MPhil and PhD Courses for Organic Section Institute of Chemical Sciences, University of Peshawar, Peshawar

Prepared By

Sajid Ali Assistant Professor (IPFP) Institute of Chemical Sciences University of Peshawar, Peshawar, Pakistan 2013

Course title: Chemistry of Glycosides (Cr. 3)

Course contents: Glycosides of flavonoids, coumarins and saponins: isolation, detection and chromatographic separation; acid, alkaline and enzymatic hydrolysis to aglycones, identification of sugar residue; Spectroscopic determination of aglycone and glycoside structures; Derivatization, structural elucidation and biological importance of glycosides.

Recommended books: 1. Naturally Occurring Glycosides, Raphael Ikan, John Wiley & Sons (1999). 2. Introduction to Flavonoids, Bruce A.A. Bohm, Harwood Academic Publishers, Canada (1998). 3. The Flavonoids - Advances in Research since 1986, J.B. Harborn, Chapman & Hall, London (1994). 4. Advances in Plant Glycosides, Chemistry and Biology, C-R. Yang and O. Tanaka, Elsevier (1999).

Course title: Pericyclic Reactions (Cr. 3)

Course contents: Huckel molecular orbital and perturbation molecular orbital theories; Frontier orbitals (HOMO-LUMO) concept; orbital symmetry; alternant and non-alternant hydrocarbons, Huckel and Mobius systems; Classes of pericyclic reactions: electrocyclic, cycloaddition, sigmatropic and chelotropic reactions and their interpretation through (a) orbital symmetry conservation (b) frontier orbital treatment and (c) Huckel-Mobius Approach; Applications to organic synthesis.

Recommended books: 1. Pericyclic Reactions: A Textbook, R. Hoffmann and S. Sankararaman, WileyVCH (2005). 2. Electrocyclic Reactions - from Fundamentals to Research, F. L. Ansari, R. Qureshi and M.L. Qureshi, Wiley - VCH (1999). 3. Orbital Symmetry and Reaction Mechanism, E.A. Halevi Springer-Verlag (1992). 4. Organic Chemistry, J. Clayden, N. Greeves and S. Warren, 2nd Edition, Oxford University Press (2012).

Course title: Advanced Heterocyclic Chemistry (Cr. 3)

Course contents: Chemistry of heterocyclic compounds containing oxygen, nitrogen and sulphur with emphasis on their synthesis, reactions, stereochemistry and spectroscopy; fused ring systems involving furan, pyrrole and thiophene, heterocyclic analogues of quinoline, heterocyclic compounds with more than one heteroatom, heterocyclic compounds with a seven membered ring.

Recommended books: 1. Heteroatom Chemistry, E. Block, Verlagsgesellschaft, Germany (1989). 2. Aromatic Heterocyclic Chemistry, David T. Davies, Oxford Science Publications, England (1991). 3. An Introduction to the Chemistry Of Heterocyclic Compounds 3rd Ed., R. M. Acheson, John Wiley and Sons, New York (1976). 4. Heterocyclic Chemistry, R. K. Bansal, Wiley Eastern Ltd., New Delhi.

Course title: Chemistry of Organometallic Compounds (Cr. 3)

Course contents: Introduction, nature of bonding, and complexes; Preparation of organometallic compounds; Application of organometallic compounds in organic chemistry for hydrogenation, isomerization, hydrosilylation, polymerization, hydroformylation, cyclisation, carboxylation, carbonylation, olefin metathesis and hydrocyanation.

Recommended books: 1. An Introduction to Organometallic Chemistry, A. W. Parkins & R. C. Poller, McMillan Education Ltd., New York (1987). 2. Principles of Organometallic Chemistry, P. Powell, Chapman & Hall, New York (1988). 3. Organometallics: A Concise Introduction, C. Elschenbroich, 3rd Edition, Wiley-VCH (2006). 4. Organometallic Chemistry and Catalysis, D. Astruc, Springer (2007).