BRIEF GLOBAL HEALTH SYNOPSIS: ACROSS-THE-BOARD ENVIRONMENTAL DISTURBANCE & REPLACEMENT VIA HUMAN ACTIVITIES. WHAT IS EXPECTED?

PANDEMICS OF ANIMAL DISEASES (MAD COW, FOOT & MOUTH, BIRD & PIG INFLUENZA) & HUMAN DISEASES/DYSFUNCTION (SARS, LYME, WEST NILE VIRUS, PESTICIDE & CHEMICALLY-INDUCED MISCARRIAGES, ADHD, CANCERS, HIV/AIDS, EBOLA, MOTOR NEURONE DISEASE, INFERTILITY, MCS/METABOLIC SYNDROME, LUPUS, etc) By Murray Thompson (BAppSci Environmental Health 1998, University of Western Sydney) http://poisoningandlegalaction.com.au http://poisonedpeople.com http://indiegogo.com/poisoned-people http://murraythompsongraphics.x90x.net Essay URL: http://poisonedpeople1.wordpress.com/2012/10/14/pandemic/ Short link: http://wp.me/s2DVqC-pandemic Diseases today are a factor of the meshing of many dynamics. 1.0 Foundational Precursors of Future Events Here are some of the prominent factors now bringing about a rapid alteration of older, long-time established disease patterns: 1. The doubling of global population before 2015. 2. From 1990 to 2020 developing countries will see the proportion of their total populations that inhabit urban areas increase from approximately 37% to 52%. 3. Globally (in developing and developed countries), health problems as a function of environmental pollution are likely to amplify. 4. Environmental change, as a function of increasing global temperatures, will occur. 5. Zoonotic disease [inter-species infectious diseases] patterns will change. There is an increasing incidence of newly recognized or emerging, or re-emerging older diseases. Alterations of the natural environment, including the replacement of formerly uninhabited areas with human settlements [see my Essay: http://poisonedpeople1.wordpress.com/2012/10/14/many-diseases-come-from-a-disturbed-nature/], are prominent causes here. Also, greater demands for animal protein, intensive animal production, and an amplification of the live animal trade (including animal products) are contributors (World Health Organization 2002:10). 6. As a further expansion of the third point above, there is the matter of pesticide and other chemically-induced and/or aggravated disease. First: "In the United States, more than 18,000 products are licensed for use, and each year > 2 billion pounds of pesticides are applied to crops, homes, schools, parks, and forests" (Kamel & Hoppin, 2004). Cancers, foetal death, miscarriages, premature births (NCAP, 1999:3; Bonn, 2005; Cox, 2004) and ADHD (Cox, 2004) are all now linked to pesticides. Further: "Animal data and in-vitro work suggest that chronic pesticide exposures might be tied to learning and behavioral problems, such as attention deficit hyperactivity disorder (ADHD) and other neuropsychological deficits" (Ashley, et al. 2006:7, citing Chanda et al., 1996; Rice et al., 2000). There are increased stillbirth rates with proximity to agricultural areas using organophosphate - pyrethroid carbamate - or chlorinated pesticides (Sinclair & Pressinger, no date, citing Bell, et al., 2001). Pesticides are strongly linked to birth defects (Montague, 2001).
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 "Two separate studies in Sweden have linked exposure to Glyphosate to Hairy Cell Leukemia and Non Hodgkin's Lymphoma. These types of cancers were extremely rare, however Non-Hodgkin's Lymphoma is the most rapidly increasing cancer in the Western world. It has risen by 73% in the USA since 1973. Another study has found a higher incidence of Parkinson disease amongst farmers who used herbicides, including glyphosate" (Leu, 2007 citing Cox, 1998; Lehmann & Pengue, 2000; Nordstrom, et al., 1998; Hardell & Eriksson, 1999). Cox, 2004 and Vachani, 2007 also linked Roundup to Non-Hodgkin's Lymphoma. Roundup causes genetic mutations in cell tests (NCAP, 2000:2, citing Vigfusson & Vyse, 1980; Kale et al., 1995; Rank et al., 1993). It is "a known carcinogen, neurotoxin, irritant, and has been found to kill human embryonic cells, and can cause kidney and liver damage" (BeyondPesticides.org 2012). Roundup has been heavily implicated in thyroid, liver and pancreatic tumours in test animals (Cox, 1993:4, citing Dykstra & Ghali, 1991). Roundup is also now shockingly linked to Mad Cow's Disease (Rotella 2003), and to an increase in plant diseases (gmwatch.org 2010). MCS: "Multiple chemical sensitivity (1) (MCS), also known as chemical intolerance, multiple chemical sensitivities, chemical sensitivity, or toxicant induced loss of tolerance (TILT) is an illness or disease where previous chemical exposure appears to initiate the wide ranging sensitivities characteristic of MCS" (Pall 2009?a). As