West Visayas State University COLLEGE OF NURSING La Paz, Iloilo City

DRUG STUDY
Name of Patient:__________________________________ Age:__________ Dosage, Route, Frequency and Timing Dosage: 70mg/tab 1tab Ward/Bed Number:__________ Attending Physician:_______________________________ Impression/ Diagnosis:______________________________

Name of Drug Generic: sultamicillin tosylate Brand: Unasyn

Mechanism of Action Sulbactam is a semisynthetic betalactamase inhibitor which, in combination with ampicillin, extends the antibacterial activity of the latter to include some beta-lactamase-producing strains of bacteria that would otherwise be resistant
*Karch, Amy M. 201 Lippicotts nursing drug guide *Deglin, J., vallerand,A., davissDrug Guide for nurses 11th Edition. *Nursing Spectrum Drug handbook 2010 5th edition

Indication For infections caused by susceptible microorganisms: Intraabdominal infections, UTIs, skin and soft tissue infections

Adverse Reactions GI: melena, enterocolitis pseudomembranous colitis, black hairy tongue, stomatitis, glossitis CNS; (rare)Convulsions, seizures Hema:anemia, thrombophlebitis Resp.: apnea Side Effects CNS:dizziness GI:diarrhea/loose stool, nausea/vomiting epigastric distress, abd. Cramps/pain Resp. dyspnea

Special Precautions Renal Impairment or severe renal insufficiency Epstein-Barr Virus infection Cytomegalovirus infection Infectious mononucleosis

Nursing Responsibilities
* Instruct patient to immediately report signs and symptoms of hypersensitivity reaction, such as rash, fever, or chills. * Advise patient to minimize GI upset by eating small, frequent servings of food and drinking plenty of fluids. * Inform patient that drug lowers resistance to certain infections. Instruct him to report new signs or symptoms of infection, especially in mouth or rectum.Tell patient to promptly report unusual bleeding or bruising. *Instruct patient to avoid activities that can cause injury. Advise him to use soft toothbrush and electric razor to avoid gum and skin injury.

Route:PO

Frequency:BID Classification Functional: Antibacterial Chemical: Aminopenicillin Beta-Lactamase inhibitor Timing:8 6

Contraindications History of allergic reactions to penicillins

Student's Name:__________________________________________ Clinical Instructor:________________________________________ West Visayas State University

COLLEGE OF NURSING La Paz, Iloilo City

DRUG STUDY
Name of Patient:__________________________________ Age:__________ Dosage, Route, Frequency and Timing Dosage: 30mg/kg/day 2caps Ward/Bed Number:__________ Attending Physician:_______________________________ Impression/ Diagnosis:______________________________

Name of Drug Generic: hydroxyurea Brand: Krabinex

Mechanism of Action

Indication

Adverse Reactions Bone marrow suppression, megaloblastosis, infertility, tubular dysfunction, leukopenia

Special Precautions Impaired renal or hepatic function

Nursing Responsibilities
*Assess allergies to hydroxyurea, as well as renal or hepatic function *Be aware of precautionary measures of handling such antineoplastic drug(may be carcinogenic) *Instruct patient not to chew, crush, or chew the drug

Route: PO Classification Functional: Anti neoplastic Chemical: antimetabolites Frequency: TID

It has a cytotoxic effect For myelogenous inhibiting an enzyme that leukemia is crucial for DNA synthesis. It takes the place of normal protein thus inhibiting growth of cancer cells.
*Nursing spectrum Drug handbook 2010. 5th Edition. P. 557-559

Contraindications Hypersensitivity to hydroxyurea and in severe bone marrow suppression

Side Effects Headache, dizziness, disorientation, maculopapular rash, stomatitis, anorexia, vomiting, diarrhea, constipation, fever, chills, malaise

*Inspect oral mucosa for erythema and ulcerations; and instruct to use a softbristled toothbrush to prevent bleeding of gums. *Educate patient about maintenance of frequent small meals and maintenance of good nutrition and hydration(2-3L of fluid) *Instruct to report about fever, chills, sore throat, unusual bleeding or bruising, severe nausea, vomiting, loss of appetite and mouth sores and thus prompt interventions can be done

