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HORMONE

TARGET TISSUE

Growth hormone

Most tissue

OVER SECRETION Pituitary gland Anterior Giantism

UNDER SECRETION

Response

Dwarfism

Thyroid-stimulating hormone (TSH) Adrenocorticotropic hormone (ACTH) Melanocyte-stimulating hormone (MSH) Luteinizing hormone (LH) Interstitial cellstimulating hormone (ICSH) Follicle stimulating hormone (FSH)

Thyroid gland

Hyperthyroidism

Hypothyroidism

Adrenal cortex

Darkening of the skin

No adverse symptoms

Melanocyte in skin

Darkening of the skin

No adverse symptoms

Ovaries(female) Testes (male)

Infertility, interfering with menstruation and ovulation

Delayed puberty, hypogonadism reproductive abnormalities

Follicles in ovaries (female) High fertility in women Seminiferous tubules (male)

Prolactin

Ovaries and mammary gland (female) Testes (male) Kidney

Over production of milk

Hypopituitarism, polycystic ovarian syndrome (PCOS), Turner syndrome and Klinefelter syndrome Less production of milk

Antidiuretic hormone (ADH) Oxytoxin

Posterior No adverse symptoms

Diabetes insipidus

Uterus, Mammary gland

Can breastfeed due to high level of lactation

Women are unable to breastfeed

Thyroid hormone: Thyroxine Triiodothyronine Calcitonin

Most cell of the body

Thyroid gland Hypothyroidism

Hyperthyrodism

Primarily bone

No adverse symptoms

Medullary thyroid cancer

Parathyroid hormone

Bone, kidney

Parathyroid gland Hypoparathyroidism

Hyperparathyroidism

Epinephrine (adrenaline) mostly Norepinephrine some

Heart, blood vessel, liver, fat cells

Adrenal medulla insomnia, fatigue, depression, irritability, and digestive difficulties

poor circulation, low blood sugar level ,low blood pressure, low stamina, low self-esteem due to low energy output

Mineralocorticoids (aldosterone) Glucocorticoids (cortisol)

Kidneys (lesser degree) Intestine, sweat glands Most tissue

Adrenal cortex Cushing Syndrome

Addison disease

Cushing Syndrome

Addison disease

Adrenal androgens

Most tissue

No adverse symptoms

adrenal virilism or precocious development of male sex characteristics Hyperglycemia High blood sugar Diabetes Mellitus Hypoglycemia Low blood sugar

Insulin

Liver, skeletal muscle, adipose tissue Liver

Pancreas Hypoglycemia Low blood sugar Hyperglycemia High blood sugar

Glucagon

Testosterone

Most tissues

Reproductive organs Testes hypogonadism

Hypergonadism

Estrogens Progesterone

Most tissues

Ovaries inability to conceive naturally hypogonadism

Endometrial Hyperplasia Hypergonadism

Uterus, ovaries, inflamed tissues Prostaglandins Most tissues

Thymus Thymosin Immune tissues

Melatonin

Hypothalamus

Pineal gland Treats sleeping problems

Insomnia, , high blood pressure, blood clots, heart attack

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