Sleep Disorders in cohort of CKD Patients on Maintenance hemodialysis and CAPD

Aims and objectives of the study

1.To assess the prevalence of sleep disorders including sleep disordered breathing in CKD patients on maintenance h
2.To correlate the predictability of questionnaire based results with clinical findings and polysomnography.

3.To assess the impact of dialysis modalit of renal replacement (HD VS CAPD ) on nature and severity of sleep disor

CKD patients on maintenance haemodialysis (MHD) or continuous ambulatory peritoneal dialysis (CAPD) by validated self-adm

nd polysomnography.

ature and severity of sleep disorders of breathing employing polysomonography.

s (CAPD) by validated self-administered questionnaire.

NAME

AGE\SEX MRD NO OCCUPATION

NKD

RRT/DURATION

DETAILS

PET TEST

Prabhakar
Sampath Raj
Varghese
PSB Murthy
Sathiah
Antony
Armugana
Nagabhushan
Mehamood
Farooq
Lourde swamy
Manniyammal
Krishne Gowda
Ramesh T
Raghavendra
Dr.Tulusa Halur
Indiramma
Renuka
D Sundari
Srinivas
Kotramma
Muniyelappa
Vasanthamma
Gopalkrishna
Haleem Khan
Chikkabyre Gowda
Mahadevan
Mr.Stbastin
Mosses
Mr.Rajendra

45/M
58/M
66/M
67/M
60/M
53/M
50/M
54/M
45/M
47/M
40/M
72/F
35/M
35/M
63/M
50/F
67/M
45/F
65/F
56/M
63/F
45/M
45/F
58/M
58/M
65/M
60/M
58/F
33/m
65/M

Crescentric GN
HT Nephrosclerosis
DN
NK
DN
NK
CGN
CGN
NK
DN
CGN
NK
NK
NK
DN
CIN
HT Nephrosclerosis
DN
DN
DN
NK
DN
ADPKD
DN
DN
DN
DN
CIN
DN
NK

HD/4 Years
CAPD/2 Years
CAPD/6 Years
CAPD/1 Years
CAPD/1 Year
HD/1 Year
HD/1 Year
HD/1 Year
CAPD/8 Months
CAPD/3 Years
HD/5 Years
HD/3 Years
HD/2 Years
HD/1 Year
CAPD/3 Years
CAPD/2 Years
HD/1 Year
HD 1 Year
CAPD 1 Year
HD 1 Year
CAPD 1 Year
HD/2 Years
HD/1 Year
CAPD 4 Years
HD/5 Years
HD/1 Year
HD 6 Years
CAPD/2 Years
HD/5 Years
HD/2 Years

2/WK, Early Morning

2.5*2, 7.5*1 UF 1.5L
2.5*2, 1.5*1 UF
1.5*2, 2.5*1 UF 600 ml
2.5*1, 1.5*2 UF 1.5L
3/WK Early Morning
3/WK Afternoon
3/WK Evening
1.5*3, UF 2.5L
2.5*2, 7.5*1 UF 1.8L
3/WK Afternoon
3/WK Afternoon
2/WK, Early Morning
2/WK, Afternoon
2.5*2, 1.5*1 UF
1.5*1,2.5*2, UF 1.2L
2/WK, Early Morning
2/WK, Early Morning
2.5*2, 1.5*1 UF
2/WK, Early Morning
2.5*2, 1.5*1 UF
3/WK Afternoon
2/WK Early Morning
1.5*3,UF 800 ml
3/WK Afternoon
2/WK, Afternoon
3/WK, Early Morning
2.5*2, 1.5*1 UF
3/WK Afternoon
3/WK, Early Morning

Not Applicable
High Average
Not Known
High Average
High Average
Not Applicable
Not Applicable
Not Applicable
Not Known
High Average
Not Applicable
Not Applicable
Not Applicable
Not Applicable
low average
Low Average
Not Applicable
Not Applicable
High Average
Not Applicable
High Average
Not Applicable
Not Applicable
High Average
Not Applicable
Not Applicable
Not Applicable
Low Average
Not Applicable
Not Applicable

