DRUG STUDY Drug Biperiden hydrochlorid e (Akineton) 2mg PRN Classificatio ns Anticholinergic , Antiparkinsoni an drug Mechanism of Action Blocks

central cholinergic receptors, helping to balance cholinergic activity in the basal ganglia. Contraindication Adverse Actual Findings s Reaction adjunct in the Hypersensitivity to Anxiety, Dry mouth therapy of all biperiden euphoria, No signs of EPS forms of confusion, parkinsonism Narrow angle delirium, (idiopathic, glaucoma hallucinations, postencephali drowsiness, tic, Bowel obstruction memory arterioscleroti impairment, c) Megacolon ataxia, mydriasis, Control of tachycardia, extrapyramid bradycardia, al disorders dry mouth, secondary to constipation. neuroleptic Hypersensitivit drug therapy y; reduce rapid eye movement. Indication Nursing Responsibilities Assess for any allergic reactions Administer after meals to avoid gastric irritation Do not use antacids after taking drug.

Assess for any untoward effects Monitor CBC

Classificatio ns Diphenhydram Anticholinergi ine c, hydrochloride Antiparkinsoni (Benadryl) an drug 50 mg HS

Drug

Mechanism of Action Competes with histamine for H1 receptor site. Prevents, but doesnt reverse, histamine mediated responses particularly those of bronchial tubes, GI tract, uterus and blood vessels. Anticholinergi c, Antiparkinson drug

Contraindicatio n Parkinsonism Contraindicated in patients with Used to treat hypersensitivity to anxiety, drug. tension, sleeplessness Avoid use in or patients taking involuntary MAO inhibitors movements due to the Caution in side effects patients with of certain asthma, COPD. psychiatric drugs.

Indication

Adverse Actual Findings Reaction drowsiness, Dry mouth confusion, Sleepiness insomnia, No signs of EPS headache, vertigo, sedation, sleepiness, nervousness, restlessness palpitations, hypotension, tachycardia blurred vision, nasal congestion, tinnitus nausea and vomiting, dry mouth, constipation, urine retention, hemolytic anemia, thrombocytope nia, agranulocytosis thickening of bronchial secretions Urticaria, photosensitivity , rash, anaphylactic shock

Nursing Responsibilities Assess for any allergic reactions Administer after meals to avoid gastric irritation Report difficulty of breathing Administer syrup form if patient is unable to take tablets

Warn patient not to take this drug with any other products that contain diphenhydramine (including topical therapy) because of increased adverse reactions. Assess for any untoward effects

Classificatio Mechanism ns of Action Chlorpromazi Antipsychotic, CNS drugs ne (Thorazine) phenothiazine. Blocks post synaptic dopamine 100 mg OD receptors in the brain.

Drug

Indication Managemen t of psychotic disorders, manic depressive illness.

Contraindication Comatose state, presence of large amounts of CNS depressants, presence of bone marrow depression, hypersensitivity Drowsiness, jaundice, postural hypertension, extra pyramidal reactions. Persistent abdominal movement, cerebral edema, hematologic disord ers, EKG changes

Adverse Actual Findings Reaction neuroleptic Dry mouth malignant Decreased psychotic syndrome, symptoms sedation, extrapyramidal reactions, tardive dyskinesia hypotension (increased with IM, IV) blurred vision, dry eyes, lens opacities constipation, dry mouth, anorexia, hepatitis, ileus urinary retention Hematologic: agranulocytosis , leukopenia photosensitivity , pigment changes, rashes

Nursing Responsibilities Assess for any allergic reactions Assess mental status prior to and periodically during therapy to determine major or minor changes after drug has been taken Monitor vital and I&O signs

Note any seizure disorders. Assess for EPS Assess for constipation and urinary retention.

Drug

Classificatio ns Antipsychotic

Mechanism of Action Alters the effects of dopamine in the CNS Also has anticholinergic and alphaadrenergic blocking activity. Diminished signs and symptoms of psychoses

Indication

Contraindicatio n Comatose conditions, severe CNS depression, Parkinsons disease, lesion of the basal ganglia

Adverse Reaction Extrapyramidal symptoms, tardive dyskinesia, neuroleptic malignant syndrome, other CNS effects, GI symptoms, endocrine effects, CV effects. Hypersensitivity reactions. Occasional reports of mild and usually transient decreases in blood cell counts. Constipation, blurred vision, dry mouth,

Actual Findings Dry mouth Decreased psychotic symptoms

Generic name: haloperidol Brand name: Haldol 5mg HS

Psychotic disorders including schizophrenia. acute psychotic symptoms Relieve hallucinations, delusions, disorganized thinking severe anxiety seizures

Nursing Responsibilitie s Assess mental status prior to and periodically during therapy. Monitor Vital Signs. Take as prescribed. Avoid alcohol Observe patient carefully when administering medication, to ensure that medication is actually taken Report symptoms immediately and monitor for

urinary retention, erectile dysfunction, peripheral edema, excessive perspiration or salivation, heart burn, body temp disregulations

development of neuroleptic malignant syndrome (fever, respiratory distress, tachycardia, seizures, diaphoresis, hypertension or hypotension, pallor, tiredness, severe muscle stiffness, loss of bladder control. May also cause leukocytosis, elevated liver function tests, elevated CPK. )