Chem ch 4 quizbank CH4 chem quiz bank 1.

ID the QC failures in the following levey Jennings polt using your multi rules (fig4-21)

[10x,4R 1-2S] 2. Systematic error can best be described as consisting of:[a constant and proportional error] 3. If two methos agree perfectly in a method comparison study, the slope equals ___ and the y intercept equals ____. [1.0, 0.0] 4. Using the figure (fig 4-22) calculate the systemic error of the test methodat a concentration of 5.0

Chem ch 4 quizbank

[1%] 5. Diagnostic specificity is the [ abitlity of a test to correctly ID the abscene of a given disease or condition] 6. ID the QC failures in the following levey-jennings plot using multirules (fig4-20) more than one choice is appropriate

Chem ch 4 quizbank

[22S,32S] 7. Reference interval transference studies : are used to verify a reference interval 8. Interference studies typically use___ as an interfeirant [all of these: highly icteric/lipemic/hemolyzed samples] 9. Comparison method studies {estimate systemic error] 10. A laboratory test has a true positive=12, false positive = 4, false negative =5, true negative =10. The PPV predictive value of a positive test is [75%] 11. A reference range can be verified by [testing as few as 20 normal donor specimens] 12. For the following series of lab values the vendor hs indicated that a true value is 6.0. Series=5,4,5,6,7,5,3,8,5,9,5,4,5,6. What is my SDI [-0.3] 13. Allowable analytical error is : a combination of random and systemic error 14. An ROC includes all of the following except [perfect test=an area under the curve <1.0] 15. The predictive value of a negative test NPV is [67%] 16. For a Gaussian distributed, what is the likelihood(%) that a data point will be withing 1SD from the mean? [68%] 17. The following chloride (mmol/L) results were obtained using a new analyzer 106 111 104 106 112 110 115 127 83 110 108 109 83 119 105 106 108 114 [108] 18. Using the figure 4-22 what will be the amount of constant error in any measurement?

Chem ch 4 quizbank

19. 20. 21. 22. 23. 24.

[cannot be deteremined] Examples of a typical reference interval data distribution plots include all of the following except [ROC] The correlation coefficient[ indicates the strength of the relationship in a linear regression] A Gaussian distribution is usually [bell-shaped] The following chloride mmol/L results were obtained using a new analyzer 106 111 104 106 112 110 115 127 83 110 108 109 83 119 105 106 108 114 [108.5] To evaluate a moderately complex laboratory test, all of the following must be done except [analytical sensitivity and specificity] For method development studies, which analytical performance test should be done first? [imprecision studies]