.
Herpes viruses cause the
vesicular lesions of skin and
mucosa
Herpes infection is
characterized:
1.
Suppression of cellimmunity
2.
Suppression of humoral
response
3. Herpes viruses form
immune complexes which damage
tissues
4.
Herpes viruses take part
allergization of organism
5.
All mentioned above

responsible for development of
the following diseases:
1. Gingivostomatitis, pharyngitis
2. Herpes labialis
3.
Genital herpes
4.
Keratoconjunctivitis
5.
Encephalitis, pneumonia

following diseases:
1. Gingivostomatitis, pharyngitis
2.Herpes labialis
3. Genital herpes
4. Keratoconjunctivitis
5. Neonatal herpes (encephalitis,
pneumonia, painful vesicular
of skin, mucosa, eyes)
!!! (3,5)
?

characterized:
:
male
1.

2.
3.
contacts in
4.
the
5.

!!! (1,2,3,4,5)
?
Herpes Varicella-zoster

the
:
1.

children
2.

3.

4.

5.

!!! (1,4)
?

responsible
:
1.

2.
3.

mononucleosis
4.
,

, ,

5.

!!! (1,2,3,4,5)
?
-
responsible
:
1.
2.
3.
4.
children
()
of
5. ,
Genital herpes is
1.
Painful vesicular lesions of
and female genitals and anal area

2. Fever
3.Inguinal lymphoadenopathy
4. Dysuria
5. Transmission by sexual
adults and during passage through
birth in neonates
Herpes zoster virus is

following diseases:
1.Varicella (chickenpox) in
2.
3.
4.
5.
Herpes labialis
Genital herpes
Herpes zoster in adults
All listed above
Cytomegalovirus is
for development of the following
diseases:
1. Latent infection
2. Post-transfusion
3. Congenital malformations
4. Generalised infection
associated with
hepatosplenomegaly, jaundice,
thrombocytopenic purpura and
haemolytic anemia
5. Pneumonia and hepatitis in
immunocompromised patients
Epstein-Barr virus is
for development of the following
diseases:
1. Infectious mononucleosis
2. Burkitt's lymphoma
3.Varicella (chickenpox) in
4.Nasopharyngeal carcinoma in men
China
5.
Lymphomas in immunodeficient
persons such as AIDS patients and
transplantant recipients
!!! (1,2,4,5)
?

viruses
:
carried
1.
2.
3.
-
4.
5.
-
!!! (4,5)
?
:
virus
1.
2.
3. -
4. -
5.
The dividing of influenza

into A, B, C serogroups is
out according to:
1.
Haemagglutinin
2.
Neurominidase
3.
RNA-polymerase
4.
Ribonucleoprotein
5.
-protein
The envelope of influenza
contains:
1. Haemagglutinin
2. Neurominidase
3. RNA-polymerase
4. -protein
5. Endonuclease
!!! (1,2)
?
()
:
virus:
1.
2.
3.
-
4
5.
!!! (1,2,3,4,5)
?
()
:
1.

2.

()
3.

4.
5.

!!! (1,2,3,5)
?

:
1. (sIg A, Ig G)
To name the property(ies) of

haemagglutinin of influenza
1. It is glycoprotein
2. It is type-specific antigen
3. It is receptor for attachment
of virus to host cells
4. Causes agglutination of
erythrocytes
5. Provokes haemolysis
To name the property(ies) of
neuraminidase of influenza virus:
1. It is glycoprotein and typespecific antigen
2. It is enzyme cleaving
neuraminic (sialic) acid
3. Degrades the protective layer
of mucus in the respiratory tract
4. Causes agglutination of
erythrocytes
5. Facilitates the release of
virus progeny from the infected
cell
To name the factors of innate
immunity to influenza:
1. Antihaemagglutitin (sIg A, Ig
G)
2. (sIg A, Ig G)
G)
3.
4.
5.
T-
!!! (3,4)
?

acquired
:
1. (sIg A, Ig G)
G)
2. (sIg A, Ig G)
G)
3.
4.
5.
T-
!!! (1,2,5)
?
,
-, -:
1.
Picornaviridae
2.
Paramyxoviridae
3.
Rabdoviridae
4.
Togaviridae
5.
Flaviviridae
!!! (1)
?

genome
:
1.
,

RNA
+
2.
shape
,

stranded,
, ,
-
shape
3. ,

polarity
-
4. ,

linear

2. Antineuraminidase (sIg A, Ig
3. Interferon
4. Natural killer cells
5. Specific sensibilized Tlymphocytes
To name the factors of

immunity to influenza:
1. Antihaemagglutitin (sIg A, Ig
2. Antineuraminidase (sIg A, Ig
3. Interferon
4. Natural killer cells
5. Specific sensibilized Tlymphocytes
To name the family of

polioviruses, coxackieviruses,
echoviruses:
1.
Picornaviridae
2.
Paramyxoviridae
3.
Rabdoviridae
4.
Togaviridae
5.
Flaviviridae
type of polioviruses:
1.Nonenveloped virus of spherical
form with icosahedral symmetry of
nucleocapsid and single-stranded
of positive-polarity
3. Enveloped virus of bullet
single-stranded, negativeRNA
double-stranded DNA

5. ,
linear

!!! (1)
?

cultivated
:
1.
2.
3. : 199,
,
Eagle's
4.
5. M, M
origin
!!! (4)
?
,
which

:
1.
2.
3.
4.
5.
!!! (2)
?

:
1.
2.
3.
4.
5.
!!! (1,2,3,4)
?
-
are
:
1.
intestine
,
2. ( )
pharyngitis)
3.
,
rashes of
4.
(
)

double-stranded DNA
Polioviruses can be
in:
1. Laboratory animals
2. Chicken embryos
3. Nutrient media: medium 199,
lactic albumin hydrolysate,
medium
4. Tissue cultures of primate
5.
Serum MPA, blood MPB

To point out the reaction,
is used for differentiation of

serotypes of polioviruses:
1. Slide agglutination
2. Neutralization test
3. Precipitation test
4. Complement fixation test
5. Reaction of inhibition of
haemagglutination
Point out the clinical
manifestations of poliomyelitis:
1. Inapparent infection
2. Abortive infection
3. Nonparalytic form
4. Paralytic form
5. Interstitial pneumonia
Coxackieviruses of group
responsible for:
1. Acute respiratory and
infections, aseptic meningitis
2. Herpangina (vesicular
3. Hand, foot and mouth disease
(epidemics of fever with
maculopapular or vesicular
these zones)
4. They are characterized with
tropism to nervous tissue (they
cause
5.
( )
!!! (1,2,3,5)
?
-
are
:
1.
intestine
,
2. ( )
pharyngitis
3.
,
rashes of
4.
(
)
caus
5.
( )
!!! (1,4)
?
- :
1.
viruses)
2.
3.
4.
aseptic
5.

!!! (1,2,3,4,5)
?
()

:
1.
2.
()
3. ()
vaccine
4.
5.
!!! (2,3,5)
?
encephalomyelitis)
tropism to muscular tissue (they
cause paralysis)
Coxackieviruses of group B
responsible for:
1. Acute respiratory and
infection, aseptic meningitis
2. Herpangina (vesicular
3. Hand, foot and mouth disease
(epidemics of fever with
maculopapular or vesicular
these zones)
tropism to nervous tissue (they
encephalomyelitis)
tropism to muscular tissue (they
cause paralysis)
Viruses (Enteric
Cytopathogenic Human Orphan
are characterized:
1. They are not pathogenic for
laboratory animals
2. They are able to cause
asymptomatic infection
3. They are able to provoke
meningitis
4. They are responsible for
gastroenteritis
5. They are causative agents of
respiratory diseases
To list the remed(y)ies for
specific prophylaxis of
poliomyelitis:
2.
Anatoxin (toxoid)
3.
Live attenuated (Sabin)
vaccine
4.
Inactivated (Salk)
5.
6.
Bacteriophage
Human immune globulin

, :
virus:
1.
Picornaviridae
2.
Paramyxoviridae
3.
Rabdoviridae
4.
Togaviridae
5.
Flaviviridae
!!! (3)
?