2188763
1579199
1598257
2098855
2021623
1643002
2665621
2631619
1867525
2258101
2284572
2143550
2366133
2313376
1596657
2059086
2602873
2624241
2623500
2522051
2051638
1928876
1172153
2338095
2090501
2098765
1766751
2713686
2134538
2484297

Clerk
KEB Mechanic
Rtd
Proffessor
KEB Mechanic
Police Constable
Clerk
Rly Mechanic
Police Constable
Clerk
Technician
House Wife
Teacher
Clerk
Rtd Engineer
Doctor
House Wife
House Wife
House Wife
Teacher
House Wife
Driver
House Wife
ITI engineer rtd
Clerk
Rtd Engineer
Rtd Engineer
House Wife
Teacher
CA

Abbreviations
NKD
NK
DN
CGN
HT
ADPKD
CIN
HD
CAPD
WK
UF
EDS
ESS
PSQ INDEX
BSQ
DM
CAD
SVD
EPO
BMI
NCS
HB
TC/DC
PC
BU/S.CR
TP/ALB
ALP/GGT
TSAT
RDI
ODI
PLM

Native kidney disease

Not Known
Diabetic Nephropathi
Chronic Glomerulo Nephritis
Hypertension
Autosomal dominant polycytic disease
chronic interstetial nephritis
hemodialysis
chronic peritoneal dialysis
week
ultrafiltration
excessive day time sleepiness
The Epworth Sleepiness Scale key
Pittsburg sleep quality index
Berlin Questionnaire
diabetis mallitus
coronary artery disease
single vessel disease
erythropoitin
body mass indes
neck circumferance
hemoglobin
total and differential count
platelet count
blood urea/serum creatinine
total protein/albumin
alkaline phosphatase/gama glutamile transferase
transferrin saturation
Respiratory Disturbance index
Oxygen desaturation index
Periodic limb moments

TSD
AHI
RRT
CA/PO4
UA
RBS
ECG
PET

total sleep duration

Apnoea / hypoapnea index

Renal Replacement Therapy
Calcium/Posphorus
Uric acid
Random blood sugars
Electro cardiogram
Peritoneal equilibration test

Snoring/Years
2
2
6
4
15
5
4
3
0
5
6
2
3
1
6
3
3
1
1
1
2
4
5
2
4
1
1
2
2
0

HISTORY
Apnoea/Years
2
2
3
4
15
5
5
4
2
5
6
0
3
0
6
3
2
2
2
2
0
4
5
2
2
2
2
1
2
2

ESS SCALE
PSQ INDEX

BSQ

Nocturia/Years
2
2
3
0
5
3
3
4
5
5
0
0
0
0
6
6
0
4
2
2
0
6
6
0
0
4
0
6
0
5

NORMAL
NORMAL
NORMAL
NORMAL
EDS
NORMAL
EDS
EDS
NORMAL
EDS
EDS
NORMAL
EDS
EDS
EDS
EDS
NORMAL
NORMAL
EDS
NORMAL
NORMAL
EDS
EDS
NORMAL
EDS
NORMAL
NORMAL
NORMAL
NORMAL
NORMAL

10
12
8
13
12
19
20
15
17
13
11
6
10
14
15
16
15
4
12
14
14
18
8
10
15
8
10
8
11
8

HR
HR
HR
HR
HR
LR
HR
HR
LR
LR
HR
LR
HR
LR
HR
HR
LR
LR
HR
LR
LR
HR
HR
LR
HR
LR
HR
LR
LR
LR

DM/Years HT/Years
4
4
10
5
20
10
0
5
5
20
10
7
0
6
0
5
0
10
5
4
0
6
0
10
0
8
0
6
20
10
0
10
0
6
10
6
5
5
14
6
6
6
8
4
0
6
4
4
6
6
6
6
8
5
0
7
6
6
0
10