well, Chronic Fatigue Syndrome has been linked to "viral infection, bacterial infection, organophosphorus pesticide exposure, carbon monoxide exposure, ciguatoxin poisoning, physical trauma, severe psychological stress, toxoplasmosis (protozoan) infection, ionizing radiation exposure" (Pall 2009?b). Type 2 Diabetes, Insulin Resistance, and Metabolic Syndrome: "Recent epidemiological studies have found that background exposure to persistent organic pollutants (POPs)xenobiotics accumulated in adipose tissueis associated with type 2 diabetes, insulin resistance, and metabolic syndrome (13), suggesting that POPs may play a key role in their pathogenesis" (Lee, et al. 2008). Children, Pesticides & Neurological Development: "...given the toxicity of all insecticides toward some component of the nervous system (both central and peripheral nervous systems), it is believed that children are a vulnerable, at-risk population because complete development of the nervous system does not occur until late in childhood (Hall et al., 1997)... Extensive mammalian studies of organophosphate toxicity, in general, and chlorpyrifos toxicity, in particular, have suggested that neurotoxic effects can be expected from low dose/chronic exposures. In addition to inhibiting nerve transmission, organophosphates also interfere in the acquisition and development of new brain cells and inhibit DNA synthesis (Whitney et al., 1995; Dam et al., 1998; Li and Casida, 1998). These functions are critical to proper neurological development, especially with respect to cognitive functions (Rice and Barone, 2000; Weiss, 2000)" (Ashley, et al. 2006:7). Motor neurone disease: "Most studies have focused on organophosphate insecticides, but some found neuro-toxic effects from other pesticides, including fungicides, fumigants, and organochlorine and carbamate insecticides. Pesticide exposure may also be associated with increased risk of Parkinson disease; several classes of pesticides, including insecticides, herbicides, and fungicides, have been implicated" (Kamel & Hoppin, 2004). Autoimmune diseases: The findings of a study linked environmental pesticide exposure to the development of autoimmune rheumatic diseases (Parks, et al. 2011). As well, a study of 75,000 women who used insecticides inside the home and in the garden demonstrated a strong link between the pesticides and the autoimmune diseases rheumatoid arthritis and lupus (Laino, 2009). 7. And we have not here even begun to touch upon a whole other world of disease pain in terms of medicationinduced disease. Note Thalidomide as a matter of historical course, and the recent exposition of the link between Acetaminophen (paracetamol) use, measles-mumps-rubella vaccination, and autistic disorder: "Acetaminophen use after measles-mumps-rubella vaccination was significantly associated with autistic disorder when considering children 5 years of age or less" (Schultz, et al., 2008). In brief summary at this point: "Most tragically, suffering, illness and disease surround us today in a way we would not have imagined a half century ago. We have banished some diseases only to have them replaced by a grumbling yet profound toxicity which is stripping our children of their rightful future" (Donohoe, 1998:38). That "grumble" is now accelerating into an across-the-board pandemic roar!

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2.0 Developments and Amplifications The overall outcome is inevitable. Changing human disease patterns will be impacted by "high population densities, movements of human populations within and between countries, and changes in lifestyles [consider war and refugee movements here, too]. Infectious diseases will remain the major causes of mortality in most developing countries, with human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS) and opportunistic infections (including zoonoses) being especially important. The problem will be exacerbated as the proportion of immunosuppressed people in the population increases" (World Health Organization 2002:10). What we are witnessing today is a massive and global synergy of immunosuppression (on a basis of profligate toxic chemical usage) and disease emergence and amplification. "Two examples of zoonotic diseases that have recently become prominent are Lyme disease and West Nile virus. Both of these diseases have their roots in animal populations and apparently were only recently transferred to human populations" (Pierce County Washington 2002:4). How recently? "Although Allen Steere [professor of rheumatology at Harvard University] realized that Lyme disease was a tickborne disease in 1978, the