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CLASSIFICATION
MECHANISM OF ACTION Binds to B2adrenergic receptors in airway muscle leading to activation of adenylcyclase and increased levels of cyclic -3,5 adenosine monophosphate (cAMP) Increases in cAMP activate kinases which inhibit the phosphoylation of myosin and decreases intracellular calcium, relaxes smooth muscle airways Relaxation of airways, smooth muscle with subsequent bronchodilation
INDICATION
CONTRAINDICATIONS
SIDE EFFECTS
Salbutamol
Dosage: Patients dose: 1 nebule every 6 hours (6am12nn6pm12mn) Per nebulizer per t-tube to tracheo
Used as a bronchodilator to control and prevent reversible airway obstruction caused by asthma or Chronic Obstructive Pulmonary Disease Inhalation is used as a guide relief agent for acute bronchospasm and for exercise induced bronchospasm
Contraindicated in:
*Hypersensitivity to adrenergic amines
CNS: nervousness Restlessness Tremors Headache Insomnia CV: arrhythmias Hypertension Chest pain Palpitations Angina GI: nausea, vomiting Endo: Hyperglycemia Neuro: tremors F/E: hypokalemia
Assess lung sounds, pulse and blood pressure Assess and note color, amount, and consistency of sputum produced Assess for allergy
Observe for paradoxical bronchospasm (wheezing) Prepare a nebulising machine Check doctors orders Educate for the possible adverse effects
DURING:
Perform 15 right of medication monitor for paradoxical bronchospasm (wheezing) educate proper nebulization to clients Significant Others educated compliance of drug regimen educated to follow dose as recommended instruct client and significant others to report any untoward adverse reactions noted Document all relevant findings
AFTER: