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Page numbers correspond to FA 2009 edition 1. tRNA structure pic-what part binds to amino acid- 3 end 2.

Picture of man with rash onl on one side of abdomen !so thin" shingles#- VZV $. %urnt sugar urine- isoleucine &. 'mmediate transplant re(ection due to what) * antibodies +. Pic of CMV ,. -n. me "inetics graph !/elocit /s substrate#0 as"s which line has same 1 but higher substrate affinit 2. 3raph that has /elocit /s load for muscle contraction and as" what point is isometric- I put E which was closest to the 4-a4is !meaning had the lowest /alue# 5. 6ecreased A789 and high cortisol on low and high-adrenal hyperplasia 9. 3u got hit with a baseball bat on the arm and has problems with superior and inferior subscapular muscles so where is damage) Subscapularis (medially rotates arm at shoulder and adducts it) 10. :now definition of genomic imprinting- differences in phenotype depends on maternal or paternal ene mutation 11. As"s wh does mutation get worse with each generation !so thin" anticipation# ! increase number of trinucleotide repeats 12. ;uestion tal"ing about mononucleiosis and lab showed positi/e heterophil *so "now its E"V and not 7<1 1$. =hat stud has 2 groups of people both with disease but tests effect of new drug) * controlled trial 1&. >traightforward relati/e ris" ?uestion- !20@!20A50##@ !+@!+A9+## B # 1+. :now that A6-: are the fat soluble /itamins and ou will get 2 ?uestions right 1,. Another ?uestion related to A6-: was about their absorption-' thin" answer was trypsin 12. =hat does strepto"inase@tPa act on- plasmino en 15. 9a/e decrease in glucose and carnitine so what is deficienc ) $atty acid transport 19. 6rug o/erdose or withdrawal that causes pinpoint pupils and no reaction e4cept to se/ere pain) %eroin o&erdose !&25# 20. 7ells in lungs with blac" debris) 'ulmonary macropha es !&2&-macrophages clear debris#

21. 6rug or bug that causes increase of cilia in lungs so what cell t pe ( Columnar !&2&pseudostratified ciliated columnar# 22. =hat drug increases neutrophils in chemotherap patients) )ranulocyte-Colony Stimulatin Factor!3-7>F0 202# 2$. 2& ear old with brain lesion on temporal lobe!pic os brain <R'# what organism) 9erpes !might also ha/e been to4oplasmosis so if ou see ring enhancing lesion on pic then pic" to4oC other choices were cr ptoC n meningitisC but ' pic"ed herpes becauses it is a cause for meningitis in people ages ,-,0 (ust li"e n. meningitis but ' "noe herpes affects specificall the temporal lobe# 2&. 12 marines ate meat and canned food from local farm and all got sic"C what is method of action of organism causing sic"ness) >o thin" botulinum to4in-presynaptic *C% !1&1-bloc"s release of A79# 2+. 'nc P8 and inc P88) >o thin" /itamin " deficienc !2C2C9C10# * factor +, deficenc !$$,# 2,. Dad diagnosed with Al.iehmers & months ago and is as"ing ad/ice how to handle things at home- I put to ta-e notes for memory since she is in early sta e and is still capable of ta-in care of herself 22. Pic of negati/e biferingence- out 25. =hat happens to tRNA after it transfers its amino acid to ribosomal tRNA) .etaches !50# 29. =hat /irus is not destro ed b autocla/ing) Creut/feldt-0a-ob disease !prionsC 12$# $0. :id has c stic fibrosis and has fatt stoolsC what organ problem) 'ancreas $1. Person with 3-R6 but antacids stopped wor"ing and has s?uamous cell infiltrated with macrophages( "arrets esopha us !' was also thin"ing it might be s?uamous cell carc# $2. 8here was another ?uestion and answer was adenocarcinoma $$. 9ow do neutrophils get to affected tissue( Increase in endothelial adhesion $&. =hat acti/ates or recruits neutrophils( I1-2 !199# $+. Narcoleps sleep stud C "id falls asleep into which sleep stage) 3EM $,. Person with auditor hallucinationsC delusionsC dishe/eled appearance) Schi/ophrenia $2. 3u that is *nti-social disre ard for and &iolation of ri hts of others4 criminality (called Conduct .isorder if 5+2yrs) $5. :id with bone problemsC blue scleraC bow leggedC father and sister ha/e same) *osteogenesis imperfect-so decrease in colla en type I $9. 8al"ing to 19 ear old about ?uitting smo"ing what else would ou tal" to him about) Seatbelt