cause of the disease remained a mystery until 1981, when B. burgdorferi was identified by Willy Burgdorfer" (http://en.wikipedia.org 2012a). "West Nile virus was first identified in 1937 in Uganda in eastern Africa. It was first discovered in the United States in the summer of 1999 in New York" (National Center for Biotechnology Information 2010). "West Nile virus (WNV) is a mosquito-borne zoonotic arbovirus" (http://en.wikipedia.org 2012b). As well, there is, notably, SARS. "Between November 2002 and July 2003, an outbreak of SARS in Hong Kong nearly became a pandemic, with 8,422 cases and 916 deaths worldwide..." (http://en.wikipedia.org 2012c). These are just three examples of diseases breaking out of nature and releasing into human populations. And these may be "nothing" in comparison to a filovirus called "Ebola". The kill rate in humans for Ebola Zaire is nine out of ten. It is a slate wiper in humans, so in a sense, the earth is mounting an immune response against our human species (Preston 1994:319-20). 3.0 "Armed" Inevitabilities We have backed ourselves into a corner from which THERE IS NO ESCAPE. A global and aberrant overpopulation dynamic saturated in chemical toxicants is leading an accelerating and catastrophic wave of incursion into forested and other natural areas, environments ALREADY RADICALLY AFFECTED BY GLOBAL POLLUTION. Affected in what way? Viruses locked away deep in nature have been "washed" for decades by air pollution. Thus, they have been "pre-armed" with chemical resistance and are now releasing into indigenous (and other) human communities that are infectiously compliant due to broad immunosuppression. See how mining pollutes lands and leaves indigenous populations devastated in this Essay: http://poisonedpeople1.wordpress.com/2012/10/14/mining-destroys-environmental-health-creates-martianwastelands-human-health-human-rights. What I did not address in this particular Essay is the resulting immunosuppression amongst the 'locals', those closest to the rainforest who can be the first to transmit the start of an epidemic. Further, these populations, thanks to modern transport, are not far removed at any point on this globe from extensive land travel opportunities and then, in terms of intersection, international travel vectors via others who can afford to do so. As well, this immunosuppression is fatally backed by antibiotic resistance. In regard to antibiotics and our, especially, CORPORATE (Big Ag, Biotech, Big Pharma) proclivity for assuming that control is best: Unfortunately, we played a trick on the natural world by seizing control of these [natural] chemicals, making them more perfect in a way that has changed the whole microbial constitution of the developing

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countries. We have organisms now proliferating that never existed before in nature. We have selected them. We have organisms that probably caused a tenth of a percent of human disease in the past that now cause twenty, thirty percent of the disease that were seeing. We have changed the whole face of the earth by the use of antibiotics (Garrett 1994:437, quoting Lappe & Collins 1979). Further: Bacteria that have developed immunity to antibiotic drugs pose a large and growing threat to the success of modern medicine. These studies demonstrate that antibiotic resistance is literally streaming across America and what has not been appreciated is the extent of contamination (American Society of Microbiology 1999). 4.0 Perfect Storm The human corporate biotech miasma of "greed, corruption, arrogance, tyranny, and callousness" leads us today into inevitable perfect storm opportunities: pathogens can and will rapidly and extensively populate and dominate the world becoming the new numero uno apex predator. This is PANDEMIC. REFERENCES American Society of Microbiology 1999, Science News, June 5. Ashley, P. [Peter], Nishioka, M. [Marcia], Wooton, M.A [Maureen], Zewatsky, J. [Jennifer], Gaitens, J. [Joanna], and Anderson, J. [Jack], 2006 [Online]. "Healthy Homes Issues: Pesticides in the Home Use, Hazards, and Integrated Pest Management"; U.S. Department of Housing and Urban Development; HUD.GOV: Secretary Shaun Donovan; Office of Healthy Homes and Lead Hazard Control Washington DC 20410. Source: http://portal.hud.gov/hudportal/documents/huddoc?id=DOC_12484.pdf; accessed: 22 Oct. 2012. Biotechnology Information 2010 [Online]. Article: "West Nile Virus", in PubMed Health, A.D.A.M. Medical Encyclopedia; Source: http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0004457/; accessed: 10 October, 2012). Chanda, S.M. and C.N. Pope. 1996. Neurochemical and neurobehavioral effects of repeated gestational exposure to chlorpyrifos in maternal and developing rats. Pharmacology Biochemistry and Behavior. 