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1: Arch Geschwulstforsch. 1988;58(4):235-42.

[Effects of nitrate and ascorbic acid on carcinogenesis in the operated rat stomach] Related Articles

[Article in German] The cancer risk in the stomach subjected to nonresecting

procedures. An experimental long-term[ScandJ GastroenterolSuppl.1984]
study.

Dittrich S, Seffner W, Seidel R. Pathogenesis of carcinoma in operated stomach--an animal

model. [Sb Ved PrLekFakKarlovyUniverzityHradci Kralove.1992]
Chirurgische Klinik des Bezirkskrankenhauses Plauen.
[Carcinoma in the operated stomach of the rat--a tumor model]
[ArchGeschwulstforsch.1984]
In the last few years, a great deal of attention has been paid to the hypothetical relationship
between high nitrate intake, N-nitroso-compounds and gastric cancer. This long term study deals Review A possible role of iron deficiency in gastric cancer in
with the effect of nitrate and ascorbic acid contained in drinking water on the development of Colombia. [Adv Exp Med Biol.1981]
cancer in operated stomachs of rats without additional application of a carcinogen (tumor Review Are nitrates a significant risk factor in human cancer?
model). A total of 147 F1-Hybrids of WELS/Fohm X BD IX--rats were subjected to stomach [Cancer Surv.1989]
operation (Gastroenterostomia antecolica anterior, truncular vagotomy and pyloroplasty).
Carcinomas in stomach occurred within 33 weeks (post operationem). The surgical procedures » See Reviews... | » See All...
altered the gastric flora, resulting in an increase and predominance of nitrate-reducing bacteria.
The maximal tumor rate (10 of 13 rats) occurred in rats with gastroenterostomy and additional Patient Drug Information
nitrate exposition. It may be possible, the nitrate is a precursor of gastric carcinogenesis. But we
could not give any significant evidence of this fact. The addition of ascorbic acid to the drinking Ascorbic Acid (Cecon® Drops, Cenolate® , Cevi-Bid® , ...)
water lead to a suppression of the development of tumors. Our experience with the tumor model Ascorbic acid is used to prevent and treat scurvy, a disease
"operated stomach" underline the multifactorial genesis of stomach cancer in rats. caused by a lack of vitamin C in the body.

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