Brand Name: Celebrex

Generic Name: Celecoxib

Indications: Acute or chronic use in the treatment of the sings and symptoms of
osteoarthritis and RA. Management and treatment of post-surgical or dental
pain, acute pain and primary dysmenorrhea.
Drug Classification: Antirheumatic, Anti-inflammatory Analgesic
Mechanism of Action: Thought to inhibit prostaglandin synthesis, impeding
cyclooxygenase-2 to produce anti-inflammatory, analgesic, and anti-pyretic
effects.
Dosage: Oseoarthritis Adult 200mg as a single dose or a 2 divided doses. RA 100-200 mg
bid. post-surgical or dental pain, acute flare pain of osteoarthritis 200mg od or
bid.
Special Precaution: Asthma, urticaria or acute rhinitis. Children <18y/o, pregnancy,
lactation, severe hepatic impairment.
Pregnancy Risk: C, D in 3rd trimester
Adverse Reaction: GI complaints, dizziness, bronchitis, coughing, pharyngitis, rhinitis,
sinusitis, upper resp tract infection, headache, accidental injury, flu-like
symptoms, peripheral edema.
Contraindications: Hypersensitivity to drugs, severe hepatic impairment, 3rd trimester of
pregnancy.
Form: Capsules 200 and 300mg
Nursing Responsibilities:
 Tell patient to report history of allergic reactions to sulfonamides, aspirin,
NSAID’s.
 Instruct patient to report signs of GI bleeding.
 Advice patient to immediately report rash, unexplaines weight gain, or swelling.
 Inform patient that it may take several days before he feels consistent pain relief.