HRUK Pulse Winter 2012 WEB

autumn | winter 2012
this issue
Pedalling to Berlin | Great North Run update | Subway 5K gets moving Lauren is the HRUK voice | Facebook like generates 150k |
See page 15 for our new look logo!
PLUS
update on grants 03 project update The first Novel & Emerging

Technology project success 06 Exciting results with new drugs to prevent blood clots 07
LURE Scholars 08 Master Class 09 HRUK special people Fabian pedals his way to Berlin 10 Scaling the heights for loved ones 13 HRUK new look 14 look what weve been up to Hiking for their hearts in all weather 16 Our fantastic Great North Runners 18 Love your Heart Family 5K 20 Heart Research UK in the Midlands BUPA Great Birmingham Run 22 Lauren is the voice of Sing for your Heart in the Midlands 24 company help Its been Simply great to Like us 26 Damart raises money in style 27 Healthy Heart Grants 29 Healthy Heart Feature Healthy gums could protect you against heart disease 31 HRUK Grants 32 HRUK and SUBWAY Healthy Heart Grants 34 Welcome to new team members 36
national directors message

This will be the last edition of Pulse as you see it now because Heart Research UK is getting a facelift. The new look is unveiled on pages 14 & 15. Its not a costly make-over, more a refresh which reflects what weve been doing for the last 45 years but brings us up to date, ready for the next forty-five. Another reason for the change is to highlight the new ways we are spending the money given to us by our generous supporters. As one person put it, pioneering with personality. There are all the usual updates on our medical and Healthy Heart Grants plus stories about the special people that braved the awful weather to achieve their goals or just to challenge themselves. Were also excited about two new company partnerships, with their donations going to projects that will help people live healthier, happier, longer lives. Look out for the feature on dental health and heart disease, it will surprise you how important it is to brush. I hope youll enjoy Pulse.
thanks to our partners
hruk update on grants
update on grants
Nearly 1/2 million for researchers in the latest grant round
Weve given out 466,243 to five Translational Research projects across the UK in our last grant round. First, though, weve highlighted an additional grant given to Birmingham Childrens Hospital to help parents of babies who have had heart surgery.
Mr David Barron Birmingham Childrens Hospital | 36,473 - 2 years Support and surveillance for babies following complex heart surgery
This project will test the feasibility of using a Congenital Heart Assessment Tool (CHAT) and a Home Monitoring Programme (HMP) by parents of young babies who have been discharged home after complex heart surgery. Taking a child home after this sort of surgery can be a daunting prospect at the best of times, but certain types of heart condition also benefit from close surveillance and pre-empting potential problems that might develop. CHAT is a traffic light system, based on the parents observations of their infant such as poor feeding, shortness of breath and urine output, to give an early indication of deterioration of the infants condition. HMP includes daily measurements by parents of the infants oxygen levels and weight. The project will assess whether using HMP together with CHAT improves early recognition of any deterioration in their health compared with CHAT alone or the current discharge advice. The project will educate families and then provide them with direct contact to a trained cardiac liaison nurse. In addition, they will be provided with accurate weighing scales and an oxygen saturation probe to measure the babies daily weight and oxygen levels and then transmit these through a mobile phone device to the hospital. There is good evidence that this level of surveillance saves lives and will empower families and reduce anxiety levels, making them more confident in managing their childs condition.
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update on grants
hruk update on grants
Translational Research Project Grants

Professor Chris Denning University of Nottingham | 146,967 - 24 months Using stem cells to evaluate new treatments for abnormal heart rhythms
In a healthy person, the rhythm of the heart is maintained by coordinated waves of electrical activity produced by chemicals known as ions moving in and out of the heart cells. In patients with Long QT Syndrome (LQTS), the heart can lose its natural rhythm and arrhythmias develop that can lead to fainting, seizures, cardiac arrest and sudden death. Beta-blockers and surgery can help prevent arrhythmias and sudden cardiac death, but these treatments are not always suitable and do not deal with the underlying cause of the condition excessively long heart beats and QT interval. In this project, LQTS patients will donate a small skin sample and genetic tricks will be used in the lab to convert these skin cells into stem cells, which will then be coaxed into heart cells. Using skin cells from healthy people, the stem cell-derived heart cells beat normally but with cells from LQTS patients, the cells develop arrhythmias. The research team has already shown that a number of drugs can prevent arrhythmias and they will now make stem cell-derived heart cells from 20 different LQTS patients to test a much larger range of drugs in the lab.
Professor Luigi Gnudi Kings College London | 75,000 - 36 months Protective role of Nogo-B in cardiorenal vascular disease
Cardiovascular disease and kidney disease have a close relationship, sharing some of the same risk factors such as high blood pressure and diabetes and often existing together as cardiorenal vascular disease in patients with diabetes. Currently, there are no treatments to prevent the progressive decline in kidney function and accompanying increase in cardiovascular risk seen in these patients. There is evidence that a protein called Nogo-B which is produced naturally in the blood vessels - has a protective role and may help to halt the blood vessel damage which happens in cardiorenal vascular disease. Earlier work by this research team has shown that levels of Nogo-B are lower in diabetes and cardiovascular disease.
In this project, the team will investigate whether Nogo-B can protect the blood vessels from the damage which occurs in cardiorenal vascular disease. The researchers will study endothelial progenitor cells a type of cell important for blood vessel repair - from volunteers with type-1 diabetes, with high and low cardiovascular risk. The aim is to understand the role of Nogo-B in these cells and to investigate its potential protective role. A better understanding of the role and protective functions of Nogo-B would represent an important step forward in the development of new treatments for patients at high risk of cardiorenal vascular disease including those with diabetes.
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update on grants
Professor Sarah George Bristol Heart Institute | 130,043 - 24 months Selective gene therapy for vein graft failure
Sections of leg vein are frequently used in heart bypass surgery to get around blocked coronary arteries and improve blood supply to the heart muscle. In around 50% of patients, these vein grafts often become narrowed in the months and years following surgery and, eventually, fail which is not only a problem for the patients needing further treatment, but it also has huge cost implications for the NHS. Earlier work by this team has shown that a specific biochemical pathway activates the cells of the vein graft and encourages thickening of the inner layer of the vein. They will build on this discovery by developing a way of selectively killing only the culprit active cells and help to
avoid side-effects. The researchers have identified a good candidate, a protein which may selectively target only the active cells in the vein graft. Using a combination of techniques, they will assess whether a gene therapy approach can be used to produce this protein in the cells and selectively kill only active cells in the vein graft, thereby preventing vein graft failure. This will be the first study of its kind to assess whether gene therapy can be specifically tailored to the active cells within the vein graft and would benefit patients undergoing graft surgery for blocked arteries in the legs, which is an important problem particularly in the rising numbers of diabetic patients.
Professor Ken Suzuki William Harvey Research Institute, Queen Mary University of London | 111,950 - 12 months Development of a new method for stem cell therapy for heart failure
Transplanting a patients own stem cells is a promising new approach but has serious limitations because most of the stem cells die shortly after grafting and stem cells from diseased, aged patients are likely to have deteriorated function and reduced survival after grafting. Also, the preparation of stem cells requires the patients to endure painful procedures for collection, followed by lengthy lab processes. Recent research has shown that a specific type of stem cell, called mesenchymal stem cells, collected from healthy donors, can be transplanted into patients without causing immune rejection. This research team has also developed a novel bio-engineering technology to produce intact sheets of high-quality stem cells. This project will test the safety and efficacy of the cell-sheet technique in delivering mesenchymal stem cells, from healthy donors, to the heart. It is expected that the stem cells used in this method will survive better and contribute more to the recovery and regeneration of damaged hearts compared to those transplanted by the current methods. If successful, this research will validate a new approach to treating heart failure which may ultimately save lives and improve quality of life of patients.
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update on grants
project update
The first Novel & Emerging Technology project success

