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FACULTY OF PHARMACY UNIVERSITI TEKNOLOGI MARA (UiTM) COURSE PLAN 2013/14 COURSE NAME COURSE CODE : :

PHYSICO-CHEMICAL BASIS FOR PHARMACY

PHC 400 Mdm Salizatul Ilyana bt Ibrahim (SLZ) 1. Prof. Dr. Mohamed Salama Mohamed (SLM) 2. Dr. Minaketan Triparthy (MKT) 3. Dr. Khuriah bt Abdul Hamid (KAH) 4. Mr. Tommy Julianto Bustami Effendi (TJ) 5. Mdm Amlizan bt Ramli (AMZ) 6. Mdm Nor Khaizan bt Anuar (KZN)

COURSE COORDINATOR : LECTURERS :

COURSE OBJECTIVES

At the end of this course, the students should be able to: 1. understand the basic concepts of atomic theory, chemical and ionic equilibrium, phase equilibrium, chemical kinetics, thermodynamic and electrochemistry. 2. distinguish the three phases of matters, ideal and non ideal solution in terms of the interactions.

ASSESSMENT
Students will be assessed as follows: Continuous Assessment Test Assignments Final Total 20% 20% 60% ------100% -------

TEXTBOOK 1. Florence, A. T. & Attwood, D. 1998. Physico-Chemical Principles of Pharmacy. 3rd Edition, London, MacMillan Press. Amiji, M. A. & Sandmann, B. J. (Eds.) 2003. Applied Physical Pharmacy, New York: McGraw-Hill. Martin, S. & Cammarata, 1993. Physical Pharmacy. 4th Edition, Philadelphia, Lea Febiger.

2. 3.

REFERENCES

1. 2. 3. 4. 5. 6. 7. 8.

Aulton, M. E. 2002. Pharmaceutics The Science of Dosage Form Design. 2nd Edition Leicester, Churchill Livingstone. Banker, G. S. & Rhodes, C. T. 1990. Modern Pharmaceutics. 2nd Edn. London, Pitman Medical. Wallwork, S. C. & Grant, J. W. 1977. Physical Chemistry for Students of Pharmacy and Biology. 3rd edition Longman. Atkins, P. W. 1994. Physical Chemistry. 5th edition. Oxford University Press. Connors, C. A., Amindon, G. L. & Stella, V. J. 1985. Chemical stability of Pharmaceuticals. New York. John Wiley & Sons. J. G. Morris. 1974. A Biologists Physical Chemistry, 2nd edition, Edward Arnold, London. Cairns, D. 2000. Essentials of Pharmaceutical Chemistry, Pharmaceutical Press, London. Williams, V. R. & Williams, H. B. 1967. Basic Physical Chemistry for the Life Sciences. W. H. Freeman And Company, San Francisco.

COURSE PLAN SEMESTER SEPT 2013 - JAN 2014 Course Schedule

Week Date Lecture Title Stoichoimetry - Atomic theory - Molecular weight calculations and molecular formula. - The mole concept. - Chemical equation and Stoichiometric calculations. Chemical equilibrium. - Nature of chemical equilibrium. - Equilibrium constants. Ionic equilibrium in solutions. - Fully soluble salts and Acid base titration. - Buffer solution. - Hydrolysis. Gaseous phase - The ideal gas and non-ideal gas law. - Kinetic molecular theory of gases, pressure law. Liquid and solution phase - Kinetics of liquid. - Equilibrium phase. MID SEM BREAK (Hari Raya Aidil Adha: 15 Oct 2013) Properties of solutions. - Ideal solution and non-ideal solutions. - Solubility - Colloid. TEST 1 (TJ, KZN, AMZ & SLM) Chemical kinetics. - Effects of concentrations, - rate of reactions and equilibrium. - Collision theory, Effect of heat. - Catalyst. Chemical thermodynamic - System and its functions. - First law. - Enthalpy and heat capacity. - Enthalpy change in chemical reactions. Lecturer

9 - 13 Sep 2013

TJ

16 20 Sep 2013 23 27 Sep 2013

KZN

KZN

30 Sep 4 Oct 2013 7 11 Oct 2013 14 20 Oct 2013 21 25 Oct 2013 28 Oct 1 Nov 2013 4 8 Nov 2013 11 15 Nov 2013

AMZ

SLM

(1 week)

SLM TJ, KZN, AMZ, SLM MKT

MKT

10

18 22 Nov 2013

SLZ

11

12

13

14 15

Second law entropy. - Free energy and spontaneous change. Free law and equilibrium constant. Electrochemistry. - Electrical conduction. 2 6 Dec 2013 Electrolysis. Galvany cell. - Electrode potential. 9 13 Dec 2013 - Nernst equation. - Potentiometric titration. TEST 2 16 20 Dec (MKT, SLZ & KAH) 2013 REVISION WEEK 23 29 Dec 2013 FINAL EXAMINATION 30 Dec 2013 19 Jan 2014 20 Jan 30 SEMESTER BREAK March 2014 25 29 Nov 2013

SLZ

KAH

KAH

MKT, SLZ, KAH (1 weeks) (3 weeks) (6 weeks)