1. A. B. C. D. 2. A. B. C. D. 3. A. B. C. D. 4. A. C. 5. A. B. C. D. 6. A. C. 7. A. B. C. D. 8. A. B. C.

The symptoms of retinol excess are bone fragility nausea weakness all of these Main function of insulin hormone is to increase glycogen in liver decrease glycogen in liver increase blood sugar decrease blood sugar Ascorbic acid acts as an reducing agent oxidizing agent oxidizing and reducing agent both none of the above A deficiency of thiamin produces the disease known as beri-beri B. scurvy cataract D. anemia Acyl carrier protein (ACP) plays an important role in the biosynthesis of fatty acids amino acids sugars carbohydrates Vitamin B12 (Cobalamin) is only synthesized by fishes B. micro-organisms plants D. animals Which of the following are reduced coenzymes? NADH and FADH2 NAD+ and FAD ATP and GTP Coenzyme A and ubiquinone The absence of ascorbic acid in the human diet gives rise to rickets pernicious anemia cataract

D. 9. A. B. C. D. 10. A. B. C. D. 11. A. B. C. D. 12. A. B. C. D. 13. A. C.

beri-beri Vitamins are essential because the organism can't synthesize these compounds at all can synthesize these compounds partially can't synthesize these compounds in the adequate amounts none of the above The prosthetic group biotin is a carrier of which type of molecule? Activated carbon dioxide (CO2) Ammonia Methyl group Sulfhydryl group Lipoic acid exists in oxidized form reduced form oxidized and reduced form both none of these Vitamin B12 is useful in the prevention and treatment of pernicious anemia scurvy cataract beri-beri An example of a digestive hormone is lipase B. pepsin amylase D. gastrin

14. In the co-enzyme B12the position occupied by a cyanide ion in vitamin B12 is bonded directly to the __________ of the ribose of adenosine. A. adenine B. 5-6 dimethylbenzimidazole C. hydroxycobalamin D. cyanocobalamin 15. The reductant, NADH, transfers the electrons via a flavo-proteins to the specific disulfide (S-S) protein to form a dithiol (SH,SH) protein which converts vitamin A. B12(Co2+)to B12(Co) B. B12(Co) to B12(Co2+) C. B12(Co2+)to B12(Co+)

D. 16. A. B. C. D. 17. A. B. C. D. 18. A. C. 19. A. B. C. D. 20. A. B. C. D.

B12(Co+)to B12(Co2+) An early sign of retinol deficiencies in man is night blindness keratinization xeropthalmia none of these An enzyme, L-folate reductase reduces folic acid to hydrofolic acid dihydrofolic acid trihydrofolic acid tetrahydrofolic acid What compound of raw egg white causes a syndrome similar to vitamin B deficiency? Avidin B. Betabindin Ovalbumin D. Albumin The disease Beriberi is due to a dietary deficiency in vitamin B1 (thiamine) vitamin B2 (riboflavin) vitamin B6 (pyridoxine) vitamin B12 Which of these is a symptom of vitamin A deficiency? Osteoporosis Impaired taste perception Blindness Impaired blood clotting

21. Vitamin-C is considered as a A.water soluble B. fat soluble C. fat and water soluble D.none of these 22. The vitamin niacin is part of the __________ molecule. A.ferredoxin B. pyridoxal phosphate C. pyrophosphate D.NAD+

23. Which of these hormones is a catecholamine? A.Follitropin B. Norepinephrine C. Tetraiodothyronine D.Tetrahydrofolate 24. Dihydroorotate dehydrogenase contains A.4 flavins and 4 atoms of iron per molecule B. 2 flavins and 4 atoms of iron per molecule C. 2 flavins and 2 atoms of iron per molecule D.4 flavins and 2 atoms of iron per molecule 25. E.coli ACP has its molecular weight as around A.9000 B. 19000 C. 39000 D.90,000 26. The vitamin riboflavin is part of the __________ molecule. A.ferredoxin B. FAD C. pyridoxal phosphat D.pyrophosphate 27. The most prominent role that tocopherol has in in-vitro systems is as a strong A.antioxidants B. reducing agent C. oxidizing agent D.all of these 28.Biotin occurs mainly in combined forms bound to protein through A.-N-lysine moiety B. -S-lysine moiety C. -N-biotinyl-L-lysine D.-N-lipoyl - L-lysine 29. Lipoic acid is a co-factor of the A.pyruvic dehydrogenase B. -ketoglutaric dehydrogenase C. both (a) and (b) D.di-hydroorotate dehydrogenase 30. -carotene together with -carotene, -carotene and cryptoxanthine are synthesized by A.plants B. animal C. plants and animals both D.none of these

31. Vitamin-D deficiency can cause A.rickets B. pernicious anemia C. cataract D.beri-beri 32. A deficiency of Vitamin K results in a decreased level of A.prothrombin B. thrombin C. fibrin D.fibrinogen 33. The vitamin riboflavin, which occurs as a yellow pigment in egg yolk and milk become A.colorless on reduction with Zn in acid and regained its color on re-oxidation B. colorless on oxidation and regained its color on reduction with Zn in acid C. more deep in color on reduction with Zn in acid and regained its color on re-oxidation D.more deep in color on oxidation and regained its color on reduction with Zn in acid 34. Which of the following compounds/(s) belong/(s) to the vitamin B6 group? A.Pyridoxal B. Pyridoxine C. Pyridoxamine D.All of these 35. What metal ion is specifically bound by vitamin B12? A.Cobalt B. Copper C. Zinc D.Iron 36. A fat-soluble vitamin that regulates blood clotting is A.vitamin A B. vitamin K C. vitamin C D.niacin 37. Which of these is a vitamin A precursor? A.Cobalamin C. Beta-Carotene

B. Pyridoxine D.Thiamine

38. In one iron-metalloflavoprotein, the iron is present as a A.heme-protein B. nonheme type C. both (a) and (b) D.flavin moiety 39. Vitamin K1 was first isolated from alfalalfa and has the phytyl side chain consisting of A.four isoprene units B. six isoprene units C. nine isoprene units

D.four isoprene units 40. Which of these molecules is vitamin H? A.Biotin B. Carnitine C. Folic acid D.None of these 41. The occurrence of metals such as iron or molybdenum in some flavoproteins can A.stabilize the semiquinone B. de-stabilize the semiquinone C. form chelation D.all of these 42. Models of end-linked Osaka VI Fibrinogen dimers, a bilayer dimer is linked at A.both ends by one disulfide bond B. either end via two disulfide bonds C. either end via a single disulfide bond D.both ends by two disulfide bonds 43. A deficiency of niacin causes A.pellagra C. cataract

B. scurvy D.anemia

44. Selenium is an essential component of the enzyme glutathione peroxidase which A.scavenges toxic hydoperoxycompounds in tissues B. reduces toxic hydoperoxycompounds in tissues C. oxidizes toxic hydoperoxycompounds in tissues D.none of the above 45. Who discovered vitamin C (ascorbic acid)? A.Paul Berg B. Linus Pauling C. Albert Szent-Gyorgyi D.Kerry Mull is