Sample sent on: Jan 17, 13/ revised sample sent on Feb 1, 13 Sample Approved on : Jan 24, 13/

revised sample approved on Feb 5, 13 printer test sent on: 9th May printer test approved on : 20th May Printer : CTPS CIP: To come from MH Printer date: 8/16/2013 Copy editing : US Indexing: US Proof reading: US Section No Section Name Chapter No Chapter Name Front Matter Drug Invention and the Pharmaceutical Industry Pharmacokinetics: The Dynamics of Drug Absorption, Distribution, Metabolism, and Elimination Pharmacodynamics: Molecular Mechanisms of Drug Action Drug Toxicity and Poisoning Membrane Transporters and Drug Response Drug Metabolism Pharmacogenetics Neurotransmission: The Autonomic and Somatic Motor Nervous Systems Muscarinic Receptor Agonists and Antagonists Anticholinesterase Agents Agents Acting at the Neuromuscular Junction and Autonomic Ganglia Adrenergic Agonists and Antagonists -Hydroxytryptamine (Serotonin) and Dopamine Neurotransmission and the Central Nervous System

1 2 1 General Principles 3 4 5 6 7 8 9 10 11 12 13 14 2 Neuropharmacology

Drug Therapy of Depression and Anxiety Disorders 15 16 17 18 19 20 21 22 23 24 25 26 27 Pharmacotherapy of Psychosis and Mania Hypnotics and Sedatives Opioids, Analgesia, and Pain Management General Anesthetics and Therapeutic Gases Local Anesthetics Pharmacotherapy of the Epilepsies Treatment of Central Nervous System Degenerative Disorders Ethanol and Methanol Drug Addiction Regulation of Renal Function and Vascular Volume Renin and Angiotensin Treatment of Myocardial Ischemia and Hypertension

MODULATION OF CARDIOVASCULAR FUNCTION

MODULATION OF CARDIOVASCULAR FUNCTION

28 29 30 31 32 33

Inflammation, Immunomodulation, and Hematopoiesis

34 35 36 37 38 39 40 41 42 43 44 45

Hormones and Hormone Antagonists

Drugs Affecting Gastrointestinal Function

46

47 48 49 50

Pharmacotherapy of Congestive Heart Failure Anti-Arrhythmic Drugs Blood Coagulation and Anticoagulant, Fibrinolytic, and Antiplatelet Drugs Drug Therapy for Hypercholesterolemia and Dyslipidemia Histamine, Bradykinin, and Their Antagonists Lipid-Derived Autacoids: Eicosanoids and PlateletActivating Factor Pharmacotherapy of Inflammation, Fever, Pain, and Gout Immunosuppressants, Tolerogens, and Immunostimulants Pulmonary Pharmacology Hematopoietic Agents: Growth Factors, Minerals, and Vitamins Introduction To Endocrinology: The HypothalamicPituitary Axis Drugs Thyroid and Anti-Thyroid Estrogens and Progestins Androgens Pharmacology of the Adrenal Cortex Endocrine Pancreas and Pharmacotherapy of Diabetes Mellitus and Hypoglycemia Agents Affecting Mineral Ion Homeostasis and Bone Turnover Pharmacotherapy of Gastric Acidity, Peptic Ulcers, and Gastroesophageal Reflux Disease Treatment of Disorders of Bowel Motility and Water Flux; Anti-Emetics; Agents Used in Biliary and Pancreatic Disease Pharmacotherapy of Inflammatory Bowel Disease General Principles of Antimicrobial Therapy Chemotherapy of Malaria Chemotherapy of Protozoal Infections: Amebiasis, Giardiasis, Trichomoniasis, Trypanosomiasis, Leishmaniasis, and Other Protozoal Infections Chemotherapy of Helminth Infections Sulfonamides, Trimethoprim-Sulfamethoxazole, Quinolones, and Agents for Urinary Tract Infection Penicillins, Cephalosporins, and Other -Lactam Antibiotics Aminoglycosides Protein Synthesis Inhibitors and Miscellaneous Antibacterial Agents Chemotherapy of Tuberculosis, Mycobacterium Avium Complex Disease, and Leprosy Antifungal Agents Antiviral Agents (Nonretroviral) Antiretroviral Agents and Treatment of HIV Infection General Principles of Cancer Chemotherapy Cytotoxic Agents

51 52 Chemotherapy of Microbial Diseases

53 54 55 56 57 58 59 60 61

Chemotherapy of Neoplastic Diseases

Chemotherapy of Neoplastic Diseases

62 63 64

Targeted Therapies: Tyrosine Kinase Inhibitors, Monoclonal Antibodies, and Cytokines Natural Products in Cancer Chemotherapy: Hormones and Related Agents Ocular Pharmacology Dermatological Pharmacology Contraception and Pharmacotherapy of Obstetrical and Gynecological Disorders Environmental Toxicology: Carcinogens and Heavy Metals Appendix

Special Systems Pharmacology

65 66 67

Total

Beckywill be getting Permission Credit Lines. For Figures 3,4,5, & 7

11

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PR Received on 25-Feb 21-Jan

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EDITOR PREFERENCE SHEET EDITOR NAME SCHEDULE SHARED ON COMMENTS

Randa Hilal-Dandan

12/28/2012 Confirmed

Lawrence L. Brunton

12/28/2012 Confirmed

All Copy Edited chapters to be sent to editors for review

MODE OF DELIVERY

SHIPPING ADDRESS 12828 Harwick Lane, San Diego, CA 92130. Laurence Brunton 4489 Hermosa Way San Diego, CA 92103 PH 619-977-4667

EMAIL ADDRESS

E Proofs and hardcopy

rdandan@ucsd.edu

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lbrunton@ucsd.edu

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Schedule for BRUNTON Project