HYPERLIPEDEMIA
YES
YES
NO
NO
NO
NO
YES
NO
NO
YES
NO
NO
YES
YES
NO
NO
NO
NO
NO
NO
NO
YES
NO
YES
NO
NO
NO
NO
NO
NO

COMORBIDITIES
STROKE
NO
NO
NO
NO
NO
NO
NO
NO
NO
YES 2 Years back Rt.MCA infarct
NO
NO
NO
NO
NO
NO
NO
NO
NO
NO
NO
NO
NO
RT.MCA infarct 3 Years back
NO
NO
NO
NO
NO
NO

COFFEE TEAHYPNOTICS EPO

CARDICAC DISEASE
NO
NO
CAD
CAD
CAD
NO
NO
CAD-SVD
NO
NO
CAD
NO
NO
NO
CAD
NO
NO
CAD
NO
CAD
NO
CAD
NO
CAD
CAD-TVD, S/P PTCA
CAD
NO
NO
CAD
NO
35.29411765

YES
YES
YES
NO
YES
YES
YES
YES
YES
YES
YES
YES
NO
NO
NO
YES
NO
YES
YES
YES
NO
YES
YES
YES
YES
YES
YES
YES
YES
YES

NO
NO
NO
NO
YES
NO
NO
NO
YES
NO
NO
NO
NO
NO
NO
NO
NO
YES
YES
NO
NO
NO
NO
NO
NO
NO
NO
NO
NO
YES

2/WK 4 Years
2/WK 4 Years
2/WK 4 Years
2/WK 5 Years
2/WK 1 Year
3/WK
2/WK
2/WK
2/WK
ONCE/WK
2/WK
2/WK
NO
2/WK
2/WK 3 Years
ONCE/WK
NO
3/WK
NO
2/WK
NO
3/WK 1 Year
3/WK
3/WK
3/WK
2/WK
3/WK
ONCE/WK
3/WK
2/WK

VITAMIN DHEIGHT cms

YES 4 Years
YES 3 Years
YES 6 Years
4 Years
3 Years
2 Years
2 Years
1 Year
YES
YES
YES
YES
NO
YES
YES
YES
NO
YES
NO
YES
NO
YES
YES
NO
YES
YES
YES
YES
YES
YES

175
174
157
164
160
167
163
152
167
171
165
143
165
145
158
160
144
165
145
168
144
164
144
163
169
147
169
160
170
167

WEIGHT kg BMI
88
94
52
54
53
65
62
59
64
67
69
44
75
55
54
72
51
77
78
58
75
77
51
56
58
50
62
72
60
64

28.73
31
22
18.9
20.7
23.3
23.33
23.33
22.94
22.91
25.3
21.56
27.54
26.15
21.63
28.12
24.9
28.28
37.09
20.54
36.16
28.62
24.9
21.07
20.3
23.1
21.7
28.12
20.75
22.94

HIP/WAIST RATIO NCS cms

1.4
0.95
1.02
1.02
1.04
1
1
0.95
0.94
1.04
1.02
1.04
1.02
1.09
1.02
1.1
1.2
1.02
1.4
1
1.4
1.13
1.01
1.02
1.02
1.04
1.05
1.1
1.02
1.03

18
14
16
13
14
14
14
16
16
16
16
13
15
16
16
16
13
18
18
16
18
15
14
14
16
15
15
16
16
15

HB%
7.6
10.2
12.3
8.2
15
8.4
6.4
6.7
7.3
11.2
10.5
11.9
4.7
9
12.3
9.1
13.1
8.9
9.3
8.4
10.2
9.5
8.7
9.3
8.9
9.1
11.8
8.1
8
8.3

