Sie sind auf Seite 1von 4

The Importance

of Nutritional
Treatment
By Nancy Mullan, MD

D
uring the last third of the twentieth medicine that biomedical treatments today Nancy Mullan received a degree in
century, several groups were face, even though the cures were sometimes medicine from Tufts University School
competing for dominance in the dramatic. Many patients with profound of Medicine in Boston. She completed
treatment of psychiatric disorders. For disorders experienced a degree of healing a residency in psychiatry and
more than fifty years, psychoanalysis, unheard of in mainstream practice, while fellowship in child psychiatry at the
developed by Sigmund Freud, had held generally avoiding the bizarre and often University of Chicago Hospitals and
Clinics and began a private practice
that place. Now, however, the limits of permanent side effects associated with
in adult and child psychiatry. During
early psychoanalysis had been reached. long-term drug treatment. When Hoffer’s
this time she attended the Chicago
By the mid-1960s, behaviorists, cognitive work was acknowledged at all, the response Institute for Psychoanalysis and was
psychologists, learning theorists, and was that the patients had had a spontaneous an associate attending physician
proponents of pharmacologic therapies had remission, or that they had been at Michael Reese Hospital and
come into prominence in respected academic misdiagnosed and had not had schizophrenia Medical Center. She became a clinical
settings. Freud himself had predicted that in the first place. Most frequently, his instructor in psychosomatic medicine
biologic treatments would replace the nutritional treatments were just ignored. at the Psychosomatic and Psychiatric
“talking cure.” By the end of the twentieth There is no question that pharmacologic Institute for Research and Training at
century, psycho-pharmacology dominated therapies can reduce the symptoms of Michael Reese Hospital.
the treatment of mental disorders. thought, mood, and behavior disorder After coming to Los Angeles, Dr.
Pharmaceuticals were the biologic quickly. They keep patients comfortable Mullan joined the medical staff at
treatment of choice of the mainstream for and, for the most part, out of the hospital. Cedars-Sinai Medical Center and was
psychiatric syndromes. Autism and ADD/ With the advent of the first anti-psychotic a clinical instructor at the University
of California at Los Angeles School of
ADHD have traditionally been considered medications in 1953, the major tranquilizers,
Medicine. She became an attending
psychiatric disorders and were treated patients came streaming out of the wards of
physician at Providence-Saint Joseph
by child psychiatrists. Initially autism was state mental hospitals where they had been Medical Center in Burbank where she
thought to be psychological as were all housed, sometimes for most of their lives. pursued her long-standing interest in
of the other psychiatric syndromes. But The most seriously affected, usually without psychosomatic medicine. In 1988 she
as psychiatric syndromes came to be money or family, were most often found in matriculated at the Psychoanalytic
seen as organic brain disorders instead of the streets or in shelters, shifting the burden Center of California from which she
psychological phenomena, autism spectrum for their care from the state to the individual earned Psychoanalytic Certification. In
disorders were also viewed as disorders themselves, private charitable organizations, 1989 she began to practice nutritional
of the brain, and the search began for a and local municipalities. These individuals’ medicine. In 1995 she taught in the
pharmacologic cure for autism. problems had not been solved. They had Department of Family Medicine at
Few academicians, professors of become quieter and easier to manage with the University of Southern California
psychiatry at prestigious universities, knew medication, but very few were returned to School of Medicine in Los Angeles. In
or cared that also during the 1960s, Abram society as functioning members. 1997 she joined the American College
for the Advancement of Medicine.
Hoffer, MD, PhD, was conducting the first The major problem with pharmacologic
Currently, Dr. Mullan is practicing
double-blind controlled studies of very therapy is its side effects. Side effects
nutritional medicine and psychiatry in
high doses of niacin, vitamin B-3, for the are dose related and can be horrendous. Burbank, California, treating children
treatment of psychotic thought disorder. Hoffer, whose work has been with the most on the autism spectrum and adults
Hoffer’s nutritional therapies received difficult of all mental disorders to treat, with physiologically-based emotional
the same lack of regard from mainstream schizophrenia and other psychotic thought disorders.
ISSUE 32 2009 REPRINTED WITH PERMISSION © THE AUTISM FILE www.autismfile.com | THE AUTISM FILE 27
BIOMEDICAL

