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Human Digestive System composes of human alimentary canal and associated organs
Human Alimentary canal (also called the gut) is a long muscular tube which starts from
mouth , followed by the oesophagus, stomach, small intestine, large intestine and
ends with the anus.
The associated organs that help in digestion are the pancreas, gall bladder and liver.
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• Serosa
Physical digestion is the process by which food is broken down into smaller pieces so
as to have a large surface area for enzyme action.
Chemical digestion is the process by which large food molecules are broken down
with the help of digestive enzymes to soluble, smaller substances that can be
transported into the blood through the intestinal walls.
• Assimilation is the process where the absorbed food materials are converted to new
protoplasm or utilized by the body.
• Egestion is the removal of undigested matter (faeces) through the anus.
Peristalsis
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Parts of Alimentary Canal and its functions
Mouth
• Takes in food. (INGESTION)
• has teeth to cut food into smaller pieces. (PHYSICAL DIGESTION)
• has tongue to roll the food into spherical masses (boli)
• Has salivary glands that produce saliva which contains an enzyme (salivary
amylase) to digest starch to maltose. (CHEMICAL DIGESTION)
Salivary amylase
Starch Maltose
Note: The salivary amylase works best in neutral pH. Hence the pH in the mouth is
neutral (pH 7).
Oesophagus
Stomach
• A muscular bag with sphincters (rings of muscles) at its entrance and exit to open
and close
• Has gastric glands which that secrete gastric juice (water, mucus, hydrochloric
acid and enzymes)
Roles of HCl:
1. Stops the action of salivary amylase
2. Kills harmful germs, parasites and bacteria
3. Changes the inactive form of protease to active forms in stomach
4. Provide an optimum pH for the protease (pepsin) to work in
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The acid changes/denatures the inactive enzymes to active enzymes.
HCl
Pepsinogen Pepsin
HCl
Prorenin Renin
pepsin
Proteins Polypeptides
Renin is an enzyme that is unique to mammals since only the young of mammals
depend on their mother’s milk for food.
Renin curdles the milk proteins, allowing the milk proteins to stay long enough
for the stomach to be digested.
renin
Soluble milk proteins Insoluble milk proteins
(caseinogen) (casein)
pepsin
polypeptides
• The muscles in the stomach walls is churned and mixed the food into a semi-
liquid state called chyme.
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Structure of Stomach
Duodenum
• U-shaped tube which receives bile and pancreatic juice containing enzymes to digest
food. Both fluids are alkaline.
• Has glands in intestinal walls to secrete intestinal juice. This liquid is alkaline and
contains enzymes to digest food.
Trysinogen Trypsin
Intestinal enterokinase
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Proteins Polypeptides
Intestinal maltase
Maltose Glucose
Intestinal lactase
Lactose Glucose + Galactose
Intestinal sucrase
Sucrose Glucose + Fructose
Intestinal erepsin
Polypeptides Amino acids
Intestinal lipase
Fats Fatty acids + Glycerol
Ileum
• Absorbs digested food into blood. (ABSORPTION)
• Have adaptive features that facilitate absorption of digested food into blood due to
- surface area
- thickness of the membrane
- length of small intestine
- presence of capillaries
The villi have thin walls/membranes i.e. epithelium is one-cell thick which allows
digested food to pass through quickly across the wall of the ileum into the blood.
The length of the small intestine is long to provide sufficient time for absorption.
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The intestinal wall and the villi have many capillaries to carry away the absorbed
food.
Structure of ileum
Colon
• Absorbs water and mineral salts from undigested matter into bloodstream.
(ABSORPTION)
Rectum
• Stores faeces which are mainly undigested food, mucus, dead cells, bile pigments
and germs.
Anus
• To expel faeces. (EGESTION)
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Associated Organs and its functions
1. Carbohydrate metabolism
2. Fat metabolism
3. Breakdown of red blood cells
4. Metabolism of amino acids and the formation of urea
5. Breakdown of alcohol, including the effects of excessive alcohol consumption
1. Carbohydrate metabolism
The glucose that leaves the liver will be used to provide energy for respiration in
living cells.
2. Fat metabolism
• RBC is destroyed in the spleen and the haemoglobin is sent to the liver which is
broken down by liver, to produce bile pigment, bilirubin.
• Iron released from RBC is stored in liver.
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• Excess amino acids are deaminated to form glucose and urea.
• The liver converts harmful substances into harmless ones by the process called
detoxification.
• Alcohol is broken down in liver to compounds that can be used in respiration to
provide energy.
• The effects of excessive alcohol consumption includes:
- stimulation of acid secretion in stomach that leads to risk of gastric ulcers
- Cirrhosis of liver ( a disease in which the liver cells are destroyed and replaced
by fibrous tissue) leading to liver failure and death
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Gall Bladder
• Stores bile that is produced from the liver and releases into duodenum when
needed.
Pancreas
• Secretes pancreatic juice which is alkaline.
The liquid contains enzymes that digest carbohydrates, proteins and lipids.
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