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Hypertension Research (2010) 33, 668–669; doi:10.1038/hr.2010.96; published online 10 June 2010
pulse wave velocity or cervical echo analysis. 3 Merchenthaler I, Dellovade TL, Shughrue PJ. Neuro- 7 Kobayashi S, Okada K, Koide H, Bokura H, Yamaguchi
protection by estrogen in animal models of global S. Subcortical silent brain infarction as a risk factor for
Diurnal blood pressure variations measured and focal ischemia. Ann NY Acad Sci 2003; 1007: clinical stroke. Stroke 1997; 28: 1932–1939.
with ambulatory blood pressure monitoring 89–100. 8 Bokura H, Kobayashi S, Yamaguchi S, Iijima K, Nagai
4 Anderson GL, Limacher M, Assaf AR, Bassford T, A, Toyoda G, Oguro H, Takahashi K. Silent brain
for assessing the role of heart diseases, Beresford SA, Black H, Bonds D, Brunner R, infarction and subcortical white matter lesions increase
endothelial dysfunction, and extreme dipper Brzyski R, Caan B, Chlebowski R, Curb D, Gass M, the risk of stroke and mortality: a prospective cohort
and non-dipper types could also be useful for Hays J, Heiss G, Hendrix S, Howard BV, Hsia J, study. J Stroke Cerebrovasc Dis 2006; 15: 57–63.
Hubbell A, Jackson R, Johnson KC, Judd H, Kotchen 9 Kwon HM, Kim BJ, Lee SH, Choi SH, Oh BH, Yoon BW.
studying the gender differences of SBI. JM, Kuller L, LaCroix AZ, Lane D, Langer RD, Metabolic syndrome as an independent risk factor of
Furthermore, the relation between vascular Lasser N, Lewis CE, Manson J, Margolis K, Ockene J, silent brain infarction in healthy people. Stroke 2006;
cognitive impairment and SBI in the elderly O’Sullivan MJ, Phillips L, Prentice RL, Ritenbaugh C, 37: 466–470.
Robbins J, Rossouw JE, Sarto G, Stefanick ML, 10 Vermeer SE, Koudstaal PJ, Oudkerk M, Hofman A,
population is a current topic of study. Further Van Horn L, Wactawski-Wende J, Wallace R, Breteler MM. Prevalence and risk factors of silent
investigations will help us understand more Wassertheil-Smoller S, Women’s Health Initiative brain infarcts in the population-based Rotterdam
Steering Committee. Effects of conjugated Scan Study. Stroke 2002; 33: 21–25.
about the gender differences of SBI. We can equine estrogen in postmenopausal women with hyster- 11 Kario K, Shimada K, Schwartz JE, Matsuo T,
learn more about gender-specific medicine ectomy: the Women’s Health Initiative Hoshide S, Pickering TG. Silent and clinically overt
for stroke by listening to the sound of silence randomized controlled trial. JAMA 2004; 291: stroke in older Japanese subjects with white-coat and
1701–1712. sustained hypertension. J Am Coll Cardiol 2001; 38:
between men and women. 5 Price TR, Manolio TA, Kronmal RA, Kittner SJ, Yue NC, 238–245.
Robbins J, Anton-Culver H, O’Leary DH. Silent brain 12 Takashima Y, Miwa Y, Mori T, Hashimoto M, Uchino A,
infarction on magnetic resonance imaging and neuro- Yuzuriha T, Sasaguri T, Yao H. Sex differences in the
logical abnormalities in community-dwelling older risk profile and male predominance in silent brain
adults. The Cardiovascular Health Study. CHS infarction in community-dwelling elderly subjects: the
1 Appelros P, Stegmayr B, Terent A. Sex differences in Collaborative Research Group. Stroke 1997; 28: Sefuri Brain MRI Study. Hypertens Res 2010; 33:
stroke epidemiology: a systematic review. Stroke 2009; 1158–1164. 748–752.
40: 1082–1090. 6 Howard G, Wagenknecht LE, Cai J, Cooper L, Kraut MA, 13 Kubo M, Hata J, Doi Y, Tanizaki Y, Iida M, Kiyohara Y.
2 Duckles SP, Krause DN. Cerebrovascular effects of Toole JF. Cigarette smoking and other risk factors for Secular trends in the incidence of and risk factors for
oestrogen: multiplicity of action. Clin Exp Pharmacol silent cerebral infarction in the general population. ischemic stroke and its subtypes in Japanese popula-
Physiol 2007; 34: 801–808. Stroke 1998; 29: 913–917. tion. Circulation 2008; 118: 2672–2678.
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