orthomolecular therapy keeps the patient


The major problem with pharmacologic well.”
Hoffer considers the patient well “When
therapy is its side effects. they are free of symptoms and signs,
and getting on well with their family and
community. They are doing what they
would have done had they not become ill,
and they are…working and paying income
tax. Few orthodox tranquilized patients can
earn enough money to owe income tax.” He
further states that, “Each new schizophrenic
patient, whether left untreated or treated
by drugs alone, will cost society two million
dollars over their lifetime. A patient who
has recovered will cost society nothing and
will, on the contrary, be a contributor. The
savings can be enormous.”
The savings in human suffering are
even greater. The patient with a thought,
mood, or behavior disorder has an intense
longing to function normally. The disorder
can totally destroy their lives as they have
known it. Parents of children affected with
autism and ADD/ADHD also experience this
longing, and some have sacrificed a great
Dr. Mullan and her assistants deal in order to bring normal function about.
Autism is considered a childhood psychosis.
disorders, asserts that pharmacotherapy of the offending pharmaceutical, start a The major tranquilizer, Risperdal, a later
essentially changes a schizophrenic new medication, or eventually remove the version of the early anti-psychotics with
psychosis into a tranquilizer psychosis. He medication entirely. Patients feel better as fewer side effects, is the only FDA approved
describes this iatrogenic psychosis as being they start to be relieved of the tranquilizer medication for autism, although many anti-
“Characterized by psychological and physical psychosis, but the original psychosis depressants and other medications have
changes. Usually the visions and/or voices emerges once again, and medication is also been used. In the hope of finding a
are reduced in frequency and intensity, re-started. The patient goes back and more acceptable solution to the problems of
but sometimes they are induced. Patients forth between the two states and never autism and ADD/ADHD than medications—
become apathetic and disinterested. They progresses out of the disability. which are not satisfactory as they do
find it difficult to remember, and find it Hoffer points out the sharp contrast not make the patient really normal—
almost impossible to learn. They certainly between this situation and patients who parents are using biomedical approaches
cannot continue any educational career. have been treated nutritionally. “Drugs have that are directly derived from Hoffer’s
On the physical side, they develop tremors, the advantage that they work quickly and recommendations.
often tardive dyskinesia, hormone changes, the major disadvantage that they induce Brilliant and hardworking, Hoffer
frigidity or impotence and weight gain…. the iatrogenic psychosis. Orthomolecular continued his research and only later was
Patients prefer to be free of the side effects [nutritional] therapy has the disadvantage joined by others. The recommendations for
even if it means becoming psychotic again. that it works more slowly, but the advantage treatment expanded. The use of four-day
As a result, parenteral [injected] drugs that it does not replace one psychosis water fasts and elimination diets led to
[became] very popular….” with another. As it is often important, the discovery that certain foods or other
Hoffer describes what he calls the and sometimes critical, for the patient to ingested substances caused cerebral allergy,
tranquilizer dilemma. He recognizes that improve during early treatment, the solution brain symptoms that disappeared when
pharmacologic agents for psychotic thought is to take advantage of both regimens. A the allergenic stimulators were eliminated.
disorders do make patients better. But they combination of orthomolecular and standard Gluten and casein alone were found to be
also make normal people sick, so that as the therapy allows patients to respond more responsible for one in twenty-five cases
patient begins to recover, the closer they quickly. As they begin to improve, the drug of psychotic thought disorder. Vitamin
get to normal, the more likely the drug is is slowly withdrawn while maintaining the deficiencies were corrected. Identification
to make them sick. The natural psychosis nutrients…. Finally the drug is completely and treatment of vitamin dependency was
has been converted into a tranquilizer withdrawn, or the amount of the drug is accomplished. Amino acid and essential
psychosis. Psychiatrists often lower the dose so low that there are no side effects. The fatty acid deficiencies were addressed, as
28 THE AUTISM FILE | www.autismfile.com REPRINTED WITH PERMISSION © THE AUTISM FILE ISSUE 32 2009
Diet is foundational. A symptom which is being caused by a food or a substance
the patient is ingesting will not resolve until that substance is removed. The foods
chosen should have nutritional value, be organic, be free of chemicals, additives,
preservatives, and other pollutants, and be eaten in the least processed form possible.

