Host Interface Manual - U411 PDF

Roche Diagnostics AG
cobas u 411
Host Interface Manual
Version 2.1
cobas u 411 Host Interface Manual
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cobas u 411
Host
DISCLAIMER
ROCHE DIAGNOSTICS MAKES NO REPRESENTATIONS OR WARRANTIES WITH RESPECT

TO THE CONTENTS OF THIS DOCUMENT AND SPECIFICALLY DISCLAIMS ANY IMPLIED
WARRANTIES, INCLUDING THE IMPLIED WARRANTIES OF MERCHANTABILITY AND
FITNESS FOR A PARTICULAR PURPOSE. IN NO CASE SHALL ROCHE DIAGNOSTICS BE
LIABLE FOR INCIDENTAL OR CONSEQUENTIAL DAMAGES.
COPYRIGHT
COPYRIGHT 2011, BY ROCHE DIAGNOSTICS. ALL RIGHTS RESERVED. NO PART OF THIS

PUBLICATION MAY BE REPRODUCED WITHOUT THE EXPRESS WRITTEN PERMISSION OF
ROCHE DIAGNOSTICS.
VERSION HISTORY
Version
1.0
1.1
Date
Mar-2007
Oct-2008
Software version
3.0
3.0.4.0801
2.0
Apr-2010
3.1.0.0901
2.1
May-2011
3.2.0.1001
Modifications
-First Release
-Implementation of US ranges
-Interface chapter 3 revised
-Further Help chapter 1.4 revised General bug fixing
-Implementation of Reference ranges
-Message Header Record chapter revised
-General wording corrections
-General wording corrections
-Chapter Introduction and Purpose rewritten
-Chapter Supported Host Protocols moved
-Chapter Size of Sample ID moved
-Chapter Flags created
-Chapter Transmitted Date moved and rewritten
-Chapter Host Interface Configuration rewritten
-Chapter Error Handling rewritten
-Chapter Sediment Result Record removed
-Result Record no. 9 modified
-All examples updated
-Reference ranges removed
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1 Purpose .......................................................................................................................................4
1.1 Document structure ..............................................................................................................4
1.2 Audience...............................................................................................................................4
1.3 Related documents...............................................................................................................4
1.4 Used syntax and abbreviations.............................................................................................4
1.5 Support .................................................................................................................................5
2 Introduction ................................................................................................................................6
2.1 Overview cobas u 411 analyzer............................................................................................6
2.2 Supported host protocols......................................................................................................6
2.3 Sample ID length ..................................................................................................................6
2.4 Flags .....................................................................................................................................6
2.5 Upload (cobas u 411 to host system) ...................................................................................8
2.6 Arbitrary units........................................................................................................................9
2.7 Download data (host system to cobas u 411).....................................................................10
3 Host interface configuration ...................................................................................................10
3.1 Communication settings .....................................................................................................10
3.2 Host interface behaviour.....................................................................................................10
3.3 Serial cable .........................................................................................................................11
4 Error handling (behaviour of a failed transmission).............................................................11
5 Description of the supported protocols.................................................................................12
5.1 ASTM plus protocol ............................................................................................................12
5.1.1 General .......................................................................................................................12
5.1.2 Communication startup ...............................................................................................13
5.1.3 Record description ......................................................................................................14
5.1.4 ASTM plus trace file examples....................................................................................20
5.2 ASTM Urisys 2400 protocol ................................................................................................35
5.2.1 General .......................................................................................................................35
5.2.2 Communication structure ............................................................................................37
5.2.3 Record descriptions ....................................................................................................38
5.2.4 ASTM Urisys 2400 trace file examples .......................................................................44
6 Appendices ...............................................................................................................................49
6.1 Appendix 1: ASCII-table .....................................................................................................49
6.2 Appendix 2: Definition of test codes and test numbers (for ASTM plus protocol
only) ..........................................................................................................................................50
6.3 Appendix 3: Printouts of control and sample results...........................................................51
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1 Purpose
The purpose of this document is to describe the host interface specifications of the cobas u 411
analyzer. These specifications define the hardware and software settings and the data interchange
via null modem cable (RS-232) between the cobas u 411 and the host system.
1.1 Document structure

This document is structured in a general part for all supported host protocols (chapter 2 to 4) and a
protocol specific part (chapter 5).
The general part contains information about host interface configuration, cable wiring, brief
overview about the different supported host protocols, description of flags and error handling.
The protocol specific part contains a sub-chapter for each supported host protocol, in which the
communication structure and the records are described. There is a detailed example for a
better comprehension, at the end of each record description. The whole trace files of different
data interchanges are added at the end of the corresponding protocol description.
There are additional information in the chapter appendices, such as ASCII-Table, Definition of Test
Codes and Test Numbers for ASTM plus and the printouts of the different Control and Sample
Results used in the examples.
1.2 Audience
This document is written for engineers who must configure the cobas u 411 host interface in the
environment of a laboratory. Depending on the type of host system and on the work flow in the
laboratory the cobas u 411 host interface offers a set of configurable features.
1.3 Related documents

Related documents:
[1]
Roche Diagnostics ASTM plus interface specification version 2.0
[2]
E 1394-91 standard specification for transferring information between clinical
instruments and computer systems, American Society for Testing and Materials
(ASTM)
1.4 Used syntax and abbreviations

Used Syntax
<SpecimenID>
char
text
pos_int
d_t
date
Meaning any string (not containing delimiters), representing a

value of the ASTM field SpecimenID.
Single character. Content specified by standard.
String. Variable length.
Positive integer (0 to 65535)
Date and time format as specified by ASTM
(YYYYMMDDHHMMSS)
Date format as specified by ASTM (YYYYMMDD)
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Terms
ASTM
LIS
Host
American Society for Testing and Materials

Laboratory Information System (host system)
1.5 Support
In case of questions please contact your local Roche Diagnostics Service Department, or
alternatively the Global Customer Support:
E-Mail address:
rotkreuz.gsscdiric@roche.com
Clarify queue:
GSSCDIRIC
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2 Introduction
The purpose of this document is to describe the host interface specifications of the cobas u 411
analyzer. These specifications define the hardware and software settings and the data interchange
via null modem cable (RS-232) between the cobas u 411 and the host system.
2.1 Overview cobas u 411 analyzer

The cobas u 411 analyzer is a semiautomatic urinalysis system intended for in vitro qualitative or
semi-quantitative determination of urine analytes, including specific gravity (SG), pH, leukocytes,
nitrite, protein, glucose, ketones, urobilinogen, bilirubin, erythrocytes and color.
2.2 Supported host protocols

The cobas u 411 analyzer supports the following host protocols:
ASTM plus
ASTM Urisys 2400
2.3 Sample ID length

The cobas u 411 analyzer supports a sample ID with a maximum length of 13 characters.
2.4 Flags
The result data which is transmitted to the host system (or printed) must be checked for flags.
There can be different flags, which are sent in a Comment Record additionally to the Result
Record or in the Result Record itself, using the ASTM plus or ASTM Urisys 2400 protocols. On the
printout, the flags are next to the data. The meaning of the flags is listed below.
Attention:
Flags are in order to bring some of the values to attention of the operator. Therefore
it is important that these flags are displayed on the host system. If these flags are
not displayed, this could mislead the operator to wrong conclusions and medical
decisions!
Result flags
Flag
S
*
Result flags
Sieve
Abnormal
Changed reflectance
value
Edited result
Explanation
Test parameter result corresponds to sieve criteria settings
For patient sample test parameter result corresponds to
abnormal criteria settings
Initial range table is changed
Data has been edited
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Sample flags
Flag
T
Sample flags
Test strip
Calibration exceeded
Explanation
Error during measurement of test strip or reference strip.
Possible reasons:
Strip upside down
Strip incompletely wet
Strip completely dry
Strip missing or wrong positioning
Calculation not possible
Calibration interval of four weeks is exceeded
Control flags
Flag
S
*
T
Control flags
Sieve
Abnormal
Test strip
Calibration exceeded
Explanation
Test parameter result corresponds to sieve criteria settings
For control sample it means out of range
Error during measurement of test strip or a reference strip.
Possible reasons:
Strip upside down
Calibration interval of four weeks is exceeded
Additional flags for ASTM Urisys 2400 protocol only

Flag
R
Sample flags
Test strip error
Order cannot be done
Explanation
Error during measurement of test strip or reference strip.
Possible reasons:
Strip upside down
Usually in combination with the R flag
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Transmitted Data
The cobas u 411 analyzer always initiates the communication to the host system. Hence, the
cobas u 411 analyzer is the master and the host system the slave.
2.5 Upload (cobas u 411 to host system)
Sample ID / Sequence number

Date and time of calculation
Strip results
Units
Flags
Color and clarity of sample
Sediment results
compensated raw data (optional)
Instrument ID / serial no.
User ID
Software version
Range table (boundary setting)
Test strip lot number
Test strip expiry date
Calibration strip lot number
Calibration strip expiry date
Legend:
Note:
Supported
ASTM Urisys 2400
ASTM plus
Protocol
ASTM Urisys 2400

-
Data
Control Result
Strip Result
Data
ASTM plus
Protocol
Depending on the selected host protocol, different data is sent to the host system. The tables
below give an overview about the different protocols and their transmitted data.
Name and lot ID

Control results for three levels
Units
Flags
Color
compensated raw data (optional)
Instrument ID / serial no.
User ID
Software version
Range table (boundary setting)
Control lot number
Control name
Control expiry date
- not supported
There are two different names for the same type of protocol, depending on which
analyzer is in use:
Using the Urisys 1800 analyzer, the protocol is called "Urisys 2400"
Using the cobas u 411 analyzer, the protocol is called "ASTM Urisys 2400".
Within this document the name ASTM Urisys 2400 for cobas u 411 is used.
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ASTM plus protocol

Strip Results
Strip results
Units
Flags
Sediment results
Compensated raw data (optional)
Instrument ID
User ID
Software version
Range tables (boundary setting)
ASTM Urisys 2400

Strip Results
Strip results
Units
Flags
Instrument ID
User ID
Software version
Host
Control Results
Name and lot ID
Date and time of control calculation
Units
Flags
Color
Instrument ID
User ID
Software version
Range tables (boundary setting)
Control lot number
Control name
Control expiry date
Control Results
Name and lot ID
Date and time of control calculation
Units
Flags
Color
Instrument ID
User ID
Software version
Control lot number
Control name
2.6 Arbitrary units

ASTM plus
Arbitrary units are sent to the host system in combination with other units (Conventional or SI).
With the control results, the preset arbitrary values (default) are transmitted.
ASTM Urisys 2400
Arbitrary units are sent to the host system only when they are selected separately and not in
combination with other units (Conventional or SI).
With the control results, the preset arbitrary values (default) are transmitted.
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2.7 Download data (host system to cobas u 411)

The data download from the host system to the analyzer is performed on the cobas u 411 by
clicking the <Download> button. The following data can be transmitted from the host system to the
cobas u 411: Worklist (list of sample IDs)
Note: The Urisys 2400 protocol does not support this mode.
3 Host interface configuration

The communication between the cobas u 411 analyzer and the host system is established using a
serial asynchronous interface cable. The communication settings must be equal on both sides
(cobas u 411 and host system), see chapter 3.1 below.
3.1 Communication settings

The host settings on the cobas u 411 analyzer are set to OFF by default. To establish the host
communication, the host settings must be set to ON. Changes in the cobas u 411 analyzer
communication parameters are only possible if the host settings are set to OFF. To configure the
host settings and to enable the host communication, go to the configuration menu: Utilities >
System Parameters > Host Comm.
The following host communication settings are configurable in the cobas u 411 analyzer user
interface.
Configuration
Specification
Default
Baud rate
1200, 2400, 4800, 9600, 19200, 38400, 57600
9600
Data bits
7, 8
Stop bits
1, 2
Flow control
None, Xon-Xoff, RTS-CTS
None
Parity
None, odd, even
None
3.2 Host interface behaviour