&0. Entreated sleep apnea could cause what) *hypertension (associated 6ith obesity4 loud snorin 4 systemic7pulmonary hypertension4 arrhythmias4 and possibly sudden death)8 indi&iduals become chronically tired9 &1. Par/o b19 /irus causes anemia wh ) 7hoice AC something about immune responseC some people put something about infected cells cannot replenish er throc tes arrest of erythropoiesis due to "+:;;; causes erythema infectiosum (<th disease)- =slapped chee-> rash on face and later o&er body8 aplastic crisis in sic-le cell disease8 3"C destruction in fetus leads to hydrops fetalis and death &2. 9ow does NA69 enter mitochondria) Malate &$. 8h roglossal c st arises from what emb onical remnant) Caecum foramen &&. ;uestion about umbilicus and intestines !' thin" about mec"els di/erticulum# and as"s what part of intestine is in/ol/ed( Ileum !$1&# &+. =hat sugar re?uires Na@:-A8Pase for absorption in infants) )lucose !transported b Na@glucose cotransport which is dependant on action of Na@:-A8Pase# &,. 3u with different o2 le/els in heart chambers RAF 1.+C PAF 1.2C DAF 2C >17F 1.+ * VS. &2. 3' hormone that decreases acid secretion and increase 97G$- secretin !$0+# &5. Person with femur cartilage probs and femur head was flatC so how will cartilage sta ali/e or somthin) Dateral femoral arter !for blood since the medial one is damaged because it comes out of the head of the femurC some people thought it had to do something about s no/ial fluid# &9. =hat form of energ can the brain ma"e on its own) :etones so * *cetoacetate and "hydro?ybutyrate +0. %lood cells in urine but no R%7 so what is problem) +1. Person with splenectom - S9 pneumonia !its capsulated# +2. 8he hormone that stimulates cortisol production originates from ! anterior pituitary +$. 'mmunoflourecnt graph that has 76& on a4is and 76$ on 4 a4is and as" what part of graph would represent N: cells-it would be the bottom left because N: donHt ha/e 76$ or 76& !199# ha&e C.+@ and C.<@ +&. =hat mediates repolari.ation in /entricular contraction - A ++. =hat cause depolari.ation in >A node- Ca +,. Patient with s mptoms of portal h pertension li"e periumbilical caput medusa etcC what is it caused b ) * ' put systemic to portal shuntC might also be occluded hepatic /eins ' 3,B and 3C#- this shunt reli&es portal hypertension;;; So D3EF);

+2. >ide effect of nitrogl cerin) "radycardia +5. 'ncrease P89 and 7a and decrease PG& /ia what) +-C< (E%)C +9. Glder man was niceC then changed personalit to uninhibited * 'ic-s disease * frontal lobe ,0. Pic of A6P:6 of mother who died and as"ed what percent of children are li"el to get this disease) *' put <,G !A6# ,1. =ar /eteran wa"es up at night and screams and goes bac" to sleep and doesnHt remember an thing) *ni ht terror !' put ptsd but ' thin" its wrong because in ptsd the ha/e night mares that ' thin" the remember# ,2. 8>9 recepot mutation that allows 8>9 to bind but pre/ents action where is mutation) *remember that 8>9 2nd messenger is cA<P ,$. Fetus with normal si.e but decrease amniotic fluid) 3enal a enesis ,&. %leeding in the $rd trimester) ' forgot the choices but if its painful then abruptio placentae and if painless than placenta pre/ia !&,$# ,+. 3enetic tree with affected moms passing it on to some daughters but affected sons do not li/e and onl unaffected sons sur/i/e- H-lin-ed dominant ,,. =hat hormone tells if a woman is o/ulating) 'ro esterone starts to increase C# hrs before o&ulation (so the body temp also starts to rise then) ,2. 6uring h sterectom there is a ris" of ligating what structure) Ireters ,5. <esonephric stimulates uteric bud which gi/es rise to what) Collectin tubules Ireteric bud- i&es rise to ureter4 pel&ises4 calyces and collectin ducts ,9. =hat organism causes flas" shaped ulcer) *moebic colitis 20. -%1 causes cancer where) Fasopharyn eal 21. -rror t pe ?uestions with t pe ' error!a#B.0+ and t pe '' error!%#B.2 and as"s for power) 2,G !,&0 powerB1-% # 22. >tandard de/iation ?uestionF there is a graph that has 2 lines and it is as"ing about the group of people in the bottom line whose test results were from &0 to somthin !this was 1 standard de/iation# and the national a/erage was &0 and it as"ed how man people in that group performed below national a/erage-so basicall the line on the graph represents 1 >6 which is $&I meaning that 1,I are below national a/erage-answer was li"e +,-C, 2$. Picture of neuro (unction and as" where clonidine acts) *C receptors 2&. 3anciclo/ir <GA) Jhymidine -inase