were mineral deficiencies. Toxic reactions to Pfeiffer’s premature death ended his simply is opposed to vitamin or nutritional
heavy metals were identified and treated. prolific contributions and was a grave loss to support). At home, the patient may not
An Orthomolecular Psychiatric Society was early orthomolecular psychiatry. However, want to change his diet to avoid gluten,
formed and a Journal of Orthomolecular Dr. William Walsh carried on his work. He casein, or other allergenic substances. He
Psychiatry published. The foundation for founded the Pfeiffer Treatment Center may refuse to take supplements or not be
the biomedical treatment of psychiatric/ that used concepts and treatments directly able to understand why an intervention
neurologic disorders, including autism and derived from Pfeiffer’s protocols. Dr. Walsh that gives him transitory symptoms is still a
ADD/ADHD, was being laid. was present at the early Defeat Autism good idea. The patient and his caregiver will
Carl C. Pfeiffer, MD, deserves particular Now! meetings and directly communicated get no support whatever from mainstream
mention. His attention was drawn to the the ideas and protocols of Hoffer, Pfeiffer, personnel, who will only want to be sure
fact that certain individuals had high and other orthomolecular clinicians to the that medications are being taken. It will be
histamine levels in their blood, and others emerging specialists in the biomedical very uphill work for the caregiver. Patients
low. He called the high histamine patients treatment of autism and ADD/ADHD. Walsh who are in touch with reality can take care
histadelics, and the low, histapenics. called particular attention to reduced heavy of themselves and have chosen nutritional
He characterized the morphologic, metal excretion secondary to reduced intervention have much greater possibility
symptomatic, and biochemical aspects of production of metallothionine, an important for recovery.
both groups. He defined the nutritional heavy metal detox antioxidant, in the Diet is foundational. A symptom which is
support that would benefit the two differing etiology of ASD. He conveyed a great deal being caused by a food or a substance the
types. The metabolism of histamine of information about copper and zinc, their patient is ingesting will not resolve until that
involves methylation, the transfer of a proper ratio in the body, their role in metal substance is removed. The foods chosen
methyl group, a molecule with one carbon detoxification, and the role of high copper should have nutritional value, be organic, be
and three hydrogen atoms. Methylation is levels in producing depression and other free of chemicals, additives, preservatives,
currently recognized as a central process in psychiatric symptoms. and other pollutants, and be eaten in the
neurologic function and is being intensively The Nobel Laureate, Linus Pauling, also least processed form possible. Double
studied. Methylation is important for focus deserves mention. He gave the developing handfuls of nutritional supplements can be
and attention, the silencing of DNA that field of nutritional medicine the name negated by poor food choice or quality. High
should not be expressing, neurotransmitter orthomolecular, meaning right molecule. glycemic index foods should be avoided
formation and deactivation, and the proper He discerned that the right molecules as blood sugar fluctuations are a common
function of the cell membrane of the supplied to the body’s biochemistry would cause of psychiatric symptoms of all
neuron, among other things. generate right function and promote well- varieties, especially in the bipolar individual.
Pfeiffer’s work pointed to the importance being. He was a proponent of high doses of The environment inside of the patient’s
of the methionine cycle and its function, ascorbic acid and described its antioxidant, gastrointestinal (GI) tract should be
the production of methyl groups, on antiviral, and antitoxic properties. Pauling’s normalized. There should be optimal
neurologic processes. The administration involvement with nutritional therapies quantities of beneficial flora, and he or she
of methyl B-12 by injection has been vital ultimately led to his fall from grace with the should be free of pathologic bacteria, yeast
to the function of many patients. His work mainstream, but he maintained his important overgrowth, and parasites. The patient may
also supported the possibility that hydroxy role in orthomolecular circles. need digestive enzymes, probiotics, or other
B-12 might be necessary for other patients There are lesser and greater psychiatric GI environment support. Seventy percent of
who could not tolerate many methyl groups. disorders that may involve a lesser or the immune system is located in the GI tract,
Pfeiffer also characterized certain patients greater degree of intervention. The less which harbors over 400 species of bacteria
who excreted high quantities of zinc and able a patient is to understand what is and other organisms. It is the perfect setting
vitamin B-6 in their urine, and he gave being recommended and give consent to for immune system suppression and the
zinc its position as a central element in the intervention, the more difficult the seeding of systemic infection of all varieties.
nutritional protocols intended to enhance intervention becomes. While a patient is in a The gut-brain connection has been widely
neurologic function. He also called attention psychiatric hospital, nutritional intervention acknowledged: abnormalities in the GI tract
to the role of blood sugar swings in the is impossible (e.g., these hospitals will never environment may cause abnormalities in
production of neurologic/psychiatric do a gf/cf diet, the vending machines are thinking, mood, energy levels, or behavior.
symptoms. full of unhealthful items, and the staff The role of pathogenic bacteria in
ISSUE 32 2009 REPRINTED WITH PERMISSION © THE AUTISM FILE www.autismfile.com | THE AUTISM FILE 29
BIOMEDICAL