20.75882353

TC\DC
PC Lakh RBS BU/S.CR
4402 70/23
2.3 123 47/7.3
12403 79/20
2.7 230 83/9.0
4201 76/23
2.8 239 94/9.3
4905 85/15
2 115 78/5.3
4201 73/27
1.5 115 116/9.4
5300 63/28
3 243 158/7.8
6702 72/25
4 103 143/10.6
6303 77/27
2 145 142/8.2
7202 71/28
3.3 300 100/6
7402 62/37
2.2 300 200/11
6412 71/26
2.24 120 198/9.8
10.900 78/15
2.48 93 87/5.5
5600 70/20
3 90 350/22.7
5786 68/24
2.4 234 99/9
6802 71/18
2.3 188 100/10
5800 75/16
2.2 73 78/10.2
5700 78/14
2 122 90/8.3
5800 75/16
1.56 300 109/7.6
6802 71/18
2.3 243 190/9.1
5200 60/14
1.2 240 99/7.3
10700 77/20
2 140 196/8.3
6802 71/18
2.3 224 64/7
5300 60/39
1.2 101 134/7
6802 71/18
2 243 142/8.2
6802 71/18
3 240 191/9.0
5800 75/16
2.2 73 178/10.2
6802 71/18
1.4 230 100/12.7
6800 75/16
2.2 173 178/10.2
6802 81/10
3.4 240 191/9.0
7202 71/28
2.9 300 120/7.3

BIOCHEMISTRY
SE
CA PO4 CA*PO4 UA
136/5.2 8.9 5.3
47.17
5
146/4.8
8 4.2
33.6 5.6
142.4.3 8.2 3.4
27.88 5.4
139/4.4 7.6 4.2
37.24 2.6
114/5.3 8.1 4.7
38.07 4.3
141/4.1 8.5 4.3
36.55
5
134/4.3
8 3.7
29.6 5.4
138/5.2 7.6 4.1
31.16 4.3
139/4.5 8.3
3
24.9 2.3
131/3.8
7 3.5
24.5 7.3
141/4
8.3 6.4
53.12
6
136/4
8.3 6.5
54 6.2
134/4.8 5.8 11
63.8 10.3
145/4.3 8.5 6.4
55.25 7.6
142/4.9
9
4
36 5.4
148/3.8 8.5 7.3
62.05 7.3
148/3.8 8.9 3.6
32.04 7.4
126/4.6 6.9
3
20.7
8
130/3.8 7.8 5.4
42.12 6.8
136/4
6.1 5.7
44.53 10.1
132/4.2 8.6 5.7
42.42 6.5
140/4.3
9 4.1
36.9 6.3
148/3.8
8 2.6
20.8 6.7
141/4
8.2 3.4
27.88 5.7
130/3.8 8.2 2.1
17.22
5
148/3.8 8.8
7
61.6 7.3
141/5.0 9.6 3.3
31.68
3
148/3.8 8.5 7.3
62.05
7
130/3.8 8.9
4
35.6
5
139/4.5
9
3
27
4

TP/ALB
6.3/3.2
6.6/3.1
6.8/2.8
6.8/2.3
6.8/3.5
6.4/3.3
6.3/3.4
7.4/3.4
6.9/3.1
6.6/2.6
6.3/2.4
6.4/2.5
6/2.9
6.5/2.3
7/3.2
5.3/2.9
6.1/3.8
5.3/2.3
5/2.1
6.2/1.8
7.4/3.4
7.2/3.9
5.5/2.7
6.3/3.0
6.0/2.3
5.3/2.0
7.6/2.0
5.3/2.9
6.0/2.7
6.9/3.1

TB/DB
0.3/0.4
0.2/0.3
0.4/0.2
0.3/0.4
0.3/0.4
0.3/0.2
0.4/0.3
0.3/0.4
0,5/0.6
0.3/0.4
0.2/0.1
0.3/01
0.3/01
0.3/0.4
0.3/01
0.3/01
0.2/0.1
0.5/0.3
0.3/0.1
0.2/0.1
0.7/0.2
0.3/01
0.9/0.3
0.4/0.3
0.5/0.3
0.3/01
0.3/0.2
0.3/01
0.5/0.3
0.5/0.6