The host interface behaviour can be influenced by the following configuration setup (user
interface):
Item
Specification
Default
Host
ON, OFF
OFF
Protocol
ASTM plus, ASTM Urisys 2400
ASTM plus
Raw data to host
OFF, ON, upload only (setup in service)
OFF
Checksum
On, Off
On
The automatic result transmission is active when the host support is switched to ON.
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3.3 Serial cable

The cobas u 411 uses a serial asynchronous interface cable (RS 232) connected to the host
computer. The port COM 2 of the host system is usually allocated to this communication, but can
vary depending on the host system.
According to the serial asynchronous specification, the maximum cable length is 15 m. It is
recommended by Roche to use a 3 meter cable. All other cable length apart from the
recommended must be organized locally.
The following cable is assigned to use for connecting the cobas u 411 to the host system:
Host Interface Cable RS 232, IBM PC Null modem D-Sub 9 pins, 3m
Please see table below for wiring details:
cobas u 411
Plug 9 pin female
Relevance
Host System
Plug 9 pin female
1
2
3
4
5
6
7
8
9
RXD
TXD
DTR
GND
DSR
RTS
CTS
3
2
6
5
4
8
7
-
Legend:
RxD = Receiving data
TxD = Transmitting data
DTR = Data terminal ready
GND = Ground
DSR = Data set ready
RTS = Request to send
CTS = Clear to send
Note: If flow control is set to None or Xon-Xoff then the pin 4/6 and pin 7/8 (handshake
connections) are not required.
4 Error handling (behaviour of a failed transmission)

There are two different types of error handling:
Host system does not acknowledge the transmission:
An alarm message (red alarm LED is activated) will occur if the transmission of data is not
confirmed by the host system. The failed transmission will not be repeated.
Host receives wrong data:

In case the host system has received wrong data (e.g. wrong checksum), the incorrect
sequence will be repeated. After three failed attempts, the transmission will be aborted and
an alarm message will be displayed (red alarm LED is activated).
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5 Description of the supported protocols

5.1 ASTM plus protocol
5.1.1 General
This chapter describes the ASTM plus protocol. The ASTM plus protocol consists of Records,
Frames and Messages.
A record is the smallest logical group of information
A frame is a defined data structure that contains a data block to be transmitted
Messages are a collection of several records packed in frames into a logical unit
Note: The ASTM plus protocol is based on the ASTM protocol specification.
Records
A record is the smallest logical group of information. The ASTM plus protocol supports the
following records:
Identification
H
P
Name
Header record
Patient information
record
O
R
C
Order record
Result record
Comment record
Manufacturer record
Request information
record (query)
Termination record
Description
First record in every message, mandatory
This record is used to download patient demographics
from the host system to the analyzer. With the cobas u
411 no patient data can be handled. Therefore the
patient record is always empty.
This record defines the attributes of a particular order
Measurement data
This record is used for the transmission of sample flags
and result flags.
This record is used for the transmission of raw data,
additional information for patient and control results
Worklist request (query)
Last record in every message, mandatory
Frames
A frame is a defined data structure that encapsulates a data block to be transmitted. According to
the ASTM plus protocol specification, a frame may contain one or more records. However, the
implementation in the cobas u 411 analyzer contains one record only. Each frame has the
following structure:
Description
ASCII
(hex)
Start of
text
STX
(0x02)
Frame
No.
Protocol
specific
record
data
End of
text
ETX
(0x03)
Checksum
Carriage
return
CR
(0x0D)
Line feed
LF
(0x0A)
The frame no. always starts at 1 and will be incremented by one for each record. If the frame
reaches no. 7, the numbering starts at 0 (zero).
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Messages
Messages are collections of several records packed in frames into a logical unit. A message starts
with the Header Record (H) and finishes with the Termination Record (L).
5.1.2 Communication startup

Only the cobas u 411 analyzer can start a communication. The cobas u 411 analyzer is always
the master, the host system the slave.
Exception: After the successful handling of the worklist request sequence, the master function
temporarily belongs to the host system for the duration of the worklist transmission.
A communication is initialized when the ASCII character ENQ
(Hex 05) is sent to the host system.
The host system (slave) acknowledges its readiness to
communicate by sending the ASCII character ACK (Hex 06) or
if it is not ready the ASCII character NAK (Hex 15).
cobas u 411
If the host system has positively acknowledged its readiness to

communicate (ACK), the cobas u 411 analyzer transmits the
message frame by frame.
The host system confirms the frame reception with ACK.
The host system can trigger a resending of the last sent frame
with NAK.
The communication session is terminated with the ASCII
character EOT (Hex 04).
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5.1.3 Record description

In this chapter, the meaning of the fields in individual records will be explained in the form of tables.
Fields which are not supported by the cobas u 411 analyzer are highlighted in grey. For a better
comprehension, there is a detailed example for each record description following the table.
Example trace files of different data interchanges are added at the end of this protocol description.
Message header record

Every message starts with a Message Header Record. This record is mandatory.
No. Field
1
Record type ID
Content
H
|
\
^
&
3
4
5
6
7
8
9
10
11
12
13
14
Field delimiter
Repeat delimiter
Component delimiter
Escape delimiter
Message control ID
Access password
Sender name or ID
Sender street address

Reserved field
Sender telephone
number
Characteristics of
sender
Receiver ID
Comment of special
instructions
Processing ID
Version no.
Date and time of
message
cobas u 411
^serial no.
^software version
^range boundary
setting
Comment
The character H identifies the record as a
message header record.
Defines the delimiters to be used throughout
the subsequent records of the message.
Not used in cobas u 411 analyzer

First sub field contains cobas u 411, second
sub field contains serial number (10 digits,
e.g. 0000000001), third sub field contains the
software version, and the fourth sub field
contains the range boundary setting
Always P (production)
Date and time (format YYYYMMDDhhmmss)
example 20110315101822)
Example:
No:
Frame
1 2
3 4
5
6 7 8 9 10
Content: [STX] 1 H | \^& | | | cobasu411^8^3.2.0.1001Înt | | | | | |
No:
11 12 13 14
CR
Frame
Content: | | P | | 20110315101822 [CR] [ETX]71[CR][LF]
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Patient information record

Although the cobas u 411 analyzer does not save any patient data, the Patient Information
Record is mandatory by the ASTM plus standard. Therefore, the cobas u 411 analyzer simply
transmits an empty record.
No.
1
2
3 .. 35
Field
Record type ID
Content
P
Comment
The character P identifies the record as a
patient record.
Sequence no.
1
The cobas u 411 analyzer sends one order
per transmission only. Therefore this value is
always 1.
All further fields are not supported and not transmitted
Example:
No:
Frame
1
2 CR
Frame
Content: [STX] 2 P | 1 [CR] [ETX]3F[CR][LF]
Order record
In the Order Record general sample information such as sample ID, sequence number, etc. will
be transmitted.
No.
1
Field
Record type ID
Content
O
Sequence no.
Specimen ID
sample ID
Instrument
specimen ID
sample no.
^rack ID
^position no.
ôperator ID
^data carrier type
5
6
Universal test ID
Priority
Request / ordered
date and time
Specimen
collection date and
time
Collection end time
Collection volume
Collector ID
Action code
X or X\Q
Always X, in case of control samples X\Q
Danger code
Relevant clinical
information
Date / time
specimen received
example 20110315101822
9
10
11
12
13
14
15
16 .. 31
Comment
The character O identifies the record as an
order record.
always 1.
ID of the sample, numerical or
alphanumerical value (e.g. 001)
The cobas u 411 analyzer supports only
sample no. and data carrier type (SAMPLE
for patient samples, CONTROL for control
samples).For order download, the sample no.
is not needed and is ignored.
Always R (routine sample)
The cobas u 411 analyzer does not support
emergency samples
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Example patient sample:

No:
Frame
1
2
3
4
5
6 7 8 9 10 11 12 13 14
Content: [STX] 3 O | 1 | 001 | 1^^^^SAMPLE | | R | | | | | | X | | |
No:
15
CR
Frame
Content: 20110315101754 [CR] [ETX]F0[CR][LF]
Example control sample:

No:
Frame
1
2 3
4
5
6 7 8 9 10 11 12 13 14
Content: [STX] 3 O | 1 | | 0^^^^CONTROL | | R | | | | | | X\Q | | |
No:
15
CR
Frame
Content: 20110315100924 [CR] [ETX]68[CR][LF]
Result record
The cobas u 411 analyzer uses the Result Record to transmit the measurement data. Each test
needs a separate Result Record. Flags are sent in the Comment Record and must be observed.
No.
1
Field
Record type ID
Content
R
Sequence no.
1 1000
Universal test ID
Data or
measurement value
test no.
^test code
result value
ârbitrary value
Unit
unit
Reference ranges
Result abnormal flag
Nature of
abnormality testing
Result status
Date of change in
instrument
normative values or
units
Operator ID
user ID
User ID of operator who performed the test
9
10
11
12 .. 14
Comment
The character R identifies the record as a
result record.
The cobas u 411 stores up to 1000 results
(color, clarity and sediment parameters
included)
Test no. list (e.g. 1) see 6.2
Test code (e.g. SG) see 6.2
Result value: numerical value (e.g. 1.030) or
alphanumerical value (e.g. neg.)
Arbitrary value: additional, this subfield is
only used if arbitrary values are used in
combination with others (Conventional or SI);
arbitrary values for color and clarity dont
exist
Alphanumerical value (e.g. mg/dl), only if
result can be represented by several units
Not used in cobas u 411 analyzer, not
equivalent to range tables used in cobas u
411 analyzer
Not used in cobas u 411 analyzer,
abnormal flags are sent in the comment
record
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Example:
No:
Frame
1
2
3
4
5 6 7 8 9 10 11
CR
Frame
Content: [STX] 4 R | 1 | 1^SG | 1.005 | | | | | | | service [CR] [ETX]AD
No:
Frame
Content: [CR][LF]
Comment record
The cobas u 411 analyzer uses the Comment Record to transmit the sample flags and result
flags. When at least one flag is present, this record will be attached to all corresponding Result
Records of the sample.
No. Field
1
Record type ID
Content
C
Sequence no.
1 1000
3
4
Comment source
Comment text
I
Sample Flags /
Sample Result Flags
Comment type
Attention:
Comment
The character C identifies the record as a
comment record.
The cobas u 411 analyzer uses the same
sequence number as the prior result record.
Always I (clinical instrument system)
The cobas u 411 analyzer uses the
comment record only for transmitting flags,
each flag is separated with the ^ delimiter.
Always I (instrument flag(s) comment)
decisions!
Read the chapter 2.4 Flags for detailed information!
Example (result record with additional comment record
edited result: !-Flag):

Result Record
Content: [STX]5R|2|2^pH|6|||||||service[CR][ETX]10[CR][LF]
No:
Frame
1
2
3
4
5 CR
Frame
Content: [STX] 6 C | 2 | I | ! | I [CR] [ETX]5E[CR][LF]
Comment Record
abnormal and sieve: *-Flag and S-Flag):

Result Record
Content: [STX]5R|2|2^pH|8|||||||service[CR][ETX]12[CR][LF]
No:
Frame
1
2
3
4
5 CR
Frame
Content: [STX] 6 C | 2 | I | *^S | I [CR] [ETX]18[CR][LF]
Comment Record
test strip error: T-Flag):

Result Record
Content: [STX]4R|1|1^SG||||||||service[CR][ETX]B9[CR][LF]
No:
Frame
1
2
3
4
5 CR
Frame
Content: [STX] 5 C | 1 | I | T | I [CR] [ETX]8F[CR][LF]
Comment Record
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Manufacturer record (raw result record - RR)

The cobas u 411 analyzer uses the Manufacturer Record RR to transmit raw data for special
application (e.g. evaluation / research). It is possible to activate this application via the user
interface (Utilities / Tools2 / Service Raw Data to Host
ON)
No. Field
1
Record type ID
Content
M
2
3
4
Sequence no.
Record type sub-ID
Universal test ID
Test frequency
1 1000
RR
test no.^
test code
frequency
Raw result value
reflectance
Comment
The character M identifies the record as a
manufacturer record.
Running number
Always RR (raw result)
Test no. list (e.g. 1) see 6.2
Test code (e.g. SG) see 6.2
LED frequency (e.g. green)
blue (~470 nm)
green (~555 nm)
orange (~620 nm)
Floating number in the format ##.## (e.g.
88.06)
Example:
No:
Frame
1
2
3
4
5
6
CR
Frame
Content: [STX] 0 M | 1 | RR | 11^COM | blue | 78.19 [CR] [ETX]1C[CR][LF]
Manufacturer record (result context record - RC)