McGraw-Hill Production Manager: Richard Ruzycka Project Development Editor: Christie Naglieri Proofs Distribution: Editors + McGraw-Hill Arts Proof Distribution: Yes. To be sent to Editors for Review before placing the Arts in Pages. Compositor - Thomson XML: Yes Printer: CTPS Printer Date: Aug 16, 2013

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Remarks

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CE Schedule Due Date Sample Sample Batch 1 Batch 2 Batch 3 Batch 4 Chapter 1 and 2 Cahpter 26, 30 and 34 Chapter 3- 24 Chapter 25- 47 Chapter 48- 57 Chapter 58-67 Cast Off 2875 28-Dec 11-Jan 30-Jan 15-Feb 28-Feb 28-Feb Actual Date 28-Dec 11-Jan 1-Feb 15-Feb 26-Feb 1-Mar

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Estimated Cost $ 9
cost $729 $753 $975 $966 $1,158 $1,722 $1,224 $1,467 $72 $9,066

Estimated Cost $ 9000

Serial Number 1 2

Chapter Title Drug Invention and the Pharmaceutical Industry Drug Invention and the Pharmaceutical Industry Pharmacokinetics: The Dynamics of Drug Absorption, Distribution, Metabolism, and Elimination Pharmacokinetics: The Dynamics of Drug Absorption, Distribution, Metabolism, and Elimination Pharmacokinetics: The Dynamics of Drug Absorption, Distribution, Metabolism, and Elimination Pharmacokinetics: The Dynamics of Drug Absorption, Distribution, Metabolism, and Elimination Pharmacokinetics: The Dynamics of Drug Absorption, Distribution, Metabolism, and Elimination Pharmacokinetics: The Dynamics of Drug Absorption, Distribution, Metabolism, and Elimination Pharmacodynamics: Molecular Mechanisms of Drug Action Pharmacodynamics: Molecular Mechanisms of Drug Action Pharmacodynamics: Molecular Mechanisms of Drug Action Pharmacodynamics: Molecular Mechanisms of Drug Action Pharmacodynamics: Molecular Mechanisms of Drug Action Pharmacodynamics: Molecular Mechanisms of Drug Action Pharmacodynamics: Molecular Mechanisms of Drug Action Pharmacodynamics: Molecular Mechanisms of Drug Action Pharmacodynamics: Molecular Mechanisms of Drug Action

Chapter Number 1 1

NEW Fig No.

Art Sent to Editor on

1-1 1-2

21-Jan 21-Jan

2-1 21-Jan

2-2 21-Jan

2-3 A&B 21-Jan

2-4 A&B 21-Jan

2-5 21-Jan

2-6 21-Jan

9 10 11 12 13 14 15 16 17

3 3 3 3 3 3 3 3 3

3-1 3-2 3-3 3-4 3-5 3-6 3-7 3-8 3-9

21-Jan 21-Jan 21-Jan 21-Jan 21-Jan 21-Jan 21-Jan 21-Jan 21-Jan

18 19 20 21 22

Pharmacodynamics: Molecular Mechanisms of Drug Action Pharmacodynamics: Molecular Mechanisms of Drug Action Pharmacodynamics: Molecular Mechanisms of Drug Action Pharmacodynamics: Molecular Mechanisms of Drug Action Pharmacodynamics: Molecular Mechanisms of Drug Action Drug Toxicity and Poisoning Drug Drug Drug Drug Drug Toxicity Toxicity Toxicity Toxicity Toxicity and and and and and Poisoning Poisoning Poisoning Poisoning Poisoning and and and and and and and and and and

3 3 3 3 3

3-10 3-11 3-12 3-13 3-14

21-Jan 21-Jan 21-Jan 21-Jan 21-Jan 21-Jan 21-Jan 21-Jan 21-Jan 21-Jan 21-Jan 21-Jan 21-Jan 21-Jan 21-Jan 21-Jan 21-Jan 21-Jan 21-Jan 21-Jan 21-Jan 21-Jan 21-Jan 21-Jan 21-Jan 21-Jan 21-Jan 21-Jan 21-Jan 21-Jan 21-Jan 21-Jan 21-Jan 21-Jan 21-Jan

23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52

4 4 4 4 4 4 5 5 5 5 5 5 5 5 5 5 6 6 6 6 6 6 6 6 7 7 7 7 7 7

4-1 4-2 4-3 4-4 4-5A&B 4-6A&B 5-1 5-2 5-3 5-4 5-5 5-6 5-7 5-8 5-9 5-10 6-1 6-2 6-3 6-4 6-5 6-6 6-7 6-8 7-1 7-2 7-3 7-4 7-5 7-6

Membrane Transporters Drug Response Membrane Transporters Drug Response Membrane Transporters Drug Response Membrane Transporters Drug Response Membrane Transporters Drug Response Membrane Transporters Drug Response Membrane Transporters Drug Response Membrane Transporters Drug Response Membrane Transporters Drug Response Membrane Transporters Drug Response Drug Drug Drug Drug Drug Drug Drug Drug Metabolism Metabolism Metabolism Metabolism Metabolism Metabolism Metabolism Metabolism

Pharmacogenetics Pharmacogenetics Pharmacogenetics Pharmacogenetics Pharmacogenetics Pharmacogenetics

53 54 55 56 57 58 59

Neurotransmission: The Autonomic and Somatic Motor Nervous Systems Neurotransmission: The Autonomic and Somatic Motor Nervous Systems Neurotransmission: The Autonomic and Somatic Motor Nervous Systems Neurotransmission: The Autonomic and Somatic Motor Nervous Systems Neurotransmission: The Autonomic and Somatic Motor Nervous Systems Neurotransmission: The Autonomic and Somatic Motor Nervous Systems Neurotransmission: The Autonomic and Somatic Motor Nervous Systems Muscarinic Receptor Agonists and Antagonists Anticholinesterase Agents Anticholinesterase Agents Agents Acting at the Neuromuscular Junction and Autonomic Ganglia Agents Acting at the Neuromuscular Junction and Autonomic Ganglia Agents Acting at the Neuromuscular Junction and Autonomic Ganglia Agents Acting at the Neuromuscular Junction and Autonomic Ganglia Agents Acting at the Neuromuscular Junction and Autonomic Ganglia Adrenergic Agonists Antagonists Adrenergic Agonists Antagonists Adrenergic Agonists Antagonists Adrenergic Agonists Antagonists and and and and