:
1.
spherical
,

RNA
+
2.
,
and

stranded,
, ,
-
3. ,

polarity
-
4. ,

linear

5. ,
linear

!!! (3)
?

is
:
1.
2.
mucosa of
,
3.
by
4.
5.
sensitivity
To name the family of rabies

virus, vesicular stomatitis
1.
2.
3.
4.
5.
Picornaviridae
Paramyxoviridae
Rabdoviridae
Togaviridae
Flaviviridae

genome type of rabies virus:
1. Nonenveloped virus of
form with icosahedral symmetry of
nucleocapsid and single-stranded
of positive-polarity
3.Enveloped virus of bullet shape
single-stranded, negativeRNA
4. Nonenveloped virus with an
double-stranded DNA
double-stranded DNA
Vesicular stomatitis virus

characterized:
1. Concerns group of arboviruses
2. Causes vesicular rash on
oral cavity, pharynx
3. This viruses are transmitted
mosquitoes
4. This viruses stimulate a
interferon production
5. This viruses are highto interferon
!!! (1,2,3,4,5)
?
:
1.
Lyssavirus Rabdoviridae
2.

to a
3.
(
damaged
)
with the
4.
demyelination)

and the
5.

result of
!!! (1,2,3,4,5)
?

specific
:
1.

immunization in

2.

3.

diploid

4.
(
)
5.

!!! (1,2,3,4,5)
?

hepatitis A
1. Caliciviridae
2. Picornaviridae
3. Hepadnaviridae
4. Flaviviridae
5.
!!! (2)
?

hepatitis B
:
1.

2.
Hepadnaviridae
3.
Flaviviridae
4.
Caliciviridae
5.
Picornaviridae
!!! (2)
Rabies is characterized:
1. Causative virus belongs to
Lyssavirus genus of Rabdoviridae
family
2. This disease is transmitted
man by the bite of rabid animal
3. Central nervous system is
(development of encephalitis
death of neurons and
4. There are the violent form
paralysis form of illness
5. The death occures in the
respiratory arrest
To list the measures for

prophylaxis of rabies:
1. Adequate antirabies
animals
2.Administration of human rabies
immune globulin
3.Usage of inactivated human
rabies vaccine
4.Pre-exposure vaccination (with
preventive aim)
5.Postexposure vaccination (with
therapeutical aim)
virus:
1. Caliciviridae
2. Picornaviridae
3. Hepadnaviridae
4. Flaviviridae
5. Not classified
virus:
1.
2.
3.
4.
5.
Not classified
Hepadnaviridae
Flaviviridae
Caliciviridae
Picornaviridae
?

hepatitis C
:
1.
Picornaviridae
2.
Caliciviridae
3.
Flaviviridae
4.
Hepadnaviridae
5.

!!! (3)
?

hepatitis D
D:
1.
Flaviviridae
2.
Picornaviridae
3.
Hepadnaviridae
4.
Caliciviridae
5.

!!! (5)
?

hepatitis E
:
1.
Hepadnaviridae
2.
Picornaviridae
3.
Flaviviridae
4.
Caliciviridae
5.

!!! (4)
?
-
transmission is
:
1.
2. B
3. C
4. D
5. E
!!! (1,5)
?
(
(by
, )
:
1.

2.
B
3.
C
4.
D
5.
E

virus:
1.
2.
3.
4.
5.
Picornaviridae
Caliciviridae
Flaviviridae
Hepadnaviridae
Not classified

virus:
1.
2.
3.
4.
5.
Flaviviridae
Picornaviridae
Hepadnaviridae
Caliciviridae
Not classified

virus:
1.
2.
3.
4.
5.
Hepadnaviridae
Picornaviridae
Flaviviridae
Caliciviridae
Not classified
Fecal-oral rout of
characteristic for
1.
Hepatitis A
2.
Hepatitis B
3.
Hepatitis C
4.
Hepatitis D
5.
Hepatitis E
virus
virus
virus
virus
virus
Parenteral way of transmission

blood, by sexual intercourse,
during birth) is characteristic
for
1.
Hepatitis A virus
2.
Hepatitis B virus
3.
Hepatitis C virus
4.
Hepatitis D virus
5.
Hepatitis E virus
!!! (2,3,4)
?
:
1.
Hepatitis A virus is
characterized:
2.
3.

4.

5.
effect
1.Multiplies in the intestinal

epithelium
2. Reaches the liver by the
haematogenous way
3.Does not show the direct
cytopathic effect for hepatocytes
4. Shows the direct cytopathic
for hepatocytes
5. Injury of hepatocytes is caused
by
immune attack by cytotoxic T cells
!!! (1,2,3,5)
?
specific

:
1.
2.
3.
4.
immunoglobulin
5.
!!! (2,3,5)
?

:
1.

,
on

2.

serum

3.

4.

5.

!!! (1,2,3,4)
?

virus
:
1.
animal

2.

3.

4.

5.

!!! (4)
?
To list the remedies for

prophylaxis of hepatitis A:
1.
Anatoxin (toxoid)
2.
3.
Inactivated vaccine
4.
Bacteriophage
5.
Normal human
Hepatitis B surface antigen

(HbsAg) is characterized:
1. Is glycoprotein with lipid
component of viral envelope
2. Is receptor for its adsorbtion
hepatocytes
3. Joins the albumin of blood
4. Has immunogenic properties
5. Has not immunogenic properties
Reproduction of hepatitis B
occurs in:
1.
Cell culture of human and
origin
2.
3.
4.
5.
Chicken embryos
Intestinal epithelium
Nucleus of hepatocytes
All listed above

body
:
1.
action
2.
3.
4. Tmacrophages,
(T-), ,
.e.
and
5.

!!! (2,3,4,5)
?

markers
:
1.
HBsAg
2.
HBcAg
3.
IgM antiHBc
antigen)
4.
antiHBs
5.

Hepatitis B virus in human

is able:
1. To show direct cytopathic
2. Not to show direct cytopathic
action
3. To integrate its genome into
genome of hepatocytes
4. To suppress activity of Tlymphocytes (T-helpers),
i.e. to provoke immunodeficiency
condition
5. To be a cause for cirrhosis
hepatocellular carcinoma
To point out the specific

of acute hepatitis B infection:
1.
HBsAg (hepatitis B surface
antigen)
2.
HBcAg (hepatitis B core
3.
4.
5.
!!! (1,3,5)
?

virus
:
1. 6
(pH
(pH 2)
2. 121grC
15
3. 121grC
30
4. (160grC)
45
5. (160grC)
60
IgM antiHBc-antibody
antiHBs-antibody
DNA of hepatitis B virus
Infectivity of hepatitis B
is lost after:
1.Exposure to acids for 6 hours
2 )
2.Autoclaving at 121grC for 15
minutes
3.Autoclaving at 121grC for 30
minutes
4. Sterilization with dry heat
(160grC) for 45 minutes
5.Sterilization with dry heat
(160grC) for 60 minutes
!!! (3,5)
?
To name the remedies for
specific
()
:
1.
2.
vaccine
3. -
prophylaxis of hepatitis B:
2. Inactivated vaccine
3. Genetically engineered
4. Specific immune globulin
()
4.
5.
5. Antitoxic serum
!!! (2,3,4)
?
:
1.
Hepacivirus
Flaviviridae
2. - , +
3. - , -
4.
,

