Tablets With Fillers

Fillers are added to pharmaceuticals drugs and nutraceuticals supplements to help with the manufacturing and stabilization of these products. They are the glue which bind and stabilize a supplement. Historically they have been considered inert and without any medicinal benefit however they do influence the benefits of the intended ingredients. These fillers can affect the absorption rate and benefit of the rate by as much as 65%. This assumption has allowed their use to be wide-spread with little regard for their actual influence. Fillers, for example have been found to initiate or participate in chemical and physical interactions which can compromise the efficacy of a medication or supplement. Fillers can influence the efficacy and quality of supplement and drugs and are best avoided when choosing health and vitamin supplements. The major concern with the use of some fillers in nutraceuticals and pharmaceuticals is their ability to interact to the medicinal ingredients, hence influence the reliability of products. With chemical and physical interactions occurring within a supplement it is difficult to determine the exact efficacy of the product remaining. Interactions can render the active ingredient less active and make it less bio-available (less available for the body to use). Limited research to determine the impact of long-term use of fillers on health. Pharmaceutical companies are also not required to list the exact amount of fillers within the supplement; therefore it is difficult to determine the amount of non-medicinal ingredients versus medicinal ingredients. Below are some listed fillers having adverse health effect: Magnesium stearate: Is a widely used filler in nutraceutical and pharmaceutical products. Some studies have shown that it suppresses immune function. The absorbability of products is also questionable when magnesium stearate has been added to a formula. As a powerful binder of active constituents the rate of dissolution of a substance is altered, yet studies have shown that bioavailability remains the same. Some manufacturers believe that this is true and will only use magnesium stearate in the formulas as filler and never as coating due to the question of dissolution. Titanium dioxide: Is a common whitening agent used in some supplements and pharmaceutical agents. It has shown to be a potential carcinogen to humans. Rats studies have shown that inhalation of ultrafine titanium dioxide can cause respiratory tract cancer. Silica: Is an abundant mineral in the earths crust. Is found in nature as sand or quartz and is a flowing agent used in supplements. When inhaled it has been shown to cause auto-immune dysfunction. Inhalation has also been shown to cause lung cancer. Parabens: Are a group of widely used preservative and anti-microbial agent in personal care products and supplements. There is growing concern that parabens can cause hormone disruptions and they have been found in high concentrations in breast cancer tumours. Parabens can be found in supplements as methylparabens, ethylparaben, propylparaben, butylparaben. Lactose: A sugar found in milk can cause severe gastro-intestinal upset in individuals sensitive to milk products. Maldodextrin: Is a polysaccharide that is rapidly converted to glucose in the blood stream. Maltodextrin can come from a variety of startch products. Wheat and corn are the most common. Although not generally a concern in supplements, the source of maltodextrin should be noted. If from a wheat source, gluten will be removed, but should still be avoided in individuals with celiac disease to avoid any potential adverse reaction. MSG: or Monosodium glutamate is a common flavouring agent in supplements. It is a known neurotoxic agent and should be strictly avoided when choosing supplements. It has also been shown to cross the placenta and induce neuronal damage in developing mice.MSG is a food

shown to cross the placenta and induce neuronal damage in developing mice.MSG is a food additive used to enhance the flavour of food. Reactions to MSG may occur and may include: tingling and weakness around the face, temple, upper back, neck, and arms, with flushing of the skin and warmth. Some people experience heart palpitations, intense thirst, anxiety, nausea, and vomiting. Talc: Is a known carcinogenic. Studies have shown that it increases the risk of endometrial cancer in peri-menopausal women when used topically in the peri-anal area. Inhalant or intravenous talc exposure increases the risk of pulmonary toxicity. Intravenous talc can lead to various degrees of granulomatous formation, compromised pulmonary function or death. The use of talc should be strictly avoided in supplements, oral, inhaled and topical. Microcrystalline cellulose: Is a bulking agent used in supplements to fill capsules when the medicinal agents are too small. It is ideal filler as it is naturally occurring and derived primarily from wood pulp. It is glucose units bound together by a beta 1-4 linkage which creates cellulose a fibre indigestible to humans. It enters and leaves the digestive tract unchanged and is chemically inert. Gelatin: Is derived from collagen in animals skin and bones. It is a gelling agent used in supplements to help coat the outside of capsules to make them easier to swallow. Gelatin is commonly found in various desserts and gummy candies. A vegan alternative to a gelatin capsule is hypromellose. Gellan gum: Is commonly used as a food additive, it is used in most soy drinks to help keep soy products in suspension. It is used as a thickener and stabilizer in supplements. A study examined the dietary effects of large quantities of gellan gum and found that it seemed to affect transit time by either increasing or decreasing time in a few subjects. Serum cholesterol levels were decreased by an average of 12% in males and 13% in females. No adverse physiological effects were seen in the subjects. Tartrazine: A yellow colouring agent used in some supplements and pharmaceuticals has been shown to cause adverse reactions in certain individuals. It is well known to cause asthma and urticaria in sensitive individuals and has been shown to cause behavioral changes such as irritability, restlessness, and sleep disturbance in children. The use of any food colouring additive should be strictly avoided when choosing supplements. Allura Red: A red colouring agent used as a food additive has been linked to both behavioural and physical toxicity. When fed to rats in animal studies, rats displayed significantly reduced reproductive success, weight, brain weight, survival and impaired female vaginal patency development. Behaviourally, the rats had significantly decreased running wheel activity when compared to control. Indigotine: A blue food colouring agent has been linked to asthma in one study. A case report outlined increased cough, dyspnea, wheezing and nasal congestion in a subject immediately following exposure to indigotine at work. Vita4Life! wants you to be informed with a clear and detailed understanding of the different ways of consuming supplements and how they can affect your health. The man-made fillers used to make products palatable can harm your system and create an unnecessary absorption roadblock. Thats why we offer you encapsulated vitamins and bariatric supplements with no fillers or additives. There are no common allergens, binders, artificial colors or flavors in our bariatric vitamins. They are lactose free and contain no wheat or gluten. For the best possible return to your body our multivitamins dissolve within minutes. -Vita4life Inc.