Professor John Greenman University of Hull | 199,728 Development of microfluidic devices for analysis of function in normal and diseased cardiac tissue.
HRUK began its unique Novel and Emerging Technologies grant programme in 2007 to encourage blue sky thinking in new technologies such as tissue and bioengineering; developing new devices; nanotechnology; emerging strategies and technologies to manage risk factors; cardiology procedures (eg angioplasty and stent placement), new surgical procedures to cardiovascular disease, improving existing devices and the outcomes of resuscitation after cardiac arrest. All applications must be based on excellent science and clearly describe the future clinical implications and how they can be applied. The first-ever grant for 199,728, was awarded to Prof John Greenman at the University of Hull to develop a new technique for studying heart disease. The project has successfully developed a novel system for keeping human heart tissue alive whilst continuing to beat and function as though it was in the human body. Living tissue needs to be continuously provided with oxygen and nutrients with waste products being removed. The study showed that a number of factors were all critical in keeping the biopsies alive and in a healthy state and the researchers carefully created the best conditions so that tissue samples could be kept alive for up to 24
hours in the lab long enough for appropriate tests to be carried out to study the function of tissue. All tissues release chemicals naturally, but these may change following an intervention such as treatment with a drug. The researchers developed special probes to measure levels of key chemicals released from the tissues to study, in real-time, the changes taking place in the cells, allowing fast analysis within minutes rather than hours as with present testing methods. It is hoped that the system will become an important research tool to help scientists to understand more about the processes involved in heart disease and to develop new treatments. The challenges now are to further progress the new technology and find ways of packaging it for manufacture as a medical device for use in the clinic. Professor Greenmans ultimate vision is that, by directly testing patient samples in a hospital setting, the system could be used for rapid and accurate diagnosis and to help clinicians select the best treatment for individual patients. Earlier this year, Heart Research UK was delighted to present Professor Greenman with the HRUK Outstanding Researcher of the Year Award, in recognition of this successful work.
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project update
project update
Exciting results with new drugs to prevent blood clots

Professor Colin Fishwick University of Leeds | 69,220 New drugs to prevent blood clots
This 69,220 Translational Research Grant awarded to Prof Colin Fishwick at the University of Leeds ran from October 2008 to September 2011 and used special computer programs to design new chemicals to inhibit an enzyme produced by the body, FXIIIA, and tested their effectiveness. Blood clotting is essential to stop bleeding after injury and aid wound healing. However, when blood clots form inside an artery this may lead to a heart attack or stroke. An essential part of the clotting process is the formation of long fibres of the protein fibrin. The body produces an enzyme called factor thirteen (FXIIIA), which welds the fibrin chains together forming a tough mesh and making it very difficult to break down the clot
with anti-thrombosis medicines. Research has shown that by stopping FXIIIA from working, clots are easier to break down with drug treatment or by the bodys own mechanisms. The team also produced some very potent chemicals that inhibited the action of FXIIIA and successfully identified two new classes of FXIIIA inhibitors which represent possible new drug leads. Although there is still more work to do to develop these into safe and effective medicines, these exciting results point the way to the development of a completely new way to treat thrombosis.
HRUK has awarded over 10,600,000 to research projects over the last ten years
For more information on research grants please visit www.heartresearch.org.uk/research
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project update
lure scholars
LURE Scholarships for Dahlia and Euan

Were delighted that two more students from the University of Leeds have been awarded 15,000 each to work on projects to find new ways to treat heart disease. Each year, since 2006, we have sponsored two Leeds Undergraduate Research Enterprise (LURE) scholarships that allow second-year students to take a year out from their medical degree studies and take their first steps on to the research ladder. Dahlia and Euan are set on course to be experts of tomorrow. Euan Bright and Dahlia Abdul-Rahman began their research last summer. Together, their research projects are trying to find important treatments and markers for atherosclerosis, a build-up of fatty deposits (plaque) in the arteries which lead to clots, heart attacks and strokes. The students are both part of wider teams at the University. Euan, 21, from Cambridge, is working on a novel project that is examining patients with acute chest pain caused by plaque build-up in their coronary arteries to see what role a particular enzyme in the blood plays. Euan is hoping that his research project will lead to the enzyme being used as a marker to detect how much plaque is in the coronary arteries which could help identify those at higher risk of a heart attack. He said: This grant has helped me enormously as it has allowed me to do research this summer. The thing that really excites me is linking all this with lifestyle issues such as weight, particularly if you can tie it in with this enzyme marker and lead to treatments that prevent a heart attack. Dahlia, 19, from London, is doing research that involves removing the cells from animal arteries and seeding them with cells from the patient to regenerate them. The hope is that this piece of research will lead to a more effective and safer treatment for vascular disease. Dahlia was very enthusiastic about her scholarship: This has given me a valuable experience and the chance to move something forward that could have an application in the future. Heart Research UKs national director, Barbara Harpham is very enthusiastic about the LURE scheme: The LURE programme is unique and gives, not just practical research experience to the most talented and brightest of their year, but also the chance to learn in internationally-known centres of excellence such as Harvard and Oxford. This is a great opportunity and we wish them well in their future careers. University of Leeds Professor Shervanthi Homer-Vanniasinkam, Consultant Vascular Surgeon, who developed the LURE programme, said: The LURE scholars form a supportive family of enthusiastic and dedicated young people who are committed to improving cardiac and vascular health in this country and beyond.
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project update
master class
First-ever Master Class in Coronary Artery Bypass Grafts

Since we were founded by heart surgeon, David Watson, 45 years ago, Heart Research UK has helped to make surgery safer; funded pioneering medical research; helped develop new techniques and treatments and shared what has been learned. Above all, our aim has been to benefit patients as soon as possible. There have been firsts along the way paying for six of the first eight successful UK heart transplants, establishing the link between smoking and heart disease and buying new devices for patients with failing hearts to be implanted by pioneering surgeons, to name a few. Here is our latest first - a Master Class in by-pass surgery. Sixty per cent of heart operations are coronary artery by-passes but, until recently, there was no practical, hands-on training course on the range of heart bypass techniques, especially using an artery graft, not a vein. HRUK wanted to make sure that these techniques would be available to patients around the country and paid for 36 trainee surgeons from across the UK to attend a Master Class with world-renowned experts. The very successful course, paid for completely by HRUK, and led by Professor David Taggart, Professor of Cardiovascular Surgery at the University of Oxford and Consultant Cardiothoracic Surgeon at John Radcliffe Hospital was held in Oxford. In a series of lectures and video presentations of operations, leading cardiothoracic surgeons from the UK, Italy, Belgium, France and the Netherlands explained the most up to date techniques. The young surgeons also got the chance to practice them in a hands-on, interactive simulation and to find out about new and innovative ways to harvest arteries and veins, explore which are best to use in different situations and how best to graft them on to the heart. Professor David Taggart, who is also a recent past-President of the Society of Cardiothoracic Surgery in Great Britain and Ireland, was delighted with the event. The aim of the class was to encourage the use of more arterial, not vein, grafts in patients undergoing coronary artery bypass grafting. Despite strong evidence of the superiority of multiple arterial grafts, this approach is used in only 10% of all patients. By teaching surgeons the techniques for using multiple arterial grafts, hopefully, this will result in substantial benefits for patients. There is no other similar course in the UK or, indeed, Europe. The enthusiastic response of the delegates who came to this course just shows the need for this teaching. Heart Research UK deserves enormous credit for funding this unique course. Barbara Harpham, our National Director, is sure the Master Class will help clinicians and those needing surgery: The most up-to-date and effective techniques should be available to patients across the UK, especially at their local hospitals. Giving this Master Class, completely free to young surgeons, was a great way to help that happen. It was a great opportunity for them to gain new skills, knowledge and get hands-on experience in a safe and supportive environment. Our charity was founded to make heart surgery safer and fund medical research that would benefit patients as soon as possible. These courses are ideal to do just that.
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HRUK special people

Fabian pedals his way to Berlin
500 miles is a long way by air or train, but on a bike its a major achievement, yet thats exactly what Leeds MP and HRUK Trustee, Fabian Hamilton, did - all the way from Leeds to Berlin. The mammoth ride took him a week and he was met at Berlins Brandenburg Gate, on time and in good health, by the British Ambassador Simon McDonald, Barbara, our National Director and Chairman of Trustees, Richard Hemsley. It was not the end of the road for Fabian. He, and his wife, Rosy, along with his back-up team, were invited to join the British contingent at an event to mark the opening of the London Olympics at the old Tempelhof airport where, on stage in front of hundreds of Berliners, he told them about his trip and shared the spectacle of London 2012. The Leeds MP had many highlights on his trip; the send-off from the Ziff Centre in Leeds, cycling through some picturesque Dutch and German countryside, the small villages and farms, having lunch in a beer garden along the Elbe and some wonderfully long straight stretches of road in Germany without too many hills. On the down side, Fabian noticed some of the towns in the old East Germany still had rough cobbled streets which left him saddle-sore, some sad and rundown districts with shabby old brown brick mills and bahnhofs and problems with his sat nav which, at one point, directed him into a stable full of horses, then onto the motorway forbidden to cyclists. He also had to endure steep rises in temperatures as he cycled across Western Europe and, at one stage, had to contend with 35 degrees a time to ensure he was properly hydrated with lots of water. Fabians reason in raising funds for Heart Research UK stemmed from the death of his father, Mario, from heart failure at the age of just 65 and, as a HRUK Trustee and busy MP, he wanted to do something that would have a big impact as well as raising over 2,200 for the charity. Looking back on his trip, Fabian said, It was a great feeling to have completed my challenge. It was really good to know that everyone had been cheering me on - the tweets, emails and texts that I had and, of course, the generous donations have helped to make the whole endeavour feel worthwhile - thanks to all. Special thanks to my wife, Rosy, for moral support and practical help with a crazy project.
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hruk special people
Youngsters tackle Coast to Coast