53: 771-776. Dam, K., Seidler, F.J., and T.A. Slotkin. 1998. Developmental neurotoxicity of chlorpyrifos: delayed targeting of DNA synthesis after repeated administration. Developmental Brain Research. 108: 39-45. Garrett, L. [Laurie] 1994. The Coming Plague: Newly Emerging Diseases In A World Out Of Balance, Farrar Straus & Giroux. Garret, L. 2001. Betrayal of Trust: The Collapse of Global Public Health. Hyperion. http://en.wikipedia.org 2012a [Online]. Article: "Lyme disease"; Source: http://en.wikipedia.org/wiki/Lyme_disease; accessed: 10 October, 2012. http://en.wikipedia.org 2012b [Online]. "West Nile Virus"; Source: http://en.wikipedia.org/wiki/West_Nile_virus; accessed: 10 October, 2012b. http://en.wikipedia.org 2012c [Online]. "Severe acute respiratory syndrome"; Source: http://en.wikipedia.org/wiki/Severe_acute_respiratory_syndrome; accessed: 12 October 2012. Kamel, F. [Freya] & Hoppin, J.A. [Jane] 2004 [Online]. "Association of Pesticide Exposure with Neurologic Dysfunction and Disease"; ehp Environmental Health Perspectives; Environ Health Perspect. 2004 June; 112(9): 950958. Published online 2004 May 20. doi: 10.1289/ehp.7135. Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1247187/; accessed: 15 October 2012. Laino, C. [Charlene] 2009 [Online]. "Insecticides May Raise Risk of Lupus, RA. Study Shows Increased Risk of

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Autoimmune Diseases in Women Who Use Insecticides". WebMD Health News; Source: http://lupus.webmd.com/news/20091020/insecticides-may-raise-risk-of-lupus-ra; accessed: 15 October 2012. Lappe, F.M. & Collins, J. 1979, World Hunger: Ten Myths, Institute for Food and Development Policy, San Francisco, Calif. (USA). Lee, D. [Duk-Hee, Jacobs (Jr.), D.R. [David] & Steffes, M. [Michael], 2008 [Online]. "Association of Organochlorine Pesticides with Peripheral Neuropathy in Patients with Diabetes or Impaired Fasting Glucose"; Diabetes. 2008 November; 57(11): 31083111. doi: 10.2337/db08-0668. Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2570408/; accessed: 15 October 2012. Pall, M.L. [Martin; Professor Emeritus of Biochemistry and Basic Medical Sciences, Washington State University and Research Director of the Tenth Paradigm Research Group] 2009?a [Online]. "Multiple Chemical Sensitivity: Toxicological and Sensitivity Mechanisms"; Source: http://www.thetenthparadigm.org/mcs09.htm; accessed: 15 October 2012. Pall, M.L. [Martin; Professor Emeritus of Biochemistry and Basic Medical Sciences, Washington State University and Research Director of the Tenth Paradigm Research Group] 2009?b [Online]. "Novel Disease Paradigm Produces Explanations for a Whole Group of Illnesses. A Common Causal (Etiologic) Mechanism for Chronic Fatigue Syndrome/Myalgic Encephalomyelitis, Multiple Chemical Sensitivity, Fibromyalgia and Post-Traumatic Stress Disorder"; Source: http://www.thetenthparadigm.org/; accessed: 15 October 2012. Parks, C.G., Walitt, B.T., Pettinger, M., Chen, J.C., de Roos, A.J., Hunt, J., Sarto, G., & Howard, B.V., 2011 [Online]. "Insecticide use and risk of rheumatoid arthritis and systemic lupus erythematosus in the Women's Health Initiative Observational Study". Arthritis Care Res (Hoboken). 2011 Feb;63(2):184-94. doi: 10.1002/acr.20335. Source: http://www.ncbi.nlm.nih.gov/pubmed/20740609; accessed: 15 October 2012. Pierce County Washington 2002 [Online]. "EPIDEMIC (ANIMAL AND HUMAN)"; Source: http://www.co.pierce.wa.us/xml/abtus/ourorg/dem/EMDiv/HIVA/epidemic.pdf; accessed: 10 October 2012. Preston, R. 1994. The Hot Zone, Transworld Publishers (Doubleday), Moorebank NSW Australia. Rice, D., and S. Barone. 2000. Critical periods of vulnerabilities for the developing nervous system: Evidence from humans and animal models. Environmental Health Perspectives. 108(Supplement 3): 511-534. Schultz, S.T. [Stephen], Klonoff-Cohen, H.S. [Hilary], Wingard, D.L. [Deborah], Akshoomoff, N.A. [Natasha], Macera, C.A. [Caroline] & Ji, M. [Ming], 2008 [Online]. "Acetaminophen (paracetamol) use, measles-mumpsrubella vaccination, and autistic disorder. The results of a parent survey". Autism May 2008 vol. 12 no. 3 293-307; Source: http://aut.sagepub.com/content/12/3/293.short; accessed: 14 Oct. 2012. World Health Organization 2002 [Online]. WHO Technical Report Series 907: "FUTURE TRENDS IN VETERINARY PUBLIC HEALTH"; Source: http://whqlibdoc.who.int/trs/WHO_TRS_907.pdf; accessed: 10 October 2012.

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