5.
virus

Hepatitis C virus is
characterized:
1.Concerns genus Hepacivirus of
family Flaviviridae
2.Has genome - single-stranded,
positive-sense RNA
3.Has genome - single-stranded,
negative-sense RNA
4.Infection provoked by this
is spread parenterally by blood,
sexually, by vertical way
virus
is associated with cirrhosis and
!!! (1,2,3,5)
?
:
1. Caliciviridae,
- , +
has
2.
positive -
3.
virus
,
rout

virus
4.
limited

virus
5.

virus
(
)
(especially
Hepatitis E virus is
characterized:
1. Concerns family Caliciviridae,
genome - single-stranded,
sense RNA
2. Infection provoked by this
is transmitted by fecal-oral
3. Infection provoked by this
is generally mild and self
with low fatal outcome
is associated with cirrhosis and
demonstrates high rate of fatal
outcome in pregnant women
in the third trimester of
pregnancy)
!!! (1,2,3,5)
?

(HIV)

Human immunodeficiency virus

can join the following cells:
:
receptors)
1.
CD4+ ( CD4
)
2. - ()
macrophages
3.
B-
nervous
4.
5.

1. CD4+ cells (possess CD4

2. -lymphocytes (helpers)
3. Some of B-lymphocytes
4. Some of monocytes and
5. Glial cells in the central
system
!!! (1,2,3,4,5)
?

virus is
:
1.

2.

cone
3. ,
, +
stranded,
4.
( CD4
,
CD4
- gp120)
cells,
5. (
,
- gp41)
Human immunodeficiency
characterized:
1. It is enveloped virus of
spherical form
2.Its nucleocapsid has an outer
icosahedral shell and an inner
shaped core
3.Its genome is diploid, composed
of two identical singlepositive-sense RNA
4. Has knob-like spikes of the
envelope surface (they join the
receptors on susceptible host
they are spike antigen - gp120)
5.Has the transmembrane pedicles
(they are cause for cell fusion,
transmembrane pedicle protein -
gp41)
!!! (1,2,3,4,5)
?

Human immunodeficiency virus
is
:
characterized:
1. Lentivirus
1. Belongs to genus Lentivirus
of
Retroviridae
family Retroviridae
2.
2.Has reverse transcriptase
enzyme
3.DNA-copy of its genome can

3. -
integrate into the host cell
chromosome (provirus formation)
( )
4.Causes selective T cell
deficiency
4. -reduction in number of CD4+
- CD4+ ells, inversion of CD4+/CD8+
ratio
, CD4+/CD8+ 5.Its ways of transmission -
through
is
5. -
,
( ,
),

, .
!!! (1,2,3,4,5)
?
-
manifestations

():
infection
1.
(,
)
2.
simplex
(Mycobacterium tuberculosis,
Mycobacterium avium-intracellulare)
infection
3.
,
intracellulare)
(,
Pneumocystis carinii)
(Candidiasis,
4. ( ,
)
sarcoma,
5. -
lymphomas)
sexual contacts (because virus

present in semen, vaginal
secretions), by contact with
contaminated blood and blood
products, by transplacental way.
To point out the

associated with Human
immunodeficiency virus
and Acquired immunodeficiency
syndrome (AIDS):
1.Opportunistic viral infection
(Cytomegalovirus, Herpes
virus)
2.Opportunistic bacterial
(Mycobacterium tuberculosis,
Mycobacterium avium3.Opportunistic mycotic and
parasitic infection
Pneumocystis carinii pneumonia)
4.Malignancies (Kaposi's
Hodgkin and non-Hodgkin
5.AIDS-related dementia
!!! (1,2,3,4,5)
?

:
after:
1. 30
minutes
56 . C
2. ,
peroxide,
, 0,3% ,
2% ,
.. 10
to
3.
, , 0,3%
flutaraldehyde
, 2%
4.

Infectivity of Human
immunodeficiency virus is lost
1. Heating at 56gradC for 30
2. Treating with many detergents,
iodophores, 0,3% hydrogen
2% flutaraldehyde, etc. in 10
minutes
3. Virus is exclusively resistant
many detergents, iodophores, 0,3%
hydrogen peroxide, 2%
4. Virus is very sensitive to
ultraviolet radiation
5.Virus is very resistant to
ultraviolet radiation resistant
5.

!!! (1,2,4)
?
()
laboratory
-:
1. ()
2. ()

3. ()
assay

antigens
4. ( )
assay

5. ( )

test)
To name method(s) of
diagnostics of Human
immunodeficiency virus (HIV)
infection:
1.Polymerase chain reaction (PCR)
2. Enzyme-linked immunosorbent
(ELISA) for detection of HIV
(ELISA) for detection of HIV
antibodies
4.Immunoblotting (Western blot
for detection of HIV antigens
5.Immunoblotting (Western blot
test)
for detection of HIV antibodies
!!! (1,2,3,5)
?
()
cultivation
:
1.

2.

3.
CD4+
CD4+
4.
CD8+
5.

To name method(s) of
of Human immunodeficiency virus
infection:
1. In laboratory animals
2. In chicken embryos
3. In continuous cell culture
lymphocytes
4.In continuous cell culture CD8+
lymphocytes
5.Can not be cultivated
!!! (3)
?
:
immunodeficiency
1.

2." "

3.
-
newborns
4.
5.
!!! (1,2,3,5)
To point out the measures of

prophylaxis of Human
virus (HIV) infection:
1.Screening of blood prior to
transfusion for detection of the
presence of specific antibodies
2."Safe sex" including the use of
condoms
3.Specific drug therapy to HIVinfected mothers and their
4.There are the vaccines
5.There is no vaccine
?

:
1. , , ,

2. , , ,

3. , , ,

4. , , ,

5. , ,
,

!!! (5)
?
() ()
for
:
1.
M
2.

3.

4.
-
5.
-
!!! (4,5)
?

:
1.
2.
3.

4.

5.
,
!!! (1,3,4,5)
?

:
1.
2.
3.
4.

toxin
(epidermolytic)
5.
()
!!! (1,2,3,4,5)
?

:

staphylococci:
1.Gram positive nonsporing,
noncapsulated, nonmotile cocci
arranged in grape-like
clusters
2.Gram negative nonsporing,
clusters
arranged in chains
arranged in chains
5.Gram positive nonsporing, with
microcapsule, nonmotile cocci
clusters
To name the elective medium(a)
isolation of staphylococci:
1.
Alkaline MPB and MPA
2.
Blood MPA
3.
Bile agar
4.
Yolk-salt agar
5.
Milk-salt agar
To list the factors of
pathogenicity of staphylococci:
1.
Exotoxins
2.
Endotoxin
3.
Extracellular enzymes
4.
Cell surface proteins
5.
Cell associated polymers
To list the exotoxins of

staphylococci:
1.
Haemolysin
2.
Leikocidin
3.
Enterotoxin
4.
Toxic shock syndrome
5.
Exfoliative
toxin
To point out the extracellular

enzymes of staphylococci:
1.
2.
3.
4.
(-a, -a)
5.
!!! (1,2,3,4,5)
?

:
1.
2.
3.
4.
5. beta-
!!! (1,2,3,4,5)
?

bacteria

() ():
1.

2.
-
3.

4.
-
5.
, Ma
medium
!!! (4)
?

them
() ():
1.