The cobas u 411 analyzer uses the Result Context Record for the transmission of additional
information for patients or controls.
No.
1
2
3
4
Field
Record type ID
Sequence no.
Record type sub-ID
Calibration strip lot
number
Calibration strip
expiration date
Test strip expiration
date
Control name
Control lot number
e.g. 7890
10
Control expiration date
e.g. 20061231
5
6
7
Content
M
1
RC
e.g. 4567
Comment
Needed by ASTM, always M
Running number
Always RC (result context)
Numerical or alphanumerical value
e.g. 20061231
Date and time format (YYYYMMDD)
e.g. 1234
e.g. 20061231
Numerical or alphanumerical value

e.g. ctrl
Patient sample: always empty

Control sample: control name
Control sample: control lot no
Control sample: control expiration date

No:
Frame
1
2
3
4 5
6
7
8 9 10 CR
Content: [STX] 0 M | 1 | RC | | | 2001601 | 20111001 | | |
[CR]
No:
Frame
Content: [ETX]8F[CR][LF]
V 2.1
18 / 52
cobas u 411
Host

No:
Frame
1
2
3
4 5
6
7
8
9
Content: [STX] 7 M | 1 | RC | | | 2001601 | 20111001 | ctrl | 123456 |
No:
10
CR
Frame
Content: 20111001 [CR] [ETX]06[CR][LF]
Request information record (request for worklist download)

The cobas u 411 analyzer uses the Request Information Record to request the work list from the
host system. The host system must answer within 3 seconds.
No.
1
Field
Record type ID
2
3
4 .. 13
Content
Q
Comment
The character Q identifies the record as a
request information record.
Sequence no.
1
Always 1, using the cobas u 411 analyzer
Record type sub-ID ÂLL
Request for all orders
Example:
No:
Frame
1
2
3
CR
Frame
Content: [STX] 2 Q | 1 | ÂLL [CR] [ETX]F3[CR][LF]
Termination record
Each message is closed with the Message Terminator Record. This record is mandatory.
No.
1
2
3
Field
Record type ID
Sequence no.
Termination code
Content
L
1
N
Comment
Needed by ASTM, always L
Always 1
N for normal end of message
Example:
No:
Frame
1
2
3 CR
Frame
Content: [STX] 1 L | 1 | N [CR] [ETX]04[CR][LF]
Scientific record
This type of record is not used in cobas u 411 analyzer (the character S would identify the record
as a scientific record).
V 2.1
19 / 52
cobas u 411
Host
5.1.4 ASTM plus trace file examples

Example: Upload sample result without raw data
- Sample 1
- Sample 2 (with !-flag for pH)
- Sample 3 (with *- and S-Flag for pH and sediment data for ERY and LEU)
- Sample 4 (with T-flag)
Example: Upload sample result with raw data
- Sample 1
- Sample 3 (with *- and S-Flag for pH and sediment data for ERY and LEU)
Example: Upload control result without raw data
Example: Upload control result with raw data
Example: Worklist download

Sample 1
u411
Host
u411
Host
u411
Host
u411
Host
u411
Host
u411
Host
u411
Host
u411
Host
u411
Host
u411
Host
u411
Host
u411
Host
u411
Host
u411
10:17:03,686 [ENQ]
10:17:03,686 [ACK]
10:17:03,795 [STX]1H|\^&|||cobasu411^8^3.2.0.1001Înt|||||
||P||20110315101822[CR][ETX]71[CR][LF]
10:17:03,811 [ACK]
10:17:03,842 [STX]2P|1[CR][ETX]3F[CR][LF]
10:17:03,858 [ACK]
10:17:03,936 [STX]3O|1|001|1^^^^SAMPLE||R||||||X|||201103151
01754[CR][ETX]F0[CR][LF]
10:17:03,951 [ACK]
10:17:04,029 [STX]4R|1|1^SG|1.005|||||||service[CR][ETX]AD[C
R][LF]
10:17:04,029 [ACK]
10:17:04,108 [STX]5R|2|2^pH|7|||||||service[CR][ETX]11[CR][L
F]
10:17:04,108 [ACK]
10:17:04,186 [STX]6R|3|3^LEU|neg|||||||service[CR][ETX]45[CR
][LF]
10:17:04,186 [ACK]
10:17:04,264 [STX]7R|4|4^NIT|neg|||||||service[CR][ETX]4D[CR
][LF]
10:17:04,264 [ACK]
10:17:04,342 [STX]0R|5|5^PRO|neg|||||||service[CR][ETX]4E[CR
][LF]
10:17:04,342 [ACK]
10:17:04,420 [STX]1R|6|6^GLU|neg|||||||service[CR][ETX]48[CR
][LF]
10:17:04,420 [ACK]
10:17:04,498 [STX]2R|7|7^KET|neg|||||||service[CR][ETX]47[CR
][LF]
10:17:04,498 [ACK]
10:17:04,576 [STX]3R|8|8ÛBG|neg|||||||service[CR][ETX]44[CR
][LF]
10:17:04,592 [ACK]
10:17:04,654 [STX]4R|9|9^BIL|neg|||||||service[CR][ETX]40[CR
][LF]
10:17:04,670 [ACK]
10:17:04,764 [STX]5R|10|10ÊRY|neg|||||||service[CR][ETX]AA[
V 2.1
20 / 52
cobas u 411
Host
u411
Host
u411
Host
u411
Host
u411
Host
u411
Host
CR][LF]
10:17:04,764 [ACK]
10:17:04,842 [STX]6R|11|11^COL|p.yel|||||||service[CR][ETX]4
9[CR][LF]
10:17:04,842 [ACK]
10:17:04,920 [STX]7R|12|12^CLA||||||||service[CR][ETX]56[CR]
[LF]
10:17:04,920 [ACK]
10:17:04,998 [STX]0M|1|RC|||2001601|20111001|||[CR][ETX]8F[C
R][LF]
10:17:04,998 [ACK]
10:17:05,061 [STX]1L|1|N[CR][ETX]04[CR][LF]
10:17:05,061 [ACK]
10:17:05,108 [EOT]
Sample 2 (with !-flag for pH)

u411
Host
u411
Host
u411
Host
u411
Host
u411
Host
u411
Host
u411
Host
u411
Host
u411
Host
u411
Host
u411
Host
u411
Host
u411
Host
u411
Host
u411
Host
u411
11:01:02,941 [ENQ]
11:01:02,941 [ACK]
11:01:03,051 [STX]1H|\^&|||cobasu411^8^3.2.0.1001Înt|||||
||P||20110315110221[CR][ETX]6A[CR][LF]
11:01:03,051 [ACK]
11:01:03,098 [STX]2P|1[CR][ETX]3F[CR][LF]
11:01:03,098 [ACK]
11:01:03,191 [STX]3O|1|002|2^^^^SAMPLE||R||||||X|||201103151
02140[CR][ETX]E8[CR][LF]
11:01:03,191 [ACK]
11:01:03,270 [STX]4R|1|1^SG|1.010|||||||service[CR][ETX]A9[C
R][LF]
11:01:03,285 [ACK]
F]
11:01:03,363 [ACK]
11:01:03,426 [STX]6C|2|I|!|I[CR][ETX]5E[CR][LF]
11:01:03,426 [ACK]
][LF]
11:01:03,504 [ACK]
11:01:03,582 [STX]0R|4|4^NIT|neg|||||||service[CR][ETX]46[CR
][LF]
11:01:03,582 [ACK]
11:01:03,660 [STX]1R|5|5^PRO|neg|||||||service[CR][ETX]4F[CR
][LF]
11:01:03,660 [ACK]
][LF]
11:01:03,738 [ACK]
][LF]
11:01:03,817 [ACK]
][LF]
11:01:03,895 [ACK]
][LF]
11:01:03,988 [ACK]
11:01:04,051 [STX]6R|10|10ÊRY|neg|||||||service[CR][ETX]AB[
CR][LF]
11:01:04,067 [ACK]
A[CR][LF]
V 2.1
21 / 52
cobas u 411
Host
u411
Host
u411
Host
u411
Host
u411
Host
11:01:04,145 [ACK]
11:01:04,223 [STX]0R|12|12^CLA||||||||service[CR][ETX]4F[CR]
[LF]
11:01:04,223 [ACK]
11:01:04,301 [STX]1M|1|RC|||2001601|20111001|||[CR][ETX]90[C
R][LF]
11:01:04,301 [ACK]
11:01:04,363 [STX]2L|1|N[CR][ETX]05[CR][LF]
11:01:04,363 [ACK]
11:01:04,395 [EOT]
Sample 3 (with *- and S-flag for pH and sediment data for ERY and LEU)
u411
Host
u411
Host
u411
Host
u411
Host
u411
Host
u411
Host
u411
Host
u411
Host
u411
Host
u411
Host
u411
Host
u411
Host
u411
Host
u411
Host
u411
Host
u411
Host
u411
Host
10:29:19,382 [ENQ]
10:29:19,382 [ACK]
10:29:19,492 [STX]1H|\^&|||cobasu411^8^3.2.0.1001Înt|||||
||P||20110315103037[CR][ETX]71[CR][LF]
10:29:19,492 [ACK]
10:29:19,539 [STX]2P|1[CR][ETX]3F[CR][LF]
10:29:19,539 [ACK]
10:29:19,632 [STX]3O|1|003|3^^^^SAMPLE||R||||||X|||201103151
02801[CR][ETX]EE[CR][LF]
10:29:19,632 [ACK]
R][LF]
10:29:19,710 [ACK]
F]
10:29:19,789 [ACK]
10:29:19,851 [STX]6C|2|I|*^S|I[CR][ETX]18[CR][LF]
10:29:19,851 [ACK]
][LF]
10:29:19,960 [ACK]
][LF]
10:29:20,039 [ACK]
][LF]
10:29:20,117 [ACK]
][LF]
10:29:20,195 [ACK]
][LF]
10:29:20,273 [ACK]
][LF]
10:29:20,351 [ACK]
][LF]
10:29:20,429 [ACK]
CR][LF]
10:29:20,523 [ACK]
A[CR][LF]
10:29:20,617 [ACK]
[LF]
10:29:20,695 [ACK]
V 2.1
22 / 52
cobas u 411
u411
Host
u411
Host
u411
Host
u411
Host
u411
Host
10:29:20,773 [STX]1R|13|51ÊRY|5-10|||||||service[CR][ETX]37
[CR][LF]
10:29:20,773 [ACK]
10:29:20,867 [STX]2R|14|52^LEU|11-20|||||||service[CR][ETX]
7E[CR][LF]
10:29:20,867 [ACK]
10:29:20,945 [STX]3M|1|RC|||2001601|20111001|||[CR][ETX]92[C
R][LF]
10:29:20,945 [ACK]
10:29:21,007 [STX]4L|1|N[CR][ETX]07[CR][LF]
10:29:21,007 [ACK]
10:29:21,054 [EOT]
Sample 4 (with T-flag)

