Lumbar spinal stenosis

Lumbar spinal stenosis

Classification and external resources

Lumbar spinal stenosis (LSS) is a medical condition in which the spinal canal narrows and compresses the spinal cord and nerves at the level of the lumbar vertebra. This is usually due to the common occurrence of spinal degeneration that occurs with aging. It can also sometimes be caused by spinal disc herniation, osteoporosis or a tumor. In the cervical (neck) and lumbar (low back) region it can be a congenital condition to varying degrees. It is also a common symptom for those who suffer from various skeletal dysplasias such as with pseudoachondroplasia and achondroplasia at an early age. Spinal stenosis may affect the cervical or thoracic region in which case it is known as cervical spinal stenosis or thoracic spinal stenosis. In some cases, it may be present in all three places in the same patient. Lumbar spinal stenosis results in low back pain as well as pain or abnormal sensations in the legs, thighs, feet or buttocks, or loss of bladder and bowel control. Signs and symptoms[edit] Understanding the meaning of signs and symptoms for the clinical syndrome of lumbar stenosis requires an understanding of what the syndrome is, and the prevalence of the condition. A recent review on lumbar stenosis in the Journal of the American Medical Association's "Rational Clinical Examination Series"
[1]

emphasized that the

syndrome can be considered when lower extremity pain occurs in combination with back pain. This syndrome occurs in 12% of older community dwelling men
[2]

and up to 21% of those in retirement communities.

[3]

The leg symptoms in lumbar spinal stenosis (LSS) are similar to those found with vascular claudication, giving rise to the term pseudoclaudication.
[4]

These symptoms include pain, weakness, and tingling of the legs,

[5]

[4]

and "radiation

down the posterior part of the leg to the feet".

Additional symptoms in the legs may be fatigue, heaviness,

[5]

weakness, a sensation of tingling, pricking, or numbness and leg cramps, as well as bladder symptoms.

Symptoms

are most commonly bilateral and symmetrical, but they may be unilateral; leg pain is usually more troubling than back pain.
[5]

Pseudoclaudication, now referred to as neurogenic claudication, typically worsen with standing or walking and improve with sitting. The occurrence is often related to posture and lumbar extension. Lying on the side is often more comfortable than lying flat, since it permits greater lumbar flexion. Vascular claudication "can mimic spinal stenosis" and some individuals experience unilateral or bilateral symptoms radiating down the legs "rather than true claudication".
[6]

"In contrast to those with vascular claudication, sitting but not standing will relieve symptoms; walking

uphill will be better tolerated than downhill walking; and exercise on a stationary bicycle in a seated flexed position will be better tolerated than walking in the erect position."
[5]

The first symptoms of stenosis include bouts of low back or neck pain. After a few months or years, this may progress to claudication. The pain may be radicular, following the classic neurologic pathways. This occurs as the spinal nerves or spinal cord become increasingly trapped in a smaller space within the canal. It can be difficult to determine whether pain in the elderly is caused by lack of blood supply or stenosis; testing can usually differentiate between them but patients can have both vascular disease in the legs and spinal stenosis.
[citation needed]

Among people with lower extremity pain in combination with back pain, lumbar stenosis as the cause is two times more likely
[clarification needed]

in those older than 70 years of age while those younger than 60 years it is 0.40 as likely.

The character of the pain is also useful. When the discomfort does not occur while seated, the likelihood of LSS increases considerably around 7.4 times. Other features increasing the likelihood of lumbar stenosis are improvement in symptoms on bending forward 6.4 times, pain that occurs in both buttocks or legs 6.3 times, and the presence of neurogenic claudication 3.7 times.
[1]

Alternately, the absence of neurogenic claudication makes lumbar stenosis much

[7]

less likely as the explanation for the pain. Causes[edit]

Spinal stenosis may be congenital (rarely) or acquired (degenerative), overlapping changes normally seen in the aging spine, "resulting from degenerative changes or as consequences of local infection, trauma or surgery".
[5][6]