2.
-
3.

4.
-
5.
, Ma
medium
!!! (3)
?
()
,
:
1.

2.

3.
-
4.
-
5.

!!! (1,3,4)
?
Staphylococcus aureus
:
1. ,

2.
3.
1 Coagulase
2. Hyaluronidase
3. Fibrinolysin
4. Nucleases (DNA-ase, RNA-ase)
5. Proteinases
To point out the extracellular
enzymes of staphylococci:
1 Lecithinase
2. Lipases
3. Urease
4. Catalase
5. beta-lactamases
Lecithinase activity of
is detected by inoculation onto
nutrient medium(a):
1 Sugar MPA
2. Milk-salt agar
3. Blood agar
4. Yolk-salt agar
5. Endo's medium, MacConkey's
Haemolytic activity of bacteria

is detected by inoculation of
onto nutrient medium(a):
1 Sugar MPA
2. Milk-salt agar
3. Blood agar
4. Yolk-salt agar
5. Endo's medium, MacConkey's
To point out what kind(s) of

lesions can be caused by
staphylococci:
1. Wound infection
2. Venereal diseases
3. Pyogenic-inflammatory lesions
4. Toxin-mediated illnesses
5. All mentioned above
Staphylococcus aureus are

responsible for the following
disease(s):
1. Skin, mucosa and soft tissue
infections
2. Osteomyelitis and arthritis

tract
4.-
( ,
,
)
5. ,

!!! (1,2,3,4,5)
?

:
1.
2.
3.
4.
5.
!!! (1,2)
?

performed
:
1.
.
2.

the

3.

culture
4.

5.

!!! (2,3)
?

StreptococStreptococcus pyogenes:
1.- ,
with
, ,

2.- ,
, ,
3.- ,
, ,
4.- ,
, ,

5.- ,
3. Infections of a respiratory
and the paranasal sinuses
4. Toxin-mediated illnesses (food
poisoning, toxic shock syndrome,
scalded skin syndrome)
5. Sepsis, central nervous system
infections
To name the methods of
staphylococcal infections:
1. Microscopic
2. Bacteriological
3. Serological
4. Biological
5. Skin-allergic test
Bacteriophage typing is
with the purpose(s):
1. Isolation of a pure culture of
bacteria
2. Recognition of a source and
ways of spread of an infection
3. Identification of a pure
of bacteria
4. Detection of sensitivity to
antibiotics
5. Detection of the pathogenicity
factors
cus pyogenes:
1. Gram positive nonsporing,
arranged in grape-like clusters
nonmotile cocci arranged in
chains, which are able to have
capsules
chains, which are able to have
capsules
4. Gram negative nonsporing, with
5. Gram positive nonsporing,
nonmotile "lancet-shaped" cocci
in pairs (diplococci) surrounded
,
with capsules

!!! (3)
?


StreptococStreptococcus pneumoniae:
cus pneumoniae:
1.- , 1.Gram positive nonsporing, with
, , microcapsule, nonmotile cocci


2.
2.- , nonmotile cocci arranged in
, chains, which are able to have
,
capsules
3.
3.- , nonmotile cocci arranged in
, chains, which are able to have
,
capsules
4Gram negative nonsporing, with

4.- , microcapsule, nonmotile cocci
, , arranged in grape-like clusters

5.

5.- , in pairs (diplococci) surrounded
,
with capsules

!!! (5)
?
Streptococcus pyogenes
The colonies of Streptococcus
:
pyogenes on blood MPA have:
1.
1. Large size
2.
2. Small size
3.
3. No zones of haemolysis around
them
4. alfa-zones of haemolysis
around
4. -
them
5. beta-zones of haemolysis
around
5. -
them
!!! (2,5)
?
Streptococcus
The colonies of Streptococcus
pneumoniae :
pneumoniae on blood MPA have:
1.
1. Large size
2.
2 Small size
3.
3. No zones of haemolysis around
them
4. -
4. alfa-zones of haemolysis
around
them
5. -
5. beta-zones of haemolysis
around
them
!!! (2,4)
?

What antigen(s) have the
bacteria
Streptococcus
1.
C
2.
O
3.
M
4.
5.
R
!!! (1,3,4,5)
?

groups

:
1.
C
2.
M
3.
T
4.
R
5.
O
!!! (1)
?

to

the
:
1.
2.
3.
4.

5.
!!! (3)
?

variants

:
1.
C
2.
M
3.
T
4.
R
5.
O
!!! (2)
?

to

with

:
1.
2.
3.
4.

of
1.
2.
3.
4.
5.
Streptococcus genus:
C
O
M
Dividing of haemolytic
streptococci into serological
by Lancefield depends on:
1.
Carbohydrate C
2.
Protein M
3.
Protein T
4.
Protein R
5.
Lipopolysaccharide O
The belonging of streptococci

serogroup by Lancefield's
classification is detected with
help of a reaction:
1.
. Agglutination test
2.
Neutralization test
3.
Precipitation test
4.
5.
Dividing of haemolytic
streptococci into serological
by Griffith depends on:
1.
Carbohydrate C
2.
Protein M
3.
Protein T
4.
Protein R
5.
Lipopolysaccharide O
The belonging of streptococci

serovar by Griffith is detected
the help of a reaction:
1.
Agglutination test
2.
Neutralization test
3.
Precipitation test
4.
5.
5.
!!! (1)
?

:
1.
, .
phagocyto (, M)
2.
3.
4.
5.

!!! (1,2,4)
?

Streptococcus pyogenes:
1.
O
2.
K
3.
S
4.
5.
(,)
!!! (1,3,4,5)
?
Streptococcus
pyogenes:
1.
2.
()
(streptokinase)
3.
()
4.
-
5.
!!! (2,3,4,5)
?

Streptococcus
pneumoniae:
1.
2.
alfa-
3.
4.
5.
sIg A-
!!! (1,2,3,4,5)
?

:
1. Streptococcus pyogenes
fever:
A
2. Streptococcus pyogenes
D
3.
(, )
(erythrogenic,
4.
cell-

pathogenicity of streptococci:
1.
Factors inhibiting
sis (capsule, protein M)
2.
Exotoxins
3.
Endotoxins
4.
Enzymes
5.
All listed above
To name the exotoxins of
1.
Streptolysin O
2.
Streptolysin K
3.
Streptolysin S
4.
Cytotoxins
5.
Pyrogenic (erythrogenic,
scarlatinal) toxin
To name the enzymes of

1.
Catalase
2.
Fibrinolysin
3.
Deoxyribonucleases
(Streptodornase)
4.
RNAase
5.
Hyaluronidase
pathogenicity of Streptococcus
pneumoniae:
1.
Capsule
2.
alfa-haemolysin
3.
Leucocidin
4.
Neuraminidase
5.
sIg A-peptidase
To name the properties of the

infectious agent of scarlet
1. Is Streptococcus pyogenes of
serogroup A
2. Is Streptococcus pyogenes of
serogroup D
3. Produces pyrogenic
scarlatinal) toxin
4. Induces specific humoral and

children
5.
!!! (1,3,4,5)
?
Streptococcus pyogenes
:
1.
-
(,
..)
2.
3.
4.

(, )
complications
5.
,
!!! (1,2,3,4,5)
?

