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NEUROTRANSMITTERS
CEREBRUM
• Consists of two hemispheres, the thalamus, the hypothalamus, and the basal
ganglia.
• The cerebral hemispheres are divided into pairs of frontal, parietal, temporal and
occipital lobes
• FRONTAL LOBE
o The largest lobe. This area controls concentration, abstract thought,
information storage or memory, and motor function
o It also contains Broca’s area, a speech association area that participates in
word formulation.
o It is also responsible in large part of individual’s affect, judgement,
personality, and inhibition.
• PARIETAL LOBE
o A predominantly sensory lobe. It contains primary sensory cortex, which
analyzes sensory information and relays the interpretation of this
information to the thalamus and other cortical areas.
o It is also essential to individual’s awareness of the body in space, as well
as orientation in space and spatial relations.
• TEMPORAL
o Contains the auditory receptive areas.
o Contains a vital area called interpretative area that provides integration of
somatization, visual, and auditory areas
o Plays the most dominant role of any of the cortex in cerebration
• OCCIPITAL
o The posterior lobe of the cerebral hemisphere is responsible for visual
interpretation
• CORPUS CALLOSUM
o Is a thick collection of nerve fibers that connects the two hemispheres of
the brain and is responsible for the transmission of information from one
side of the brain to the other.
o Information transferred is sensory, memory, and learned discrimination.
• BASAL GANGLIA
o Are masses of nuclei located deep in the cerebral hemisphere that are
responsible for motor control of fine body movements, including those of
the hands and lower extremities.
• THALAMUS
o Lies on either side of the third ventricle and acts primarily as a relay
station for all sensation except smell.
o All memory, sensation, and pain impulses pass through this section.
• HYPOTHALAMUS
o Is located anterior and inferior to the thalamus.
o It lies immediately beneath and lateral to the lower potion of the wall of
the third ventricle
o It controls the pituitary secretion of hormones that influence metabolism,
reproduction, stress response, and urine production
o Maintain fluid balance and temperature regulation by promoting
vasoconstriction and vasodilation
o Controls and regulates the autonomic nervous system
BRAIN STEM
CEREBELLUM
• Separated from the cerebral hemisphere by a fold of dura mater, the tentorium
cerebelli.
• It has both excitatory and inhibitory actions and is largely responsible for
coordination and movement.
• It also controls fine movement , balance, position sense, and integration of
sensory input.
• The brain is contained in the rigid skull, which protects it from injury
• The major bones of the skull are frontal, temporal, parietal, and occipital bones.
These bones join the at the suture lines.
Meninges
• Fibrous connective tissues that cover the brain and spinal cord.
• It provides protection, support, and nourishment to the brain and spinal cord.
• The layers of the meninges are the dura, arachnoid, and pia mater.
Dura
• The outermost layer
• Covers the brain and the spinal cord
• It is tough, thick, inelastic, fibrous, and gray
Arachnoid
• The middle membrane
• An extremely thin, delicate membrane that closely resembles a spider web
• It appears white because it has no blood supply
• It contains the choroids plexus which is responsible for the production of
CSF
Pia Mater
• The innermost membrane
• A thin, transparent layer that hugs the brain closely and extends into every
folds of the brain’s surface.
Cerebral Circulation
• This is formed by the endothelial cells of the brain’s capillaries, which form
continuous tight junctions, creating a barrier to macromolecules and many
compounds.
• The spinal cord and medulla form a continuous structure extending from the
cerebral hemisphere and serving as the connection between the brain and the
periphery.
• It is approximately 45 cm (18 in) long and about the thickness of a finger.
• It is also consists of gray and white matter. Gray mater is in the center and is
surrounded on all sides by white matter.
• It is surrounded by the meninges, dura, arachnoid, and pia layers.
CRANIAL NERVES
• There re 12 pairs of cranial nerves that emerge from the lower surface of the
brain and pass through the foramina in the skull
• Three are entirely sensory ( I, II, VIII)
• Five are motor (III, IV, VI, XI, and XII)
• Four are mixed (V, VII, IX, and X)
• The cranial nerves are numbered in order in which they arise from the brain
• Most cranial nerves innervate the head, neck, and special sense structures.
SPINAL NERVES
• Regulates the activities of internal organs such as the heart, lungs, blood vessels,
digestive organs, and glands.
• It is also responsible for the maintenance and restoration of internal homeostasis
• It is divided into two: the sympathetic and parasympathetic systems, which
generally acts in opposition to each other.
• It innervates most body organs.
End