Timing: 8 1 6

Student's Name:__________________________________________ Clinical Instructor:________________________________________ West Visayas State University

COLLEGE OF NURSING La Paz, Iloilo City

DRUG STUDY
Name of Patient:__________________________________ Age:__________ Dosage, Route, Frequency and Timing Dosage: 500mg/tab 1 tab Ward/Bed Number:__________ Attending Physician:_______________________________ Impression/ Diagnosis:______________________________

Name of Drug Generic: paracetamol Brand: Biogesic

Mechanism of Action

Indication Treatment of fever/hyperthermia

Adverse Reactions

Special Precautions

Nursing Responsibilities *Assess allergy, renal and hepatic function, *Observe for acute toxicity and overdose. * Tell patient, parents, or other caregivers not to use drug concurrently with other acetaminophen-containing Products to avoid overdose and/or toxicity *Aware the patient that there is increased risk of hepatotoxicity with alcohol, thus instruct to avoid drinking alcoholic beverages

Classification Functional: Antipyretics Chemical: Non-opioid analgesic

Unclear. Pain relief may result from inhibition of prostaglandin synthesis in CNS, with subsequent blockage of pain Route: PO impulses. Fever reduction may result from vasodilation and increased Frequency: PRN peripheral blood flow in hypothalamus, which Timing: Q4H for dissipates heat and lowers T=37.8C and body temperature.
*Karch, Amy M. 201 Lippicotts nursing drug guide *Deglin, J., vallerand,A., davissDrug Guide for nurses 11th Edition. *Nursing Spectrum Drug handbook 2010 5th edition P 14-15

CV: myocardial damage Anemia Hema: thrombocytopenia, Renal and Hepatic hemolytic disease anemia, neutropenia, leukopenia, pancytopenia Hepatic: hepatotoxicity, renal failure Metabolic: hypoglycemic coma Side Effects CNS: headache CV: chest pain Resp: Dyspnea Meta: hypoglycemia GU: hematuria, anuria GI:abd. pain Hepatic: jaundice Skin: rash, urticaria Other: hypersensitivity reactions (such as fever)

Contraindications Hypersensitivy Alcohol use

Student's Name:__________________________________________ Clinical Instructor:________________________________________ West Visayas State University

COLLEGE OF NURSING La Paz, Iloilo City

DRUG STUDY
Name of Patient:__________________________________ Age:__________ Dosage, Route, Frequency and Timing Dosage: 5cc Ward/Bed Number:__________ Attending Physician:_______________________________ Impression/ Diagnosis:______________________________

Name of Drug Generic: Nystatin Brand:

Mechanism of Action

Indication Oral/oropharyngeal candidiasis and GI infection

Adverse Reactions

Special Precautions renal or hepatic disease, achlorhydria denture wearers(require soaking)

Nursing Responsibilities *if patient missed a dose, instruct to take dose as soon as possible but not if almost time for next schedule, and then resume his regular dosing schedule *patient should hold suspension in mouth before swallowing, then gargle or swish and swallow *increased irritation of mucous membranes may indicate the need to discontinue medication

Classification Functional: antiinfective Chemical: antifungal

Fungistatic/fungicidal: Binds to fungal cell membrane allowing leakage of cellular Route: PO(swish contents. and swallow) Interferes with fungal cell-wall synthesis, inhibiting formation of ergo sterols, increasing Frequency: TID cell-wall permeability, and causing osmotic instability. Timing: 8 1 6
*Deglin, J., vallerand,A., davissDrug Guide for nurses 11th Edition. *Nursing Spectrum Drug handbook 2010 5th edition

Contraindications Hypersensitivity(some products may contain ethyl or benzyl alcohol)-avoid use in patients who are hypersensitive or intolerant of these additives)

Side Effects GI: nausea, vomiting, diarrhea, GI distress, oral irritation(large doses)

Student's Name:__________________________________________ Clinical Instructor:________________________________________