Streptococcus
Streptococcus
pneumoniae:
1.
2.
3.
4.
5.
!!! (1,2,4)
?

which

of
:
1. D
2. 6,5 %
%
3. 40 %
% bile
4. 9-10
5.
!!! (5)
?
Streptococcus
agalactiae,
are
:
1.
?-
B
mediated immune response

5. Provokes infection in
Streptococcus pyogenes are

responsible for appearance of the
following diseases:
1.
Suppurative (pyogenic)
diseases (pharyngitis,
necrotising fascitis, etc.)
2.
Scarlet fever
3.
Endocarditis
4.
Nonsuppurative
(rheumatic fever, acute
glomerulonephritis)
5. Sepsis, including puerperal
one
To name the methods of
infection caused by
pneumoniae:
1. Microscopic
2. Bacteriological
3. Serological
4. Biological
5. Skin-allergic test
To point out property(ies)

is(are) used for identification
enterococci:
1. Belonging to serogroup D by
Lancefield
2. Growth in the presence of 6,5
sodium chloride
3. Growth in the presence of 40
4. Growth at 9-10
5. All listed above
To name the properties of

Streptococcus agalactiae, which
used for its identification:
1.
Is beta-haemolytic
streptococcus of serogroup B
by Lancefield
2.
CAMP-
the
3.
PYR-
(
PYR
)
4.

,
nonsensitive,
5.

!!! (1,2,3,4,5)
?
Streptococcus
pyogenes,
:
1.
beta?-
A
2.
CAMP-
the
3.
PYR-
(
PYR
)
4.

5.

sodium
!!! (1,2,3,4,5)
?

and

Clostridium
1.

rods

rods
2.

rods

rods
3.

shaped

4.

5.

!!! (3)
?
Clostridium
Clostridium

2.
Demonstrates positive
CAMP test
3.
Demonstrates negative
test (pyrrolidonylarylamidase
formation)
4.
Is bacitracin
hydrolyzes sodium hippurate
5.
Often provokes neonatal
meningitis and sepsis
To name the properties of

Streptococcus pyogenes for its
identification:
1.
Is beta-haemolytic
streptococcus of serogroup A
by Lancefield
2.
Demonstrates negative
CAMP test
3.
Demonstrates positive
test (pyrrolidonylarylamidase
formation)
4.
Is bacitracin sensitive
5.
Does not hydrolyze
hippurate

tinctorial properties of genus
Clostridium:
1.
Gram positive nonsporing
2.
Gram negative nonsporing
3.
Gram positive sporing
4.
Gram negative sporing
5.
Gram negative comma-
rods
What species of genus

forms the capsules in human
body?
:
1.
Clostridium tetani
2.
Clostridium septicum
3.
Clostridium novyi
4.
Clostridium perfringens
5.
Clostridium histolyticum
!!! (4)
?
,
which

pure
:
1.
, ,
medium,

2. - ,
, Tarozzi
3. - , agar

(broth),
4. ()
blood, ,
(
and
)
5.

!!! (2,4)
?
Clostridium perfringens

"
"
:
1. 1
2. 3-4
3. 10-12
4. 18-24
5. 3-4
!!! (2)
?

,
which
:
1.
2.
3. -
4. ,
5. ,
!!! (1,3,4,5)
?

1.
2.
3.
4.
5.
Clostridium
Clostridium
Clostridium
Clostridium
Clostridium
tetani
septicum
novyi
perfringens
histolyticum
To name nutrient medium(a),

is(are) used for isolation of
culture of clostridia:
1.
Hiss' media, Endo'
MacConkey' medium
2.
Iron-sulphite agar,
thioglycollate broth, Kittmedium
3. Yolk-salt agar, milk-salt
4.
Shaedler' anaerobe agar
cooked meat Robertson' medium,

sugar agar (Zeissler' medium)
5.
Alkaline nutrient broth
alkaline nutrient agar
Clostridium perfringens forms

sponge-like clot with gas bubbles
in medium, named "milk under oil
layer", after inoculation of
testing material:
1. In 1 hour
2. In 3-4 hours
3. In 10-12 hours
4. In 18-24 hours
5. In 3-4 days
To point out the factors of
pathogenicity of clostridia,
provoke gas anaerobic infection:
1. Exotoxins
2. Endotoxins
3. DNAase
4. Hyaluronidase, proteinases
5. Neuraminidase, fibrinolysin
Toxigenicity of clostridia is
():
2.
3.
4.
in vivo
5.
in vitro
vivo
6.

vitro
!!! (3,4)
?

toxin

with
:
1.

2.

3.

4.

5.

!!! (4)
?
()
biopreparations

infections,
,
:
1.
2.

3.

4.

5.
!!! (2,4)
?
()
biopreparations

,
:
1.
2.

3.

4.

5.
!!! (1)
?
() Clostridium
Clostridium
tetani:
1.
2.
3.
4.
5.

detected with the help of the

reaction(s):
1.
Agglutination test
2.
Precipitation test
3.
Neutralization test in
4.
Neutralization test in
5.

The presence of clostridia
in wound secretions is revealed

detecting:
1.
Haemolytic activity
2.
Coagulase activity
3.
Necrotizing activity
4.
Lecithinase activity
5.
Fibrinolysin activity
What type(s) of
must be used immediately after
trauma for formation of passive
immunity against wound
which are caused by clostridia:
1.
Anatoxin (toxoid)
2.
Antitoxic serum
3.
Live vaccine
4.
5.
Antibiotics
What type(s) of
must be used for formation of
active immunity against wound
infections, which are caused by
clostridia:
1.
Anatoxin (toxoid)
2.
Antitoxic serum
3.
Live vaccine
4.
5.
Antibiotics
To name toxin(s) of
tetani:
1.
2.
3.
4.
5.
Enterotoxin
Tetanospasmin
Tetanolysin
Neuraminidase
All listed above
!!! (2,3)
?
() Clostridium
Clostridium
botulinum:
1.
2.
3.
4.
5.

!!! (4)
?

gas
:
1.
2.
3.
4.
5.
-
!!! (1,2,4)
?
To name toxin(s) of
botulinum:
1.
Enterotoxin
2.
Tetanospasmin
3.
Tetanolysin
4.
Neurotoxins
5.
All listed above
To list the methods of

gangrene:
1.
Microscopic method
2.
Bacteriological method
3.
Serological method
4.
Biological method
5.
Skin-allergic test

:
1.
2.
3.
4.
5.
-
!!! (1,2,3,4)
?

botulism:
1.
Microscopic method
2.
3.
Serological method
4.
Biological method
5.
Skin-allergic test

:
1.
2.
3.
4.
5.
-
!!! (1,2,4)
?

tetanus:
1.
Microscopic method
2.
3.
Serological method
4.
Biological method
5.
Skin-allergic test
(),
()

:
1.
2.
3. -
4.
5.
" "
mount"
" "
To name technique(s) which is

(are) used at microscopic method
of diagnostics of gas gangrene:
1. Staining by Gram
4. Staining by Loeffler
5. Microscopic examination of the
preparations, called the "wetdrop and the "hanging" drop with
the

!!! (1,2,3,5)
?
(),
is(are)
()

:
1.
2.
3. -
4.
5.
mount"
" "
the
" "

!!! (1,2,3,5)
?
(),
is(are)
()

:
1.
2.
3. -
4.
5.
" "
" "

!!! (1,2,3,5)
# ()

tuberculosis
:
1.
Bacillaceae
2.
Mycobacteriaceae
3.
Actinomycetaceae
4.
Enterobacteriaceae
5.
Neisseriaceae
!!! (2)
?