"Degeneration is believed to begin in the intervertebral disk where biochemical changes such as cell

death and loss of proteoglycan and water content lead to progressive disk bulging and collapse. This process leads to an increased stress transfer to the posterior facet joints, which accelerates cartilaginous degeneration, hypertrophy, and osteophyte formation; this is associated with thickening and buckling of the ligamentum flavum. The combination of the ventral disk bulging, osteophyte formation at the dorsal facet, and ligamentum flavum hyptertrophy combine to circumferentially narrow the spinal canal and the space available for the neural elements. This

compression of the nerve roots of the cauda equina leads to the characteristic clinical signs and symptoms of lumbar spinal stenosis."
[6]

Degenerative spondylolisthesis[edit] Forward displacement of a proximal vertebra in relation to its adjacent vertebra in association with an intact neural arch, and in the presence of degenerative changes is known as degenerativespondylolisthesis.
[8][9]

Degenerative

spondylolisthesis narrows the spinal canal and symptoms of spinal stenosis are common. Of these, neural claudication is most common. Any forward slipping of one vertebra on another can cause spinal stenosis by narrowing the canal. If this forward slipping narrows the canal sufficiently, and impinges on the contents of the spinal column, it is spinal stenosis by definition. If there are associated symptoms of narrowing, the diagnosis of spinal stenosis is confirmed. With increasing age, the occurrence of degenerative spondylolisthesis becomes more common. The most common spondylolisthesis occurs with slipping of L4 on L5. Frymoyer showed that spondylolisthesis with canal stenosis is more common in diabetic women who have undergone oophorectomy(removal of ovaries). The cause of symptoms in the legs can be difficult to determine. A peripheral neuropathy secondary to diabetes can have the same symptoms as spinal stenosis. Ankylosing spondylitis[edit] Main article: Ankylosing spondylitis
[10]

Drawing of a lumbar disc herniation which can cause a localized stenosis. Thoracic discs though rare are similar.

L5 S1 Spondylolisthesis Grade II with forward slipping of L5 on S1 <50%.

Lumbar spine showing advanced ankylosing spondylitis which can lead to spinal stenosis. Diagnosis[edit]

Normal lumbar vertebra showing large, round spinal canal. The diagnosis is based on clinical findings; "neurologic findings on physical examination are unusual".
[6]

Some

patients can have a narrowed canal without symptoms, and do not require therapy. Stenosis can occur as either central stenosis (the narrowing of the entire canal) or foraminal stenosis (the narrowing of the foramen through which the nerve root exits the spinal canal). Severe narrowing of the lateral portion of the canal is called lateral recess stenosis". The ligamentum flavum (yellow ligament), an important structural component intimately adjacent to the posterior portion of the dural sac (nerve sac) can become thickened and cause stenosis. The articular facets, also in the posterior portion of the bony spine can become thickened and enlarged causing stenosis. These changes are often called trophic changes or facet trophism in radiology reports. As the canal becomes smaller, resembling a triangular shape, it is called a "trefoil" canal.
[citation needed]

The normal lumbar central canal has a midsagittal diameter (front to back) greater than 13 mm., with an area of 1.45 square cm. Relative stenosis is said to exist when the anterior-posterior canal diameter measures between 10 and 13 mm. Absolute stenosis of the lumbar canal exists anatomically when the anterior-posterior measurement is 10 mm. or less.
[11][12][13]

Plain x-rays of the lumbar or cervical spine may or may not show spinal stenosis. The definitive diagnosis is established by either CT (computerized tomography) orMRI scanning. Identifying the presence of a narrowed canal makes the diagnosis of spinal stenosis. Bicycle test of van Gelderen[edit]
[14][15][16]

In 1977, Dyck and Doyle

[17]

reported on the bicycle test of van Gelderen. The bicycle test is a simple procedure in

which the patient is asked to pedal on a stationary bicycle. If the symptoms are caused byperipheral vascular disease, the patient will experience claudication (def: limping; experienced as a sensation of not getting enough blood to the legs); if the symptoms are caused by lumbar stenosis, symptoms will be relieved when the patient is leaning forward while bicycling. Despite the fact that diagnostic progress has been made with newer technical advances, the bicycle test remains an inexpensive and easy way to distinguish between claudication caused by vascular disease and spinal stenosis. Dyck and Doyle wrote in their 1977 article: The authors describe a simple clinical adjunct to the routine neurological examination of patients with intermittent cauda equina compression syndrome. The "bicycle test" helps exclude intermittent claudication due to vascular insufficiency and frequently confirms the relationship of posture to radicular pain. Magnetic resonance imaging[edit] MRI is the preferred method of diagnosing and evaluating spinal stenosis of all areas of the spine, including cervical, thoracic and lumbar.
[18][19]

MRI is useful to diagnose cervical spondylotic myelopathy (degenerative arthritis of the

[20]

cervical spine with associated damage to the spinal cord).