u411
Host
u411
Host
u411
Host
u411
Host
u411
Host
u411
Host
u411
Host
u411
Host
u411
Host
u411
Host
u411
Host
u411
Host
u411
Host
u411
Host
u411
Host
u411
Host
u411
Host
u411
Host
u411
10:31:58,340 [ENQ]
10:31:58,340 [ACK]
10:31:58,450 [STX]1H|\^&|||cobasu411^8^3.2.0.1001Înt|||||
||P||20110315103316[CR][ETX]71[CR][LF]
10:31:58,465 [ACK]
10:31:58,528 [STX]2P|1[CR][ETX]3F[CR][LF]
10:31:58,528 [ACK]
10:31:58,621 [STX]3O|1|004|4^^^^SAMPLE||R||||||X|||201103151
10:31:58,621 [ACK]
10:31:58,700 [STX]4R|1|1^SG||||||||service[CR][ETX]B9[CR][LF
]
10:31:58,700 [ACK]
10:31:58,762 [STX]5C|1|I|T|I[CR][ETX]8F[CR][LF]
10:31:58,762 [ACK]
10:31:58,840 [STX]6R|2|2^pH||||||||service[CR][ETX]DB[CR][LF
]
10:31:58,840 [ACK]
10:31:58,903 [STX]7C|2|I|T|I[CR][ETX]92[CR][LF]
10:31:58,903 [ACK]
10:31:58,981 [STX]0R|3|3^LEU||||||||service[CR][ETX]05[CR][L
F]
10:31:58,981 [ACK]
10:31:59,043 [STX]1C|3|I|T|I[CR][ETX]8D[CR][LF]
10:31:59,059 [ACK]
10:31:59,121 [STX]2R|4|4^NIT||||||||service[CR][ETX]0E[CR][L
F]
10:31:59,137 [ACK]
10:31:59,200 [ACK]
10:31:59,278 [STX]4R|5|5^PRO||||||||service[CR][ETX]18[CR][L
F]
10:31:59,278 [ACK]
10:31:59,340 [ACK]
10:31:59,418 [STX]6R|6|6^GLU||||||||service[CR][ETX]13[CR][L
F]
10:31:59,418 [ACK]
10:31:59,481 [ACK]
10:31:59,559 [STX]0R|7|7^KET||||||||service[CR][ETX]0B[CR][L
F]
10:31:59,559 [ACK]
10:31:59,621 [ACK]
10:31:59,700 [STX]2R|8|8ÛBG||||||||service[CR][ETX]09[CR][L
V 2.1
23 / 52
cobas u 411
Host
u411
Host
u411
10:31:59,715
10:31:59,762
10:31:59,778
10:31:59,840
Host
u411
Host
u411
10:31:59,856
10:31:59,918
10:31:59,918
10:31:59,996
Host
u411
Host
u411
10:31:59,996
10:32:00,059
10:32:00,059
10:32:00,137
Host
u411
Host
u411
10:32:00,137
10:32:00,200
10:32:00,200
10:32:00,278
Host
u411
10:32:00,278
10:32:00,356
Host
u411
Host
u411
10:32:00,371
10:32:00,418
10:32:00,434
10:32:00,465
Host
F]
[ACK]
[STX]3C|8|I|T|I[CR][ETX]94[CR][LF]
[ACK]
[STX]4R|9|9^BIL||||||||service[CR][ETX]06[CR][L
F]
[ACK]
[STX]5C|9|I|T|I[CR][ETX]97[CR][LF]
[ACK]
[STX]6R|10|10ÊRY||||||||service[CR][ETX]71[CR]
[LF]
[ACK]
[STX]7C|10|I|T|I[CR][ETX]C1[CR][LF]
[ACK]
[STX]0R|11|11^COL||||||||service[CR][ETX]5B[CR]
[LF]
[ACK]
[STX]1C|11|I|T|I[CR][ETX]BC[CR][LF]
[ACK]
[STX]2R|12|12^CLA||||||||service[CR][ETX]51[CR]
[LF]
[ACK]
[STX]3M|1|RC|||2001601|20111001|||[CR][ETX]92[C
R][LF]
[ACK]
[STX]4L|1|N[CR][ETX]07[CR][LF]
[ACK]
[EOT]

Sample 1
u411
Host
u411
Host
u411
Host
u411
Host
u411
Host
u411
Host
u411
Host
u411
Host
u411
Host
u411
Host
10:36:26,562 [ENQ]
10:36:26,562 [ACK]
10:36:26,672 [STX]1H|\^&|||cobasu411^8^3.2.0.1001Înt|||||
||P||20110315103745[CR][ETX]77[CR][LF]
10:36:26,672 [ACK]
10:36:26,734 [STX]2P|1[CR][ETX]3F[CR][LF]
10:36:26,734 [ACK]
10:36:26,828 [STX]3O|1|001|1^^^^SAMPLE||R||||||X|||201103151
10:36:26,828 [ACK]
10:36:26,906 [STX]4R|1|1^SG|1.005|||||||service[CR][ETX]AD[C
R][LF]
10:36:26,906 [ACK]
F]
10:36:27,000 [ACK]
][LF]
10:36:27,078 [ACK]
][LF]
10:36:27,156 [ACK]
][LF]
10:36:27,234 [ACK]
][LF]
10:36:27,312 [ACK]
V 2.1
24 / 52
cobas u 411
u411
Host
u411
Host
u411
Host
u411
Host
u411
Host
u411
Host
u411
Host
u411
Host
u411
Host
u411
Host
u411
Host
u411
Host
u411
Host
u411
Host
u411
Host
u411
Host
u411
Host
u411
Host
u411
Host
u411
Host
u411
Host
][LF]
10:36:27,390 [ACK]
][LF]
10:36:27,468 [ACK]
][LF]
10:36:27,547 [ACK]
CR][LF]
10:36:27,625 [ACK]
9[CR][LF]
10:36:27,718 [ACK]
[LF]
10:36:27,797 [ACK]
10:36:27,875 [STX]0M|1|RR|11^COM|blue|78.19[CR][ETX]1C[CR][L
F]
10:36:27,875 [ACK]
10:36:27,953 [STX]1M|2|RR|11^COM|green|76.80[CR][ETX]83[CR][
LF]
10:36:27,953 [ACK]
10:36:28,031 [STX]2M|3|RR|11^COM|orange|76.23[CR][ETX]ED[CR]
[LF]
10:36:28,031 [ACK]
10:36:28,109 [STX]3M|4|RR|10ÊRY|green|69.07[CR][ETX]98[CR][
LF]
10:36:28,109 [ACK]
10:36:28,187 [STX]4M|5|RR|10ÊRY|orange|73.75[CR][ETX]05[CR]
[LF]
10:36:28,187 [ACK]
10:36:28,265 [STX]5M|6|RR|3^LEU|green|77.50[CR][ETX]61[CR][L
F]
10:36:28,265 [ACK]
10:36:28,343 [STX]6M|7|RR|4^NIT|green|77.37[CR][ETX]6E[CR][L
F]
10:36:28,359 [ACK]
10:36:28,422 [STX]7M|8|RR|7^KET|green|61.63[CR][ETX]64[CR][L
F]
10:36:28,437 [ACK]
10:36:28,515 [STX]0M|9|RR|6^GLU|green|78.90[CR][ETX]69[CR][L
F]
10:36:28,515 [ACK]
10:36:28,593 [STX]1M|10|RR|5^PRO|orange|70.13[CR][ETX]F8[CR]
[LF]
10:36:28,593 [ACK]
10:36:28,672 [STX]2M|11|RR|8ÛBG|green|75.19[CR][ETX]8A[CR][
LF]
10:36:28,672 [ACK]
10:36:28,750 [STX]3M|12|RR|9^BIL|green|74.79[CR][ETX]8B[CR][
LF]
10:36:28,750 [ACK]
10:36:28,828 [STX]4M|13|RR|2^pH|green|36.18[CR][ETX]5E[CR][L
F]
10:36:28,828 [ACK]
10:36:28,906 [STX]5M|14|RR|2^pH|orange|25.07[CR][ETX]C7[CR][
LF]
10:36:28,906 [ACK]
10:36:28,984 [STX]6M|15|RR|1^SG|orange|06.51[CR][ETX]A8[CR][
LF]
V 2.1
25 / 52
cobas u 411
Host
u411
Host
u411
Host
u411
Host
10:36:29,000 [ACK]
10:36:29,062 [STX]7M|16|RC|||2001601|20111001|||[CR][ETX]CC[
CR][LF]
10:36:29,078 [ACK]
10:36:29,125 [STX]0L|1|N[CR][ETX]03[CR][LF]
10:36:29,140 [ACK]
10:36:29,187 [EOT]

u411
Host
u411
Host
u411
Host
u411
Host
u411
Host
u411
Host
u411
Host
u411
Host
u411
Host
u411
Host
u411
Host
u411
Host
u411
Host
u411
Host
u411
Host
u411
Host
u411
Host
u411
Host
10:59:53,165 [ENQ]
10:59:53,165 [ACK]
10:59:53,274 [STX]1H|\^&|||cobasu411^8^3.2.0.1001Înt|||||
||P||20110315110111[CR][ETX]68[CR][LF]
10:59:53,274 [ACK]
10:59:53,321 [STX]2P|1[CR][ETX]3F[CR][LF]
10:59:53,321 [ACK]
10:59:53,415 [STX]3O|1|002|2^^^^SAMPLE||R||||||X|||201103151
02140[CR][ETX]E8[CR][LF]
10:59:53,431 [ACK]
R][LF]
10:59:53,509 [ACK]
F]
10:59:53,587 [ACK]
10:59:53,649 [STX]6C|2|I|!|I[CR][ETX]5E[CR][LF]
10:59:53,649 [ACK]
][LF]
10:59:53,728 [ACK]
][LF]
10:59:53,806 [ACK]
][LF]
10:59:53,884 [ACK]
][LF]
10:59:53,962 [ACK]
][LF]
10:59:54,040 [ACK]
][LF]
10:59:54,134 [ACK]
][LF]
10:59:54,212 [ACK]
CR][LF]
10:59:54,290 [ACK]
A[CR][LF]
10:59:54,368 [ACK]
[LF]
10:59:54,446 [ACK]
10:59:54,525 [STX]1M|1|RR|11^COM|blue|77.14[CR][ETX]17[CR][L
F]
10:59:54,525 [ACK]
V 2.1
26 / 52
cobas u 411
u411
Host
u411
Host
u411
Host
u411
Host
u411
Host
u411
Host
u411
Host
u411
Host
u411
Host
u411
Host
u411
Host
u411
Host
u411
Host
u411
Host
u411
Host
u411
Host
u411
Host
LF]
10:59:54,603 [ACK]
10:59:54,681 [STX]3M|3|RR|11^COM|orange|74.93[CR][ETX]F3[CR]
[LF]
10:59:54,681 [ACK]
10:59:54,759 [STX]4M|4|RR|10ÊRY|green|66.56[CR][ETX]9A[CR][
LF]
10:59:54,775 [ACK]
[LF]
10:59:54,853 [ACK]
F]
10:59:54,931 [ACK]
10:59:55,009 [STX]7M|7|RR|4^NIT|green|78.86[CR][ETX]74[CR][L
F]
10:59:55,009 [ACK]
F]
10:59:55,087 [ACK]
10:59:55,165 [STX]1M|9|RR|6^GLU|green|78.04[CR][ETX]65[CR][L
F]
10:59:55,165 [ACK]
[LF]
10:59:55,243 [ACK]
10:59:55,322 [STX]3M|11|RR|8ÛBG|green|75.26[CR][ETX]89[CR][
LF]
10:59:55,322 [ACK]
10:59:55,400 [STX]4M|12|RR|9^BIL|green|74.40[CR][ETX]80[CR][
LF]
10:59:55,415 [ACK]
10:59:55,478 [STX]5M|13|RR|2^pH|green|35.32[CR][ETX]5A[CR][L
F]
10:59:55,494 [ACK]
LF]
10:59:55,572 [ACK]
10:59:55,650 [STX]7M|15|RR|1^SG|orange|05.68[CR][ETX]B0[CR][
LF]
10:59:55,650 [ACK]
10:59:55,728 [STX]0M|16|RC|||2001601|20111001|||[CR][ETX]C5[
CR][LF]
10:59:55,728 [ACK]
10:59:55,790 [STX]1L|1|N[CR][ETX]04[CR][LF]
10:59:55,790 [ACK]
10:59:55,837 [EOT]
Sample 3 (with *- and S-flag for pH and sediment data for ERY and LEU)
u411
Host
u411
Host
u411
Host
u411
Host
10:37:48,828 [ENQ]
10:37:48,843 [ACK]
10:37:48,937 [STX]1H|\^&|||cobasu411^8^3.2.0.1001Înt|||||
||P||20110315103907[CR][ETX]77[CR][LF]
10:37:48,953 [ACK]
10:37:48,984 [STX]2P|1[CR][ETX]3F[CR][LF]
10:37:49,000 [ACK]
10:37:49,093 [STX]3O|1|003|3^^^^SAMPLE||R||||||X|||201103151
02801[CR][ETX]EE[CR][LF]
10:37:49,093 [ACK]
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Host
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Host
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Host
u411
Host
u411
Host
u411
Host
Host
R][LF]
10:37:49,172 [ACK]
F]
10:37:49,250 [ACK]
10:37:49,312 [STX]6C|2|I|*^S|I[CR][ETX]18[CR][LF]
10:37:49,312 [ACK]
][LF]
10:37:49,390 [ACK]
][LF]
10:37:49,468 [ACK]
][LF]
10:37:49,547 [ACK]
][LF]
10:37:49,640 [ACK]
][LF]
10:37:49,718 [ACK]
][LF]
10:37:49,797 [ACK]
][LF]
10:37:49,875 [ACK]
CR][LF]
10:37:49,953 [ACK]
A[CR][LF]
10:37:50,031 [ACK]
[LF]
10:37:50,109 [ACK]
10:37:50,187 [STX]1R|13|51ÊRY|5-10|||||||service[CR][ETX]37
[CR][LF]
10:37:50,187 [ACK]
10:37:50,265 [STX]2R|14|52^LEU|11-20|||||||service[CR][ETX]
7E[CR][LF]
10:37:50,281 [ACK]
10:37:50,343 [STX]3M|1|RR|11^COM|blue|74.73[CR][ETX]1B[CR][L
F]
10:37:50,359 [ACK]
LF]
10:37:50,437 [ACK]
10:37:50,515 [STX]5M|3|RR|11^COM|orange|73.35[CR][ETX]F0[CR]
[LF]
10:37:50,515 [ACK]
10:37:50,593 [STX]6M|4|RR|10ÊRY|green|68.63[CR][ETX]9C[CR][
LF]
10:37:50,593 [ACK]
[LF]
10:37:50,672 [ACK]
10:37:50,750 [STX]0M|6|RR|3^LEU|green|76.22[CR][ETX]5A[CR][L
F]
10:37:50,750 [ACK]
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u411
Host
u411
Host
10:37:50,828 [STX]1M|7|RR|4^NIT|green|77.83[CR][ETX]6A[CR][L
F]
10:37:50,828 [ACK]
10:37:50,906 [STX]2M|8|RR|7^KET|green|62.44[CR][ETX]5F[CR][L
F]
10:37:50,906 [ACK]
10:37:50,984 [STX]3M|9|RR|6^GLU|green|79.26[CR][ETX]6C[CR][L
F]
10:37:51,000 [ACK]
10:37:51,062 [STX]4M|10|RR|5^PRO|orange|70.25[CR][ETX]FE[CR]
[LF]
10:37:51,078 [ACK]
LF]
10:37:51,156 [ACK]
LF]
10:37:51,234 [ACK]
10:37:51,312 [STX]7M|13|RR|2^pH|green|35.36[CR][ETX]60[CR][L
F]
10:37:51,312 [ACK]
10:37:51,390 [STX]0M|14|RR|2^pH|orange|24.20[CR][ETX]BC[CR][
LF]
10:37:51,390 [ACK]
LF]
10:37:51,468 [ACK]
10:37:51,547 [STX]2M|16|RC|||2001601|20111001|||[CR][ETX]C7[
CR][LF]
10:37:51,547 [ACK]
10:37:51,609 [STX]3L|1|N[CR][ETX]06[CR][LF]
10:37:51,625 [ACK]
10:37:51,656 [EOT]

