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The Evolutionary Systems Biology Team Bacterial Systems Biology Post-doctoral positions

We seek autonomous post-docs with backgrounds in systems biology, synthetic biology, Molecular Biology, Physics or Computer Sciences to enlarge our interdisciplinary group. Open projects target the causes and consequences of natural patterns of phenotypic variability, of aging and death at single-cell level within the context of bacterial lineages. To this end, we unite powerful bacterial genetics, systems and synthetic biology approaches together with state-of-the-art microfluidics, microscopy, robotics, image analysis and modeling to tackle such fundamental questions relevant to all living systems. Our team from diverse backgrounds and nationalities is embedded within the Centre for Research and Interdisciplinarity (The CRI). The CRI harbors international interdisciplinary English-speaking undergrad and graduate programs and is a hub for challenging exchanges amongst faculty and top-notch students. Team members may directly benefit from this environment by participating in the teaching experience at the CRI. Candidates should have relevant scientific background, an excellent track record (including at least one publication as 1st author) and motivation to work in a collaborative interdisciplinary research and teaching environment. Fellowship is available for a 12 month period, with potential extension. In parallel, our postdocs are strongly encouraged and supported to apply for their independent fundings. Apply by sending your CV and detailed motivation to ariel.lindner@inserm.fr
Recent relevant publications
[1] Ni M. et al. (2012) Pre-disposition and epigenetics govern variation in bacterial survival upon stress. PLoS Genet. 2012 Dec;8(12):e1003148. [2] Delebecque CJ et al. (2011) Organization of intracellular reactions with rationally designed RNA assemblies. Science. 333(6041):470-4 [3] Robert L. et al (2010) Pre-dispositions and epigenetic inheritance in the Escherichia coli lactose operon bistable switch. Mol Syst Biol. 6:357. [4] Lindner AB et al. (2009) Protein aggregation as a paradigm of aging, Biochim Biophys Acta 1790 980-96. [5] Lindner AB et al. (2008) Asymmetric segregation of protein aggregates is associated with cellular aging and rejuvenation, Proc Natl Acad Sci U S A 105 (2008) 3076-81.

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The Evolutionary Systems Biology team (head: F. Taddei; senior researcher: A. Lindner), INSERM U1001 Centre for Research and Interdisciplinarity (CRI), Faculty of Medicine, Paris Descartes University. 24 rue du Fbg St Jacques, Paris 14, France. Websites (new release soon!): www.necker.fr/tamara www.cri-paris.org

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