8 8 8 8 8 8 8

8-1 8-2 8-3 8-4 8-5 8-6 8-7

21-Jan 21-Jan 21-Jan 21-Jan 21-Jan 21-Jan 21-Jan 21-Jan 21-Jan 21-Jan

60 61 62 68 69 70 71 72

9 10 10 11 11 11 11 11

9-1 10-1 UN 10-1A&B 11-1 11-2A&B 11-3 11-4 11-5

31-Jan 31-Jan 31-Jan 31-Jan 31-Jan 31-Jan 31-Jan 31-Jan 31-Jan 31-Jan 31-Jan 31-Jan 31-Jan

73 74 75 76 77 78 79 80

12 12 12 12 13 13 13 13

12-1 12-2 12-3 12-4 13-1 13-2 13-3 13-4

5-Hydroxytryptamine (Serotonin) and Dopamine 5-Hydroxytryptamine (Serotonin) and Dopamine 5-Hydroxytryptamine (Serotonin) and Dopamine 5-Hydroxytryptamine (Serotonin) and Dopamine

81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98

5-Hydroxytryptamine (Serotonin) and Dopamine 5-Hydroxytryptamine (Serotonin) and Dopamine 5-Hydroxytryptamine (Serotonin) and Dopamine Neurotransmission and the Central Nervous System Neurotransmission and the Central Nervous System Neurotransmission and the Central Nervous System Neurotransmission and the Central Nervous System Neurotransmission and the Central Nervous System Neurotransmission and the Central Nervous System Neurotransmission and the Central Nervous System Neurotransmission and the Central Nervous System Neurotransmission and the Central Nervous System Neurotransmission and the Central Nervous System Neurotransmission and the Central Nervous System Neurotransmission and the Central Nervous System Drug Therapy of Depression and Anxiety Disorders Pharmacotherapy of Psychosis and Mania Pharmacotherapy of Psychosis and Mania Hypnotics and Sedatives

13 13 13 14 14 14 14 14 14 14 14 14 14 14 14 15 16 16

13-5 13-6 13-7 14-1 14-2 14-3 14-4 14-5 14-6 14-7 14-8 14-9 14-10 14-11 14-12 15-1 16-1 16-2A&B THERE ARE NO FIGURES IN THIS CHAPTER. 18-1 18-2 18-3 18-4 18-5 19-1 19-2 19-3 19-4

31-Jan 31-Jan 31-Jan 31-Jan 31-Jan 31-Jan 31-Jan 31-Jan 31-Jan 31-Jan 31-Jan 31-Jan 31-Jan 31-Jan 31-Jan 31-Jan 31-Jan 31-Jan

17 18 18 18 18 18 19 19 19 19

99 100 101 102 103 104 105 106 107

Opioids, Analgesia, and Management Opioids, Analgesia, and Management Opioids, Analgesia, and Management Opioids, Analgesia, and Management Opioids, Analgesia, and Management

Pain Pain Pain Pain Pain

31-Jan 31-Jan 31-Jan 31-Jan 31-Jan 31-Jan 31-Jan 31-Jan 31-Jan

General Anesthetics and Therapeutic Gases General Anesthetics and Therapeutic Gases General Anesthetics and Therapeutic Gases General Anesthetics and Therapeutic Gases

108 109 110 111 112 113 114

General Anesthetics and Therapeutic Gases General Anesthetics and Therapeutic Gases Local Anesthetics Pharmacotherapy Epilepsies Pharmacotherapy Epilepsies Pharmacotherapy Epilepsies Pharmacotherapy Epilepsies of the of the of the of the

19 19 20 21 21 21 21

19-5 19-6 20-1 21-1 21-2 21-3 21-4

31-Jan 31-Jan 31-Jan 31-Jan 31-Jan 31-Jan 31-Jan

115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131

Treatment of Central Nervous System Degenerative Disorders Treatment of Central Nervous System Degenerative Disorders Treatment of Central Nervous System Degenerative Disorders Treatment of Central Nervous System Degenerative Disorders Treatment of Central Nervous System Degenerative Disorders Treatment of Central Nervous System Degenerative Disorders Ethanol and Methanol Drug Addiction Drug Addiction Drug Addiction Regulation of Renal Function and Vascular Volume Regulation of Renal Function and Vascular Volume Regulation of Renal Function and Vascular Volume Regulation of Renal Function and Vascular Volume Regulation of Renal Function and Vascular Volume Regulation of Renal Function and Vascular Volume Regulation of Renal Function and Vascular Volume

22 22 22 22 22 22 23 24 24 24 25 25 25 25 25 25 25

22-1 22-2 22-3 22-4 22-5 22-6 23-1 24-1 24-2 24-3 25-1 25-2 25-3 25-4 25-5 25-6 25-7