Jaydee Duffy, 6, and his brother Bailey, 8, from Leeds are no strangers to walking and hiking - they have already climbed the Yorkshire Three Peaks - but taking on the tough 190-mile Coast to Coast Walk was an amazing feat for the two youngsters. Dad, Lee Galvin, was there all the way, from St Bees Head on the Cumbrian coast to Robin Hoods Bay on the Yorkshire coast, a route crossing the Lake District and the Pennines into Swaledale and ending with a traverse of the Cleveland Hills and the North York Moors. The 15-day trek was done in memory of Lees brother, Christopher, who died at the age of just 15 from cardiomyopathy which led to a deterioration of his heart muscle. The boys and their father really put their walking hobby to good use and were delighted to raise almost 250 for Heart Research UK - a great achievement for such young lads.
Thank you
to everyone who has sent in donations or fundraised for Heart Research UK including:
Hazel Forrest, Kirkby-in-Ashfield | 40 - Coffee morning Jane and Terence Peale, Huddersfield | 200 and Elaine Pamprell, Leigh | 260. Both Ruby Wedding donations Maria Sawbridge, Leicester | 50 - Tombola and raffle Stall Anna Para, London | 2,450; Umesh Patel, Leicester, | 1,880; Ann Hepher, Bedford | 1,416; Heather Laing, Wrexham |225 - Climbing Kilimanjaro Springwater School, Harrogate | 200 - Assistant Heads retirement collection Derek Harding, Kent | 441.25 - Edinburgh Marathon Jasmine Mameen, Essex | 600 - Donation after Ramadan Hornsea Freemasons | 517 donation Majami Tutani, Orpington | 275 - London Triathlon Val Newton, Stockton-on-Tees | 200 - Coast and Castle Cycle Ride Pam and Andrew Bullivant, Ely | 150 - Plant sale Kirk Newsholme Chartered Accountants | 90 - Collection instead of Christmas cards Event Management Students from Leeds Metropolitan University |
80 - 5-a-side football match
Navnit Mistry, Rugby | 425 - Darts match

HRUK special people
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hruk special people
Best-selling Doctor
In 2006, Dr Zeshan Qureshi, then a medical student at the University of Southampton, received a 7,000 research grant from Heart Research UK for an Intercalated BSc degree, working with Professor Nick Curzen. The study, using short TEG, an exciting new test looking at improving medications to prevent blood clots in patients being treated for coronary artery disease, gave Zeshan the opportunity to kick-start his career and led to national prizes, 11 publications and experience presenting research in America, France, Scotland, Bulgaria, England and Canada. Since then, he, along with colleagues, has written and published a medical book which teaches junior doctors how to deal with common medical scenarios. The book, The Unofficial Guide to passing OSCEs, has had a tremendous response and was the bestselling medical book on Amazon for over four and half months, selling over 3,500 copies in over 20 countries and is still extremely popular in helping medical students with their exams. Zeshan is now an Academic Clinical Fellow in Paediatrics at Great Ormond Street and the Institute of Child Health and has donated the 1,000 proceeds from the book towards research into HRUK projects into better treatments for Long QT syndrome, a genetic condition which can cause abnormal heart rhythms, which can lead to fainting, seizures, cardiac arrest and sudden death. What is heartwarming and special for us is that a successful Doctor remembered how his first steps on the research ladder were helped by a grant from Heart Research UK and repaid the faith put in him with such a kind, generous gesture.
Thank you
Catterick school gets a head start
Pupils at Le Cateau Community Primary school in Catterick have sung their hearts out and raised almost 200. They also made over 1,000 during their Enterprise Challenge, when Year five and six classes each were given 100 and asked to make 300 by the end of the school year. Their events included raffles, tea parties and a Mexican Fiesta, with the children coming up with all the ideas, adding up to over 1,300 for Heart Research UK. Head teacher, Grahame Shepherd, said: Its so great to see all the children getting involved in fundraising for such a good cause. They have had so much fun doing the activities and we are very proud of the work they have done for Heart Research UK. All our supporters are special people and some have very special reasons for being involved. Others because they are just generous, kind-hearted people who realise that heart disease can affect all ages and backgrounds. Thank you, most sincerely, to everyone who helps Heart Research UK, no matter how large or small their contribution, it is very much appreciated.
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hruk special people
Scaling the heights for loved ones

Its the Alps for Nick and friends
What happened to Hertfordshire man, Nick Collins father really made him determined to complete his big adventure, and turn personal tragedy into something positive and focus on his Transalpine run in his Dads honour instead. Richard Collins, 47, died in 2005 of cardiomyopathy and, seven years later, Nick and his friends ran 208 miles through the Alps of Germany, Austria and Italy, in his memory. Along the way, they also raised 600. The last time I saw him was on my 21st Birthday, said Nick. I had the chance to spend a lovely time with him, just the two of us that day. I cherish that last hug, the love in his eyes, the honest words and the laughs. On a personal level, I wanted to prove to myself that I could finish this event and when it got tough, I wanted to prove that I have the ability to tough it out... plus the scenery was immense. HRUK is continuing to research treatments for people with my Dads problems. If my efforts can ultimately help others and their families, it would mean all that I am doing is worth it.
Kilimanjaro for Abbie and Alison

Another father was remembered by Abbie Gregory and Alison Church, both 37, when they trekked up Mount Kilimanjaro in Africa and raised a massive 3,000 for Heart Research UK. Paul Fensome was a healthy and active man, even at 70 years old enjoying squash and golf and spending hours on his allotment. He died in February 2011 from a sudden heart attack on his local golf course, at the age of 72. Pauls daughter, Abbie had wanted to climb Kilimanjaro all her life, but had never thought she would. I wanted to do this in honour of my dad by turning something bad into something positive and Kilimanjaro was really the way to do it. I feel very passionate about the work that Heart Research UK carries out because it is so important to find cures that prolong life and give people a second chance that dad never got. Alison added, When Abbie and I started talking about doing this. I never thought it would happen, but Im really proud we have done it in honour of her dad.
hruk special people
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hruk new look
Changes at Heart Research UK

Weve enjoyed celebrating our 45 year anniversary and remembering what weve achieved, but it has made us think, What about the next 45?
Heart Research UK, which began as a small Yorkshire charity to make surgery safer and for the prevention, treatment and cure of heart disease, is now a national organisation funding pioneering medical research and gives grants to community groups of all ages and backgrounds to help them live healthy heart lifestyles. We go into schools; help Brownies achieve their Healthy Heart badge; work with employers to help their colleagues heart health; give information to the public and help young researchers on their first steps on to the research ladder to be the experts of tomorrow. A proud record but, best of all, we are still a friendly, responsive charity with heart. We can tell you where your money goes - not into one big pot - and can even help you set up a personalised fund especially for a something close to your heart. All this will carry on, but we want to do more to help those living with heart disease and, specifically, fill gaps in what is currently being offered to patients, families and clinicians. Weve come up with two new programmes.
Rehabilitating children
The first, is a scheme for youngsters after heart surgery or with a life-long condition to help keep hearts healthy. One in 145 children is born with a congenital heart problem. Some will receive a new heart, others are in and out of hospital for most of their young lives, getting treatment for conditions such as holes in the heart, narrowed valves and more complex defects; some will have an operation and receive little follow-up. Currently, if an adult suffers a heart attack or is hospitalised because of heart problems, they leave hospital fully informed about the type of regime they should follow as well as being offered a full rehab programme, but with youngsters this rarely happens. When we realised that there was a glaring gap, Heart Research UK decided that every childrens heart centre in the UK should have the know-how, personnel and equipment to make sure that every child, and the people who look after them, would leave hospital with a toolkit and access to the exercise aids they need to live the most heart healthy life possible. The scheme will be backed by thorough research and, more importantly, based on advice and practical experiences from those working with children every day.
hruk new look
Master Classes
Talking to clinicians, we felt that, by offering the chance to experience, first hand, state of the art techniques or hear experts in their field talk about their specialities, they could use the knowledge gained for their own patients benefit. They could already attend training sessions, but we wanted more unique Master Classes from leaders and innovators in their field. The first has been held and you read about it on page 9. We dont want to stop there and well keep on looking for new opportunities to make sure our supporters money has the greatest impact on the prevention, treatment and cure of heart disease.
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Please tick this box if you do not wish to hear from Heart Research UK in the future. The policy of Heart Research UK is not to pass names and addresses of our friends and supporters to other organisations. Heart Research UK Freepost RLYL-AGUE-SS BZ, www.heartresearch.org.uk Suite 12D, Josephs Well, Leeds, LS3 1AB T 0113 234
We worked on our new look with Proportion Marketing in Thirsk, North Yorkshire. Vaughan Lonsdale, Director, gives his view on Helping Hearts. HRUK are operating in an increasingly competitive marketplace for donations and This is the new look Heart Research UK. The same logo but with Helping Hearts added. It reflects the warmth and friendliness of our charity and says exactly what we do, not just medical research but all the new things that help people cope with heart disease, prevent it by encouraging healthy heart lifestyles and promoting the best practice and techniques across the country. Heres to our next 45 years.
Our new look
Registered Charity No. 1044821. Registered Ofce: Suite 12D, Josephs Well, Leeds Company limited by guarantee LS3 1AB No. 3026813. Registered in England
www.heartresearch.org.uk
Helping Hearts is exactly what the charity does and this statement completely aligns with the brands core values. Everyones lives are touched by friends, relatives or colleagues suffering from heart disease and this is the perfect positioning statement. Its attractive, unique, and carries the relevant message for their market.
needed a branding strategy that repositioned the organisation to appeal to a broader base of donors but still linking to the brand as a key UK funder of medical research.
Registered Charity Number 1044821
Landscape typeface logo / PRESS / CMYK
Landscape typeface logo
hruk new look