AST/ALT
32/34
17/23
19/28
19/28
13/23
14/13
14/13
16/24
13/24
13/24
23/24
35/30
45/49
23/32
20/25
17/23
16/30
37/17
29/36
30/28
15/25
10/27
34/39
23/24
47/42
17/23
20/23
217/23
41/32
34/34

ALP/GGT
124/123
120/26
134/56
151/19
154/34
151/19
151/19
357/39
315/114
478/22
128/48
97/34
125/33
98/43
136/39
55/21
55/25
81/30
97/49
137/78
87/25
97/40
159/99
97/34
169/72
155/21
158/53
155/21
169/72
315/114

LIPIDS(CHO/HDL/LDL/TG
TSAT % FERRITIN
214/23/128/32
12.8
763
250/20/128/34
13
700
123/28/43/33
27
350
124/28/50/35
6
42
115/22/26/103
30
352
250/36/41/100
27
122
250/36/131/62
88
500
104/37/47/81
48
266
161/41/93/66
18
160
272/28/120/200
23
222
115/22/26/103
15
20
119/29/20/111
20
210
272/27/113/193
87.4
608
132/54/111/123
23%
322
128/23/43/33
23
270
115/22/26/103
30
500
161/41/93/66
20
175
172/48/98/86
15
20
115/22/26/103
35
616
138/23/43/344
37
617
140/42/53/130
16
22
220/26/129/341
15
230
115/22/26/103
11
326
272/27/113/193
20
210
140/42/53/130
25
185
115/122/26/103
21
181
158/49/80/68
21
124
115/22/26/103
25
432
147/62/63/132
25
185
165/41/88/76
20
180

ECHO CARDIOGRAPHY
EF 60%, NORMAL
EF 65%, Concentric LVH
EF 45%, RWMA
EF 20%, RWMA Dilated Chambers
EF 40%, Concentric LVH, LVDD Dialated Chambers
EF 54%, Concentric LVH, LVDD DIL LA/LV
EF 64%, LVDD
EF 40 %, Global Hypokinesia, RWMA
EF 60%, Normal
EF 40%, Concentric LVH, RWMA, LVDD
EF 45%, Concentric LVH
EF 60%, Concentric LVH, RWMA
EF 62%, Concentric LVH
EF 40%,LVDD,RWMA
EF 45%, Concentric LVH, RWMA, Mild MR
EF 60%, Normal
EF 38%, LVDD, RWMA
EF 56%, RWMA, Severe TR, PAH, LVDD
EF 60%, Concentric LVH, Severe TR, Severe PAH
EF 62%, Normal
EF 40%, Concentric LVH
EF 35 %, Global Hypokinesia
EF 45%, Concentric LVH
EF 45%, Concentric LVH, RWMA, Mild MR
EF 60%,mild MR, TR, PAH, LVDD
EF 40%, Concentric LVH LV GLOBAL HYPOKINESIA
EF 70%, Concentric LVH, LVDD
EF 60%, Normal
EF 60%,mild MR, TR, PAH, LVDD
EF 55% NORMAL

USG ABDOMEN
Bilateral Small Sized Kidneys
Normal Sized Kidneys, Grade 2 RPC
Bilateral Small Sized Kidnyes with Multiple Cysts
Bilateral Small Sized Kidnyes with Grade 2 RPC
Normal
Bilateral Small Sized Kidneys
Bilateral Small Sized Kidneys
Bilateral Small Sized Kidneys
Bilateral Small Sized Kidneys
NORMAL
Bilateral Small Sized Kidneys
Bilateral Small Sized Kidneys
Bilateral Small Sized Kidneys
Bilateral Small Sized Kidneys
Normal
Bilateral Small Sized Kidneys
Bilateral Small Sized Kidneys
NORMAL
NORMAL
NORMAL
NORMAL
Heptospspleenomegaly
Multiple cysts in liver and kidney
NORMAL
Bilateral Small Sized Kidneys
Bilateral Small Sized Kidneys
NORMAL
Bilateral Small Sized Kidneys
Bilateral Small Sized Kidneys
Bilateral Small Sized Kidneys