2+. Famciclo/ir <GA) Jhymidine -inase 2,. -ffects of A7- inhibitor on reninC angiotensinC aldosterone ( Increase4 increase4 decrease !&+2# 22. 6efect in what part of complement allows Niessieria bacteremia- end complement!200C 7+-75# 25. =hat complement is responsible for acti/ating mast cells- C3a!200C anaph la4is# B:9 $irst Kuestion on the e?amL ##yo 6oman 67 hematuria4 and left renal mass in abdomen4 increased erythropoietic mass4 and increased erythropoietin concentration4 6hat is the cause of erythropoiesis- 'araneoplastic 50. 3u with u/ula de/iated and paral .ed trape.ius and >7< !basicall 7N 10 and 11#C where is lesion) *0u ular foramen 51. 7artoon pic of lung di/ided into $ parts!li"e on page &51# and as"s to list in order of part that recei/es most blood to part that recei/es least blood) IIIMIIMI 52. Person in high altitude for $ da sC what change would ou see in heart) Pulmonar /asoconstriction causes R19 but R19 wasnHt choice so- pulmonary artery 5$. 3raph - >pecificit / >ensiti/it * which point rules cancer 'N * point *- lo6est specificity !graph is 1-specificit # * specificit rules 'N so want low /alue on graph 5&. 3raph showing drug efficacies and potencies * which one is the most potent and has full efficac * * 6ith hi hest pea- and furthest to the left 5+. 6rug that eliminates bicarbonate ! ' thin" gu had 79F and pulmonar >4# ! aceta/olamide 5,. <other as"s for 19 ear old sonHs medical report * dont i&e it to her 6ithout sons permission 52. =oman is a smo"er and wonHt ?uit. 9ealth is bad. =hat do ou tell her) 8hin" answer is ! if your breathin continues to 6orsen4 6hat treatment 6ould you li-e( 55. =hat is the effect of increased insulin) * ' put decreased sodium ((((7 !' donHt remember the choices e4actl but (ust remember that insulin inc Na retention in "idne s and inc : in cellsB 8RE- pg112# 59. ;uestion of woman who sa s her husband thin"s she is spending too much time in the hospital with her premature infant - * brin him in and lets discuss 90. =oman is in(ured but must go home because her husband will get mad at her --- Im concerned ! tell me about your home life9 91. 8oo much 8>9C etc. secreted - bitemporal heminopsia * pituitary tumor 92. =oman with lesions onl on front part of bod on abdomen and legs that are e/enl spaced linesthis one dro/e me cra. and ' put some path disorder but ' thin" it is (ust factitious disorder 9$. <an has problems with mo/ementC and mental deficienc * 9untingtons 7 caudate nucleus 9&. Picture of intracellular bean shaped organism so what culture do ou use to grow it * Jhayermartin !niesseria# 9+. Deft descending coronar arter occlusion * ischemia of the anterior &entricular septum 9,. <acroc tic !102 u# h pochromic anemia ! hyperse mented neutrophils !b12 def# 92. Pic of cells with auer rods- *M1 95. Pic of stuff inside lungs !asbestos# increases ris" of what) * broncho enic carcinoma