The finding of degeneration of the cervical spinal cord

on MRI can be ominous; the condition is called myelomalaciaor cord degeneration. It is seen as an increased signal on the MRI. In myelopathy (pathology of the spinal cord) from degenerative changes, the findings are usually permanent and decompressive laminectomy will not reverse the pathology. Surgery can stop the progression of the condition. In cases where the MRI changes are due to Vitamin B-12 deficiency, a brighter prospect for recovery can be expected.
[21][22][23]

The detection of spinal stenosis in the cervical, thoracic or lumbar spine confirms only the anatomic presence of a stenotic condition. This may or may not correlate with the diagnosis of spinal stenosis which is based on clinical findings of radiculopathy, neurogenic claudication, weakness, bowel and bladder dysfunction, spasticity, motor weakness, hyperreflexia and muscular atrophy. These findings, taken from the history and physical examination of the patient (along with the anatomic demonstration of stenosis with an MRI or CT scan), establish the diagnosis.
needed] [citation

Management[edit] Nonoperative therapies and laminectomy are the standard treatment for LSS; recommend specific nonsurgical treatments".
[6] [24]

little "evidence is available to

A trial of conservative treatment including "activity modification, medications, physical therapy, home exercise therapy, and spinal injections" is recommended.
[6]

Individuals are generally advised to avoid stressing the lower back,

particularly with the spine extended. A physical therapy program to provide core strengthening and aerobic conditioning may be recommended and is considered useful, although "high-level evidence is lacking for the direct benefit of physical therapy or exercise".
[6]

Medication[edit] The evidence for the use of medical interventions for lumbar spinal stenosis is poor. nasal calcitonin may be useful for short term pain relief. there is no evidence of long-term effect.
[25] [25] [25]

Injectable but not

Epidural blocks may also transiently decrease pain, but

[25][26]

Adding steroids to these injections does not improve the result;

[6]

the

use of epidural steroid injections (ESIs) is controversial and evidence of their efficacy is contradictory.

Non-steroidal anti-inflammatory drugs (NSAIDs), muscle relaxants and opioid analgesics are often used to treat low back pain, but evidence of their efficacy is lacking and they should have a limited role in treatment. Surgery[edit] Surgery appears to lead to better outcomes if there are ongoing symptoms after three to six months of conservative treatment.
[27] [6]

Laminectomy is the most effective of the surgical treatments.

[24] [6]

In those who worsen despite Another procedure using an

conservative treatments surgery leads to improvement in 6070% of cases.

interspinous distraction device known as X-STOP was less effective and more expensive when more than one spinal level is repaired. Prognosis[edit] See also: Failed back syndrome Most people with mild to moderate symptoms do not get worse. this improvement decreases somewhat with time.
[6] [6] [24]

Both surgical procedures are more expensive than medical management.

[24]

While many improve in the short term after surgery

A number of factors present before surgery are able to predict the

outcome after surgery, with people with depression, cardiovascular disease and scoliosis doing in general worse while those with more severe stenosis beforehand and better overall health doing better.
[5]

The natural evolution of disc disease and degeneration leads to stiffening of the intervertebral joint. This leads to osteophyte formationa bony overgrowth about the joint. This process is called spondylosis, and is part of the normal aging of the spine. This has been seen in studies of normal and diseased spines. Degenerative changes begin to occur without symptoms as early as age 2530 years. It is not uncommon for people to experience at least one severe case of low back pain by the age of 35 years. This can be expected to improve and become less prevalent as the individual develops osteophyte formation around the discs.
[28]

In the US workers' compensation system, once the threshold of two major spinal surgeries is reached, the vast majority of workers will never return to any form of gainful employment. Beyond two spinal surgeries, any more are likely to make the patient worse, not better. Very few studies in the worldwide surgical literature actually document return to work after spinal surgery, or lack thereof.
[29]