31-Jan 31-Jan 31-Jan 31-Jan 31-Jan 31-Jan 31-Jan 31-Jan 31-Jan 31-Jan

31-Jan 31-Jan 31-Jan 31-Jan 31-Jan 31-Jan 31-Jan

132 133 134 135 136 137 138 139 140 141 142 143

Regulation of Renal Function and Vascular Volume Regulation of Renal Function and Vascular Volume Regulation of Renal Function and Vascular Volume Regulation of Renal Function and Vascular Volume Regulation of Renal Function and Vascular Volume Regulation of Renal Function and Vascular Volume Regulation of Renal Function and Vascular Volume Regulation of Renal Function and Vascular Volume Regulation of Renal Function and Vascular Volume Regulation of Renal Function and Vascular Volume Regulation of Renal Function and Vascular Volume Regulation of Renal Function and Vascular Volume Renin and Angiotensin Renin and Angiotensin Renin and Angiotensin Renin and Angiotensin Renin and Angiotensin Renin and Angiotensin Renin and Angiotensin Treatment of Myocardial Ischemia and Hypertension Pharmacotherapy of Congestive Heart Failure Pharmacotherapy of Congestive Heart Failure Pharmacotherapy of Congestive Heart Failure Pharmacotherapy of Congestive Heart Failure Pharmacotherapy of Congestive Heart Failure

25 25 25 25 25 25 25 25 25 25 25 25

25-8 25-9 25-10 25-11 25-12 25-13 25-14 25-15 25-16 25-17 25-18 25-19

31-Jan 31-Jan 31-Jan 31-Jan 31-Jan 31-Jan 31-Jan 31-Jan 31-Jan 31-Jan 31-Jan 31-Jan 6-Feb 6-Feb 6-Feb 6-Feb 6-Feb 6-Feb 6-Feb 6-Feb 6-Feb 6-Feb 6-Feb 6-Feb 6-Feb

144 145 146 147 148 149 150 151 152 153 154 155 156

26 26 26 26 26 26 26 27 28 28 28 28 28

26-01 26-02 26-03 26-04 26-05 26-06 26-07 27-01 28-01 28-02 28-03 28-04 28-05

157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176 177

Pharmacotherapy of Congestive Heart Failure Pharmacotherapy of Congestive Heart Failure Pharmacotherapy of Congestive Heart Failure Anti-Arrhythmic Anti-Arrhythmic Anti-Arrhythmic Anti-Arrhythmic Anti-Arrhythmic Anti-Arrhythmic Anti-Arrhythmic Anti-Arrhythmic Anti-Arrhythmic Anti-Arrhythmic Anti-Arrhythmic Drugs Drugs Drugs Drugs Drugs Drugs Drugs Drugs Drugs Drugs Drugs and and and and and and and

28 28 28 29 29 29 29 29 29 29 29 29 29 29 30 30 30 30 30 30 30

28-06 28-07 28-08 29-1 29-2 29-3 29-4 29-5A&B 29-6A&B 29-7 29-8 29-9A-D 29-10A&B 29-11 30-1 30-2 30-3 30-4 30-5A-C 30-6 30-7

6-Feb 6-Feb 6-Feb 6-Feb 6-Feb 6-Feb 6-Feb 6-Feb 6-Feb 6-Feb 6-Feb 6-Feb 6-Feb 6-Feb

Blood Coagulation and Anticoagulant, Fibrinolytic, Antiplatelet Drugs Blood Coagulation and Anticoagulant, Fibrinolytic, Antiplatelet Drugs Blood Coagulation and Anticoagulant, Fibrinolytic, Antiplatelet Drugs Blood Coagulation and Anticoagulant, Fibrinolytic, Antiplatelet Drugs Blood Coagulation and Anticoagulant, Fibrinolytic, Antiplatelet Drugs Blood Coagulation and Anticoagulant, Fibrinolytic, Antiplatelet Drugs Blood Coagulation and Anticoagulant, Fibrinolytic, Antiplatelet Drugs

6-Feb 6-Feb 6-Feb 6-Feb 6-Feb 6-Feb 6-Feb

178 179

Drug Therapy for Hypercholesterolemia and Dyslipidemia Drug Therapy for Hypercholesterolemia and Dyslipidemia Histamine, Bradykinin, and Their Antagonists Histamine, Bradykinin, and Their Antagonists Histamine, Bradykinin, and Their Antagonists Lipid-Derived Autacoids: Eicosanoids and PlateletActivating Factor Lipid-Derived Autacoids: Eicosanoids and PlateletActivating Factor

31 31

31-1 31-2

6-Feb 6-Feb 6-Feb 6-Feb 6-Feb

180 181 182

32 32 32

32-1 32-2 32-3

183 184

33 33

33-1 33-2

6-Feb 6-Feb

185 186 187

Lipid-Derived Autacoids: Eicosanoids and PlateletActivating Factor Lipid-Derived Autacoids: Eicosanoids and PlateletActivating Factor Lipid-Derived Autacoids: Eicosanoids and PlateletActivating Factor Pharmacotherapy of Inflammation, Fever, Pain, and Gout Immunosuppressants, Tolerogens, and Immunostimulants Immunosuppressants, Tolerogens, and Immunostimulants Pulmonary Pharmacology Pulmonary Pharmacology Pulmonary Pharmacology Pulmonary Pharmacology Pulmonary Pulmonary Pulmonary Pulmonary Pulmonary Pulmonary Pulmonary Pharmacology Pharmacology Pharmacology Pharmacology Pharmacology Pharmacology Pharmacology

33 33 33

33-3 33-4 33-5

6-Feb 6-Feb 6-Feb

188

34

34-1

6-Feb

189 190 191 192 193 194 195 196 197 198 199 200 201 202 203 204 205 206 207 208 209 210

35 35 36 36 36 36 36 36 36 36 36 36 36 37 37 37 37 37 37 37 37 37

35-1 35-2 36-1 36-2 36-3 36-4 36-5 36-6 36-7 36-8 36-9 36-10 36-11 37-1 37-2 37-3 37-4 37-5 37-6 37-7 37-8 37-9