99. =hat causes lung e4udate in pleural effusion) - increased &ascular permeability 100. =hat cell is dominant in marrow in agranuloc tosis@aplastic anemia ! adipocytes really((((((((( 101. ;uestion sa in that 'g< "appa!1C$# 'g< "appa!1# ) ' put I ) -appa (+) 102. 9 dronephrosis * nephrostem tubesC what do ou see in the ne4t 2& hours ( Increased urine4 increased urine potassium 10$. 6rug is (ust prolonging disease !people li/ing longer with d.# * pre&alence increases4 incidence stays the same (@C) 10&. =hat is the ligand for 77R+ receptor ! chemo-ine 10+. 7alculate lung compliance which B change in 1@change in P where pressure e?uals intrapleural pressure before inspiration minus intrapleural pressure after inspiration * so ' thin" it was 1@!1++# N ,9+17cm%CE 10,. %lue fingerC high platelets * essential thrombocythemia 102. 9usband is dead upon arri/alC child and friends present - Ja-e 6ife into pri&ate room and inform husband is dead on arri&al 105. Doss of memor * parietal lobe 109. 7ortical atroph of the "idne * pro?imal con&oluted tubule is effected 110. Dad with problem with thumb and wrist in/ol/ment *.e Ouer&ain s ndrome 111. =h does barium not enter intestine * possibilities * 1# membrane is impermeable to barium or 2# pumped bac" out after absorptionC ' put it goes mo/es through intestines too fast or something but no idea 112. =hat hormone increases after menopause) $S% 11$. ;uestion about what blot do ou use to detect 6NA) Forthern !snow drop# EA the Kuestions to follo6 are Kuestions I dont remember the &i nette completely or that im Pus not sure of the ans6er99enPoy 11&. Patient coughing up blood so what t pe of pericarditis does he ha/e) ' put hemorrha ic 11+. >omething about patient gi/en an A7- inhibitor but renal actici/t is delated after A7inhibitor so what is problem) ' thin" ' put somthin about renal cell damage or carcinoma or somthin 11,. ;uestion as"ing what e4plains the effects of 9ib /accine or somthin * if ou "now that bab gets 9ib /accine right after the are born ou should be able to get the right answerC ' remember one of the answers being somthin about gi/ing mothers 9ib /accine while pregnant but that not true 112. <GA of glipi.ide !insulin drug# but ' forgot what the choices are so go o/er it !292#

2nd gen sulfon lureaF close :A channel in beta cell membC so cell depol inc 7a2A influ4 triggering of insulin release0 to4F h pogl cemia 115. =hat increases the ris" of 3' cancer- I put increase number in polyps!$1, under colonic pol ps it sa s the more /illous pol ps the more li"el it is to be malignant so ' thin" thatHs right# 119. ;uestion about what stimulates the release of prostaglandins and leu"otrienes on state of h po4ia) ' put lo6 EC le&els but no idea 120. =hat is needed to "ill staph aureus but it wasnHt as"ing about drugs it was as"ing about immune response li"e macrophagesC neutrophils etc 121. :id that is not tolerant to aspirin but too" 2 pills and had some >4 and as"s what causes these >4) Re eHs s ndrome in children with /iral infections0 irre/ binds 7GJ which dec s n of both thrombo4ane and prostaglandins. 122. 3irl was born without /aginaC uterusC or o/aries!or ' thin" o/aries were strea"ed or somthin#-' put mom too- andro ens durin pre nancy but not sure >trea" o/ar in 8urnerHs !&+ JG# 12$. :id got bit b an animal and ta"en to doc what do ou gi/e him !basicall for rabies#) ' put -illed &accine plus riba&arin but other choiced were onl "illed /accineC li/e /accine etc so not sure 12&. Person had recurrent s p ogenes infection but had normal immuni.ations and reco/ered fine from chic"en po4 or 1K1C so what cell defect do the ha/e) <acrophages etc))) 125. ;uestion about a drug that acts on rate-limiting step of catelcholamine s nthesis and as"ed what is that step) ' thin- tyrosine dopa but chec" it 102- t rosine h dro4 lase 12,. 3u with sudden blindness in 1 e eC can be caused b what) 7hoices were li"e tumor bloc"ing optic tractC something about /isual corte4C 2 choices with arteriesC ' thin" it should be 1 of the arter choicesC some people put occipital ischemia in contralateral lobe 122. Alcoholic with ' thin" neuro probs what /it def) "+C !' donHt rmr %1 being a choice# 125. =hat is responsible for mottled spot appearance on ischemic organ) Maybe I1+ and JF$ 129. First thing that happens in ischemia( Endoplasma 3eticulum swelling))) 1$0. Dad whose husband recentl died and is sad and is tr ing to flirt with the doctor) ' put ideali/ation because the other choices didnHt ma"e sense !=i"ipedia sa sF n ps cholog C ideali.ation refers
to a defence mechanism in which a person who percei/es another to be better !or ha/e more desirable attributes# than would actuall be supported b the e/idence# so ' donHt "now

