Drug Study: Drug 1.

Cefuroxime Dosage 750mg IV q8 Indication As for the other cephalosporins, although as a secondgeneration it is less susceptible to Beta-lactamase and so may have greater activity against Haemophilus influenzae, Neisseria gonorrhoeae and Lyme disease Contraindications Hypersensitivity to cephalosporins. Side Effects >Allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. >Serious Side effects: diarrhea that is watery or bloody; fever, sore throat, and head ache with a severe blistering, peeling, and red skin rash; seizure (black-out or convulsions);or jaundice(yellowing of the eyes or skin). >Less Serious Side Effects: nausea, vomiting, diarrhea, stomach pain; headache, dizziness; fussiness of crying (in children);sleep problems(insomnia); or vaginal itching or discharge.

2. Tramadol

50mg IV q6

Moderate to severe pain

Acute alcohol intoxication. Hypnotics, centrally-acting analgesics, opioids or psychotropic drugs. Treatment with MAOI's or within 2wk from withdrawal. Children <12yr. Patients with active peptic ulcer disease, in patients with recent gastrointestinal bleeding or perforation, and in patients with a history of

Nausea, vomiting, diarrhea, constipation. Tiredness, drowsiness, dizziness, headache, confusion, hallucinations,. Skin rashes, tachycardia, orthostatic hypotension, bradycardia, flushing, allergic reactions

3. Ketorolac

30mg IV q6

Short-term management of moderate to severe post op pain

G.I. ulceration, bleeding and perforation, postoperative bleeding, acute renal failure, anaphylactic and anaphylactoid reactions, and liver failure

peptic ulcer disease or gastrointestinal bleeding. 4. Paracetamol 300mg IV q6 Reduces fever and relieves the muscular pain characteristic of influenza. This is a nontoxic drug that has excellent gastric tolerance and is increasingly accepted and used. Contraindicated in patients Hypersensitive to the drug. Use cautiously in patients with long term alcohol use because therapeutic doses cause hepatotoxicity in these patients. Hematologic: hemolytic anemia, neutropenia, leucopenia, pancytopenia. Hepatic: Jaundice Metabolic: Hypoglycemia Skin: rash, urticaria. Hypersensitivity to omeprazole or to any of its components. When taken at the recommended dose, side-effects of paracetamol are rare. Skin rashes, blood disorders and a swollen pancreas have occasionally happened in people taking the drug on a regular basis for a long time. One advantage of paracetamol over aspirin and similar drugs (eg ibuprofen

5. Omeprazole

40mg IV

-As an alternative for patients who cannot tolerate oral therapy in the following conditions: benign gastric ulcer, duodenal ulcer, gastroesophageal reflux disease. -Acid aspiration prophylaxis

Generally mild and reversible. Dermatologic: skin rash, urticaria, pruritus Gastrointestinal: constipation, diarrhea, flatulence, nausea, vomiting, acid regurgitation, abdominal pain, Others: asthenia, headache, photosensitivity, dizziness, lightheadedness, arthritic and myalgic symptoms, paraesthesia.

Nursing Care Plan: Assessment Objective: -dressing dry and intact Diagnosis Risk for infection related to inadequate defense to surgical incision Planning After 2 hours of nursing intervention, patient will be able to understand causative factors, identify signs of infection and report them to health care provider accordingly. Implementation Independent: -Monitor vital signs -Inspect dressing and perform wound care -Monitor elevated temperature, redness, swelling, increased pain, or purulent drainage at incisions -Wash hands and teach other caregivers to wash hands before contact with patient and between procedures with patient. -Encourage fluid intake of 2000 ml to 3000 ml of water per day(unless contraindicated).Encourage coughing and deep breathing Independent: Administer antibiotics Rationale -To establish a baseline data -Moist from drainage can be a source of infection -these are signs of infection -Friction and running water effectively remove microorganisms from hands. Washing between procedures reduces the risk of transmitting pathogens from one area of the body to another -Fluids promote diluted urine and frequent emptying of bladder -Antibiotics have bactericidal effect that combats pathogens Evaluation Patient is expected to be free of infection, as evidenced by normal vital signs and absence of purulent drainage from wounds, incisions, and tubes.