/ MONO / PRESS
at Christmas
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Registere
look what weve been up to
Hiking for their hearts in all weather

Over 300 enthusiastic hikers turned up to brave the rain and wind in Heart Research UKs 16th 25-mile Yorkshire Three Peaks Challenge - a gruelling challenge hiking three of the highest peaks in the Yorkshire Dales - Pen-y-ghent, Whernside and Ingleborough. Most of the walkers began at 7 am and persevered until 1pm, but then, we were advised that Pen-y-ghent and Ingleborough had become unsafe and we were forced to end the event. As HRUKs Denise Armstrong explained, Our main priority had to be the safety of our walkers and, as this was a challenge that welcomed walkers of all abilities, it was essential we had the right safety procedures. Fifty experienced walkers continued and managed to complete all three peaks. The rest were brought back to the HRUK base where they were greeted with a warm welcome, hot tea and their certificate of achievement. We waited until every walker was home to make sure everyone was safe, even though they had signed disclaimers to carry on. 32-year-old, Radoslaw Zrebiec, who had decided to run instead of walk the three peaks, was the first to cross the finish line in an astounding five hours and 30 minutes. Also braving the elements was HRUKs youngest walker ever, seven-year-old J D Anderson who, with his dad, Patrick, completed the challenge in an impressive 11 hours and 30 minutes. The young lad was walking in memory of his grandmother who passed away with a heart attack last year. Proud JD was very tired when I got to the Heart Research UK finishing post, but delighted to discover that I had walked 25 miles in 11 hours. Im glad I took part in memory of my granny, who I miss very much and I know she would have loved to hear all about my challenge. One of the teams to complete the event despite the conditions was a group of staff from the Barclays Bank business team in Bradford. They raised over 660 and Barclays doubled it giving them an impressive 1,300 for HRUK. Work colleagues, Amir Akhtar, Nick Aldridge, Mohammad Atif, Philip Middlebrough and Karen Murphy were truly intrepid. Despite the difficult walking conditions, a twisted knee and a fractured leg, they soldiered on, crossing the finishing line in 11 hours 45 mins.
16 14 www.heartresearch.org.uk/events/yorkshirethreepeakschallenge
If you would like to take part in next years event, please visit:
Love Your Heart Golf Day

Heart Research UKs first fundraising Love Your Heart Golf Day at Howley Hall Golf Club in Leeds was a great success, raising almost 9,000. As well as sponsoring the event, The Miles Group of Huddersfield entered a team of four, with special guest, Alan Starling, the ex- Huddersfield Town goal-keeper. Managing Director of The Miles Group, Geoff Dickinson supported Heart Research UK after being fitted with an aortic heart valve last October.
Rain, rain, go away

It was sunny and warm, then the heavens opened and it poured down. The contrasting weather really put the 30+ Heart Research UK walkers to the test as they took on the challenge of the Jane Tomlinson Walk For All, an event with over 1,000 competitors. Some completed a five-mile event, while others were more adventurous taking on the 14-miles walk. Those who wanted an even bigger challenge completed the full 26-mile course but as the conditions worsened it became tougher for all competitors. All of our walkers were heroes to us at HRUK, each raising valuable funds for our charity by putting their stamina to the test across the tough terrain of the Yorkshire Dales countryside above Settle. People like Christine Hopkins from Grimsby who was doing the five-mile walk for Heart Research UK because her father had heart problems. It was the first time she had done a Dales walk, although she has done other events before. Friends Danielle Welsh and Jodie Greene, both 24, from Leeds were prompted to do the 14-mile walk in memory of their school friend, Matthew Barker, who died, aged just 22, from congenital heart problems. Matthew had familial hypercholesterolaemia, a genetic condition that brings on heart disease at a young age. He died two years ago after getting a first in law at the University of Manchester. Danielle and Jodie decided to run for Heart Research UK to fund more research into heart disease: We saw that the walk had charity partners at the event and, because of our links with Matthew, we felt Heart Research UK was obviously close to home for us, said Danielle. The walk was tough to begin with because of the sun and the steepness and the last couple of miles were really hard with the rain. For Jodie, a letting agent in Leeds, it was also in memory of her father who she lost to heart disease when he was 48 and she was only 11. He suffered from heart disease for 10 years and had a triple bypass operation. The two young women hope to raise about 600 from the walk.
Golf Days are a great and enjoyable way to fundraise for Heart Research UK. If you would like help or advice to organise your own golf event, please contact Lisa Russell on 0113 234 7474 or on yorkshire@heartresearch.org.uk
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Our fantastic Great North Runners

First back
Running enthusiast, Paul Dalton was our first runner home, completing the race in just one hour and 24 minutes, raising 600 for Heart Research UK in recognition of the life-saving heart surgery performed on his wife, Andrea. He said there was a fantastic atmosphere from the crowds during the event and his finishing time exceeded all of his expectations. Paul, 38, who works for Darlington Council, decided to raise funds for us after his wife, Andrea, born with congenital heart problems, had to undergo two major heart operations. He wanted others with similar heart problems to Andrea to benefit from the pioneering research that our charity funds. Paul has been running seriously for the past two years and already had a number of 10k races under his belt, but the BUPA Great North Run was his biggest challenge yet. The race was very congested at the start, but once you are away it is great, said Paul. The people are shouting your name and I also managed to spot one of my colleagues in the crowd. This has been without doubt the best race for atmosphere.
Fundraising duo
Lloyds of London underwriter, Sean Burke, 25, completed the race in about one hour 50 minutes and also said the atmosphere had been unbelievable and people along the route were great. He and his girlfriend, Monika Tamics, wanted to do the race for a heart charity after family members suffered heart problems and chose Heart Research UK.
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First timers
HRUKs own Fundraiser, Lynne Desborough, and husband, Lee, from Leeds did their first Great North Run in two hours 11 minutes and one hour 49 respectively. Lynne said: It was an amazing experience and there was something to remember on each mile - from the Red Arrows flying overhead, the crowds handing out jelly babies to the spine tingling chants going underneath the bridges. What stood out the most for me, though, was the masses of people who were running for a cause including our own Heart Research UK runners who were fantastic. It was an inspirational day, Ive really got the bug and I hope I can get a place for next years event.
Their friend Melanie Purkiss, also completing her first Great North Run, donned a red wig and ran in just under two hours. I have run a few half marathons and this has definitely been the best, said Melanie who is a press officer at the Department for Transport. Katherine McFadzean, a 27-year-old Police Community Support Officer with South Yorkshire Police, completed the race in two hours and 25 minutes and said she was proud to be part of the team running for Heart Research UK. I turned up late so was the last person to start the run. I was just in front of the race sweeper vehicle which actually made me run quicker but it meant I had a lot of people to run past, said Katherine of Higham near Barnsley.
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love your heart 5k
SUBW
VE YOUR H Y LO A
Belfast gets moving

