VI.

PATHOPHYSIOLOGY
Predisposing Factors: Age-24 yrs old Trauma Gender-Male Precipitating Factors: Accident-Fall

Force/pressure affects the body

muscle s

bones

Skeletal traction

Tissue injury

Damage to the bones

Fracture at both femur Constipat ion

Cellular and tissue damage Bursting of microvascular circulation Cellular hypoxia Cytokine release Decrease adenosine triphosphate Increase lactic acid production SodiumImpaired potassium cellular breakdown membrane integrity Cellular swelling bruise s

Decrease ability to move

Poor peristalsis

Bisacodyl (Dulcolax) anal suppository

Pregabalin 50 mg TID Ketorolac 30 mg IV q8

Inflammation Pain

Celecoxi b 200mg BID

Increase capillary permeability

Hydroperitone um

Escape of intravascular fluids into peritoneal cavity Increase intra-abdominal pressure Blunt Abdominal Trauma

-Abdominal distention and tenderness - decrease bowel movement

Legend: - Pathology - Signs and Symptoms - Medical Management