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As our understanding of the mechanism of anesthesia has improved it has only increased the questions about the depth of anesthesia. Moreover, the evidence available is not compelling enough to make the depth of anesthesia monitoring a requirement or a standard yet. We have a choice of monitors to help assess the depth of anesthesia but the search for a better monitor continues. References: 1.Kissin I. Depth of Anesthesia and Bispectral Index Monitoring. Anesth Analg 2000;90: 1114-7 2.Kalkman JMD, Peelen LM, Moons KG. Pick up the Pieces: Depth of Anesthesia and Long-term Mortality. Anesthesiology 2011; 114: 485-487 3.Musizza B, Ribirac S. Monitoring the Depth of Anaesthesia. Sensors 2010; 10(12): 10896-935