Beruflich Dokumente
Kultur Dokumente
)
Chlamydia trachomatis persistence: An Update. (2003)
Mpiga, P., & Ravaoarinoro, M.
pp 9-19.
World Health Organization; UNAIDS. (2012).
p 10-11
p.11
Chlamydial persistence refers to C. trachomatis possibly being in an atypical, intracellular and
metabolically less active state that is difficult to resolve not only by the host-defence system, but
also by antibiotherapy.
p.11
Therapy and Therapeutic Failure
Chlamydia trachomatis infections are resolved by treatment with antibiotics that are able to pass
through lipophilic plasma membranes to reach the RBs which are metabolically active and so most
susceptible to treatment.
B.)
Chlamydia trachomatis infections. In Strategies and laboratory methods for
strengthening surveillance of sexually transmitted infections
pp. 6-7
Geneva: WHO Press.
p.6
Chlamydia trachomatis infection is reported as the most prevalent sexually transmitted bacterial
infection worldwide, with an annual estimate of 105.7 million new cases worldwide. Chlamydial
infection is common among sexually active young men and women. If left untreated, it can lead to
complications, including endometritis, salpingitis, pelvic inflammatory disease, chronic pelvic pain
and ectopic pregnancy in women, reduced fertility in both men and women, and neonatal infections
such as ophthalmia neonatorum and pneumonia.
p.7
High rates of rectal chlamydial infection have been reported among MSM (men who have sex with
men) in the Philippines (9.2%) <- (parang hindi ko na ata Kilangan isama to?)
C.)
http://www.cdc.gov/std/stats10/adol.htm
1.) Weinstock H, Berman S, Cates W Jr. Sexually transmitted diseases among American
youth: incidence and prevalence estimates, 2000. Perspect Sex Reprod Health.
2004:36(1):6-10.
2.) DiClemente RJ, Salazar LF, Crosby RA. A review of STD/HIV preventive interventions
for adolescents: sustaining effects using an ecological approach. J. Pediatr. Psychol.
2007;32 (8): 888-906.
3.) Sieving RE, Bernat DH, Resnick MD, Oliphant J, Pettingell S, Plowman S, et al. A
clinic-based youth development program to reduce sexual risk behaviors among
adolescent girls: prime time pilot study. Health Promot Pract (online). May 23, 2011.
4.) Upchurch DM, Mason W, Kusunoki Y, Kriechbaum MJ. Social and behavioral
determinants of self-reported STD among adolescents. Perspect Sex Reprod Health.
2004;36(6):276-287.
5.) Satterwhite CL, Tian LH, Braxton J, Weinstock H. Chlamydia prevalence among
women and men entering the National Job Training Program: United States, 2003
2007. Sex Transm Dis. 2010;37(2):63-7.
Estimates suggest that even though young people aged 1524 years represent only
25% of the sexually experienced population, they acquire nearly half of all new STDs
200
6
200
7
Cases of Chlamydia
Rates*
Total
Male
Femal
e
Unknown
Sex
Total
Male Femal
e
10-14
13,542
1,227
12,279
36
65.7
11.6
15-19
802
20-24
729
25-29
309
774.6
462.7 1,097.
5
30-34
128
322.2
224.2
421.5
35-39
74
145.4
118.8
171.5
40-44
15,251
7,350
7,870
31
67.8
65.6
69.8
45-54
11,293
5,767
5,495
31
26.1
27.1
25.0
55-64
2,398
1,323
1,070
7.6
8.7
6.5
65+
889
420
465
2.4
2.7
2.2
Unknown
Age
4,789
1,444
3,009
336
10-14
13,583
1,242
12,303
38
66.9
11.9
124.1
15-19
827
20-24
698
25-29
282
827.2
506.3 1,160.
9
30-34
135
354.1
247.1
462.8
35-39
75
158.3
129.0
187.3
40-44
16,554
7,941
8,580
33
75.3
72.4
77.9
45-54
13,091
6,835
6,226
30
29.8
31.7
27.9
55-64
2,831
1,521
1,304
8.7
9.6
7.7
122.0
Unknown
Sex
200
8
200
9
201
0
65+
809
413
392
2.1
2.6
1.8
Unknown
Age
3,920
1,168
2,510
242
10-14
14,297
1,441
12,816
40
71.3
14.0
130.9
15-19
1,310
20-24
1,161
25-29
503
881.4
554.1 1,221.
0
30-34
240
381.4
268.5
495.5
35-39
119
174.0
141.1
206.3
40-44
17,991
8,525
9,398
68
83.7
79.3
87.3
45-54
14,271
7,386
6,832
53
32.2
33.8
30.3
55-64
3,064
1,634
1,424
9.1
10.1
8.2
65+
887
427
453
2.3
2.6
2.0
Unknown
Age
3,168
939
2,003
226
10-14
13,899
1,405
12,447
47
69.6
13.7
127.6
15-19
851
20-24
839
25-29
336
878.7
561.7 1,209.
1
30-34
159
390.2
280.4
502.0
35-39
73
176.7
143.5
209.7
40-44
18,263
8,750
9,467
46
87.0
83.3
90.3
45-54
15,033
7,818
7,183
32
33.7
35.6
31.8
55-64
3,365
1,787
1,573
9.7
10.6
8.7
65+
946
472
471
2.4
2.8
2.1
Unknown
Age
3,159
839
2,039
281
10-14
14,531
1,590
12,860
81
72.8
15.6
131.9
15-19
1,520
20-24
1,316
25-29
494
911.2
598.0 1,236.
1
30-34
253
419.4
309.0
530.9
35-39
102
186.9
153.2
220.1
40-44
19,614
9,594
9,931
89
93.4
91.3
94.7
45-54
16,106
8,635
7,423
48
36.1
39.3
32.8
55-64
3,523
1,834
1,674
15
10.1
10.9
9.3
65+
954
464
481
2.4
2.8
2.1
Unknown
Age
2,358
636
1,503
219
D.
Fantasia, H. C., Fontenot, H., Sutherland, M., & Harris, A. (2011).
Sexually Transmitted Infections in Women: An Overview.
CNE Journal
p48-50.
Sexually transmitted infections (STIs) continue to be a major public health concern and a
significant source of morbidity. The numbers are staggering. It is estimated that there are
approximately 19 million new STI cases each year. Of these, al- most half occur in young people
between the ages of 15 and 24 (Weinstock, Berman, & Cates, 2004).
Chlamydia can be transmitted during vaginal, anal or oral sex. Symptoms are usually mild or
absent, so women are often unaware of their infection. Chlamydia is often referred to as a silent
disease because the majority of infected individuals have no symptoms.