Mycobacterium tuberculosis:
1.
, ,
fast
, -
2.
, ,
acid -
help of the dark field microscopy
To name technique(s) which

used at microscopic method of
diagnostics of botilism:
1. Staining by Gram
preparations, called the "wetdrop and the "hanging" drop with
help of the dark field microscopy
To name technique(s) which

used at microscopic method of
diagnostics of tetanus:
1. Staining by Gram
preparations, called the "wetmount" drop and the "hanging"
drop with the help of the dark
field microscopy
Causative agents of
belong to the family:
1.
Bacillaceae
2.
Mycobacteriaceae
3.
Actinomycetaceae
4.
Enterobacteriaceae
5.
Neisseriaceae
1.
Nonmotile, noncapsulated,
nonsporing Gram positive acidrods
2.
nonsporing Gram positive non
fast rods
, -
sporing
3.
, ,
-
4.
, ,

5.
, ,
-
-
!!! (1)
?

Mycobacterium
tuberculosis:
1.
- (M)
2.
-
3.
4.
-
5.

!!! (2,3,5)
?
Mycobacterium
Mycobacterium
tuberculosis :
1.
24
2.
20
3.
1
4.
14-18
5.
2
!!! (4)
?
Mycobacterium
tuberculosis

of
:
1.
24
2.
2
3.
5
4.
1
5.
2-8
weeks
!!! (5)
?

1.
2.
3.
4.
- (
)
mycolate)
5.
()
3.
Nonmotile, capsulated,
Gram negative rods

4.
Motile, noncapsulated,
nonsporing Gram positive rods
5.
sporing Gram negative acid-fast
rods
To name the culture media for

cultivating of Mycobacterium
tuberculosis:
1.
eat -peptone agar (MP)
2.
Lowenstein-Jensen
3.
Midlebrook
4.
Kitt-Tarozzi
5.
Sauton's synthetic mediu
Generation time of
tuberculosis is:
1.
24 hours
2.
20 minutes
3.
1 hour
4.
14-15 hours
5.
2 weeks
Colonies of Mycobacterium
tuberculosis appear on culture
medium under optimum conditions
cultivating:
1. After incubation for 24 hours
2. After incubation for 2 days
3. After incubation for 5 days
4. After incubation for 1 week
5. After incubation for 2 - 8

pathogenicity of Mycobacterium
tuberculosis:
1.
Capsule
2.
Exotoxin
3.
Endotoxin
4.
Cord factor (trehalose
5.
Sulfolipids (sulfatides)
!!! (4,5)
?
Mycobacterium tuberculosis

:
1.

intracellular

2.
-
3.
-
4.
()
aerobic
5.
()
anaerobic
!!! (1,2,4)
?
Mycobacterium tuberculosis is
characterized by the following
properties:
1.
Is facultative
pathogen
2.
Is acid-fast
3.
Is non acid-fast
4.
Is strict (obligate)
microorganism
5.
Is strict (obligate)
microorganism

:
1.

2.

investigation
3.

4.

5.
- (
test of

)
!!! (1,2,3,4,5)
?

tuberculosis diagnostics:
1.
Microscopic examination
2.
Bacteriological
-
Mycobacterium tuberculosis
:
1.

2.

3.
(
microcultures
)
4.

5.

!!! (3)
?
The presence of cord factor of

Mycobacterium tuberculosis is
revealed with the help of:
1.
Agglutination test
2.
Montoux test
3.
The method of
3.
4.
5.
Biological method
Serological method
Skin-allergy test (skin
delayed hypersensitivity type)
(Price's method)
4.
Homogenization technique
5.
Floatation method

can
:
1.

2.

with
3.

4.

5.

The negative Montoux test

testify about:
1.
Presence of delayed
hypersensitivity to
tuberculoprotein
2.
Result of immunization
vaccine BCG
3.
Absence of delayed
hypersensitivity to
tuberculoprotein
4.
Development of active
tuberculosis
5.
Absence of tuberculosis
!!! (3,5)
?

can
:
1.

2.

with
3.

4.

5.

The positive Montoux test

testify about:
1.
Presence of delayed
hypersensitivity to
tuberculoprotein
2.
Result of immunization
vaccine BCG
3.
Absence of delayed
hypersensitivity to
tuberculoprotein
4.
Development of active
tuberculosis
5.
Absence of tuberculosis
!!! (1,2,4)
?

:
1.

vaccine
2.
()
vaccin
3.
4.
-
5.
!!! (1)
?

:
e
1.

2.

contaminated
()
3.
-
infectious
4.

5.

BCG vaccine for tuberculosis

prophylaxis is:
1.
2.
Inactivated (killed)
3.
4.
Toxoid (anatoxin)
Genetically engineering
5.
Allergen
To point out the ways of

transmission of tuberculosis:
1.
2.
By direct contact
By ingestion of
meal (milk)
3.
By inhalation of an
aerosol (through coughing)
4.
By sexual transmission
5.
By bite of insects
!!! (2,3)
?

:
Runyon's
1.
2.
3.
4.
To list the groups of

mycobacteria according to
classification:
1.
Photochromogens
2.
Scotochromogens
3.
Nonphotochromogens
5.
4.
5.
Haemolytic
Rapid growers
!!! (1,2,3,5)
?

:
1.
2.
3.
4.
5.
!!! (2,3,4,5)
?

:
1.

2.
3.
4.
5.
!!! (1,2,3,4,5)
?
-
:
1.

2.
-
3.
-
4.

5.

!!! (2)
?

Corynebacterium diphtheriae:
1., ,nonspo, ,-
2., ,acid ,at
, ,

3., , ,,
,

4.
, ,

-
To list antibiotics using for

treatment of tuberculosis:
1.
Tetracycline
2.
Kanamycin
3.
Rifampicin
4.
Cycloserine
5.
Streptomycin
To list antituberculous drugs

using for treatment of a
tuberculosis:
1.
Paraaminosalycylic acid
2.
Isoniazid
3.
Ethambutol
4.
Ethionamide
5.
Pyrazinamide
Differentiation of acid-fast
and non acid-fast bacteria is
carried out with the help of:
1.
Gram's technique
2.
Ziehl-Neelsen's method
3.
Burry-Gins's technique
4.
Neisser's technique
5.
Loeffler's method
1.Nonmotile, noncapsulated,
ring Gram positive acid-fast rods
2. Nonmotile, noncapsulated,
nonsporing, club-shaped, non
fast Gram positive rods arranged
various angles to each other
3. Nonmotile, capsulated, sporing
club-shaped, non acid-fast, Gram
negative rods arranged at various
angles to each other
4.Motile, noncapsulated,
nonsporing comma-shaped Gram
negative rods
5.
sporing Gram negative acid-fast
rods
5. , ,, -,
!!! (3)
?

of
Corynebacterium
1.

2.
s
Ernst
3.

(
granule
)
4.

r
( )
poles
5.

( )
cente
!!! (1,2,3,4)
?

Corynebacterium diphtheriae

:
1.
2.
-
3.
-
4.
5.
!!! (4,5)
?
Corynebacterium
diphtheriae :
1.
2.
3.
4.
5.
(,
, )
!!! (2,3,5)
?

is
:
1.

granul
2.

To point out the properties

volutin granules of
diphtheriae:
1.
Their chemical nature is
polymetaphosphates
2.
They are named Babes-
granules (bodies)
3.
They are metachromatic
(after staining with Loeffler's
methylene blue)
4.
They are situated at the
of the bacilli (polar bodies)

5.
They are situated in the
of the bacilli (central bodies)
The presence of volutin

granules of Corynebacterium
diphtheriae are revealed with the
help of:
1.
Gram's technique
2.
Ziehl-Neelsen's method
3.
Burry-Gins's technique
4.
Neisser's technique
5.
Loeffler's method
Pathogenicity of
Corynebacterium diphtheriae is
caused with the presence of:
1.
Flagella
2.
Fimbriae
3.
Exotoxin
4.
Endotoxin
5.
Enzymes (hyaluronidase,
neuraminidase, fibrinolysin)
Diphtheria toxin production
connected with:
1. The presence of volutin
2.
Fimbriae formation
3.
() 3.
4.