u411
Host
u411
Host
u411
Host
u411
Host
u411
Host
u411
Host
u411
Host
u411
Host
u411
Host
u411
Host
10:38:09,531 [ENQ]
10:38:09,531 [ACK]
10:38:09,640 [STX]1H|\^&|||cobasu411^8^3.2.0.1001Înt|||||
||P||20110315103928[CR][ETX]7A[CR][LF]
10:38:09,656 [ACK]
10:38:09,687 [STX]2P|1[CR][ETX]3F[CR][LF]
10:38:09,703 [ACK]
10:38:09,781 [STX]3O|1|004|4^^^^SAMPLE||R||||||X|||201103151
10:38:09,797 [ACK]
10:38:09,859 [STX]4R|1|1^SG||||||||service[CR][ETX]B9[CR][LF
]
10:38:09,875 [ACK]
10:38:09,937 [STX]5C|1|I|T|I[CR][ETX]8F[CR][LF]
10:38:09,937 [ACK]
10:38:10,015 [STX]6R|2|2^pH||||||||service[CR][ETX]DB[CR][LF
]
10:38:10,015 [ACK]
10:38:10,078 [ACK]
10:38:10,156 [STX]0R|3|3^LEU||||||||service[CR][ETX]05[CR][L
F]
10:38:10,156 [ACK]
10:38:10,218 [STX]1C|3|I|T|I[CR][ETX]8D[CR][LF]
10:38:10,218 [ACK]
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u411
Host
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Host
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Host
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Host
u411
Host
u411
Host
10:38:10,297 [STX]2R|4|4^NIT||||||||service[CR][ETX]0E[CR][L
F]
10:38:10,297 [ACK]
10:38:10,359 [ACK]
10:38:10,437 [STX]4R|5|5^PRO||||||||service[CR][ETX]18[CR][L
F]
10:38:10,453 [ACK]
10:38:10,515 [ACK]
10:38:10,593 [STX]6R|6|6^GLU||||||||service[CR][ETX]13[CR][L
F]
10:38:10,593 [ACK]
10:38:10,656 [ACK]
10:38:10,734 [STX]0R|7|7^KET||||||||service[CR][ETX]0B[CR][L
F]
10:38:10,734 [ACK]
10:38:10,797 [ACK]
10:38:10,875 [STX]2R|8|8ÛBG||||||||service[CR][ETX]09[CR][L
F]
10:38:10,875 [ACK]
10:38:10,937 [ACK]
10:38:11,000 [STX]4R|9|9^BIL||||||||service[CR][ETX]06[CR][L
F]
10:38:11,000 [ACK]
10:38:11,078 [ACK]
10:38:11,140 [STX]6R|10|10ÊRY||||||||service[CR][ETX]71[CR]
[LF]
10:38:11,156 [ACK]
10:38:11,218 [STX]7C|10|I|T|I[CR][ETX]C1[CR][LF]
10:38:11,218 [ACK]
10:38:11,297 [STX]0R|11|11^COL||||||||service[CR][ETX]5B[CR]
[LF]
10:38:11,297 [ACK]
10:38:11,359 [STX]1C|11|I|T|I[CR][ETX]BC[CR][LF]
10:38:11,359 [ACK]
[LF]
10:38:11,437 [ACK]
10:38:11,515 [STX]3M|1|RR|11^COM|blue|83.49[CR][ETX]1E[CR][L
F]
10:38:11,515 [ACK]
10:38:11,593 [STX]4M|2|RR|11^COM|green|80.23[CR][ETX]7E[CR][
LF]
10:38:11,593 [ACK]
10:38:11,672 [STX]5M|3|RR|11^COM|orange|82.25[CR][ETX]EF[CR]
[LF]
10:38:11,672 [ACK]
10:38:11,750 [STX]6M|4|RR|10ÊRY|green|78.72[CR][ETX]9D[CR][
LF]
10:38:11,765 [ACK]
[LF]
10:38:11,843 [ACK]
F]
10:38:11,922 [ACK]
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Host
u411
Host
u411
Host
F]
10:38:12,000 [ACK]
F]
10:38:12,078 [ACK]
10:38:12,156 [STX]3M|9|RR|6^GLU|green|79.73[CR][ETX]6E[CR][L
F]
10:38:12,156 [ACK]
10:38:12,234 [STX]4M|10|RR|5^PRO|orange|82.63[CR][ETX]03[CR]
[LF]
10:38:12,234 [ACK]
10:38:12,312 [STX]5M|11|RR|8ÛBG|green|80.48[CR][ETX]8B[CR][
LF]
10:38:12,312 [ACK]
LF]
10:38:12,406 [ACK]
F]
10:38:12,484 [ACK]
LF]
10:38:12,562 [ACK]
LF]
10:38:12,640 [ACK]
10:38:12,718 [STX]2M|16|RC|||2001601|20111001|||[CR][ETX]C7[
CR][LF]
10:38:12,718 [ACK]
10:38:12,765 [STX]3L|1|N[CR][ETX]06[CR][LF]
10:38:12,765 [ACK]
10:38:12,812 [EOT]

u411
Host
u411
Host
u411
Host
u411
Host
u411
Host
u411
Host
u411
Host
u411
Host
u411
Host
u411
10:08:06,437 [ENQ]
10:08:06,437 [ACK]
10:08:06,547 [STX]1H|\^&|||cobasu411^8^3.2.0.1001Înt|||||
||P||20110315100925[CR][ETX]74[CR][LF]
10:08:06,562 [ACK]
10:08:06,609 [STX]2P|1[CR][ETX]3F[CR][LF]
10:08:06,625 [ACK]
10:08:06,703 [STX]3O|1||0^^^^CONTROL||R||||||X\Q|||201103151
00924[CR][ETX]68[CR][LF]
10:08:06,718 [ACK]
R][LF]
10:08:06,812 [ACK]
F]
10:08:06,890 [ACK]
][LF]
10:08:06,968 [ACK]
][LF]
10:08:07,047 [ACK]
][LF]
10:08:07,125 [ACK]
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Host
][LF]
10:08:07,203 [ACK]
][LF]
10:08:07,281 [ACK]
][LF]
10:08:07,359 [ACK]
][LF]
10:08:07,453 [ACK]
CR][LF]
10:08:07,531 [ACK]
9[CR][LF]
10:08:07,609 [ACK]
10:08:07,703 [STX]7M|1|RC|||2001601|20111001|ctrl|123456|201
11001[CR][ETX]06[CR][LF]
10:08:07,703 [ACK]
10:08:07,750 [STX]0L|1|N[CR][ETX]03[CR][LF]
10:08:07,750 [ACK]
10:08:07,796 [EOT]