at the HRUK/SUBWAY Love your Heart Family 5K
International gymnast, Louis Smith, was the star guest watching happy families at Ormeau Park, Belfast, enjoying the first Heart Research UK/SUBWAY Love your Heart Family 5K.
The 300 walkers and runners were also cheered on by Belfasts Cool FMs Kirstie McMurray. Weve had a brilliant time today and it has been fantastic to see so many local families enjoying themselves, getting active and raising money for Heart Research UK, said Kirstie, who ran the SUBWAY Love your Heart Family 5K with her 11-year-old daughter Katie. Louis, was there at the start line as families got ready to walk, push and run along the park route. After launching the walk, he said, Im honoured to have been a part of the SUBWAY Love Your Heart Family 5K and it has been great to visit Belfast and see lots of families leading a more active lifestyle. I hope the 5K inspires the people of Northern Ireland to look after their hearts and I wish them all the best on their journeys towards an active, healthy lifestyle. If the happy smiling faces were anything to go by, the day was a big success. Louis showed what a star he was by signing autographs and posing for photographs with his fans and throughout the day, families enjoyed a free family fun day at Ormeau Park, with bouncy castles, face painting and the Cool FM bus. There was also a Low Fat Sub for entrants that went down really well after their exertions. All the money raised from our first Belfast 5K will go to the Heart Research UK and SUBWAY Healthy Heart grant scheme helping people look after their hearts and lead a healthier lifestyle.
T TM EAR
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love your heart 5k
Northern Ireland has a high incidence of heart disease and many of the families taking part were running for very special reasons.
Paula Bacon and her two sons Kayne, seven, and Fraser, three, from East Belfast completed the event in memory of Paulas father and brother. Paulas father, Leslie, a soldier, died at 32 from congenital heart disease whilst serving in Germany. Her brother, Christopher, was diagnosed with the same condition when he was just 18-months-old and, sadly, he also passed away, aged 12, leaving the family devastated. As Paula said, My boys never got the privilege of meeting their uncle, but we know he will be looking down on us proudly.
Chris Farrell, 23, from Newtownards was inspired to take part after his grandfather suffered from angina and his wifes grandparents Mark Smith from Ballymoney got their running shoes on to remember their father, David, and uncle, Mark, who both died from heart attacks. Grace explained how important doing the run was to her and her family, Heart disease has had a huge effect on my family. Eleven members have heart problems or have passed away due to them. Thats scary and we aim to change our fate.
love your heart 5k
had major heart problems. Grace
and
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hruk in the midlands
Heart Research UK in the Midlands

Heart Research UK has spent over 500,000 in universities and hospitals across the Midlands, over the past 10 years, on research into heart disease. This is why we have an office in Birmingham that raises money locally, to be spent locally. Our man in the Midlands is John Lloyd and, along with Joanne Taylor and Maisie Hunspar, our part-timers who both started as volunteers, they make sure Heart Research UK is a well-known charity in the region. Another former volunteer, Sander Kellermans specialty is applying for donations from Trusts and Foundations. Together, they make a hard-working team but we could always do with extra help. If you can spare a few hours to help in the office or be an extra hand at one of many events, please just ring John on 0121 454 1799. Heres a few highlights of whats been going on.
BUPA Great Birmingham Run

Tom raises funds in memory of Nick
Tom Berns, from Birmingham completed his biggest challenge yet to raise funds for Heart Research UK in memory of his friend, Nick Bill, who died aged just 21. Tom, 28, ran the BUPA Great Birmingham Run in just two hours and 28 minutes and has already raised over 640. He raised money for Heart Research UK because he wanted to prevent others from having to deal with losing a friend or loved one through heart disease. Toms friend, Nick, suffered from dilated cardiomyopathy, which caused the enlargement of his left ventricle, the main pumping chamber of the heart. In June 2007, his disease suddenly and swiftly turned into major heart failure. Although he was on medication, and was closely monitored at the Queen Elizabeth Hospital in Birmingham, he was taken to Harefield Hospital in London for emergency surgery. After a good recovery Nick returned home Nick Bill and because he had been fitted with an LVAD (Left Ventricular Assisted Device), doctors were able to give him higher doses of heart medication
and, after a promising echocardiogram, they decided that his heart had recovered and they would be able to remove the LVAD. Tragically, complications arose during surgery and Nick, aged just 21, passed away. His brave battle against heart failure had lasted just over 10 months. Since then, Nicks friends and family have raised almost 74,000 for the Nick Bill Memorial Fund set up with Heart Research UK. The money raised has been used on various projects at Harefield and the Queen Elizabeth Hospitals, ranging from reducing risk of cardiac failure in the young, to researching new methods of identifying quality organs pre-transplantation. The Nick Bill Memorial Fund raises money all year. Their fourth annual golf day at Alton Golf Club was organised by Nicks father, John Bill. 20 teams took part and raised 2,514.00.
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Andrew remembers his Dad

Andrew Lloyd, 37, completed his run of a lifetime in just two hours and 15 minutes in memory of this father, David, who collapsed and died from a heart attack at a Wolverhampton Wanderers football match. Despite the best efforts of the stewards, ambulance service and a doctor, who was a spectator at the game, they were unable to save him. David, who was 64, had suffered heart problems from childhood, including a faulty valve which gave him an irregular heartbeat. The valve had been replaced 15 years ago, prolonging his life. Andrew, from Tividale, Oldbury and his father had been season ticket holders at Wolves for 30 years and had been going to matches together ever since Andrew could remember. Andrew, who has raised over 450, said: Personally, I did this in remembrance and honour of my Dad on what was the first anniversary of his death. I ran for Heart Research UK because of its research and resulting surgical breakthroughs, and my Dad was able to have a longer and more active life than would have been possible without it. I want other families to have that important time and to help prevent other people losing their parents to heart problems. Hopefully, the money we raise can help Heart Research UK continue to prolong and save lives.
Ethans Gift
Brave husband and wife, Andrew and Julie Marshall turned their grief into something very positive when they founded Ethans Gift following the tragic loss of their three-year-old son from congenital heart disease. As Andrew explains: We wanted to increase awareness of congenital heart defects and to raise funds for projects at Birmingham Childrens Hospital in memory of our son, Ethan. He made such an impact in his three short years that my wife Julie and I felt compelled to set up Ethans Gift as our way of supporting the work of the Cardiac Unit. Working alongside Heart Research UK enables us to bring our message to a wider audience and to see our fundraising go into supporting bigger projects. Andrew and Julie are assured that whatever they raise, it will be spent in Birmingham, along with funds from Heart Research UK itself, for projects like the one for baby monitors highlighted in our update on grants. Were delighted to have their support and, together, well help little hearts in Birmingham, and beyond.
Friends take on the Jurassic Trek

There were no dinosaurs on the way for Jonathan Parker, Andrew Smart, Niki Webster and Lisa Sayburn during their trek along Dorsets Jurassic Coast in memory of Ethan Marshall, the son of Jonathans close friends, who died after suffering from a congenital heart defect - transposition of the great arteries. Seeing the strength and determination of Andy and Julie (Ethans mother and Father), Jonathan decided that this was his opportunity to try to raise some money for Ethans Gift. The 94-mile long Jurassic Trek starts at Lyme Regis in Dorset and they completed it in just four days. The route was beautiful and so was the weather for the most part. There are parts of that coastline that I will go back to again and again, Jonathan said. We carried everything with us and spent long days walking from sunrise past sunset. There were sore legs, aching backs and huge blisters but we carried each other through it. The positive attitude of the other three really was encouraging and kept us going each day.
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Lauren is the voice of Sing for your Heart in the Midlands

Fifteen-year-old Lauren Alexandra is Heart Research UKs very own voice in the Midlands. Heading up our Sing for Your Heart week, shes also been very busy raising money for us at events for all ages. Laurens enthusiasm is infectious: I am extremely grateful to Heart Research UK for giving me the opportunity to work with them. Its great to be able to support a national charity that funds so many projects across the Midlands and is passionate about fighting heart disease. Lauren, a student at Bewdley School & Sixth Form Centre, Worcestershire, has been performing as a vocalist around the Midlands for just over 12 months and has her sights set on a career in music or performing arts. Judging by her success so far, stardom is not far away. She was a finalist in the 2012 Next BRIT Thing Midlands; Worcestershire Pop Icons Best Female in 2011 and got through to the Midlands area final for Open Mic UK 2012. Her musical style is powerful and yet packed with emotion and her songs have a variety and maturity that has wide-ranging appeal. Ian Ramage, ex-Sony A&R for UK & Europe echoed our view of Laurens talent after her performance at the Next BRIT Thing Midlands Finals this year: A really strong voice and a stylish one too. Your effervescent personality completely conveyed. Irresistible; you cant not like it. You had a great time, so we had a great time. It sounds like a clich but its true. Its very; very obvious you should be on stage. The natural performing thing, youve just got it. Lauren has been showing just how much she has got it, at events across the Midlands. Seventy guests enjoyed a British-themed afternoon tea buffet and cocktails at the new Temple Street Social Bar & Restaurant, in Birmingham, with the teenager entertaining them throughout the event. On the day, 1,200 was raised for Ethans Gift. At another successful event, the stylish Blue Piano Restaurant in Edgbaston provided a delicious 3-course South East Asian dinner for 60 guests at their Summer Garden Party with songs from the young singing sensation. The event raised 2175.00.
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Sing for your Heart grows and grows