6-Feb 6-Feb 6-Feb 6-Feb 6-Feb 6-Feb 6-Feb 6-Feb 6-Feb 6-Feb 6-Feb 6-Feb 6-Feb

Hematopoietic Agents: Growth Factors, Minerals, and Vitamins Hematopoietic Agents: Growth Factors, Minerals, and Vitamins Hematopoietic Agents: Growth Factors, Minerals, and Vitamins Hematopoietic Agents: Growth Factors, Minerals, and Vitamins Hematopoietic Agents: Growth Factors, Minerals, and Vitamins Hematopoietic Agents: Growth Factors, Minerals, and Vitamins Hematopoietic Agents: Growth Factors, Minerals, and Vitamins Hematopoietic Agents: Growth Factors, Minerals, and Vitamins Hematopoietic Agents: Growth Factors, Minerals, and Vitamins

6-Feb 6-Feb 6-Feb 6-Feb 6-Feb 6-Feb 6-Feb 6-Feb 6-Feb

211 212 213 214 215 216

Introduction To Endocrinology: The Hypothalamic-Pituitary Axis Introduction To Endocrinology: The Hypothalamic-Pituitary Axis Introduction To Endocrinology: The Hypothalamic-Pituitary Axis Introduction To Endocrinology: The Hypothalamic-Pituitary Axis Introduction To Endocrinology: The Hypothalamic-Pituitary Axis Introduction To Endocrinology: The Hypothalamic-Pituitary Axis Thyroid and Anti-Thyroid Drugs Thyroid and Anti-Thyroid Drugs Thyroid and Anti-Thyroid Drugs Thyroid and Anti-Thyroid Drugs Thyroid and Anti-Thyroid Drugs Estrogens Estrogens Estrogens Estrogens and and and and Progestins Progestins Progestins Progestins

38 38 38 38 38 38

38-1 38-2 38-3 38-4 38-5 38-6

6-Feb 6-Feb 6-Feb 6-Feb 6-Feb 6-Feb 6-Feb 6-Feb 6-Feb 6-Feb 6-Feb 6-Feb 6-Feb 6-Feb 6-Feb 6-Feb 6-Feb 6-Feb 6-Feb 6-Feb 6-Feb 6-Feb 6-Feb 6-Feb 6-Feb 6-Feb

217 218 219 220 221 222 223 224 225 226 227 228 229 230 231 232 233 234 235 236

39 39 39 39 39 40 40 40 40 41 41 41 41 41

39-1 39-2 39-3 39-4 39-5 40-1 40-2 40-3A&B 40-4A-C 41-1 41-2 41-3 41-4 41-5A-C 42-1 42-2 42-3 42-4 42-5 42-6

Androgens Androgens Androgens Androgens Androgens Pharmacology of the Cortex Pharmacology of the Cortex Pharmacology of the Cortex Pharmacology of the Cortex Pharmacology of the Cortex Pharmacology of the Cortex Adrenal Adrenal Adrenal Adrenal Adrenal Adrenal

42 42 42 42 42 42

237

Endocrine Pancreas and Pharmacotherapy of Diabetes Mellitus and Hypoglycemia

43

43-1A&B 6-Feb

238

Endocrine Pancreas and Pharmacotherapy of Diabetes Mellitus and Hypoglycemia Endocrine Pancreas and Pharmacotherapy of Diabetes Mellitus and Hypoglycemia Endocrine Pancreas and Pharmacotherapy of Diabetes Mellitus and Hypoglycemia Endocrine Pancreas and Pharmacotherapy of Diabetes Mellitus and Hypoglycemia Endocrine Pancreas and Pharmacotherapy of Diabetes Mellitus and Hypoglycemia Endocrine Pancreas and Pharmacotherapy of Diabetes Mellitus and Hypoglycemia Endocrine Pancreas and Pharmacotherapy of Diabetes Mellitus and Hypoglycemia Endocrine Pancreas and Pharmacotherapy of Diabetes Mellitus and Hypoglycemia Endocrine Pancreas and Pharmacotherapy of Diabetes Mellitus and Hypoglycemia Endocrine Pancreas and Pharmacotherapy of Diabetes Mellitus and Hypoglycemia Agents Affecting Mineral Ion Homeostasis and Bone Turnover Agents Affecting Mineral Ion Homeostasis and Bone Turnover Agents Affecting Mineral Ion Homeostasis and Bone Turnover Agents Affecting Mineral Ion Homeostasis and Bone Turnover Agents Affecting Mineral Ion Homeostasis and Bone Turnover Agents Affecting Mineral Ion Homeostasis and Bone Turnover Agents Affecting Mineral Ion Homeostasis and Bone Turnover

43

43-2 6-Feb

239

43

43-3 6-Feb

240

43

43-4 6-Feb

241

43

43-5 6-Feb

242

43

43-6 6-Feb

243

43

43-7 6-Feb

244

43

43-8A-C 6-Feb

245

43

43-9 6-Feb

246

43

43-10 6-Feb

247

43

43-11 6-Feb

248 249 250 251 252 253 254

44 44 44 44 44 44 44

44-1 44-2 44-3 44-4 44-5 44-6 44-7

6-Feb 6-Feb 6-Feb 6-Feb 6-Feb 6-Feb 6-Feb

255

256

257

Pharmacotherapy of Gastric Acidity, Peptic Ulcers, and Gastroesophageal Reflux Disease Pharmacotherapy of Gastric Acidity, Peptic Ulcers, and Gastroesophageal Reflux Disease Pharmacotherapy of Gastric Acidity, Peptic Ulcers, and Gastroesophageal Reflux Disease Pharmacotherapy of Gastric Acidity, Peptic Ulcers, and Gastroesophageal Reflux Disease Treatment of Disorders of Bowel Motility and Water Flux; AntiEmetics; Agents Used in Biliary and Pancreatic Disease Treatment of Disorders of Bowel Motility and Water Flux; AntiEmetics; Agents Used in Biliary and Pancreatic Disease Treatment of Disorders of Bowel Motility and Water Flux; AntiEmetics; Agents Used in Biliary and Pancreatic Disease Treatment of Disorders of Bowel Motility and Water Flux; AntiEmetics; Agents Used in Biliary and Pancreatic Disease Pharmacotherapy of Inflammatory Bowel Disease Pharmacotherapy of Inflammatory Bowel Disease Pharmacotherapy of Inflammatory Bowel Disease Pharmacotherapy of Inflammatory Bowel Disease Pharmacotherapy of Inflammatory Bowel Disease General Principles of Antimicrobial Therapy General Principles of Antimicrobial Therapy General Principles of Antimicrobial Therapy