u411
Host
u411
Host
u411
Host
u411
Host
u411
Host
u411
Host
u411
Host
u411
Host
u411
Host
u411
Host
u411
Host
u411
Host
u411
10:34:59,593 [ENQ]
10:34:59,609 [ACK]
10:34:59,703 [STX]1H|\^&|||cobasu411^8^3.2.0.1001Înt|||||
||P||20110315103618[CR][ETX]76[CR][LF]
10:34:59,718 [ACK]
10:34:59,765 [STX]2P|1[CR][ETX]3F[CR][LF]
10:34:59,781 [ACK]
10:34:59,875 [STX]3O|1||0^^^^CONTROL||R||||||X\Q|||201103151
00924[CR][ETX]68[CR][LF]
10:34:59,875 [ACK]
R][LF]
10:34:59,953 [ACK]
F]
10:35:00,031 [ACK]
][LF]
10:35:00,109 [ACK]
][LF]
10:35:00,187 [ACK]
][LF]
10:35:00,265 [ACK]
][LF]
10:35:00,359 [ACK]
][LF]
10:35:00,437 [ACK]
][LF]
10:35:00,515 [ACK]
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Host
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Host
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Host
][LF]
10:35:00,593 [ACK]
CR][LF]
10:35:00,672 [ACK]
9[CR][LF]
10:35:00,750 [ACK]
10:35:00,828 [STX]7M|1|RR|11^COM|blue|74.53[CR][ETX]1D[CR][L
F]
10:35:00,828 [ACK]
LF]
10:35:00,906 [ACK]
10:35:00,984 [STX]1M|3|RR|11^COM|orange|72.37[CR][ETX]ED[CR]
[LF]
10:35:00,984 [ACK]
10:35:01,062 [STX]2M|4|RR|10ÊRY|green|68.44[CR][ETX]97[CR][
LF]
10:35:01,078 [ACK]
10:35:01,140 [STX]3M|5|RR|10ÊRY|orange|73.07[CR][ETX]FF[CR]
[LF]
10:35:01,156 [ACK]
F]
10:35:01,234 [ACK]
F]
10:35:01,312 [ACK]
F]
10:35:01,390 [ACK]
10:35:01,468 [STX]7M|9|RR|6^GLU|green|77.33[CR][ETX]6C[CR][L
F]
10:35:01,468 [ACK]
[LF]
10:35:01,547 [ACK]
LF]
10:35:01,625 [ACK]
10:35:01,703 [STX]2M|12|RR|9^BIL|green|73.60[CR][ETX]7F[CR][
LF]
10:35:01,718 [ACK]
F]
10:35:01,797 [ACK]
LF]
10:35:01,875 [ACK]
LF]
10:35:01,953 [ACK]
10:35:02,047 [STX]6M|16|RC|||2001601|20111001|ctrl|123456|20
111001[CR][ETX]3B[CR][LF]
10:35:02,047 [ACK]
10:35:02,093 [STX]7L|1|N[CR][ETX]0A[CR][LF]
10:35:02,093 [ACK]
10:35:02,140 [EOT]
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The cobas u 411 analyzer starts the request
u411
Host
u411
Host
u411
Host
u411
Host
u411
10:41:34,530 [ENQ]
10:41:34,655 [ACK]
10:41:34,686 [STX]1H|\^&|||cobasu411^8^3.2.0.1001Înt|||||
||P||20110315104252[CR][ETX]71[CR][LF]
10:41:35,061 [ACK]
10:41:35,093 [STX]2Q|1|ÂLL[CR][ETX]F3[CR][LF]
10:41:35,468 [ACK]
10:41:35,515 [STX]3L|1|N[CR][ETX]06[CR][LF]
10:41:35,874 [ACK]
10:41:35,905 [EOT]
Host sends the sample ID 012

Host
u411
Host
u411
Host
u411
Host
10:41:37,296
10:41:37,311
10:41:37,515
10:41:37,561
10:41:37,921
10:41:37,952
10:41:38,327
u411
Host
u411
Host
10:41:38,624
10:41:38,733
10:41:38,765
10:41:39,140
[ENQ]
[ACK]
[STX]1H|\^&|||Host|||||||P[CR][ETX]AB[CR][LF]
[ACK]
[STX]2P|1[CR][ETX]3F[CR][LF]
[ACK]
[STX]3O|1|012|^^^^SAMPLE||R||||||X|||2011031510
4136[CR][ETX]BE[CR][LF]
[ACK]
[STX]4L|1|N[CR][ETX]07[CR][LF]
[ACK]
[EOT]
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5.2 ASTM Urisys 2400 protocol

5.2.1 General
This chapter describes the ASTM URISYS 2400 protocol. This protocol consists of Records,
Frames and Messages.
A Record is the smallest logical group of information
A Frame is a defined data structure that contains a data block to be transmitted
Messages are a collection of several records packed in frames into a logical unit
Note: The ASTM Urisys 2400 protocol is based on the ASTM protocol specification.
Records
A record is the smallest logical group of information. The ASTM Urisys 2400 protocol supports the
following records:
Identifier
H
P
Name
Header record
Patient information
record
O
R
C
Order record
Result record
Comment record
Manufacturer record
Request information
record
Termination record
Description
First record in every message, mandatory
This record is used to download patient demographics
from the host system to the analyzer. With the cobas u
411 analyzer no patient data can be handled. Therefore
the patient record is always empty.
This record defines the attributes of a particular order.
Measurement data
This record is used for the transmission of sample flags
and result flags.
This record is used for the transmission of raw data,
additional information for patient, control results.
Worklist request (query). Not supported.
Does not exist in ASTM URISYS 2400 protocol.
Last record in every message, mandatory
Frames
A frame is a defined data structure that encapsulates a data block to be transmitted. According to
the ASTM Urisys 2400 protocol specification, a frame may contain one or more records. However,
the implementation in the cobas u 411 analyzer contains one record only. Each frame has the
following structure:
Description
ASCII
(hex)
Start of
text
STX
(0x02)
Frame
No.
Protocol
specific
record
data
End of
text
ETX
(0x03)
Checksum
Carriage
return
CR
(0x0D)
Line feed
LF
(0x0A)
The frame no. always starts at 1 and will be incremented by one for each record. If the frame
reaches no. 7, the numbering starts at 0 (zero).
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Usually, the ASTM protocol contains one record only per frame:
[STX] + Frame no. + Information (record) + [ETX] + Checksum + [CR] + [LF]
The ASTM Urisys 2400 protocol is a special implementation of ASTM. All records will be packed in
one frame. According to ASTM standard the total length of the data in one frame (message) is 247
bytes (including frame overhead). Messages longer than 240 bytes are divided into several frames,
called sub-frame. Such a sub-frame is terminated with an [ETB] character:
[STX] + Frame no. + Information 1 + [ETB] + Checksum + [CR] + [LF]
[STX] + Frame no. + Information 2 + [ETX] + Checksum + [CR] + [LF] (Msg-end, therefore [ETX])
Example:
u411
Host
10:46:36,385 [ENQ]
10:46:36,385 [ACK]
Information 1
u411
Host
10:46:36,682 [STX]1H|\^&|||8|||||||P|3.2.0.1001[CR]P|1[CR]O|
1|001|1^^^service^SAMPLE||R||||||X|||2011031510
1754[CR]R|1|^^^1|1.005|||||[CR]C|1|I||I[CR]R|2|
^^^2|7|||||[CR]C|2|I||I[CR]R|3|^^^3|NEG|||||[CR
]C|3|I||I[CR]R|4|^^^4|NEG|||||[CR]C|4|I||I[CR]R
|5|^^^5|NEG|||||[CR]C|5|I||I[CR]R|6|^^^6|NEG|||
||[CR][ETB]97[CR][LF] [ETB] Device control
10:46:36,698 [ACK]
Information 2
u411
Host
u411
10:46:36,932 [STX]2C|6|I||I[CR]R|7|^^^7|NEG|||||[CR]C|7|I||I
[CR]R|8|^^^8|NEG|||||[CR]C|8|I||I[CR]R|9|^^^9|N
EG|||||[CR]C|9|I||I[CR]R|10|^^^10|NEG|||||[CR]C
|10|I||I[CR]R|11|^^^11|p.yel|||||[CR]C|11|I||I[
CR]R|12|^^^12||||||X[CR]C|12|I||I[CR]L|1|[CR][E
TX]D3[CR][LF]
[ETX] End of text
10:46:36,932 [ACK]
10:46:36,979 [EOT]
Messages
Messages are collections of several records packed in frames into a logical unit. A message starts
with a Header Record (H) and ends with the Termination Record (L).
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5.2.2 Communication structure

Only the cobas u 411 analyzer can start a communication. The cobas u 411 analyzer is always
the master, the host system the slave.
A communication is initialized when the ASCII character ENQ
(Hex 05) is sent to the host system.
The host system (slave) acknowledges its readiness to
communicate by sending the ASCII character ACK (Hex 06) or
if it is not ready the ASCII character NAK (Hex 15).
cobas u 411
If the host system has positively acknowledged its readiness to

communicate (ACK), the cobas u 411 analyzer transmits the
message frame by frame.
The host system confirms the frame reception with ACK.
The host system can trigger a resending of the last sent frame
with NAK.
The communication session is terminated with the ASCII
character EOT (Hex 04).
V 2.1
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cobas u 411
Host
5.2.3 Record descriptions

In this chapter, the meaning of the fields in individual records will be explained in the form of tables.
Fields which are not supported by the cobas u 411 analyzer are highlighted in grey.
For a better comprehension, there is a detailed example for each record description following the
table. Example trace files of different data interchanges are added at the end of this protocol
description.
Message header record

Each message starts with the Message Header Record. This record is mandatory.
No. Field
1
Record type ID
Content
H
|
\
^
&
3
4
5
6
7
8
9
10
11
12
13
14
Field Delimiter
Repeat Delimiter
Component Delimiter
Escape Delimiter
Message control ID
Access password
Sender name or ID
Sender street address
Reserved field
Sender telephone
number
Characteristics of
sender
Receiver ID
Comment of special
instructinos
Processing ID
Version number
Date and time of
message
serial no.
Comment
The character H identifies the record as a
message header record.
Defines the delimiters to be used
throughout the subsequent records of the
message.
Serial number of the analyzer
P
software version
Always P (production)
e.g. 3.2.0.1001
Not supported and not transmitted
Example:
No:
1
2
3 4
5 6 7 8 9 10 11 12 13
CR
Content: H | \^& | | | 8 | | | | | | | P | 3.2.0.1001 [CR]
Patient information record

Although the cobas u 411 analyzer does not record any patient data, the Patient Information
Record is mandatory by the ASTM standard. For this reason the cobas u 411 analyzer transmits
an empty record.
No.
1
2
3 .. 35
Field
Record type ID
Comment
The character P identifies the record as a
patient record.
Sequence no.
1
always 1.
Content
P
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cobas u 411
Host
Example:
No:
1
2 CR
Content: P | 1 [CR]
Order record
The cobas u 411 analyzer uses the Order Record to transmit general sample information such as
sample ID, sequence no. etc.
No.
1
Field
Record type ID
Content
O
Sequence no.
Specimen ID
sample ID
Instrument
specimen ID
sample no
^rack ID
^position no.
ôperator ID
^data carrier type
5
6
Universal test ID
Priority
Request/ordered
date and time
Specimen collection
date and time
Collection end time
Collection volume
Collector ID
Action code
X or X\Q
Always X, in case of control samples X\Q
Danger code
Relevant clinical
information
Date / time
specimen received
example 20000202035009
8
9
10
11
12
13
14
15
16 .. 31
Comment
The character O identifies the record as an
order record.
always 1.
ID of the sample, numerical or
alphanumerical value (max. 13 digits)
The cobas u 411 analyzer supports only
sample no, user ID and data carrier type
(SAMPLE for patient samples, CONTROL
for control samples. For order download the
sample no is not needed and is ignored.
Always R (routine sample), the cobas u 411
analyzer does not support emergency
samples

No:
1
2
3
4
5 6 7 8 9 10 11 12 13 14
Content: O | 1 | 001 | 1^^^service^SAMPLE | | R | | | | | | X | | |
No:
15
CR
Content: 20110315101754 [CR]

No:
1
2
3 4
5
6 7 8 9 10 11 12
13 14
Content: O | 1 | | 0^^^^CONTROL | | R | | | | | | X\Q | | |
No:
15
CR
Content: 20110315100924 [CR]
V 2.1
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cobas u 411
Host
Result record
The cobas u 411 analyzer uses the Result Record to transmit the measurement data. Each test
needs a separate Result Record. Flags related to test strip error, e.g. strip upside down, are sent
in this Result Record in no. 7 and no. 9. Flags related to results are sent in the Comment Record
and must be observed.
No. Field
1 Record type ID
Content
R
2 Sequence no.
1 12
3 Universal test ID
^
^
^test no.
4 Data or
measurement value
result value
5 Unit
6 Reference ranges
7 Result abnorm. flag
8 Nature of
abnormality testing
9 Result status
10 .. 14
unit
Comment
The character R identifies the record as a
result record.
The cobas u 411 analyzer always saves 12
results (color and clarity included)
Test no list (fixation):
1: SG
2: pH
3: LEU
4: NIT
5: PRO
6: GLU
7: KET
8: UBG
9: BIL
10: ERY
11: COL
12: CLA
Result value:
Numerical value (e.g. 1.030) or
alphanumerical value (e.g. neg.)
Important: To be compatible with the
original URISYS 2400 analyzer, the following
conversions are done in the driver:
pos
POS
pos.
POS
neg
NEG
neg.
NEG
norm
NORM
norm.
NORM
Alphanumerical value (e.g. mg/dL), only if
result can be represented by several units
Important: All l letters, which stand for
liter, are converted to capital letters (e. g.
ml
mL) and character is translated to a
u character.
Flag R: Test Strip Error
Flag X: Order cannot be done. Usually, in

combination with result abnormal flag (R)
Example:
No:
1
2
3
4
5 6 7 8 9 CR
Content: R | 1 | ^^^1 | 1.005 | | | | | [CR]
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cobas u 411
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Example (test strip error: R/X-Flag):