1$1. 8here was a ?uestion where the choices were pics of different /isual fields of e es !page &01# and something about endocrine so ' thin" answer was bitemporal hemianopia !this could be the same ?uestion as number 90 abo/e# 1$2. ;uestion about 6NA g rase drug !page 15&#-' thin" answer was ciproflo?acine

1$$. 9ow does scopolamine decrease affects of anti-h pertensi/e drug !' thin" it was atenolol# 1$&. 3u got his b baseball bat on side of arm and it affected superior and inferior subscapularis muscles so where is lesion) 7hoices were 1st ribC 2nd ribC something triangleC something notch 1$+. 1aginal infection after ta"ing antibiotics-should be candidia but forgot if its there !1+,# 1$,. >"in growth pic on hand or ma be on face with raised edges- ' put basal cellC other choices were s?uamousC /erruca /ulgaris 1$2. 'tch /agina with ellow discharge- ' put candida because it causes itch and has white chees dischargeC a lot of people put trachamonas because its itch but that has greenish discharge and its motile so it causes froth discharge but ' donHt remember if it said froth C and n. gonorrhea has cream purulent discharge but ' dno about itch ness 1$5. >ome weird pic of an organ that some people said was the cerebellum and it was pointing to ner/e endings and another organ or somthin-it loo"ed li"e the free ner/e endings so ' pic"ed pain !page $2+C the arrow was pointing to something that loo"ed (ust li"e the free ner/e ending pic on that page#C other choiced were 2 pt proprioC touchC etc 1$9. 3u had scar 10 da s old and came to ta" out sutures and it was h peremic so this is due to what( I1-C ma be 1&0C 1&1. 8here were 2 ?uestions that had to do with spinothalmic tract-for one of them it as"ed something about /ibration in legs and the answer was spinothalmic and the other one the answer was le 1&2. >omething about cer/ical adre4nal mass) ' put cystadenocarcinomaC other choices were dermoid c st !see o/arian cancers# 1&$. >omething about person with recurrent duodenal and gastric ulcers and also had a mass on head of pancreas so what is problem) ' put 9. p lori but other people said something else to do with pancreasC other choices were inc pancreatic en. mesC increased secretion from acinar cellsC increased secretion from islets 1&&. what lobe is responsible for an4iet and mood prob) 9a/e to pic" lobe on a pic 1&+. what does aspirin increase) ' thin" its leu-otrienes 1&,. ' put Crohns as an answerC ' thin" it said there were patches of something so ' thought of s"ip lesions 1&2. ' thin" ' had F$-+ as an answer but cant remember ?uestion 1&5. >ome bone problem at hip with moth something appearance) <a be its tal"ing about osteopetrosis !marble bone disease# 1&9. ;uestion as"ing about how microtubules contract and ou had to pic a graph that was length /s time) A# b# c# d# ' pic-ed C