45

45-1 6-Feb

45

45-2 6-Feb

45

45-3 6-Feb

258

46

46-1 6-Feb

259

46

46-2 6-Feb

260

46

46-3 6-Feb

261

46

46-4 6-Feb

262

46

46-5 6-Feb

263 264 265 266 267

47 47 47 47 47

47-1 47-2 47-3 47-4 47-5

6-Feb 6-Feb 6-Feb 6-Feb 6-Feb 6-Feb 6-Feb 6-Feb

268 269 270

48 48 48

48-1 48-2 48-3A&B

271 272 273 274 275

General Principles of Antimicrobial Therapy General Principles of Antimicrobial Therapy Chemotherapy of Malaria Chemotherapy of Malaria Chemotherapy of Malaria Chemotherapy of Protozoal Infections: Amebiasis, Giardiasis, Trichomoniasis, Trypanosomiasis, Leishmaniasis, and Other Protozoal Infections

48 48 49 49 49

48-4A&B 48-5 49-1 49-2 49-3

6-Feb 6-Feb 6-Feb 6-Feb 6-Feb

50

THERE ARE NO FIGURES IN THIS CHAPTER.

276 277

Chemotherapy of Helminth Infections Chemotherapy of Helminth Infections Sulfonamides, TrimethoprimSulfamethoxazole, Quinolones, and Agents for Urinary Tract Infections Sulfonamides, TrimethoprimSulfamethoxazole, Quinolones, and Agents for Urinary Tract Infections Sulfonamides, TrimethoprimSulfamethoxazole, Quinolones, and Agents for Urinary Tract Infections Penicillins, Cephalosporins, and Other -Lactam Antibiotics Penicillins, Cephalosporins, and Other -Lactam Antibiotics Penicillins, Cephalosporins, and Other -Lactam Antibiotics Penicillins, Cephalosporins, and Other -Lactam Antibiotics Penicillins, Cephalosporins, and Other -Lactam Antibiotics Aminoglycosides Aminoglycosides Aminoglycosides Protein Synthesis Inhibitors and Miscellaneous Antibacterial Agents Protein Synthesis Inhibitors and Miscellaneous Antibacterial Agents

51 51

51-1 51-2

18-Feb 18-Feb

278

52

52-1 18-Feb

279

52

52-2 18-Feb

280

52

52-3 18-Feb

281 282 283 284 285 286 287 288

53 53 53 53 53 54 54 54

53-1 53-2 53-3 53-4 53-5 54-1 54-2 54-3

18-Feb 18-Feb 18-Feb 18-Feb 18-Feb 18-Feb 18-Feb 18-Feb

289 290

55 55

55-1 55-2

18-Feb 18-Feb

291 292

Protein Synthesis Inhibitors and Miscellaneous Antibacterial Agents Protein Synthesis Inhibitors and Miscellaneous Antibacterial Agents Chemotherapy of Tuberculosis, Mycobacterium Avium Complex Disease, and Leprosy Chemotherapy of Tuberculosis, Mycobacterium Avium Complex Disease, and Leprosy Chemotherapy of Tuberculosis, Mycobacterium Avium Complex Disease, and Leprosy Chemotherapy of Tuberculosis, Mycobacterium Avium Complex Disease, and Leprosy Chemotherapy of Tuberculosis, Mycobacterium Avium Complex Disease, and Leprosy Antifungal Agents Antifungal Agents Antifungal Agents Antiviral Agents (Nonretroviral) Antiviral Agents (Nonretroviral) Antiviral Agents (Nonretroviral) Antiviral Agents (Nonretroviral) Antiviral Agents (Nonretroviral) Antiviral Agents (Nonretroviral) Antiviral Agents (Nonretroviral) Antiviral Agents (Nonretroviral) Antiviral Agents (Nonretroviral) General Principles of Cancer Chemotherapy General Principles of Cancer Chemotherapy

55 55

55-3 55-4

18-Feb 18-Feb

293

56

56-1 18-Feb

294

56

56-2 18-Feb

295

56

56-3 18-Feb

296

56

56-4 18-Feb

297

56

56-5 18-Feb

298 299 300 301 302 303 304 305 306 307 308 309 310 311

57 57 57 58 58 58 59 59 59 59 59 59 60 60

57-1 57-2 57-3 58-1 58-2 58-3 59-1 59-2 59-3 59-4 59-5 59-6 60-1 60-2

18-Feb 18-Feb 18-Feb 18-Feb 18-Feb 18-Feb 18-Feb 18-Feb 18-Feb 18-Feb 18-Feb 18-Feb 18-Feb 18-Feb

312 313 314 315 316 317 318 319 320

Cytotoxic Cytotoxic Cytotoxic Cytotoxic Cytotoxic Cytotoxic Cytotoxic Cytotoxic Cytotoxic

Agents Agents Agents Agents Agents Agents Agents Agents Agents

61 61 61 61 61 61 61 61 61

61-1A&B 61-2 61-3 61-4A&B 61-5 61-6 61-7 61-8 61-9A&B

18-Feb 18-Feb 18-Feb 18-Feb 18-Feb 18-Feb 18-Feb 18-Feb 18-Feb

312

Targeted Therapies: Tyrosine Kinase Inhibitors, Monoclonal Antibodies, and Cytokines Targeted Therapies: Tyrosine Kinase Inhibitors, Monoclonal Antibodies, and Cytokines Targeted Therapies: Tyrosine Kinase Inhibitors, Monoclonal Antibodies, and Cytokines Natural Products in Cancer Chemotherapy: Hormones and Related Agents Natural Products in Cancer Chemotherapy: Hormones and Related Agents Natural Products in Cancer Chemotherapy: Hormones and Related Agents Ocular Ocular Ocular Ocular Ocular Ocular Ocular Pharmacology Pharmacology Pharmacology Pharmacology Pharmacology Pharmacology Pharmacology

