SUPPLEMENT - May 2010 (Presentations and Publications)

European Association for the Study of the Liver, Vienna, Austria, April 14-18, 2010 Poster Sessions Bruce R. Bacon, Mitchell L. Shiffman, J.K. Kim, A. Berman, Vinod K. Rustgi, Phase 2 Randomized, Double-Blind, Placebo-controlled study of nitazoxanide plus peginterferon and ribavirin in HCV genotype 1 nave patients: Week 12 sustained virologic response rate. Journal of Hepatology 2010;52:S462. R. T. Chung, Adrian M. Di Bisceglie, Fred F. Poordad, T. Hassanein, X Zhou, E. Lentz, A. Prabhakar, F. M. Hamzeh. Association of host phramacodynamic effects and virologic response to peginterferon alfa-2a/ribarivin in patients with chronic hepatitis C. Journal of Hepatology 2010;52::S106. Michael P. Manns, Andrew J. Muir, N. Adda, John G. McHutchison, Norah Terrault, L. Bengtsson, S. George, Adrian M. Di Bisceglie. Improved sustained virologic response (SVR) rates in difficult-to-cure patients treated with Telaprevir in combination with pegintereron alfa2a and ribavirin an analysis from the PROVE3 study. Journal of Hepatology 2010;52:S115. John G. McHutchison, A. J. Thompson, Ira M. Jacobson, Thomas D. Boyer, Eugene R. Schiff, Gregory T. Everson, John M. Vierling, Mitchell L. Shiffman, R. S. Brown, Adrian M. Di Bisceglie, Stuart C. Gordon, William M. Lee, Z. Guo, T. H. King, B. Armstrong, T.C. Rodell, D. Apelian. Pharmacogenomic analysis reveals improved virologic response in all IL28B genotypes in nave gentotype 1 chronic HCV patients treated with GI-5005 therapeutic vaccine plus PEG-IFN/ribavirin. Journal of Hepatology 2010;52:S457. Fred Poordad, John G. McHutchison, Mitchell L. Shiffman, T. Berg, Andrew J. Muir, Michael P. Manns, Adrian M. Di Bisceglie, Norah Terrault, G. Picchio, A. Kwong, L. Bengtsson, S. George, N. Adda. Early virological response profiles with Telaprevir (T) in combination with peginterferon alfa-2a (P) and ribavirin (R) in genotype 1 HCV treatment-nave and treatmentexperienced patients are similar. Journal of Hepatology 2010;52:S121.

Digestive Disease Week 2010, New Orleans May 2-5, 2010 Session Moderators Peter D. Higgins, Bruce R. Bacon. AGA Translational Symposium. Pathogenesis and evaluation of fibrosis in the digestive system. Bruce R. Bacon, Michael B. Fallon. DDW Combined Clinical Symposium. Liver urgencies and emergencies: What you need to know? Adrian M. Di Bisceglie, Russell Wiesner. AGA Clinical Symposium. The hepatocellular carcinoma
epidemic.

Fasiha Kanwal, Robert P. Myers. AASLD Topic Forum. Evidence-based hepatology practice. Brent A. Tetri, Arthur J. McCullough. AASLD Clinical Symposium. Novel approaches to the diagnosis and treatment of NASH. State-of-the Art Lectures Adrian M. Di Bisceglie. Management strategies for hepatocellular carcinoma. Meet-the Professor Luncheons Bruce R. Bacon. Dealing with genetic liver diseases hemochromatosis and Wilson disease. Fasiha Kanwal. Quality improvement in cirrhosis. Brent A. Tetri, Kiran Bambha. Evaluation and treatment of NASH. Charlene Prather. Should we check the stool in IBS? Evidence for old and new assays. Charlene Prather. Addressing the needs of the oldest old: Geriatric gastroenterology at Saint Louis University Medical School. AGA Curbside Consultant Charlene Prather. Difficult motility and functional bowel disorders (CC05). Oral Presentations Cindy X Cai, Rosemary ONeill, Robert S. Britton, Bruce R. Bacon. Differential profibrogenic effects of insulin depending on activation state of hepatic stellate cells. Bruce R. Bacon, Mitchell L. Shiffman, Joseph K. Lim, Arthur Berman, Vinod K. Rustgi, Emmet B. Keeffe. Phase 2 randomized, double-blind, placebo-controlled study of nitazoxanide plus peginterferon and ribavirin in nave patient with chronic hepatitis c genotype 1 infection: final report. Alex S. Befeler, Jill C. Keach, Keith D. Lindor. Serum bile acid profiles after high-dose ursodeoxycholic acid treatment in patients with primary sclerosing cholangitis: Clinical implications. Jules L. Dienstag, Herbert L. Bonkovsky, Hae-Young Kim, Leonard B. Seeff, Adrian M. Di Bisceglie, Gyongyi Szabo, Elizabeth C. Wright. Progression of advanced chronic hepatitis C (CHC): Further follow-up results from the HALT-C trial. Sundip S. Karsan, Fasiha Kanwal, Carl Nordstrom, Edward S. Huang, Inder M. Singh, Marc D. Makhani, Amy Strickland, Brennan M. Spiegel. The impact of elevated INR on outcomes in GI hemorrhage.