Theres lots of evidence that singing is good for you and your heart. It exercises the lungs, gets the pulse racing as well as making you feel good and thats why we ask people across the UK to raise the roof for Heart Research UK. Sing for your Heart fundraising concerts take place across the West Midlands and the numbers have been growing each year in Sutton Coldfield, Solihull and Birmingham Conservatoire. Local school choirs sing to packed halls with enjoyment radiating not just from the stage but from all the Mums and Dads, family and friends there to cheer them on. During our hectic week, schools, music groups and choirs from across the region also get singing for their heart in shopping malls, outside the supermarket or in school and community halls. Our voice in the Midlands is a very enthusiastic supporter: Im thrilled to be involved in the Sing for Your Heart campaign, said Lauren. Singing is a fun and accessible way of staying fit and healthy, explained Lauren. As a singer I know cardio fitness is important to my well-being, but also to my vocal ability and the endurance required when performing. John Lloyd, Midlands Regional Executive, Heart Research UK explained: Sing for your Heart is rapidly becoming a major event in the Midlands calendar and were very excited and delighted to have Lauren Alexandra headlining our concerts. Lauren is a rising star bursting with talent and has been without doubt a great ambassador for Heart Research UK. Sing for your Heart is an extra special treat for all the school children, choirs and audiences from across the Midlands. Our annual Sing for your Heart week takes places 8 15 December, but some enthusiastic singers use it as a reason to just bring happiness and to keep their hearts healthy at any time. Look out for an event near you or if youd like to be a part of this joyful week, full details are on the HRUK web site: www.heartresearch.org.uk
Love Your Heart

It was a glamorous night of ladies fashion and beauty at the Midlands Love Your Heart evening with over 50 stalls full of everything a woman wants. A high point of the evening was the fashion show by leading designer MOBO, evening gowns from the house of BOW which left the audience thrilled by all the lovely clothes on the catwalk. Much more was on offer with free treatments and goody bags for all and if the future after all the pampering was your thoughts, tarot readings were in big demand.
Waitrose
Shoppers and staff at Waitrose in Harborne, Birmingham have done it again and picked HRUK to benefit from the stores community giving scheme. This is the 4th time we have been selected by the store to receive their donation, after counting the number of green tokens or votes from shoppers. The 450 raised shows that HRUK had 45% of the total tokens and that the Midlands office is having a big impact locally.
Awarding winning fish and chips

Fish and chips is not the usual for Sunday lunch but it was a lovely change from meat and two veg at awardwinning restaurant, Chamberlains Quality Fish & Chips in Birmingham. Winner of the National Fish & Chip Awards 2012s Best Newcomer in the UK to the Fish & Chip industry and the Choice Chip Awards for the Midlands in National Chip Week, the restaurant was the place to be. Thank you to all our supporters in the Midlands.
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company help
Its been Simply great to Like us

Heart Research UK has a new partner. Were delighted to have joined up with Simplyhealth, one of the countrys leading healthcare providers, to champion a campaign that highlights the link between dental health and heart disease.
To kick-start the campaign Simplyhealth launched a television advert that raised awareness of the link and money for Heart Research UK. Its the first time the company has brought its mutual values to life by supporting a charity through its advertising. Its also the first time that Heart Research UK has been featured in an advertisement on national TV and radio. The advert, on digital and terrestrial channels prompted viewers to go to the Simplyhealth UK Facebook page and Like an app. Visitors were also able to read highlights of research from medical institutes, read free health guides on dental health and heart health and watch videos with experts. For every like, the company promised a 1 donation to Heart Research UK. Judging from the current number of likes, the campaign is already a big success with the public and what started as a 30,000 donation from Simplyhealth is now heading towards a massive 150,000. It will pay for a two-year medical research project to look specifically at the link between poor dental hygiene and heart disease. As youll see in the feature later in Pulse, there are real links between poor dental hygiene leading to gum disease and cardiovascular disease. We are backing Simplyhealths dental health campaign with a special Dental care and your heart leaflet, public event and an awareness campaign to highlight that not brushing your teeth regularly can lead to gum disease and, with it, the higher chance of heart disease. Also, Simplyhealth staff will get one-to-one advice from the Heart Research UK Lifestyle team on how to keep their hearts healthy and the best ways to live a healthier, happier, longer life. Look out for the television advert in the coming months. It just shows how likin it can turn into lovin it.
Heart Research UK Help us donate 150,000 to

S IM P L Y H EA
LTH
company help
An apple a day, keeps the doctor away

Fresh, tasty, healthy apples are an ideal way to promote healthy heart eating and when Kanzi Apples approached Heart Research UK, we were very pleased to team up. The new fresh, red apple with a sweetsour flavour is grown in orchards throughout Europe and specially marked packs are being sold through multiple retailers during the 2012-13 season to raise awareness of our new partnership and to promote healthy lifestyles. Kanzi Apples 10,000 donation will be used for educational work with communities focusing on the importance of healthy lifestyles including advice on diet and exercise. James Simpson, Managing Director of Adrian Scripps Ltd, who manages Kanzi Apples in the UK, said they were delighted to be working with our charity and added that our vital medical research played an important role in educating people about heart health. Cyan. Cutter Guide T PRINT DO NO
Damart raises money in style

Its the fifth time that Yorkshire-based fashion brand, Damart, has raised money for Heart Research UKs with the sale of a limited edition t-shirt, raising over 2,000. Their donation will go towards our Helping Little Hearts project to develop a rehabilitation programme for children who have gone through heart surgery or have lifelong heart conditions. Damarts support doesnt end there. They talk the talk and walk the walk of a healthy heart lifestyle with their HRUK Healthy Heart Mark Gold Award, which means they are a top employer by providing a heart healthy workplace. They have put a lot of effort into their award with a number of activities such as their Healthy Summer Salad Meal Deal in the canteen, a Healthy Food Week and a recipe book for staff with lots of ideas on how to eat well for less. The company has also shown great support for their running and walking employers who have entered the London Marathon and the Great North Run. If youd like to find out more about how to become a Healthy Heart Mark employer visit www.heartresearch.org.uk/hearthealth/hhm
Cutter G uide DO NOT Cyan. PRINT
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company help
Beaverbrooks team choice

Each year, the Beaverbrooks Charitable Trust allocates money for their staff to present, as teams, to a charity of their choice. The Web and Marketing team at the companys Head Office in St Annes on Sea has chosen Heart Research UK with a donation of 240. This was because supporting our work was important to Kyle in the Web and Marketing team. Beaverbrooks the Jewellers is a long-standing and highly-valued HRUK supporter, sponsoring our Treasure Chest Appeal envelopes which are filled with unwanted or broken jewellery by our supporters. The jewellery is then auctioned off to raise money for our work. Its recycling at its best and if you would like to clear out your jewellery box or drawer, give us a ring on 0113 234 7474, or send it to Freepost RLYL-AGUE-SSBZ, Heart Research UK, Suite 12D, Josephs Well, Leeds, LS31AB.
Get smart for hearts

Alfa Romeo has been encouraging fashion conscious members of the public to get smart for hearts by wearing one of six specially designed pocket squares. The limited edition pocket squares were handmade using 100% Italian silk in Alfas spiritual home of Italy and designed by some well-known faces from the worlds of sport, business and fashion. Just 6,000 pocket squares, in six unique collectable Alfa Romeo designs, were specially created by Peter Jones from Dragons Den fame; Chris Tomlinson, the Olympic long jumper; Actor, Tom Ellis and Janine Clark, a Young Designer of the Year; the PPQ fashion label and Alfa Romeo. 5 from the sale of each pocket square has been donated to Heart Research UK. The pocket squares are available exclusively for Alfa showrooms or their website www.AlfaRomeo.co.uk/pocketsquares
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company help
healthy hearts
Healthy Heart Grants

Ten years and still going
It seems like just yesterday that Heart Research UK began its unique Healthy Heart Grant awards, yet, in 2012 we celebrated our 10th anniversary. In those ten years, weve spent over 1.1m helping people to live healthier, happier, longer lives and encouraged over 100 communities of all ages and backgrounds across the country to eat healthier diets, be more active and stop smoking. Weve picked just a few to show how effective they have been. The first two highlight how football, combined with the draw of a popular local professional club can be a powerful vehicle to engage people - especially men - and motivate them to lead healthier lifestyles.
Kicking unhealthy lifestyles into touch