4.
5.

5.
!!! (3)
?

1.
Classical
2.
Mitis
3.
Intermedius
4.
El-Tor
5.
Gravis
Lysogenic (phage) conversion

The presence of endotoxin
The presence of microcapsule
To name the subspecies of

1.
Classical
2.
Mitis
3.
Intermedius
4.
El-Tor
5.
Gravis
!!! (2,3,5)
?

gravis
of
1.(+), (+),(+),
(+),(+)
Urease(+)
2.(+), (-),(-),
(+), (-)
Urease(-)
3.(-), (-),(-),
(-), (-)
Urease(-)
4.(+),(-), (+),
(+),(-)
Urease(-)
5.(+/-),(+/-),Sucrose(+/-),
(-), (-), (+)
Urease(+)
!!! (4)
?

mitis
1.
(+), (+),
(+), (+),
Urease(+)
(+)
2.
(+), (-),
Urease(-)
(-), (+),
(-)
Urease(-)
3.
(-), (-),
(-), (-), (Urease(-)
)
Sucrose(+/-),
4.
+),(-),
Urease(+)
(+), (+),(-)
To list the biochemical

properties of subspecies gravis
1.
Glucose(+), Sucrose(+),
Starch(+), Cystinase(+),
2.
Glucose(+), Sucrose(-),
Starch(-), Cystinase(+),
3.
Glucose(-), Sucrose(-),
Starch(-), Cystinase(-),
4.
5.
Glucose(+/-),

properties of subspecies mitis of
1.
2.
3.
4.
5.
Glucose(+/-),
5.
(+/-),(+/-),
(-), (-),
(+)
!!! (2)
?

:
1.
(+), (+),
(+), (+),
(+)
Urease(+)
2.
(+), (-),
(-), (+),
Urease(-)
(-)
)
3.
(-), (-),
Urease(-)
)
(-), (-), (o
)
Urease(-)
f
4.
+),(-),
Sucrose(+/-),
(+), (+),(-)
Urease(+)
5.
(+/-),(+/-),
(-), (-),
(+)
!!! (5)
?

gravis Corynebacterium
diphtheriae:
1.
(3-5 )
2.
(1-2 )
(3-5 mm)
3.
-
(1-2 mm)
colour
4.

5.
S- (
coloni
)
and
6.
R- (

with
)
!!! (1,3,6)
?

mitis Corynebacterium
mitis
diphtheriae:
t

properties of non-pathogenic
corynebacteria (false diphtheria
bacteria):
1.
2.
3.
4.
5.
Glucose(+/-),
To point out the cultural

characteristics of subspecies
gravis of Corynebacterium
diphtheriae:
1.
Large size of colonies
2.
Small size of colonies
3.
Black or greyish-black
colonies
4.
Grey or brown colour of
5.
S-form (smooth surface
entire margin)
6.
R-form (rough surface
radial lines and wavy margin)
To point out the cultural

characteristics of subspecies
of Corynebacterium diphtheriae:
1.
(3-5 )
(3-5 mm o
2.
(1-2 )
(1-2 mm
3.
-
colour
4.

coloni
5.
S- (
and
)
6.
R- (
with

)
!!! (2,3,5)
?

:
1.

immunity

2.

immunity

3.

4.

5.

!!! (1)
?
Corynebacterium
Corynebacterium
diphtheriae :
1.

2.

3.

4.

5.

1.
Large size of colonies
2.
Small size of colonies
3.
Black or greyish-black
colonies
4.
Grey or brown colour of
5.
S-form (smooth surface
entire margin)
6.
R-form (rough surface
radial lines and wavy margin)
Positive Schick's test

testifies about:
1.
Absence of antitoxic
diphtheria
2.
Presence of antitoxic
to diphtheria
3.
Absence of antimicrobial
immunity to diphtheria
4.
Presence of antimicrobial
immunity to diphtheria
5.
Presence of delayed
hypersensitivity to diphtheria
toxin
Toxigenicity of
diphtheriae is detected with the
help of:
1.
Ascoli's test
2.
Schick's test
3.
Agglutination test
4.
Precipitation test
5.
!!! (4)
?
(),
() ()
treatment
:
1.
2.

3.
4.
5.
DPT
!!! (2,3,4)
?
To name the remedy(ies) which

is(are) administered for
of diphtheria:
1.
Toxoid (anatoxin)
2.
Antitoxic serum
3.
Penicillin G
4.
Erythromycin
5.
DPT vaccine

:
1.
2.
3.
4.
5.
!!! (1,3,4)
?
Diphtheria toxoid (anatoxin)

provides formation of immunity in
human organism with following
characteristic(s):
1.
Active
2.
Passive
3.
Acquired
4.
Antitoxic
5.
Antimicrobial
(),
() ()
:
1.
f
2.

3.
4.
5.
DPT
!!! (1,5)
?

is(are) used for prophylaxis of
diphtheria:
1.
Toxoid (anatoxin)

r
:
1.
2.
investigation
3.
4.
5. - (
o

)
!!! (1,2,3,4)
?

:
1.

cellul

accumulation
,
consequently
,

2.
junctions

3.

spinal

of
4. ,

2.
3.
4.
5.
Antitoxic serum
Penicillin G
Erythromycin
DPT vaccine

diphtheria diagnostics:
1.
Microscopic examination
2.
Bacteriological
3.
4.
5.
Biological method
Serological method
Skin-allergy test (skin test
To point out mechanism of

action of diphtheria exotoxin:
1. Prolonged activation of
adenylate cyclase and
of high cAMP level and
active efflux of ions and water
into the small intestine lumen
2.Acts on the myoneuronal
blocking release of acetylcholine
3. Blocks release of inhibitory
mediators in synapses of the
cord and causes the rigid spasm
muscles
4.Toxins are enzymes, which
provoke
(, C),
membra

C),
(-, ), ..
5.
(
, ADP

2 (EF-2)
2(EF-2)
!!! (5)
?

:
1.

cellul

accumulation
,
consequently
,

lumen
2. ,

3.

media
cord
4. ,
muscles

provoke
(-,
C),
toxin,phospholipase C)
(,
-), ..
5.

synthesi
(
ADP
,
(EF-2)
2 (EF-2)
!!! (3)
?

Clostridium perfringens:
1.

cellul
,
the destroying
of eukaryotic
nes (alpha toxin, phospholipase

demonstrate proteolytic action
(lambda, kappa toxins), etc.
5.Inhibition of protein synthesi
in human cells (due to toxin is
ribosyl transferase which binds
eukaryotic elongation factor

ac ion of botulinum exotoxin:
1.
Prolonged activation of
causes active efflux of ions and
water into the small intestine
2.
Acts on the myoneuronal
junctions, blocking release of
acetylcholine
3.Blocks release of inhibitory
tors in synapses of the spinal
and causes the rigid spasm of
the destroying of eukaryotic
membranes(alpha
5.
Inhibition of protein
eukaryotic elongation factor 2

action of Clostridium perfringens
exotoxin:
1.
Prolonged activation of
accumulation
,
consequently

2. ,
lumen

junctions
3.

spinal
4.
,
of

(-,
provoke
C),
membra (,
C),
), ..
5.

(
synthesis
,
ADP
2 (F-2)
2(EF-2)
!!! (4)
?

