Rez Gioz P.

Apego January 23, 2014 N-40 Patients name: Antonieto, Buron Name of Drug Generic Name: Spironolactone Classification Mechanism of Action of Drug Therapeutic: Spironolactone acts Potassiumon the distal renal sparing tubules as a diuretic, competitive Aldosterone antagonist antagonist of aldosterone. It increases the excretion of sodium chloride and water while conserving potassium and hydrogen ions.

Indication Diagnosis and maintenance of primary hyperaldosteronism Adjunctive therapy in edema associated with CHF, nephrotic syndrome, hepatic cirrhosis when other therapies are inadequate or inappropriate Treatment of hypokalemia or prevention of hypokalemia in patients who would be at high risk if hypokalemia occurred: Digitalized patients, patients

Contraindications Anuria, hyperkalemia, acute or progressive renal insufficiency. Addisons disease.

Side Effects Fluid or electrolyte imbalance, gynecomastia, GI upset, drowsiness, headache, hyponatremia; tachycardia, hypotension, oliguria, hyperkalemia; confusion, weakness, paresthesia, hirsutism, mental disturbances, menstrual irregularities, loss of libido and impotence.

Nursing Responsibilities

Trade Name: Aldactone, Novospiroton Availability: Tablets: 25, 50, Pregnancy 100 mg Catergory D

History: Allergy to spironolactone; hyperkalemia; renal disease; pregnancy, lactation Give daily doses early so that increased urination does not interfere with sleep.

Make suspension as follows: Tablets may be pulverized and given in cherry syrup for young children. This suspension is stable for 1 mo if refrigerated.

Measure and record regular weight to monitor mobilization of edema fluid.

with cardiac arrhythmias

Avoid giving food rich in potassium. Arrange for regular evaluation of serum electrolytes and BUN.

Essential hypertension, usually in combination with other drugs

Chief complaint: Right cerebral tumor left sided weakness