The Motivate team at Notts County FC Football in the Community (FITC) sought out football fans in a bid to reach its target group of sedentary, overweight/obese men with a high waist measurement and, therefore, at an increased risk of heart disease. It visited employers like the Tram and Nottingham City Transport and managed to get nearly seventy men signed up for this 12-week course, some who became quite competitive and often overzealous in the sessions. Dietary advice was given by nutritionists from Nottingham City Care Partnership and the exercise activities laid on by FITC coaches. Fitness and exercise levels increased during the programme, but weight loss was variable, possibly due to participants struggling to give up fried foods and high calorie snacks, but also shift pattern work that affected the regularity of the exercise. A total of 122kg was lost among the 36 participants who completed the week 1 and week 12 measurements, equivalent to the starting weight of many of the men. The equivalent of a whopping 194cm spare tyre was shifted in all and fitness tests improved by 35%. Of the 12 men who responded to the follow-up, 90% had maintained their new weight and fitness levels, one planned to do a half marathon and another had done the Yorkshire Three Peaks. The comments from the men were inspirational and showed they have got a lot out of the sessions:
Being part of a group of people in the same situation helps a great deal. Sharing experiences, problems and solutions helps establish a common goal. You really arent on your own. - Phil I retired just over three years ago and with a change in lifestyle, my weight ballooned by over two stone. All my previous efforts to get back into an exercise regime failed miserably, but then Motivate came along - a structured course over twelve weeks, looking at a more healthy (but not boring or strict) diet and making exercise fun again. - Tim
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healthy heart grants
healthy hearts
Fitter Fans at Everton

Everton in the Communitys programme gave 18 - 35 year old hard to reach men living in deprived areas of Liverpool the chance to improve their heart health and fitness through health workshops and evening football, circuit training and boxing sessions at the Everton Family Centre in Goodison Park. Over 40 men, many of whom were homeless, long-term unemployed and overweight or obese, took part in the weekly sessions. The programme finished on a high when twelve teams battled it out on the pitch in a football tournament that gave everyone a chance to play, whatever their football skills. In addition, a sub-group of 12 men, who were at a higher risk of heart disease and who rarely went to their doctor, took part in a speciallydesigned programme of exercise and fitness and health testing. Many were smokers who did not regularly take part in structured physical exercise or lived in homeless shelters and/or had a history of drug-use. Whilst the power and the reach of the Everton Football Club made it easy to initially engage men, regular participation after was a problem, due to their chaotic lifestyles. This project proved a good learning curve for targeting this particular population. Before I got involved in this project, I hadnt done any exercise for over 10 years and was unable to even walk from the office car park to my desk without getting out of breath. Since starting on the project, I have become much fitter and exercise regularly outside of the course, even cycling to work at least two days per week. It has also helped to reduce my stress levels and blood pressure, improving my ability to do my job. Ian, 32, Liverpool. The Healthy Heart Grants programme is not only about activities; we like to educate and inform as well especially if it can benefit people with particular problems or conditions. This project hit the mark for the visually impaired and, as youll read, for one fortunate bank customer.
Heart Health across the radio waves

Across the UK, two million people have sight loss making it difficult for them to use printed and visual health materials. They can often be isolated, suffer from health conditions (eg diabetes) and lead unhealthy lifestyles. With this in mind, a new series entitled Heart Matters was broadcast from Glasgow by Insight Radio, RNIBs radio station and Europes first and only dedicated radio station for blind and partially sighted people with 155,000 listeners every week. Twenty-four weekly short features were researched and produced, in collaboration with HRUKs Lifestyle team, to raise awareness of heart health and give relevant healthy heart lifestyle information and advice. An interview with HRUK National Director, Barbara Harpham, launched the series and further broadcast topics included diabetes (signs, symptoms, treatment), CPR, smoking cessation,
statins, heart failure, high blood pressure, people of South Asian origin, healthy eating, alcohol, salt intake, fats, exercise, sleep and stress. They featured expert heath advice and personal case studies/testimonies from listeners. People have been emailing in and tweeting following the shows. Off-air, Insight Radio published a dedicated Heart Matters webpage offering weekly updates, podcasts, photographs and links to further information and support. The podcasts remain on the website and will be shared with organisations that have contributed and partners. In December 2011, after the CPR broadcast, a listener who worked in a bank remembered the symptoms of a heart attack and instructions for CPR shed heard on the Heart Matters programme and saved a customers life.
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healthy hearts feature
Healthy gums could protect you against heart disease

This special feature explains why the research on the link between poor dental health and heart disease, paid for by Simplyhealth, through their Facebook campaign, will be so useful. Tooth and gum disease and their effect on the heart have been discussed and researched for many years, but may not always have been flagged up as significant. Recent studies have now highlighted the connection between serious gum disease and the build-up of deposits in the lining of the artery walls leading to blood clots and heart disease. Some researchers have actually found similarities between the type of bacteria found in the mouth and the bacteria found in these fatty deposits in the arteries. One theory suggests that the bacteria involved in gum disease can trigger a low-grade inflammatory response, resulting in changes in the arteries leading to heart attacks and strokes. Another is that bacteria can enter the bloodstream and disturb the way blood vessels dilate. However, proving that poor dental health is a direct risk of heart disease has its difficulties as there are lifestyle factors, such as poor diet, that are implicated in both. Heart disease and inflammation of the gums share similar risk factors, including obesity, diabetes and smoking. By maintaining good oral health you can help to reduce harmful inflammation in the body. Professor Howard Jenkinson, Chair of Oral Microbiology at Bristol University says his team have discovered that if oral Streptococcus bacteria enter the bloodstream through bleeding gums they can wreak havoc by masquerading as human proteins. What our work clearly shows is how important it is to keep your mouth healthy through regular brushing and flossing, to keep these bacteria in check. Further research could lead to new drugs to tackle infective cardiovascular disease. Neglecting oral hygiene and allowing bacteria to build up could increase the chances of these kinds of bacteria getting into the bloodstream. So, following healthy lifestyle choices can help reduce the risk of both diseases. Heres a few things you can do to help protect yourself: Regular visits to the dentist can help early diagnosis of periodontitis (inflammation of the gums) You can keep those gum disease bacteria at bay by brushing your teeth twice a day Use a good toothbrush and fluoride toothpaste and use dental floss daily Giving up cigarettes will keep your mouth feeling fresh and clean, whilst also significantly reducing the risk of developing heart disease Eating plenty of colourful fruit and vegetables will provide a stockpile of antioxidants and help protect against damage to arteries Maintaining a healthy weight for your height is essential for a healthy heart and in the prevention of Type 2 diabetes Participating in at least 30 minutes of exercise every day will help with weight management and reduce the risk of plaque developing on artery walls Remember, good oral hygiene will give you a brighter smile and help keep your heart healthy.
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Latest HRUK Healthy H

Edinburgh: Muslim Womens Association of Edinburgh Beat the Heart!, 1,700
Fifty Muslim girls aged 11 to 18 will be offered a programme of new activities at the leisure centre and local mosque to help them break down the cultural, religious and social barriers they face when accessing physical activity. From women-only fitness classes, mountain biking, a sports leadership course in skipping, to Health 4 U nutrition workshops, there will be plenty of inspiring opportunities and support for them to maintain a healthy heart as they grow up.
Newcastle: Newcastle upon Tyne YMCA YMCA Fitness Challenge Love Your Heart, 3,000
Young people from four deprived areas of Newcastle will be taught about the importance of looking after their hearts through a programme of exercise and healthy eating. Thirty 13 - 25 year olds, including young mums and those from BME communities, will build up their fitness levels through Zumba, Fitness Hula, Skip Trix and Boxercise sessions. They will learn about nutrition in small groups covering topics such as energy balance, food labelling, processed foods and the risk factors for heart disease, and will work with project leaders to improve their lifestyles and overcome some of the barriers to making behaviour changes.
Castleford: Tigers Trust Tiger Heart Beat Project, 9,800