Jennifer R. Kramer, Fasiha Kanwal, Minghua Mei, Hashem El-Serag. HCV Treatment and SVR: Gaps in the face of achieving effectiveness in practice. Poster Presentations Syed H. Tariq, Pavan Tummala, John T. Chibnall, Bartlomiej Posnik, Raj Shree, Banke Agarwal. Clinical predictors of pancreatic malignancy in patients > 50 years of age with nonalcoholic/non-gallstone-related acute pancreatitis. Edmundo Rodriguez-Frias, Radikha Kumari, Bruce R. Bacon. Etiology, pathogenesis and treatment patterns of granulomatous liver disease: A seven year single center experience. Fasiha Kanwal, Jennifer R. Kramer, Hashem El-Serag, Youssef Assioun, Bruce R. Bacon, Paula Buchanan, Steven M. Asch. Quality of care in spontaneous bacterial peritonitis. Sombat Treeprasertsuk, Peter L. Jansen, Kris V. Kowdley, Velimir A. Luketic, M. Edwyn Harrison, Timothy M. McCashland, Alex S. Befeler, Denise M. Harnois, Roberta A. Jorgensen, Jill C. Keach, Jeff Schmoll, Tanya Hoskin, Prabin Thapa, Felicity Enders, Keith D. Kindor. The association of low level of both Vitamin A and retinol binding protein with the liver complications in patients with primary sclerosing cholangitis Alina M. Allen, Youssef Assioun, Alex S. Befeler, John M. Richart, Adrian M. Di Bisceglie. Impact of adjuvant chemotherapy on hepatitis C virus reactivation and tumor recurrence in patients with hepatitis C-related hepatocellular carcinoma (HCC) undergoing liver transplantation. Dhiraj Yadav, Adam Slivka, Robert H. Hawes, Randall Brand, Stuart Sherman, Michelle A. Anderson, Peter A. Banks, Michele D Lewis, John Baillie, James A. DiSario, Frank R. Burton, Timothy B Gardner, Stephen T. Amann, Andres Gelrud, Michael R. OConnell, Albert B. Lowenfels, David C. Whitcomb. Smoking is under appreciated as a risk factor for chronic pancreatitis. Received Poster of Distinction Award Digestive. Gregory A. Cote, Dhiraj Yadav, Adam Slivka, Robert H. Hawes, Randall Brand, Michelle A. Anderson, Peter A. Banks, Michele D. Lewis, John Baillie, James A. DiSario, Frank R. Burton, Timothy B. Gardner, Stephen T. Amann, Andres Gelrud, Christopher Lawrence, Michael R. OConnell, David C. Whitcomb, Stuart Sherman. Epidemiology of chronic pancreatitis (CP) at U.S. referral centers: Data from the North American Pancreatitis Study 2 (Naps2). Received Poster of Distinction Award Patric Hawkins, Numan C. Balci, Frank R. Burton, Samer Alkaade, Nabil Choueiri, Sharon Forrest, William H. Perman. Progressive changes of altered perfusion by fast 3D dynamic contrast-enhanced MR imaging pre- and post-secretin seen with increasing changes of chronic pancreatitis on MRCP. Frank R. Burton, Samer Alkaade, Nabil E. Choueiri, Deward D. Purich, Sydney D. Finkelstein. Synthetic human secretin-stimulated exocrine secretion increases endoscopically collected yield of DNA markers for the detection of pancreatic cancer.

Adrian M. Di Bisceglie, Jules L. Dienstag, Mitchell L. Shiffman, Leonard B. Seeff, Herbert L. Bonkovsky, Chihiro Morishima, Elizabeth C. Wright, Kristin K. Snow, Ann Stoddard. Patient mortality and liver transplantation during the HALT-C trial: Relationship to chronic liver disease and interferon therapy. Received Poster of Distinction Award. Raymond T. Chung, Adrian M. Di Bisceglie, Fred Poordad, Tarek Hassanein, Xiaolei Zhou, Ellen Lentz, Avi Prabhakar, Fayez M. Hamzeh. Association of host pharmacodynamic effects and virologic response to peginterferon alfa-2a/ribavirin in patients with chronic hepatitis C. Received Poster of Distinction Award. Andrew J. Muir, Adrian M. Di Bisceglie, Nathalie Adda, Michael P. Manns, Norah Terrault, Leif Bengtsson, Shelley George, John McHutchison. Improved sustained virologic response (SVR) in difficult-to-cure patients treated with Telaprevir (T) in combination with peginterferon alfa-2a (P) and ribavirin (R): An analysis from the PROVE3 study. Received Poster of Distinction Award. Sara Echelmeyer, Brennan M. Spiegel, Nabeel Koro, Fasiha Kanwal, Chun Xu. Very early endoscopy (EGD) for acute non-variceal upper GI tract hemorrhage: Sooner may not always be better. Sara Echelmeyer, Brennan M. Spiegel, Elliot Nelson, Charlene M. Prather, Nabeel Koro, Fasiha Kanwal. Does checking for orthostatic vital signs and performing rectal examination matter in patients with upper gastrointestinal hemorrhage? Fasiha Kanwal, Sara Echelmeyer, Nabeel Koro, Timothy Chrusciel, Brennan M. Spiegel. Variations in the process of care among patients with nonvariceal upper GI hemorrhage. Nabeel Koro, Yazan Abdalla, Fasiha Kanwal, Jay R. McDonald, Angelique L. Zeringue, rian K. Dieckgraefe. Risk factors for recurrent clostridium difficile-associated diarrhea: A retrospective case-control study. Fasiha Kanwal, Tuyen Hoang, Steven M. Asch, Jennifer R. Kramer, Angelique L. Zeringue, Hashem El-Serag. Over-utilization of hepatitis C antibody testing and its impact on quality of care in patients with chronic hepatitis C virus infection. Hashem El-Serag, Louise Henderson, Jennifer R. Kramer, Peter Richardson, Fasiha Kanwal, Jessica A. Davila. Utilization of surveillance for hepatocellular carcinoma among HCV infected patients in the United States. Received Poster of Distinction Award. Syed H. Tariq, Roshani J. Desai, John E. Morley, John T. Chibnall, Charlene M. Prather. Physicians; attitudes towards colorectal cancer screening in older adults. Received Poster of Distinction Award