Contents

Preface to the fourth edition 6 Preface to the rst edition 7 Part 1 Concepts 1 Structure and classication of bacteria 8 2 Innate immunity and normal ora 10 3 Pathogenicity and pathogenesis of infectious disease 12 4 The laboratory investigation of infection 14 5 Antibacterial therapy 16 6 Antibiotics in clinical use 18 7 Resistance to antibacterial agents 20 8 Sources and transmission of infection 22 9 Principles of infection control 24 10 Infection in the hospital environment 26 11 Immunization 28 12 Emerging infections 30 Part 2 Bacteriology Staphylococcus 32 Streptococcal infections 34 Streptococcus pneumoniae, other Gram-positive cocci and the alpha-haemolytic streptococci 36 Listeria, Bacillus, Corynebacterium and environmental mycobacteria 38 Diphtheria, tetanus and pertussis 40 Pathogenic mycobacteria 42 Clostridium 44 Non-sporing anaerobic infections 46 Neisseria and Moraxella 48 Small Gram-negative coccobacilli: Haemophilus, Brucella, Francisella, Yersinia and Bartonella 50 Pathogenicity of enteric Gram-negative bacteria 52 Enterobacteriaceae clinical syndromes 54 Vibrio, Campylobacter and Helicobacter 56 Environmental pathogens: Pseudomonas, Burkholderia and Legionella 58 Chlamydia, Mycoplasma and Rickettsia 60 Spiral bacteria 62 Part 3 Virology Virus structure, classication and antiviral therapy 64 Herpesviruses I 66 Herpesviruses II 68 DNA viruses: adenovirus, parvovirus and poxvirus 70 Measles, mumps and rubella 72 Inuenza viruses 74 Parainuenza and other respiratory viruses 76 Enterovirus and viruses that infect the gastrointestinal tract 78 37 Hepatitis viruses 80 38 Tropical, exotic or arbovirus infections 82 29 30 31 32 33 34 35 36 Part 4 Mycology 39 Yeast infections 84 40 Filamentous fungi 86

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Companion website
This book is accompanied by a companion website: www.ataglanceseries.com/medicalmicrobiology The website includes: Interactive self-assessment case studies Summaries of key points for each chapter A list of selected online further reading Extra images from the authors digital image bank

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Part 5 Parasitology Intestinal protozoa 88 Malaria, leishmaniasis and trypanosomiasis 90 Gut helminths 92 Tissue helminths 94 Part 6 Systemic infection Congenital and perinatal infections 96 HIV infection and AIDS 98 Pyrexia of unknown origin and septicaemia 100 Endocarditis, myocarditis and pericarditis 102 Infections of the central nervous system 104 Respiratory tract infections 106 Urinary and genital infections 108 Infections of the bones and joints 110 Bacterial diarrhoeal disease 112 Zoonoses 114 Infections in immunocompromised patients 116 Ocular infections 118 Infections of the skin and soft tissue 120 Index 122

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