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IV B.Tech I Semester Regular Examinations, November 2007
BIO PHARMACEUTICAL TECHNOLOGY
(Bio-Technology)
Time: 3 hours Max Marks: 80
Answer any FIVE Questions
All Questions carry equal marks
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2. Which physiochemical properties of the drug limit its distribution, describe in de-
tail? [16]
3. (a) Explain why doubling the dose of a drug does not double the pharmacody-
namic effects of the drug. [8]
(b) Answer any Two of the following.
i. Pharmacodynomics
ii. Therapeutic range
iii. Quantal response
iv. Graded response. [4+4]
4. (a) What is the filtration process? How you are going to select filter in the case
of filter selection procedure in the bulk drug manufacturing?
(b) What are cartridge filters? Explain clearly. [8+8]
6. Write about different excepients used in the manufacture of parenteral dosage forms.
[16]
8. Write about non-steroidal contraceptives like Estrogens and their side effects. [16]
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Code No: RR412303 Set No. 2
IV B.Tech I Semester Regular Examinations, November 2007
BIO PHARMACEUTICAL TECHNOLOGY
(Bio-Technology)
Time: 3 hours Max Marks: 80
Answer any FIVE Questions
All Questions carry equal marks
⋆⋆⋆⋆⋆
1. (a) Define the term “Antidepressant”. Briefly describe the chemical classification
of antidepressants. [8]
(b) Write structures and uses of the following drugs.
i. Penicilline
ii. Phenelzine sulfate (Nordil)
iii. Antriptyline hydro chloride(Enovil) [2+3+3]
2. Why is distribution of a drug not uniform throughout the body? List the factors
influencing drug distribution. [16]
4. What are the different types of reactions involved in the case of bulk drug manu-
facturing. [16]
6. Write about different preservatives & anti oxidants used in the manufacture of the
parenteral dosage forms. [16]
8. Write about non-steroidal contraceptives like Estrogens and their side effects. [16]
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Code No: RR412303 Set No. 3
IV B.Tech I Semester Regular Examinations, November 2007
BIO PHARMACEUTICAL TECHNOLOGY
(Bio-Technology)
Time: 3 hours Max Marks: 80
Answer any FIVE Questions
All Questions carry equal marks
⋆⋆⋆⋆⋆
2. Which physiochemical properties of the drug limit its distribution, describe in de-
tail? [16]
3. (a) Define Pharmacokinetics. Name and define the three pharmacokinetic para-
meters that describe a typical plasma level - time curve.
(b) What are the various pharamcodynamic parameters? [8+8]
4. What are the different types of purification techniques used in the case of bulk drug
manufacturing process? [16]
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Code No: RR412303 Set No. 4
IV B.Tech I Semester Regular Examinations, November 2007
BIO PHARMACEUTICAL TECHNOLOGY
(Bio-Technology)
Time: 3 hours Max Marks: 80
Answer any FIVE Questions
All Questions carry equal marks
⋆⋆⋆⋆⋆
1. (a) What are adrenergic agents? Give details of these agents. [8]
(b) Give the chemical structure and uses of the following.
i. Asprin
ii. Salbutamol sulphate
iii. paracetamol. [2+3+3M ]
2. What are the characteristics of specialized transport systems? How can the Kinetics
of such processes may be described? [16]
3. Why Pharmacokinetic models are more important in the case of drug metabolism,
explain in detail? [16]
4. What is the importance of the flow sheet in the bulk drug manufacturing? Describe
about different types of general reactions involved in the bulk drug production. [16]
6. Write about different excepients used in the manufacture of parenteral dosage forms.
[16]
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