62

62-1 18-Feb

313

62

62-2 18-Feb

314

62

62-3 18-Feb

315 316 317 318 319 320 321 322 323 324 325 326 327 328 329

63 63 63 64 64 64 64 64 64 64 65 65 65 65 65

63-1 63-2 63-3 64-1 64-2 64-3A&B 64-4 64-5 64-6 64-7 65-1 65-2 65-3 65-4 65-5

18-Feb 18-Feb 18-Feb 18-Feb 18-Feb 18-Feb 18-Feb 18-Feb 18-Feb 18-Feb 18-Feb 18-Feb 18-Feb 18-Feb 18-Feb

Dermatological Pharmacology Dermatological Pharmacology Dermatological Pharmacology Dermatological Pharmacology Dermatological Pharmacology Contraception and Pharmacotherapy of Obstetrical and Gynecological Disorders Contraception and Pharmacotherapy of Obstetrical and Gynecological Disorders

330

66

66-1A-C 18-Feb

331

66

66-2 18-Feb

332 333 334 335 336 337 338 339 340

Environmental Toxicology: Carcinogens and Heavy Metals Environmental Toxicology: Carcinogens and Heavy Metals Environmental Toxicology: Carcinogens and Heavy Metals Environmental Toxicology: Carcinogens and Heavy Metals Environmental Toxicology: Carcinogens and Heavy Metals Environmental Toxicology: Carcinogens and Heavy Metals Environmental Toxicology: Carcinogens and Heavy Metals Environmental Toxicology: Carcinogens and Heavy Metals Environmental Toxicology: Carcinogens and Heavy Metals Appendix I Principles of Prescription Order Writing and Patient Compliance

67 67 67 67 67 67 67 67 67

67-1 67-2 67-3 67-4 67-5 67-6 67-7 67-8 67-9

18-Feb 18-Feb 18-Feb 18-Feb 18-Feb 18-Feb 18-Feb 18-Feb 18-Feb

341

Appendix

A1-1

18-Feb

Comments

Revised arts sent to editor on

Comments on revised art from Editor

Remarks

Approved on 25 Jan Approved on 25 Jan

Approved on 25 Jan Changes mentioned on 25 Jan

29-Jan Approved on Feb 1

Approved on 25 Jan Changes mentioned on 25 Jan Changes mentioned on 25 Jan Changes mentioned on 25 Jan

29-Jan Approved on Feb 1

29-Jan Approved on Feb 1

29-Jan Approved on Feb 1

Approved on 6 feb Approved on 6 feb Approved on 6 feb Approved on 6 feb Approved on 6 feb Changes mentioned on 6 Feb Changes mentioned on 6 Feb Approved on 6 feb Approved on 6 feb 6-Feb 6-Feb

Approved on 6 feb Changes mentioned on 6 Feb Approved on 6 feb Approved on 6 feb Approved on 6 feb Changes 6 Feb Approved Approved Approved Approved Approved mentioned on on on on on on 6 6 6 6 6 feb feb feb feb feb 6-Feb 6-Feb

Approved on 20 March Approved on 20 March Approved on 20 March Approved on 20 March Changes mentioned on 20 March Approved on 20 March Approved on 20 March Approved on 20 March Approved on 20 March Changes mentioned on 20 March Approved Approved Approved Approved Approved Approved Approved Approved Approved Approved Approved Approved Approved Approved on on on on on on on on on on on on on on 14 14 14 14 14 14 14 14 14 14 14 14 14 14 March March March March March March March March March March March March March March

Approved on 20 March Approved on 20 March Approved on 20 March Approved on 20 March Approved on 20 March Approved on 20 March Changes mentioned on 20 March Approved on 14 March Approved on 8 April Approved on 8 April

Approved on 8 April Corrections given on 8April Corrections given on 8April Approved on 8 April Approved on 8 April Corrections given on 8April Approved on 8 April Approved on 8 April Corrections given on 8April Approved on 8 April Approved on 8 April Approved on 8 April Approved on 8 April

Corrections given on 8April Approved on 8 April Approved on 8 April Approved on 8 April Approved on 8 April Approved on 8 April Approved on 8 April Approved on 8 April Approved on 8 April Approved on 8 April Corrections given on 8April Approved on 8 April Approved on 8 April Approved on 8 April Approved on 8 April Approved on 8 April Corrections given on 8April Approved on 8 April

Corrections given on 8April Approved on 8 April Approved on 8 April Approved on 8 April Approved on 8 April Corrections given on 9April Approved on 9 April Approved on 9 April Approved on 9 April

Approved on 9 April Approved on 9 April Approved on 14 March coorection on 15-mar approved on 15-mar approved on 15-mar coorection on 15-mar

approved on 15-mar approved on 15-mar approved on 15-mar coorection on 15-mar approved on 15-mar approved on 15-mar approved on 16-mar approved on 16-mar approved on 16-mar approved on 16-mar corrections send on 17 March approved on 17-March approved on 17-March approved on 17-March approved on 17-March approved on 17-March approved on 17-March

approved on 17-March approved on 17-March approved on 17-March approved on 17-March approved on 17-March approved on 17-March corrections send on 17 March approved on 17-March approved on 17-March approved on 17-March approved on 17-March approved on 17-March Corrections given on 8April Approved on 8 April Approved on 8 April Approved on 8 April Corrections given on 8April Approved on 8 April Corrections given on 8April Approved on 17 March Approved on 18 March Correction on 18-March Correction on 18-March Correction on 18-March Approved on 18 March

