Code: 9A23502

1
BIOCHEMICAL REACTION ENGINEERING - I
(Biotechnology)

B.Tech III Year I Semester (R09) Regular & Supplementary Examinations December/January 2013/14

Time: 3 hours Answer any FIVE questions All questions carry equal marks
***** 1 (i) (ii) (iii) (iv) 2 Explain the following: Molecularity. Order of the reaction. Rate of reaction. Rate constant.

Max. Marks: 70

Decomposition of A by second order kinetic shows 50 % conversion in 5 min, how much longer it will take to reach 75 % conversion in a batch reactor? Derive the performance equation for plug flow reactor with the graphical representation. Describe in detail the following Batch reaction system. Fed-Batch reaction system. Derive the kinetic equation for un-competitive inhibition process. Discuss the role of thermodynamic parameters in the calculation rate of biological reaction. Derive the energy balance equation for CSTR under non isothermal condition. Explain briefly the reasons of non ideality with the help of simple diagrams.

3 4 (a) (b) 5 6

7 8

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Code: 9A23502

2
BIOCHEMICAL REACTION ENGINEERING - I
(Biotechnology)

B.Tech III Year I Semester (R09) Regular & Supplementary Examinations December/January 2013/14

Time: 3 hours Answer any FIVE questions All questions carry equal marks
***** 1 Show that the formation of expression .

Max. Marks: 70

can be expressed by the predicted rate

In a batch reactor 80% reactant is converted in 8 min, 90% is converted in 18 min. Find a rate equation to represent the reaction .

3 4

Derive the performance equation for batch reactor with the graphical representation. Derive the line weaver Burk plot and Eadie-Hofstee plot expression from Monod equation. Derive the kinetic expression for competitive inhibitor system. Explain the following Yield. Selectivity. Conversion. Derive the energy balance equation for batch reactor under non-isothermal condition. With the neat sketch, explain in detail the C and F curves.

5 6 (a) (b) (c) 7 8

*****

Code: 9A23502

3
BIOCHEMICAL REACTION ENGINEERING - I
(Biotechnology)

B.Tech III Year I Semester (R09) Regular & Supplementary Examinations December/January 2013/14

Time: 3 hours Answer any FIVE questions All questions carry equal marks
***** 1

Max. Marks: 70

Discuss the elementary and non elementary reactions and explain briefly the kinetic models for non-elementary reaction. Decomposition of A by first order kinetic shows 50 % conversion in 5 min, how much longer it will take to reach 75% conversion in a batch reactor. A homogeneous liquid phase reaction takes place with 50 % conversion in a mixed reactor. What will be the conversion if this reactor is replaced by one 6 times as larger all else remaining unchanged? Explain the sterilization kinetics with appropriate equations. Explain the following Competitive inhibition Un-competitive inhibition and Non-competitive inhibition. Discuss in detail about multiple reactions with its kinetic expressions. Derive the energy balance equation for plug flow reactor under non-isothermal condition. Discuss in detail the method of diagnosing the ills of non-ideal reactors.

4 5 (a) (b) (c) 6 7 8

*****

Code: 9A23502

4
BIOCHEMICAL REACTION ENGINEERING - I
(Biotechnology)

B.Tech III Year I Semester (R09) Regular & Supplementary Examinations December/January 2013/14

Time: 3 hours Answer any FIVE questions All questions carry equal marks
***** 1

Max. Marks: 70

Determine the activation energy and frequency factor using Arhenius theory from the following data 0.001 0.050 0 T( C) 0 100 Derive the Uni-molecular type first order rate expression for the constant volume system using integral method of data analysis. Derive the performance equation for mixed flow reaction and also show the graphical representation. Derive the Monod equation and mention its application. Derive the kinetic equation for non-competitive inhibition process. Derive the kinetic expression for the irrepressible reactions in parallel system using integral method of data analysis. Discuss in detail the design of homogeneous reactors in adiabatic condition with appropriate equations. Discuss in detail the models available for the study of non-ideality.

4 5 6

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