producing abnormal behavior is just starting hormones working together, the thyroid
to be appreciated. Significant numbers In order for psychiatric/ hormone is synergistic with estrogen.
of children on the autism spectrum have neurologic disorder to Thyroid and estrogen potentiate each
been diagnosed with PANDAS, Pediatric other. Beyond that, estrogen has an impact
Autoimmune Neuropsychiatric Disorder
be treated nutritionally, on neurotransmitter levels. Estrogen
Associated with Streptococcus. Others the body should synergizes serotonin. So when estrogen
have symptoms that are similar to PANDAS be supported with levels drop during menopause, the activity
but which do not quite fit the stringent of thyroid hormone is diminished, adrenal
diagnostic criteria. PANDAS is caused appropriate levels of gland function is reduced, and serotonergic
by antibodies that the body produces to vitamins, minerals, and activity is lessened. At menopause, the
combat streptococcal infection attacking amino acids. woman’s supply of sex hormones no
the brain. It produces significant behavioral longer comes from the ovary. It comes
symptoms, such as obsessions, compulsions, from the adrenal glands. If the adrenal
and weird stereotyped behavior. To make an indicator of thyroid function. Measurement glands are overtaxed and cannot produce
official diagnosis, group A beta hemolytic of TSH, free T3 and free T4 is somewhat those hormones, the patient experiences
streptococcus needs to be cultured from better, but it is important to have other a significant decline in well-being. For
a site of infection in the child’s body and information also. Reverse T3 is an inactive optimal psychological function, hormones
other diagnostic criteria must be met. In form of thyroid hormone that may prevent should be balanced using bioidentical, as
practice, many children will be found to the active form from functioning. It is opposed to synthetic, hormones, and the
have one or several strains of strep in their important to know its level also, to check underlying adrenal stressors be addressed.
body, particularly in the stool, and will thyroid antibodies and perhaps to examine Antidepressants may help to relieve the
have moderate behaviors characteristic of the gland with ultrasound. The diagnosis symptoms of hormonal decline, but they are
PANDAS. of abnormal thyroid function should not palliation as opposed to treatment.
On June 15, 2004, the Institute of be a casual affair diagnostically speaking; The following bibliography lists books
Medicine issued a report titled, The it requires a minimum of six blood values that are helpful in the further elaboration
Infectious Etiology of Chronic Diseases, in to absolutely make that determination. of these intertwined processes. All of the
which was made the surprising claim that Normalizing thyroid function is critical material quoted earlier from Abram Hoffer
most cases of schizophrenia are caused to feeling well. It must be carried out came from the introduction to Natural
by infections and other environmental thoughtfully and thoroughly. Healing for Schizophrenia and Other
events occurring in genetically susceptible Thyroid and adrenal functions potentiate Common Mental Disorders.
individuals. An association between each other. If adrenal gland function is low,
infection with the HSV2 virus and higher there is strain on the thyroid. If appropriate
rates of this psychotic disorder was noted. thyroid support gives the patient symptoms,
Increased levels of antibodies to Toxoplasma the adrenal gland must be treated first, Bibliography
gondii were found in individuals with recent and the thyroid addressed again later. The Bock, Kenneth, MD, Stauth, Cameron.
onset schizophrenia. To normalize behavior adrenal glands are the body’s first line Healing the New Childhood Epidemics.
in these cases, the infection must be of defense against stress. They produce Ballantine Books. New York. 2001.
eliminated. cortisol, a stress hormone with important Edelman, E. Natural Healing for
In order for psychiatric/neurologic functions. Adrenal stressors include chemical Schizophrenia and Other Common Mental
disorder to be treated nutritionally, the toxins, allergies, infections and psychological Disorders. Borage Books. Eugene, OR,
body should be supported with appropriate stress, among other things. High glycemic 1998.
levels of vitamins, minerals, and amino acids. index foods, foods that increase blood sugar Hoffer, Abram, MD, PhD. Orthomolecular
This varies tremendously from individual levels rapidly and then let them drop, are Medicine for Physicians. Keats, New
to individual. These levels are monitored a stressor to the adrenal glands. Cortisol Caanan, CT, 1987.
through biochemical testing of blood and is the hormone which must be secreted to Hoffer, Abram, MD, PhD. Orthomolecular
urine. Essential fatty acid levels should be prevent that blood sugar drop. Patients Treatment for Schizophrenia. Keats
optimized. In particular, adequate types and with hypoglycemia are not able to produce Publishing. Los Angeles, CA,1999.
quantities of B-12 and folic acid should be enough cortisol quickly enough to keep Larson, Joan Matthews, PhD. Depression-
present. their blood sugar levels steady. Patients Free, Naturally. Ballantine Publishing
Hormone balance is also critical to optimal with postural hypotension, dizziness upon Group, New York, 1999.
psychological function. Thyroid hormone coming to an upright position quickly, are Ross, Julia. The Mood Cure, Penguin
is a central metabolic regulator well known experiencing a blood pressure drop that Group. New York, 2002.
as a cause of depression, anxiety, and indicates that their adrenal function is Vhiet,Elizabeth Lee, MD, Women, Weight
many other symptoms when unbalanced. impaired. Adrenal hormones regulate blood and Hormones, M. Evens and Company,
Measurement of thyroid stimulating pressure also. New York, 2001.
hormone (TSH) alone is a totally inadequate In addition to thyroid and adrenal

30 THE AUTISM FILE | www.autismfile.com REPRINTED WITH PERMISSION © THE AUTISM FILE ISSUE 32 2009