:
1.

cellular

accumulation
,
consequently
,

2. ,

junctions,
3.

me
cord
4. ,
muscles

provoke
(-,
membranes
C),
demonst (-,

2. Acts on the myoneuronal
mediators in synapses of the
cord and causes the rigid spasm
muscles
4. Toxins are enzymes, which
the destroying
of eukaryotic
nes (alpha toxin,phospholipase


action of cholera exotoxin:
1. Prolonged activation of
lumen
2. Acts on the myoneuronal
diators in synapses of the spinal
the destroying
of eukaryotic
(alpha toxin,phospholipase C),

rate proteolytic action (lambda,
kappa
- ), ..
5.
(
ADP
,

2(EF-2)
2 (EF-2)
!!! (1)
?

:
1.
cellular

accumulation
,
consequently
,

lumen
2. ,
junctions,

3.
media
cord

muscles
4. ,
provoke

membranes
(?-,
C),
(?-, ?), ..
in
5.
(
, 2(EF-2)

2 (EF-2)
!!! (3)
?

Neisseria
Neisseria
meningitidis:
1. ,
with
, ,

2. ,
chains,
toxins), etc.
5.Inhibition of protein synthesis

action of tetanus exotoxin:
1.Prolonged activation of
2.Acts on the myoneuronal
3.Blocks release of inhibitory
tors in synapses of the spinal
the destroying
of eukaryotic
(alpha toxin,phospholipase C),

5.Inhibition of protein synthesis
human cells (due to toxin is ADP

meningitidis:
1.
2.
, ,
with
3. ,
, ,

(diplococci,
4. ,
,
, (,
in
" ")
with
5. , ,
,
(),
!!! (4)
?
Neisseria meningitidis
:
1.

2.

3.

4.

5.

!!! (3)
?
Neisseria
meningitidis
:
1.
2.
3.
4.

5.
haemagglutination
!!! (3)
?
()
(),
Neisseria
Neisseria
meningitidis:
1.
MA, M
2.

3.
-
4.

5.
-
!!! (2,4)
?
ferments
():
1.
2.
which are able to have capsules

3.
4.
capsulated, nonmotile bean-shaped
cocci arranged in pairs
they resemble "coffee beans")
5.
pairs (diplococci) surrounded
capsules
Species of Neisseria
meningitidis is divided into
serogroups according to:
1.
Antigens of flagella
2.
Antigens of fimbriae
3.
Antigens of capsule
4.
Antigens of cell wall
5.
Ribosome's antigens
Detection of serotypes of
Neisseria meningitidis is carried
out with the help of reaction:
1.
Precipitation test
2.
Neutralization test
3.
Agglutination test
4.
5.
Reaction of
To name the culture medium(a)

which are acceptable for
meningitidis cultivating:
1.
MPA, MPB
2.
Serum agar
3.
Yolk-salt agar
4.
Blood agar
5.
Kitt-Tarozzi
till acid the carbohydrate(s):
1.
glucose
2.
lactose
3.
4.
5.
!!! (1,3)
?

Neisseria meningitidis:
meningitidis:
1.
2.
3.
IgA-
4.
5.
!!! (1,2,3,4,5)
?

meningitidis:
1.
2.
()
3.
4.
5.
IgA-
!!! (1,2,3,5)
?

, Neisseria
caused
meningitidis:
1.
2.
3.
4.
5.

!!! (2,3,4)
?

, Neisseria
by
meningitidis:
1.
2.
3.
4.
5. - (
of

)
!!! (1,2,3,4)
?
(),
() ()
treatment
,
1.
2.
3.
4. ( )
3.
4.
5.
maltose
mannitol
sucrose
To list the pathogenicity

factors of Neisseria
1.
2.
3.
4.
5.
Neuraminidase
Hyaluronidase
IgA-protease
Endotoxin
Capsule
To list the pathogenicity

factors of Neisseria
1.
2.
3.
4.
5.
Capsule
Pili (fimbriae)
Endotoxin
Exotoxin
IgA-protease
To name the clinical

manifestations of infection
by Neisseria meningitidis:
1.
Urethritis
2.
Nasopharyngitis
3.
Sepsis
4.
Meningitis
5.
All mentioned above
diagnostics of infections caused
1. Microscopic examination
2. Bacteriological investigation
3. Biological method
4. Serological method
5. Skin-allergy test (skin test

is(are) administered for
of infections caused by Neisseria
meningitidis:
1.
Penicillin G
2.
Chephalosporins
3.
Chloramphenicol
4.
Rifampin (for sanation of
5.
!!! (5)
?
,
are
,
infections
1.

(
noncapsulated
)
2.
()
vaccine
vaccine
3.

polysaccharides
(
A,C,W Y)
4.

5.

!!! (3)
?

Bordetella
Bordetella
pertussis:
1. ,
, ,

2. ,
chains,
,
,
ovoid
3. ,
,
,
(diplococ4. ,
,
nonsporing,nonmotile
, (,
" ")
capsules
5. , ,
,
(),
!!! (3)
?
()
(),
Bordetella
carriers)
5.
All listed above
To name the measures which
caused by Neisseria meningitidis:
1.
(containing spores of
strain of bacteria)
2.
Inactivated (killed)
3.
Subunit polyvalent
(containing capsular
of serogroups A,C,W and Y)
4.
Control of fleas
5.
Control of rodents

pertussis:
1.Gram positive nonsporing, with
which are able to have capsules
nonmotile, capsulated small
coccobacilli arranged singly
capsulated, nonmotile bean-shaped
cocci arranged in pairs
ci, they resemble "coffee beans")
5.Gram positive
"lancet-shaped" cocci in pairs
(diplococci) surrounded with
To name the culture medium(a)

which are acceptable for
Bordetella
pertussis:
1.
-
2.
-
potato3.
- (- )
4.
-
5.
-
!!! (3,5)
pertussis cultivating:
1.
Kitt-Tarozzi
2.
Lowenstein-Jensen
3.
Bordet-Gengou (bloodglycerol agar)
4.
Yolk-salt agar
5.
Casein-charcoal agar

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The focal distance of the immersion objective is:

Gram-negative microorganisms are:

What media are classified as

Hiss' media belong to:

What media is used for

On yolk-salt agar can grow:

Isolation of pure culture of

The disposable plastic

The control of the sterility

5. Realization of all the listed

The period of generation of

The proteolytic properties of

The formation of indol

The formation of hydrogen

To give the definition of the

To give the definition of the

To give the definition of the

Quantity of coliform bacteria

Coliform bacteria - titer

Minimal volume of water, in

The detection of coliform

At the sanitaryexamination of soil are defined:

What changes of structure of

genera Proteus, Candida and etc.

To point out the term meaning

To point out the mechanism of

To point out the mechanism of

Point out antimicrobial

To point out the mechanism of

To point out the mechanism of

Point out the mechanisms of

Point out the drugs, which

caused by pathogenic Mycoplasmas:

Name the form of symbiosis,

Name the form of symbiosis,

of the other population:

Innate cell-mediated immunity

Innate humoral immunity is

The factors of innate immunity

Name the kind of immunity

Bacterial cells can have the

Local immunity of the mucous

To select the best

The agglutination reactions

To name the type of serum,

Erytrocytic diagnosticums are

To name kind(s) of the

All listed above

To point out variant(s) of

Schick's and Dick's

Complement takes part in

Antitoxic sera are used in

To point out the kind(s) of

with labeled antibodies:

Antiglobulin sera to human

Immunofluorescent test is used

Labeled antiglobulin sera are

Haemolytic system consists of:

According to the mechanism

The followig reaction(s)

To point out the types of

In medical practice immune