Jhese are Kuestions from another file for the same comp but I Pus dont remember the Kuestion so I 6ill Pus copy and past them 1+0. =hat drug decreases /ascular resistance as well as salt retention) * A7- inhibitor * Disonopril 1+1. ;uestion with answer LfibroticM 1+2. %o canHt concentrateC is tiredC one answer is lead poisoning !most chose lead poisoning# 1+$. <an is ta"ing four medications for h pertensionC has diarrheaC brown urineC muscle wea"ness * what caused this) gemfibrosil 1+&. Din"age anal sis * anal .e chromosomes of the proband 1++. 7hart with increased glucose on top row with drug J and decreased on the bottom row with drug J. drug J is a partial agonist 1+,. 9eart ?uestion * fatigueC weight lossC left /ent h pertroph * m 4oma))) !' remember this ?uestion but didnHt pic m 4oma# 1+2. =hat could decrease the patientHs s mptoms of weight loss * either digesti/e en. mes or glucagon 1+5. Puralent secretion * what cell is deficient) * neutrophils))) 1+9. 7 closporine action )) binds to c cloph lins * bloc"s 8-cell differentiation and acti/ation b inhibiting calcineurin * pre/ents production of 'D-2 1,0. Fibrosol is one answer 1,1. Angiotensin '' increases resistance in the efferent /essel)) 1,2. Dipid A is the antigen for gram negati/e 1,$. 7$ is on 8-cellsC 76$ /s 'g< - J-lin"ed agammuglobulinemia 1,&. Noung "id (ust got o/er a sore throat * streptol sin G mechanism 1,+. 1illi loo"ing cells * the sa this is urothelial carcinoma !the thin" this is transitional carcinoma# 1,,. Anterior pituitar * basophils L%-flatM * %asophil * F>9C D9 1,2. Alcohol withdrawl * delirium tremensC hospital for car accident 1,5. >nrps * ta"e out introns 1,9. Normal e4cept for high ->R * s stemic inflammator response 120. Dow platelets - soft tissue hematomas !consider petichiae# 121. Dad with Pagets disease * osteosarcoma 122. %one with sclerotic areas * osteom elitis 12$. Pentose phosphate shunt in R%7 is for what) -ither NA6P9 or glutathione reduction 12&. Doo" up the 'g3 deficienc diseases 12+. Patient has high 8&C 8$C but low 8>9 * what was the ?uestion 12,. 3 mnast who hadnHt had periods - ris") * endometrial cancer)) 122. 'sot pe * what is responsible) 2-$-& on immunoglobulin !' remember this one it was a pic of an immunoglobulin and as" what parts of it change for isot pe switching# 125. 78 scan * which is the s mpathetic trun" !?uestion ma ha/e been on 9ornerHs# * the arrow closest to the spinal cord

129. 1+I of blood /ol. lostC what does the bod do immediatel to compensate for lossO' forgot the answer choicesC but this is class ' hemorrhage and so thereHs no change in /ital signs and fluid resuscitation isnHt necessar C so ' guess answers does nothing. 150. >omething about a gene getting confused and repairing the newl s nthesi.ed chainOwhat is this called) Recombinational repairC other choices base-e4cision repairC mismatch repairC photoinduced repairC nucleotide-e4cision repair 151. $, o woman for the past , months ammonorrheaC wh ) prolactinemia 152. newbornC increased 8>9C decreased 8&C bab is at ris" for or hasO)) <ental retardation 183. =hat is the mechanism of gentamicin resistance beta lactamase was one asnswer !gentamicin resistance--could be e4plained b the spontaneous transfer of a plasmid or plasmids# 15&. De/oflo4acin mode of action-- broad-spectrum antibiotic that is acti/e against both 3rampositi/e and 3ram-negati/e bacteria. 't functions b inhibiting 6NA g raseC a t pe '' topoisomeraseC and topoisomerase i/P&&QC which is an en. me necessar to separate replicated 6NAC thereb inhibiting cell di/ision 185. 6escribed angiod splasia but did not sa it was angiod splasia of ascending colonC what is complicationhemorrhage
15,. . AN> was decreased aldosteroneC decreased reninC decreased angiotensis....?uestion was about 98N pt with h po"alemic al"alosis 152. 7 tos"eleton... ?uestion about what organelle in/ol/ed iwth d nam stabilit .. has monomer and pol mer organi.ation ! ' also put c tos"eleton#

155. A +$ ear old woman wants to ha/e se4 with her husband but it hurts. >he has irregular menarche. =h is she ha/ing this problem) 159. A patient has had recent surger and he is now ha/ing s mptoms of seeing aliens and e/en points one out to ou when ou come in. AnswerF %rief ps chotic disorder 190. A patient has a round face. =here is the problem) AnswerF Kona fasiculata 191. 8he fre?uenc of the A allele)!%ased on AA B +0C A3 B 50C 33 B 20# AnswerF 1&0@&00 192. A girl presents with recurrent E8' AnswerF 6iabetes 19$. A man has a m ocardial infarction. Aspirin is the acute thrombol tic agent gi/en. =hat does it affect) AnswerF thrombo4ane

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