Approved on 18 March Approved on 18 March Approved on 18 March Approved Approved Approved Approved Approved Approved Approved Approved Approved Approved Approved on on on on on on on on on on on 19 19 19 19 19 19 19 19 19 19 19 March March March March March March March March March March March

Approved on 8 April Approved on 8 April Approved on 8 April Approved on 8 April Corrections given on 8April Corrections given on 8April Corrections given on 8April

Approved on 19 March Approved on 19 March Corrections on 21March Approved on 21 March Approved on 21 March Corrections on 21March Approved on 21 March

Approved on 21 March Corrections on 21March Approved on 21 March Corrections given on 8April Corrections on 21March Corrections on 21March Approved on 21 March Corrections on 21March Approved on 21 March Corrections on 21March Approved on 21 March Approved on 21 March Approved on 21 March Approved on 21 March Approved on 21 March Approved on 21 March Approved on 21 March

Approved on 21 March Approved on 21 March Approved on 21 March Corrections on 21March Corrections on 21March Corrections on 21March Corrections on 21March Corrections on 21March Corrections on 21March

Approved on 22 March Approved on 22 March Approved on 22 March Approved on 22 March Corrections on 22March Approved on 22 March correction on 25 March Approved on 25 March correction on 25 March Approved on 25 March Approved on 25 March Approved Approved Approved Approved on on on on 25 25 25 25 March March March March

Approved on 25 March Approved on 25 March Approved on 25 March correction on 25 March Approved on 25 March Approved on 25 March Approved on 25 March Approved on 25 March Approved on 25 March Approved on 25 March Approved on 25 March

Approved on 25 March

Approved on 25 March

correction on 25 March

Approved on 25 March

Approved on 25 March

Approved on 25 March

Approved on 25 March

Approved on 25 March

Approved on 25 March

Approved on 25 March

correction on 25 March

Approved on 25 March Approved on 25 March Approved on 25 March correction on 25 March Approved on 25 March correction on 25 March correction on 25 March

Approved on 25 March

correction on 25 March

Approved on 25 March

Approved on 25 March

correction on 25 March

Approved on 25 March

correction on 25 March

Approved on 25 March

Approved on 25 March Approved on 25 March Approved on 25 March Approved on 25 March Approved on 25 March Approved on 25 March Approved on 25 March Approved on 25 March

Approved on 25 March correction on 25 March Approved on 26 March Approved on 26 March Approved on 26 March

Approved on 26 March Approved on 26 March

Approved on 26 March

Approved on 26 March

Approved on 26 March

Approved on 26 March Approved on 26 March Approved on 26 March Approved on 26 March Approved on 26 March Approved on 28-March Approved on 28-March Corrections on 28March

Approved on 28-March Approved on 28-March

Approved on 28-March Approved on 28-March

Approved on 28-March

Approved on 28-March

Corrections on 28March

Corrections on 28March

Approved on 28-March Approved on 28-March Corrections on 28March Approved on 28-March Approved on 28-March Approved on 28-March Approved on 28-March approved on 29-March approved on 29-March approved on 29-March approved on 29-March approved on 29-March approved on 29-March Approved on 28-March Corrections on 28March

Approved Approved Approved Approved Approved Approved Approved Approved Approved

on on on on on on on on on

1-April 1-April 1-April 1-April 1-April 1-April 1-April 1-April 1-April

Approved on 1-April

Approved on 1-April

Approved on 1-April

approved on 29-March Corrections on 29 march approved on 29-March approved approved approved approved approved approved approved on on on on on on on 29-March 29-March 29-March 29-March 29-March 29-March 29-March

approved on 29-March approved on 29-March approved on 29-March approved on 29-March approved on 29-March

Approved on 28-March

Approved on 28-March

Approved on 1-April corrections on 1 April Approved on 1-April Approved on 1-April Approved on 1-April Approved on 1-April Approved on 1-April Approved on 1-April Approved on 1-April

Approved on 9-April

Proof Reader

Julie

Revised schedule Chapters 5-9, 20-24 (approx 150 pages): 24 April - 27 April Chapters 25-47 (approx 440 pages): 7 May - 20 May Chapters 48-67+appendix (approx 360 pages): 31 May - 10 June

Chapter 19

Chapters 61-64 Chapters 65-67 Chapters 54,57, Appendix

Actual Chapters sent Chapter 2 Chapter 10 and 11 Chapter 12 Chapter 13 and 14 Chapter 1 and 15 Chapter 16, 17 and 26 Chapter 30 Chapter 3 Chapter 18 Chapter 4 Chapter 19

Actual Dates 18th Jan 8th feb 12th Feb 16th Feb 23rd feb 23rd feb 25th Feb 26th feb 27th Feb 3-Mar

Chapters received from PR 21st Jan 11th feb 13th feb 17th feb 25th Feb 25th Feb 28th feb 26th feb 27th Feb 28th feb 4-Mar

Chapters 61-64 Chapters 65-67 Chapters 54,57, Appendix

11th June 12th June 12th June 12th June

Batch

No of Pages

Hardcopy for Editor

Total No of Pages

Sent To

Sent On

Sent By

Batch 1 Batch 1 Batch2 Batch2 Batch 3 Batch 3

423 423 448 448

Yes Yes Yes Yes Yes Yes

423 423 448 448

Dr. Brunton Dr. Dandan Dr. Dandan Dr. Brunton Dr. Brunton Dr. Dandan

6-May-13 6-May-13 27-May-13 28-May-13 17-Jun 17-Jun

Saloni Saloni Saloni Saloni Saloni Saloni

Airway Bill No

Amount (INR)

3880668934 3880668945 1428071245 3264868633

Rs. 2183.7/Rs. 1890/-