ECG
Normal
LVH
LVH
LVH
LVH
LVH
LVH
LVH, OLD IWMI
LVH, OLD IWMI
OLD AWMI, LVH
OLD IWMI
OLD AWMI
LVH
LVH,OLD IWMI
OLD IWMI
LVH
OLD AWMI
1 Degree Heart Block
LVH
LVH
LVH
LVH, OLD AWMI
LVH
LVH OLD IWMI
OLD IWMI
LVH
WPW Syndrome
LVH
OLD IWMI
LVH, OLD IWMI

RDI/Hour AHI
50.3
50.3
163.1
163.6
66.9
66.9
145.5
145.5
45.2
44.5
48.1
48.1
46
46
34.9
29.8
94.6
94.6
172
172
169.1
169.1
169.1
169.1
64.7
64.7
189.1
189.1
72.3
72.3
54.1
54.1
163.4
163.4
82.7
82.7
175.7
175.7
50.1
50.1
80.7
80.6
92.8
91.7
64
64
179.7
179.7
38.7
38.7
54.1
54.1
119.4
119.4
63.8
63.8
66.5
66.5
163.1
163.1

POLYSOMNOGRAPHY
AROUSAL INDEX ODI % TSD Mins PLM/Hour IMPRESSION
33.5
7.1
325.5
16.3 Moderate OSA
66.9 19.3
469
84 Severe OSA
45.4
9.6
305
2.2 Severe OSA
122.5 18.3
142.5
18.1 severe SARD with OSA and CA
42
5.1
376
12.6 Severe OSA
21.8
1.8
394
5 Severe OSA
40
3.6
428
21.26 Severe OSA
36.3
0.5
407
15.6 Severe OSA
83.2 77.3
336
20 Severe OSA
102 50.7
387
15.6 Moderate OSA
87 30.4
407
27 Severe OSA
87 30.4
407
27 OSA
33.9 75.3
241
1.2 Severe OSA
88 35.4
397
29 OSA
47.4
20
310
4 Severe OSA
49.9
28
425
13.8 Severe OSA
89 33.4
407
27 Moderate OSA
80 49.8
417
30.2 Moderate OSA
100.7 49.9
360
16.8 Severe OSA
49.9
29
420
14 Severe OSA
81 49.8
407
32.1 Moderate OSA
92.7 23.9
364.5
10.2 Moderate OSA
33
77
244
1.5 Severe OSA
107.7 49.9
357
14.8 Moderate OSA
34.5 20.4
285.5
20.4 Severe OSA
49.9
28
425
13.8 Severe OSA
54.5 29.5
404.5
27.4 Severe OSA
63.3 56.1
413
9.2 Severe OSA
19.5 17.4
304
81.9 Severe OSA
66.9 19.3
405.5
84 OSA

Compatibility Report for master chart thesis osa.xls

Run on 2/15/2007 20:01
The following features in this workbook are not supported by earlier versions of
Excel. These features may be lost or degraded when you save this workbook in
an earlier file format.
Minor loss of fidelity
Some cells or styles in this workbook contain formatting that is not supported
by the selected file format. These formats will be converted to the closest
format available.

# of occurrences
7

Compatibility Report for master chart thesis osa.xls

Run on 2/16/2007 2:14
The following features in this workbook are not supported by earlier versions of
Excel. These features may be lost or degraded when you save this workbook in
an earlier file format.
Minor loss of fidelity
Some cells or styles in this workbook contain formatting that is not supported
by the selected file format. These formats will be converted to the closest
format available.

# of occurrences
9

Compatibility Report for master chart thesis osa.xls

Run on 3/4/2007 5:41
The following features in this workbook are not supported by earlier versions of
Excel. These features may be lost or degraded when you save this workbook in
an earlier file format.
Minor loss of fidelity
Some cells or styles in this workbook contain formatting that is not supported
by the selected file format. These formats will be converted to the closest
format available.

# of occurrences
32