The Castleford Tigers brand will be used to help children gain heart-healthy knowledge, attitudes and behaviour. Primary schools across Castleford will take part in interactive sessions focusing on the heart, exercise and rugby skills, healthy eating, cigarettes and alcohol. Daily logs and questionnaires around their physical activity levels and diet will help coaches to guide pupils into making healthier choices. Club mascots and players will visit schools and teachers will receive information packs and full training so they can continue the workshop activities long term. Prize draw winners from each school will receive a special award at the Tigers Stadium on a match day.
To apply for a
Healthy Heart Grant please go
to www.heartresearch.org.uk/grant/healthyheartgrant Deadlines for applications are 28 February and 31 August each year.
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Heart Grants
Sunderland: SAFC Foundation of Light Heart of The Game, 9,900
Building on the success of their Heart of the Game project (funded through a previous Heart Research UK and SUBWAY Healthy Heart Grant), the Foundation of Light will take their heart-focused programme to every primary school in South Tyneside. Over ten weeks, Year 5 pupils will learn about their hearts, the key ingredients of a heart-healthy diet and will aim to get their hearts beating faster through fun activities such as the circulatory system and salt game. Families will also be invited to take part in two of the sessions. The SAFC Active Bus will roll up at schools across the borough to carry out Health MOTs (heart rate, BMI, body fat etc) and get a snapshot of this age groups health. Up to 1,500 children will be involved and those who improve the most will be invited to a Heart of the Game showcase event during a match at the Stadium of Light.
Liverpool: Liverpool Lighthouse Family H-Art, 9,900

Children and teenagers in Anfield and Everton - two of the most deprived wards in Liverpool where heart disease levels are high - will be learning healthy heart skills through a series of dance, sport and Healthy Heart cooking workshops. Heart rate monitors, pedometers, informal fitness tests, questionnaires and H-Art journals will be used to help young people focus on the health of their hearts. Families will be invited to a celebration healthy meal but also to take part in two events with activities to encourage positive lifestyle choices.
Solihull: Northern Star Community Arts Northern Stars Healthy Hearts, 5,700
An imaginative and fun programme of activities will be offered to people with a learning disability living in North Solihull to help them make heart-healthy lifestyle choices. Forty young people and adults, together with their relatives and carers, will join in with discussions, news sharing and storytelling that cover healthy eating and shopping, mini Olympics (indoor bowls and specialist games) and light exercise classes. Participants will be encouraged to set their own goals around keeping their hearts healthy.
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HRUK and SUBWAY Healthy

Five more SUBWAY Healthy Heart grants
We are delighted to announce another five Heart Research UK and SUBWAYHealthy Heart Grants. Bolton Wanderers Community Trust The HEART of Football, Bolton, 9,000
To encourage 9-13 year olds to look after their hearts and health, heart-focused sessions, supported by player appearances, will feature at 20 primary and three secondary schools across Bolton. Fun, classroom based, handson activities will teach pupils about the heart, heart disease, nutrition and the effects of smoking. Pupils will have this knowledge reinforced as they learn simple daily exercises, try a range of multi-sports and test their fitness to check their progress over the five-week programme. Family workshops will ensure the Healthy Heart message is spread to the wider community and medical partners will be available to discuss any concerns and provide additional advice. Bolton players Keith Andrews and Andy Lonergan joined pupils from SS Simon and Judes Primary School in Bolton on one of the Healthy Heart fun days.
Jets Foundation Hoops 4 Healthy Hearts, Chester, 5,000

Cheshire Jets basketball players will act as positive role models and encourage 9 -11 year olds and their families to get on board with a heart-healthy lifestyle as they tour eight primary schools in Blacon and Ellesmere Port in Cheshire. During the six-week road show, pupils will take part in fun sessions about the heart, a heart-healthy diet, the effects of smoking on the heart, fitness and the importance of exercise and a practical session on basketball. Classes will get additional coaching and the opportunity to enter in a local tournament, with the winners going on to compete in a regional tournament at half-time during a Jets match.
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HRUK and SUBWAY Healthy Heart Grants
y Heart Grants
LaNYT Theatre Dear Heart Youth Theatre Project, Cambridge, 10,000
LaNYTs experience engaging with individuals who are socially and economically marginalised and their ability to create an open, supportive and inspiring environment will help to target young adults in Cambridge, aged 19-30, whose lifestyles put them at a greater risk of heart disease. Dear Heart performing arts workshops will be developed by LaNYT theatre artists, in consultation with cardiac advisors from the University of Cambridge, who will also give talks on heart health. Participants will also be more physically active through dancing, martial arts and movementbased theatre. A Dear Heart Theatre In Education pack that includes key information about the heart, heart disease, heart-healthy eating and real-life stories about cardiac conditions will be produced and handed out to participants.
Bristol Academy Flyers Basketball Club Hoops 4 Healthy Hearts, Bristol, 9,200
Nine to ten year olds from deprived communities in North Bristol will be aiming high with this programme of heart-health education and basketball. Pupils will take part in interactive classroom sessions about the heart and the key steps to keeping it healthy and also have basketball coaching with Professional American Ambassadors, who are role models in many of these communities. Schools will then be invited to play other schools at a festival at the clubs home.
Health and Local Food for Families The Heart Hub, Axminster, 10,000
Residents in Axminster in Devon will be encouraged to put their heart health in focus through activities at the Heart Hub, a food and information centre in the middle of town. A large digital screen will display key heart health messages and visitors will be able to access information, simple seasonal recipes and cooking activities. A community Heart Hub Champion will deliver cookery demonstrations, talks at local fairs and schools and work with Axe Community College to get teenage girls, who are not involved in sport, to take part in a cooking and street dance course.
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HRUK and SUBWAY Healthy Heart Grants
Welcome to new team members

Lisa Russell: Yorkshire Regional Executive
With 13 successful years of fundraising and event management, Lisa, also has extensive experience working with CEOs and senior managers in the corporate and charitable sectors. Lisa feels privileged to work for such a professional organisation. A family member, now 83, has had a triple heart bypass; my friend had an aortic valve fitted and still plays golf twice a week so the cause is close to my heart.
Kathy Thompson: Fundraising Administrator

Kathy has worked for IT companies which led her to travel extensively throughout the UK and Europe. Joining HRUK will be a wonderful opportunity to use my experience and skills to help the charity grow and continue to fund all our innovative programmes.
Lynne Desborough: Fundraiser

Lynne has eight years experience working in the charity sector as a fundraiser and corporate partnership manager with major companies such as Sainsburys, ASDA, Lloyds TSB, Deloitte and Matalan. The world of fundraising is tough right now, but with continued support and a great team to work with I have no doubt the future is bright for our charity.
Chris Child: Communications Manager

Chris was a journalist in Yorkshire for over 20 years, including five as a health correspondent and then spent 15 years at COI, the Governments PR and communications agency. Its such an interesting role with a well-respected charity. My main objective is to raise our profile in all areas so that people know what fantastic work we are doing and encourage them to support Heart Research UK.
Faye Keatley: PR Officer

Faye is this years PR placement student from Leeds Metropolitan University. She is in the third year of a BA Public Relations sandwich course and would eventually like to go into PR. It is a wonderful opportunity for me and I plan to work my hardest to ensure the healthy heart message is spread across the country.
Heart Research UK, Suite 12D, Josephs Well, Leeds LS3 1AB or call 0113 234 7474 Fax: 0113 297 6208 Email: mail@heartresearch.org.uk Website: www.heartresearch.org.uk
Registered Charity No. 1044821 Registered Office: Suite 12D, Josephs Well, Leeds LS3 1AB Company limited by guarantee No. 3026813 Registered in England.

HRUK Pulse Winter 2012 WEB

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autumn | winter 2012

See page 15 for our new look logo!

update on grants 03 project update The first Novel & Emerging

national directors message

thanks to our partners

hruk update on grants

hruk update on grants

Translational Research Project Grants

The first Novel & Emerging Technology project success

Exciting results with new drugs to prevent blood clots

LURE Scholarships for Dahlia and Euan

First-ever Master Class in Coronary Artery Bypass Grafts

HRUK special people

hruk special people

Youngsters tackle Coast to Coast

Navnit Mistry, Rugby | 425 - Darts match

hruk special people

hruk special people

Scaling the heights for loved ones

Kilimanjaro for Abbie and Alison

hruk new look

Changes at Heart Research UK

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Registered Charity Number 1044821

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hruk new look

look what weve been up to

Hiking for their hearts in all weather

Love Your Heart Golf Day

Rain, rain, go away

look what weve been up to

Our fantastic Great North Runners

love your heart 5k

Belfast gets moving

had major heart problems. Grace

hruk in the midlands

Heart Research UK in the Midlands

BUPA Great Birmingham Run

Andrew remembers his Dad

Friends take on the Jurassic Trek

hruk in the midlands

Lauren is the voice of Sing for your Heart in the Midlands

hruk in the midlands

Sing for your Heart grows and grows

Love Your Heart

Awarding winning fish and chips

Its been Simply great to Like us

Heart Research UK Help us donate 150,000 to

An apple a day, keeps the doctor away

Damart raises money in style

Cutter G uide DO NOT Cyan. PRINT

Beaverbrooks team choice

Get smart for hearts

Healthy Heart Grants

Kicking unhealthy lifestyles into touch