No:
1
2
3
4 5 6
7 8
9 CR
Content: R | 2 | ^^^2 | | | | R | | X [CR]
Comment record
Every Result Record has a Comment Record attached. The cobas u 411 analyzer uses the
Comment Record to transmit the sample flags and result flags. In case of no flag, an empty
Comment Record is transmitted.
No. Field
1 Record type ID
2 Sequence no.
3 Comment source
4 Comment text
5 Comment type
Attention:
Content
C
Comment
The character C identifies the record as a
comment record.
1
The cobas u 411 analyzer uses the same
sequence number as the prior result record.
I
Always I (clinical instrument system)
Sample result flags The cobas u 411 analyzer uses the
comment record only for transmitting flags,
each flag is separated with the ^ delimiter.
I
Always I (instrument flag(s) comment)
decisions!
Read the chapter 2.4 Flags for detailed information!
Example (result record and comment record
no flag):
Content: R|2|^^^2|7|||||[CR]
Result record
No:
1
2
3 4
5 CR
Content: C | 2 | I | | I [CR]
Comment record without flags

Content: R|2|^^^2|6|||||[CR]
No:
1
2
3
4
5 CR
Content: C | 2 | I | ! | I [CR]

Content: R|2|^^^2|8|||||[CR]
No:
1
2
3
4
5 CR
Content: C | 2 | I | *^S | I [CR]

Content: R|2|^^^2||||R||X[CR]
No:
1
2
3
4 5 CR
Content: C | 2 | I | | I [CR]
edited result: !-flag:):

Result record
Comment record with flags
abnormal and sieve: *-flag and S-flag):

Result record
Comment record with flags
test strip error: R/X-flag):

Result record with flags
Comment Record without flags
V 2.1
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cobas u 411
Host
Manufacturer record (raw result record - RR)

The cobas u 411 analyzer uses the Manufacturer Record RR to transmit raw data for special
application (e.g. evaluation / research). It is possible to activate this application via the user
interface (Utilities / Tools2 / Service Raw Data to Host
ON)
No. Field
1 Record type ID
Content
M
2 Sequence no.
1 16
3 Record type sub-ID

4 Raw result value
RR
Reflectance
Comment
The character M identifies the record as a
manufacturer record.
The cobas u 411 analyzer determines
always 16 results, running number
Always RR (raw result)
floating number in the format ##.## (e.g.
88.06) fix order for raw result value:
1: COM blue
2: COM green
3: COM orange
4: ERY green
5: ERY orange
6: LEU green
7: NIT green
8: KET green
9: GLU green
10: PRO orange
11: UBG green
12: BIL green
13: pH green
14: pH orange
15: SG orange
16: not used, always 0
Example:
No:
1
2
3
4
CR
Content: M | 1 | RR | 78.19 | [CR]
Manufacturer record (result context record - RC)

The cobas u 411 analyzer uses the Manufacturer Record RC to transmit the control name as
well as the control lot number.
No. Field
1 Record type ID
2
3
4
5
Sequence no.
Record type sub-ID
Test strip cassette lot number
Date / time test strip cassette
set
6 Control name
7 Control identifier
Content
M
1
RC
e.g. Ctrl
e.g. 123456
Comment
The character M identifies the record
as a manufacturer record.
Running number
Always RC (result context)
Always empty
Always empty
Control name
Control lot no
Example:
No:
1
2
3
4 5
6
7
CR
Content: M | 1 | RC | | | ctrl | 123456 | [CR]
V 2.1
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cobas u 411
Host
Termination record
Each message is closed with the Message Terminator Record. This record is mandatory.
No. Field
1 Record type ID
2 Sequence no.
3 Termination code
Content
L
1
Comment
The character L identifies the record
as a message terminator record.
Per definition always 1
Empty if normal end of message
Example:
No:
1
2
3 CR
Content: L | 1 |
[CR]
Scientific Record
This type of record is not used in cobas u 411 analyzer (the character S would identify the record
as a scientific record).
V 2.1
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cobas u 411
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5.2.4 ASTM Urisys 2400 trace file examples

- Sample 1
- Sample 3 (with *- and S-flag for pH)
- Sample 1
- Sample 3 (with *- and S-flag for pH)

Sample 1
u411
Host
u411
Host
u411
Host
u411
10:46:36,385 [ENQ]
10:46:36,385 [ACK]
10:46:36,682 [STX]1H|\^&|||8|||||||P|3.2.0.1001[CR]P|1[CR]O|
1754[CR]R|1|^^^1|1.005|||||[CR]C|1|I||I[CR]R|2|
^^^2|7|||||[CR]C|2|I||I[CR]R|3|^^^3|NEG|||||[CR
|5|^^^5|NEG|||||[CR]C|5|I||I[CR]R|6|^^^6|NEG|||
||[CR][ETB]97[CR][LF]
10:46:36,698 [ACK]
|10|I||I[CR]R|11|^^^11|p.yel|||||[CR]C|11|I||I[
CR]R|12|^^^12||||||X[CR]C|12|I||I[CR]L|1|[CR][E
TX]D3[CR][LF]
10:46:36,932 [ACK]
10:46:36,979 [EOT]

u411
Host
u411
Host
u411
11:02:07,436 [ENQ]
11:02:07,436 [ACK]
11:02:07,733 [STX]1H|\^&|||8|||||||P|3.2.0.1001[CR]P|1[CR]O|
2140[CR]R|1|^^^1|1.010|||||[CR]C|1|I||I[CR]R|2|
^^^2|6|||||[CR]C|2|I|!|I[CR]R|3|^^^3|NEG|||||[C
R]C|3|I||I[CR]R|4|^^^4|NEG|||||[CR]C|4|I||I[CR]
R|5|^^^5|NEG|||||[CR]C|5|I||I[CR]R|6|^^^6|NEG||
|||[ETB]9E[CR][LF]
11:02:07,748 [ACK]
11:02:07,983 [STX]2[CR]C|6|I||I[CR]R|7|^^^7|NEG|||||[CR]C|7|
I||I[CR]R|8|^^^8|NEG|||||[CR]C|8|I||I[CR]R|9|^^
^9|NEG|||||[CR]C|9|I||I[CR]R|10|^^^10|NEG|||||[
CR]C|10|I||I[CR]R|11|^^^11|p.yel|||||[CR]C|11|I
||I[CR]R|12|^^^12||||||X[CR]C|12|I||I[CR]L|1|[C
R][ETX]E0[CR][LF]
V 2.1
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cobas u 411
Host
u411
Host
11:02:07,983 [ACK]
11:02:08,029 [EOT]
Sample 3 (with *- and S-flag for pH)

u411
Host
u411
Host
u411
Host
u411
10:48:02,056 [ENQ]
10:48:02,056 [ACK]
10:48:02,353 [STX]1H|\^&|||8|||||||P|3.2.0.1001[CR]P|1[CR]O|
2801[CR]R|1|^^^1|1.010|||||[CR]C|1|I||I[CR]R|2|
^^^2|8|||||[CR]C|2|I|*^S|I[CR]R|3|^^^3|NEG|||||
[CR]C|3|I||I[CR]R|4|^^^4|NEG|||||[CR]C|4|I||I[C
R]R|5|^^^5|NEG|||||[CR]C|5|I||I[CR]R|6|^^^6|NEG
|||[ETB]68[CR][LF]
10:48:02,353 [ACK]
10:48:02,587 [STX]2||[CR]C|6|I||I[CR]R|7|^^^7|NEG|||||[CR]C|
7|I||I[CR]R|8|^^^8|NEG|||||[CR]C|8|I||I[CR]R|9|
^^^9|NEG|||||[CR]C|9|I||I[CR]R|10|^^^10|NEG||||
|[CR]C|10|I||I[CR]R|11|^^^11|p.yel|||||[CR]C|11
|I||I[CR]R|12|^^^12||||||X[CR]C|12|I||I[CR]L|1|
[CR][ETX]D8[CR][LF]
10:48:02,603 [ACK]
10:48:02,634 [EOT]

u411
Host
u411
Host
u411
Host
u411
10:48:41,159 [ENQ]
10:48:41,159 [ACK]
10:48:41,456 [STX]1H|\^&|||8|||||||P|3.2.0.1001[CR]P|1[CR]O|
3316[CR]R|1|^^^1||||R||X[CR]C|1|I||I[CR]R|2|^^^
2||||R||X[CR]C|2|I||I[CR]R|3|^^^3||||R||X[CR]C|
3|I||I[CR]R|4|^^^4||||R||X[CR]C|4|I||I[CR]R|5|^
^^5||||R||X[CR]C|5|I||I[CR]R|6|^^^6||||R||X[CR]
C|6|I|[ETB]38[CR][LF]
10:48:41,471 [ACK]
10:48:41,706 [STX]2|I[CR]R|7|^^^7||||R||X[CR]C|7|I||I[CR]R|8
|^^^8||||R||X[CR]C|8|I||I[CR]R|9|^^^9||||R||X[C
R]C|9|I||I[CR]R|10|^^^10||||R||X[CR]C|10|I||I[C
R]R|11|^^^11||||R||X[CR]C|11|I||I[CR]R|12|^^^12
||||R||X[CR]C|12|I||I[CR]L|1|[CR][ETX]F1[CR][LF
]
10:48:41,706 [ACK]
10:48:41,753 [EOT]

Sample 1
u411
Host
u411
10:50:41,013 [ENQ]
10:50:41,029 [ACK]
10:50:41,326 [STX]1H|\^&|||8|||||||P|3.2.0.1001[CR]P|1[CR]O|
1754[CR]R|1|^^^1|1.005|||||[CR]C|1|I||I[CR]R|2|
^^^2|7|||||[CR]C|2|I||I[CR]R|3|^^^3|NEG|||||[CR
|5|^^^5|NEG|||||[CR]C|5|I||I[CR]R|6|^^^6|NEG|||
V 2.1
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cobas u 411
Host
u411
Host
u411
Host
u411
Host
||[CR][ETB]97[CR][LF]
10:50:41,326 [ACK]
|10|I||I[CR]R|11|^^^11|p.yel|||||[CR]C|11|I||I[
CR]R|12|^^^12||||||X[CR]C|12|I||I[CR]M|1|RR|78.
19|[CR]M|2|RR|76.80|[CR]M|3|RR|76.23|[CR]M|4|RR
|69.07|[CR]M|5|[ETB]6F[CR][LF]
10:50:41,622 [ACK]
10:50:41,857 [STX]3RR|73.75|[CR]M|6|RR|77.50|[CR]M|7|RR|77.3
|70.13|[CR]M|11|RR|75.19|[CR]M|12|RR|74.79|[CR]
M|13|RR|36.18|[CR]M|14|RR|25.07|[CR]M|15|RR|06.
51|[CR]M|16|RR|0|[CR]L|1|[CR][ETX]70[CR][LF]
10:50:41,857 [ACK]
10:50:41,904 [EOT]

