1. apoptosis is stimulated by TNF 2. genetic disorder is not a cuase of 2nd immuno deficiency 3.

IgG is the most common antibody in the CVID 4. IL-12 is produced by macrophage 5. imiquimod is not an immuno suppressive drug 6. MHC : T-cell that recognize peptide which are bond to self MHC molecules 7. tetanus toxide : is an artificial active immunity vaccine 8. carcinoembryonec antigine is an tumor antigine that is a developmental protine 9. plasma cells are affected by the bence jones protine (type of cancer) 10. cyclosporine blocks the calcinurine 11. serum sickness is caused by anti-horse serum antibodies 12. aspirine inhabit prostaglandin 13. abo compatability is the first step to be cheked in the transplantation process 14. gp120 bends to Cd4 and chemokine receptor in HIV 15. double negative stage : stage in T-cell development where cometment to gamma delta lineage occurs 16. cord blood is the best source of the stem cells 17. human herpes virus B dosent match with lymphoma 18. M.avium comes with the severest stage of T-cell depletion 19. production of human mouse antibodies due to disadvantage of monocolonal mouse antibody 20. HER-2 gives breast cancer 21. Cd40 ligand mutation cause hyper IgM syndrome with low IgG and IgA 22. HIV attacks gilial cells 23. chimeric and humanized antibodies reduce the risk of human antimouse antibodies production 24. multiple sclerosis clue is oligocolonal bands in CSF electrophoresis that are not present in serum electrophoresis 25. ALL (acute lymphoplastic leuckemia ) is happened due to pre b cells 26. c5-c9 cause complement deficiency that cause repeat infection by neisseria 27. phosphor lipase C is not involved in the respiratory burst 28. TH2 cells ---- IL-6 miss match / mast cell ------ IL-10 underlined much correct 29. NK cell is activated by down regulation of MHC 30. wisko aldresh syndrome symptoms are : eczema low palatelet infection and malignancy 31. HLA cross matching used to detect antibodies against donor HLA 32. EBV is associated with burkitts lymphoma 33. bone marrow transplantation is the most difficult procedure and need best hla matching 34. Cd3 will be the least in the FACS machine in the patient who has rare pan T-cell defecincy 35. PEG molecules increase the half-life of an cytokine 36. oncogene is the gene that is related to cancer 37. T-cell signaling blockade drugs are cyclosporine and tacrolimus 38. TCR dont goes under somatic hyper mutation to get better fit receptor

39. a drug that interfere with a tap molecule help blocking the AG expresseion on MHC I 40. paracortex is the most affected part of the lymph node in the digorgea syndrome 41. IL-12 production, Cd28 and B7 , Cd 40 and Cd40 L , and cross linking of B-cell receptor with polymeric antigen HELPS IN THE PRODUCTION OF MEMORY CELLS 42. JAK42 +SATA1 +STAT 3 all involved in il2 signaling 43. wegners granulomatosis is a patient with cANCA 44. IgM and anti-IgG are antibodies that involved in the pathogenasis of a disease that has symptoms like ESR high CRP high rheumatic factor and pain in hand and wrist 45. febrile non hemolytic anemia give rise to donor ABS agains recipient nuetrophils 46. allogenic is the transplantation between the same species 47. HTLV-1 cause adult T-cell lymphoma 48. AG and cytokine helps to activate B-cell 49. baciliximab works as anti IL-2 receptor 50. HLA-DQ2 is associated with celiac disease 51. TDT is not for t-cell signaling 52. in celiac disease the serum contain anti endomysial IgA 53. when gamma chain gene is selected following isotype switching and the development of memory cell then IgG can be expressed on the surface of B-cell 54. contact dermatitis takes a long time to develop after exposure to antigen 55. TLR used to recognition in the gram negative bacteria 56. abnormal NBT test comes with lung and skin infection and stapeluaureus with normal PMN 57. the acidity of the lysosomes are affected by the hypochlorus acid 58. HLA association can lead to autoimmune disease 59. thymus is the most protine u can find on developing t-cell 60. indirect coombs test used to do a cross match between donors rbcs and recipient serum 61. ms has Cd4+ involvement so we will have IFN-gamma , IL2 62. allelic exclusion is when RAG-1 and RAG-2 start to be down regulated so B-cell can have it spacifity of each cell 63. wiskot Aldrich syndrome affect actin 64. MHC 1 and 2 are constitutivly expressed by B-cells 65. C4 can be activated by the MBL 66. BCG vaccine are used in the active treatment of cancer 67. C1Q needs AB binding ABU ADAM ZEZO