Laminectomy

Laminectomy

Intervention

A laminectomy is a surgical procedure that removes a portion of the vertebral bone called the lamina. At its most minimally invasive, the procedure requires only small skin incisions. The back muscles are pushed aside rather than cut and the parts of the vertebra adjacent to the lamina are left intact. Recovery occurs within a few days.
[1]

The lamina is a posterior arch of the vertebral bone lying between the spinous process (which juts out in the middle) and the more lateral pedicles and the transverse processes of each vertebra. The pair of laminae, along with the spinous process, make up the posterior wall of the bony spinal canal. Although the literal meaning of laminectomy is 'excision of the lamina', a conventional laminectomy in neurosurgery and orthopedics involves excision of the posterior spinal ligament and some or all of the spinous process. Removal of these structures with an open technique requires disconnecting the many muscles of the back attached to them. A laminectomy performed as a minimal spinal surgery procedure is a tissue-preserving surgery that leaves more of the muscle intact and spares the spinal process. Another procedure, called the laminotomy, is the removal of a mid-portion of one lamina and may be done either with a conventional open technique or in a minimalistic fashion with the use of tubular retractors and endoscopes. A lamina is rarely, if ever, removed because the lamina itself is diseased. Instead, removal is done to break the continuity of the rigid ring of the spinal canal to allow the soft tissues within the canal to: 1) expand (decompress); 2) change the contour of the vertebral column; or 3) permit access to deeper tissue inside the spinal canal. A laminectomy is also the name of a spinal operation that conventionally includes the removal of one or both lamina, as well as other posterior supporting structures of the vertebral column, including ligaments and additional bone. The actual bone removal may be carried out with a variety of surgical tools, including drills, rongeurs and lasers. The success rate of a laminectomy depends on the specific reason for the operation, as well as proper patient selection and the surgeon's technical ability. The first laminectomy was performed in 1887 by DrVictor Alexander Haden Horsley, a professor of surgery at University College London. He was lauded for his breakthrough procedure.

A laminectomy can treat severe spinal stenosis by relieving pressure on the spinal cord or nerve roots, provide access to a tumor or other mass lying in or around the spinal cord, or help in tailoring the contour of the vertebral column to correct a spinal deformity such as kyphosis. A common type of laminectomy is performed to permit the removal or reshaping of a spinal disc as part of a lumbar discectomy. This is a treatment for a herniated, bulging, or degenerated disc. The recovery period after a laminectomy depends on the specific operative technique, with minimally invasive procedures having significantly shorter recovery periods than open surgery. Removal of substantial amounts of bone and tissue may require additional procedures such as spinal fusion to stabilize the spine and generally require a much longer recovery period than a simple laminectomy. If you also had spinal fusion, your recovery time may be longer. In some cases after laminectomy and spinal fusion, it may be several months before you can return to your normal activities. Infection, Blood clots, Nerve injury, Spinal fluid leak. For spinal stenosis[edit] Most commonly, a laminectomy is performed to treat spinal stenosis. Spinal stenosis is the single most common diagnosis that leads to spinal surgery, of which a laminectomy represents one component. The lamina of the vertebra is removed or trimmed to widen the spinal canal and create more space for the spinal nerves and thecal sac. Surgical treatment that includes a laminectomy is the most effective remedy for severe spinal stenosis; however, most cases of spinal stenosis are not severe enough to require surgery. When the disabling symptoms of spinal stenosis are primarily neurogenic claudication and the laminectomy is done without spinal fusion, there is generally a rapid recovery and long term relief. However, if the spinal column is unstable and fusion is required, the recovery period can last from several months to more than a year, and the likelihood of symptom relief is far less probable. Results[edit] In most known cases of lumbar and thoracic laminectomies,
[5] [4] [3] [2]

Potential complications include: Bleeding,

patients tend to recover slowly, with recurring pain or

spinal stenosis persisting for up to 18 months after the procedure. According to a World Health Organization census in 2001, most patients who had undergone a lumbar laminectomy recovered normal function within one year of their operation. Back surgery can relieve pressure on the spine, but it is not a cure-all for spinal stenosis. There may be considerable pain immediately after the operation, and pain may persist on a longer term basis. For some people, recovery can take weeks or months and may require long-term occupational and physical therapy. Surgery does not stop the degenerative process and symptoms may reappear within several years.
[6]