u411
Host
u411
Host
u411
Host
u411
Host
u411
10:58:40,529 [ENQ]
10:58:40,529 [ACK]
10:58:40,826 [STX]1H|\^&|||8|||||||P|3.2.0.1001[CR]P|1[CR]O|
2140[CR]R|1|^^^1|1.010|||||[CR]C|1|I||I[CR]R|2|
^^^2|6|||||[CR]C|2|I|!|I[CR]R|3|^^^3|NEG|||||[C
R]C|3|I||I[CR]R|4|^^^4|NEG|||||[CR]C|4|I||I[CR]
R|5|^^^5|NEG|||||[CR]C|5|I||I[CR]R|6|^^^6|NEG||
|||[ETB]9E[CR][LF]
10:58:40,826 [ACK]
10:58:41,138 [STX]2[CR]C|6|I||I[CR]R|7|^^^7|NEG|||||[CR]C|7|
I||I[CR]R|8|^^^8|NEG|||||[CR]C|8|I||I[CR]R|9|^^
^9|NEG|||||[CR]C|9|I||I[CR]R|10|^^^10|NEG|||||[
CR]C|10|I||I[CR]R|11|^^^11|p.yel|||||[CR]C|11|I
||I[CR]R|12|^^^12||||||X[CR]C|12|I||I[CR]M|1|RR
|77.14|[CR]M|2|RR|75.73|[CR]M|3|RR|74.93|[CR]M|
4|RR|66.56|[CR]M|5[ETB]01[CR][LF]
10:58:41,138 [ACK]
10:58:41,357 [STX]3|RR|65.93|[CR]M|6|RR|77.83|[CR]M|7|RR|78.
86|[CR]M|8|RR|61.32|[CR]M|9|RR|78.04|[CR]M|10|R
R|70.10|[CR]M|11|RR|75.26|[CR]M|12|RR|74.40|[CR
]M|13|RR|35.32|[CR]M|14|RR|24.09|[CR]M|15|RR|05
.68|[CR]M|16|RR|0|[CR]L|1|[CR][ETX]E1[CR][LF]
10:58:41,357 [ACK]
10:58:41,404 [EOT]
Sample 3 (with *- and S-flag for pH)

u411
Host
u411
Host
u411
10:51:28,177 [ENQ]
10:51:28,177 [ACK]
10:51:28,474 [STX]1H|\^&|||8|||||||P|3.2.0.1001[CR]P|1[CR]O|
2801[CR]R|1|^^^1|1.010|||||[CR]C|1|I||I[CR]R|2|
^^^2|8|||||[CR]C|2|I|*^S|I[CR]R|3|^^^3|NEG|||||
[CR]C|3|I||I[CR]R|4|^^^4|NEG|||||[CR]C|4|I||I[C
R]R|5|^^^5|NEG|||||[CR]C|5|I||I[CR]R|6|^^^6|NEG
|||[ETB]68[CR][LF]
10:51:28,474 [ACK]
10:51:28,771 [STX]2||[CR]C|6|I||I[CR]R|7|^^^7|NEG|||||[CR]C|
V 2.1
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cobas u 411
Host
u411
10:51:28,786
10:51:29,021
Host
u411
10:51:29,021
10:51:29,067
Host
7|I||I[CR]R|8|^^^8|NEG|||||[CR]C|8|I||I[CR]R|9|
^^^9|NEG|||||[CR]C|9|I||I[CR]R|10|^^^10|NEG||||
|[CR]C|10|I||I[CR]R|11|^^^11|p.yel|||||[CR]C|11
|I||I[CR]R|12|^^^12||||||X[CR]C|12|I||I[CR]M|1|
RR|74.73|[CR]M|2|RR|73.65|[CR]M|3|RR|73.35|[CR]
M|4|RR|68.63|[CR]M[ETB]44[CR][LF]
[ACK]
[STX]3|5|RR|73.44|[CR]M|6|RR|76.22|[CR]M|7|RR|7
7.83|[CR]M|8|RR|62.44|[CR]M|9|RR|79.26|[CR]M|10
|RR|70.25|[CR]M|11|RR|74.40|[CR]M|12|RR|74.32|[
CR]M|13|RR|35.36|[CR]M|14|RR|24.20|[CR]M|15|RR|
05.15|[CR]M|16|RR|0|[CR]L|1|[CR][ETX]81[CR][LF]
[ACK]
[EOT]

u411
Host
u411
Host
u411
Host
u411
Host
u411
10:51:43,737 [ENQ]
10:51:43,737 [ACK]
10:51:44,034 [STX]1H|\^&|||8|||||||P|3.2.0.1001[CR]P|1[CR]O|
3316[CR]R|1|^^^1||||R||X[CR]C|1|I||I[CR]R|2|^^^
2||||R||X[CR]C|2|I||I[CR]R|3|^^^3||||R||X[CR]C|
3|I||I[CR]R|4|^^^4||||R||X[CR]C|4|I||I[CR]R|5|^
^^5||||R||X[CR]C|5|I||I[CR]R|6|^^^6||||R||X[CR]
C|6|I|[ETB]38[CR][LF]
10:51:44,034 [ACK]
10:51:44,346 [STX]2|I[CR]R|7|^^^7||||R||X[CR]C|7|I||I[CR]R|8
|^^^8||||R||X[CR]C|8|I||I[CR]R|9|^^^9||||R||X[C
R]C|9|I||I[CR]R|10|^^^10||||R||X[CR]C|10|I||I[C
R]R|11|^^^11||||R||X[CR]C|11|I||I[CR]R|12|^^^12
||||R||X[CR]C|12|I||I[CR]M|1|RR|83.49|[CR]M|2|R
R|80.23|[CR]M|3|RR|82.25|[CR]M|4|RR|78.72|[CR]M
|5|RR|81.64|[CR]M|[ETB]F8[CR][LF]
10:51:44,346 [ACK]
10:51:44,565 [STX]36|RR|81.78|[CR]M|7|RR|80.56|[CR]M|8|RR|75
.75|[CR]M|9|RR|79.73|[CR]M|10|RR|82.63|[CR]M|11
|RR|80.48|[CR]M|12|RR|79.14|[CR]M|13|RR|75.16|[
CR]M|14|RR|80.71|[CR]M|15|RR|73.00|[CR]M|16|RR|
0|[CR]L|1|[CR][ETX]05[CR][LF]
10:51:44,565 [ACK]
10:51:44,612 [EOT]

u411
Host
u411
Host
u411
10:45:58,677 [ENQ]
10:45:58,677 [ACK]
10:45:58,974 [STX]1H|\^&|||8|||||||P|3.2.0.1001[CR]P|1[CR]O|
1||0^^^^CONTROL||R||||||X\Q|||20110315100924[CR
]R|1|^^^1|1.010|||||[CR]C|1|I||I[CR]R|2|^^^2|8|
||||[CR]C|2|I||I[CR]R|3|^^^3|NEG|||||[CR]C|3|I|
|I[CR]R|4|^^^4|NEG|||||[CR]C|4|I||I[CR]R|5|^^^5
|NEG|||||[CR]C|5|I||I[CR]R|6|^^^6|NEG|||||[CR]C
|6|I||[ETB]CD[CR][LF]
10:45:58,974 [ACK]
10:45:59,208 [STX]2I[CR]R|7|^^^7|NEG|||||[CR]C|7|I||I[CR]R|8
|^^^8|NEG|||||[CR]C|8|I||I[CR]R|9|^^^9|NEG|||||
[CR]C|9|I||I[CR]R|10|^^^10|NEG|||||[CR]C|10|I||
I[CR]R|11|^^^11|p.yel|||||[CR]C|11|I||I[CR]M|1|
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u411
Host
RC|||ctrl|123456|[CR]L|1|[CR][ETX]E3[CR][LF]
10:45:59,208 [ACK]
10:45:59,255 [EOT]

u411
Host
u411
Host
u411
Host
u411
Host
u411
10:50:08,925 [ENQ]
10:50:08,925 [ACK]
10:50:09,222 [STX]1H|\^&|||8|||||||P|3.2.0.1001[CR]P|1[CR]O|
1||0^^^service^CONTROL||R||||||X\Q|||2011031510
0924[CR]R|1|^^^1|1.010|||||[CR]C|1|I||I[CR]R|2|
^^^2|8|||||[CR]C|2|I||I[CR]R|3|^^^3|NEG|||||[CR
|5|^^^5|NEG|||||[CR]C|5|I||I[CR]R|6|^^^6|NEG|||
||[CR][ETB]0C[CR][LF]
10:50:09,222 [ACK]
|10|I||I[CR]R|11|^^^11|p.yel|||||[CR]C|11|I||I[
CR]M|1|RR|74.53|[CR]M|2|RR|73.39|[CR]M|3|RR|72.
|76.90|[CR]M|7|[ETB]0B[CR][LF]
10:50:09,534 [ACK]
10:50:09,753 [STX]3RR|78.11|[CR]M|8|RR|62.41|[CR]M|9|RR|77.3
3|[CR]M|10|RR|70.10|[CR]M|11|RR|74.08|[CR]M|12|
RR|73.60|[CR]M|13|RR|32.52|[CR]M|14|RR|21.44|[C
R]M|15|RR|05.43|[CR]M|16|RR|0|[CR]M|17|RC|||ctr
l|123456|[CR]L|1|[CR][ETX]9F[CR][LF]
10:50:09,753 [ACK]
10:50:09,800 [EOT]

ASTM Urisys 2400 protocol doesnt support worklist download
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6 Appendices
6.1 Appendix 1: ASCII-table
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6.2 Appendix 2: Definition of test codes and test numbers

(for ASTM plus protocol only)
Parameter
Test code
Test number
Specific Gravity
pH-value
Leukocytes
Nitrite
Protein
Glucose
Ketones
Urobilinogen
Bilirubin
Erythrocytes
Compensation pad
Color
Clarity
Sediment Parameter 1
SG
pH
LEU
NIT
PRO
GLU
KET
UBG
BIL
ERY
COM
COL
CLA
Name 1. Sediment Parameter

1
2
3
4
5
6
7
8
9
10
11
12
13
51
52
53
54
55
56
57
58
59
60
61
62
63
64
65
66
67
68
69
70
71
72
73
74
75
76
77
78
79
80
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6.3 Appendix 3: Printouts of control and sample results

Sample Result - Sample 1

with !-flag for pH

with *- and S-flag for pH
and sediment data for ERY and LEU

with T-flag
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Control Result
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Host Interface Manual - U411 PDF

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Roche Diagnostics AG

cobas u 411 Host Interface Manual

ROCHE DIAGNOSTICS MAKES NO REPRESENTATIONS OR WARRANTIES WITH RESPECT

COPYRIGHT 2011, BY ROCHE DIAGNOSTICS. ALL RIGHTS RESERVED. NO PART OF THIS

cobas u 411 Host Interface Manual

cobas u 411 Host Interface Manual

1.1 Document structure

1.3 Related documents

1.4 Used syntax and abbreviations

Meaning any string (not containing delimiters), representing a

cobas u 411 Host Interface Manual

American Society for Testing and Materials

cobas u 411 Host Interface Manual

2.1 Overview cobas u 411 analyzer

2.2 Supported host protocols

2.3 Sample ID length

cobas u 411 Host Interface Manual

Additional flags for ASTM Urisys 2400 protocol only

Order cannot be done

cobas u 411 Host Interface Manual

2.5 Upload (cobas u 411 to host system)

Sample ID / Sequence number

ASTM Urisys 2400

ASTM Urisys 2400

Name and lot ID

cobas u 411 Host Interface Manual

ASTM plus protocol

ASTM Urisys 2400

2.6 Arbitrary units

cobas u 411 Host Interface Manual

2.7 Download data (host system to cobas u 411)

3 Host interface configuration

3.1 Communication settings

1200, 2400, 4800, 9600, 19200, 38400, 57600

None, Xon-Xoff, RTS-CTS

None, odd, even

3.2 Host interface behaviour

ASTM plus, ASTM Urisys 2400

Raw data to host

OFF, ON, upload only (setup in service)

3.3 Serial cable

4 Error handling (behaviour of a failed transmission)

Host receives wrong data:

cobas u 411 Host Interface Manual

5 Description of the supported protocols

cobas u 411 Host Interface Manual

5.1.2 Communication startup

If the host system has positively acknowledged its readiness to

cobas u 411 Host Interface Manual

5.1.3 Record description

Message header record

Sender street address

Not used in cobas u 411 analyzer

Not used in cobas u 411 analyzer

cobas u 411 Host Interface Manual

Patient information record

cobas u 411 Host Interface Manual

Example patient sample:

Example control sample:

Result abnormal flag

cobas u 411 Host Interface Manual

Example (result record with additional comment record

edited result: !-Flag):