FAKULTAS KEDOKTERAN UNIVERSITAS SRIWIJAYA REMEDIAL MCQ AGUSTUS 2008 1. The disease based on Type II Hypersensitivity A.

. Urticaria (HS I) B. Granulo a !. IT" D. Myasth !"a G#a$"s The disease based on Type III Hypersensitivity A. SLE B. IT" !. Anaphyla$is Shoc% (HS I) &. Ane ia "erniciosa The disease based on Type I( Hypersensitivity A. Atopic &er atitis (HS I) B. Grave)s &isease (HS II) !. Good "asteur Syndro e (HS II) D. Ty% I D"a& t s M ''"t(s I uno+lobuline involved in Type I Hypersensitivity reaction A. I)E B. I+, (HS II) !. I+G (HS II) &. I+A I uno+lobuline involved in Autoi A. I)G a!* I)M B. I+A !. I+. &. I+& une He olytic Ane ia (HS II)

#.

'.

*.

-.

/.

.arly phase o0 Type I Hypesensitivity occurred A. L ss tha! 2 h+(#s B. # 1 #* hours !. *2 hours &. ,ore than / days The patho+enesis o0 "ost Streptococcal Glo erulonephritis A. D %+s"ts +, "--(! .+-%' / +! th )'+- #('a# &asa' - -&#a! B. &irect in0ection o0 Streptococcus !. I+A involved this disease &. Type I( Hypersensitivity "re0or ed ediator in the +ranules o0 A. 4eucotrien 0. 1"sta-"! !. Thro bo$anes &. "rosta+landine ast cell

3.

2.

5uestion 6o. 7 A 8o an9 #1 years old9 co e to the hospital 8ith the co plain o0 redness on the 0ace9 especially a0ter contact 8ith the sun rays9 she also have arthral+ia on the %nee and 0in+er9 and oral ulcer. 4aboratory ' ' 0indin+s reveal: Hb 39; +<dl9 leu%ocyte ';;;< 9 thro bocyte /-;;;< 9 proteinuria == (.sbach 1;;; +)9 anti ds &6A =. 7. The possible dia+nosis o0 this patient 8as A. Aplastic ane ia B. Acute +lo erulonephritis C. Syst -". L(%(s E#yth -at+s(s &. Autoi une Thro bocytopenic "urpura 6on speci0ic Hu oral I une Syste A. !o ple ent9 Inter0eron9 !>" B. Inter0eron9 !>" C. CR23 C+-%' - !t &. !o ple ent9 Inter0eron Speci0ic !ellular I A. !o ple ent B. 6? cell !. I+A D. T142 une Syste

1;.

11.

1#.

Spesi0ic Hu oral I une Syste A. I+A9 I+ ,9 I+ G B. I+,9 I+ G !. I+G9 I+ A &. I+ G9 TH # Speci0ic !ellular I une Syste A. Basophil B. ,ast cell !. 6? cell D. Cyt+t+/". T . '' The 0unctions o0 !o ple ent A. 4ysis B. !he ota$is !. @psonisation D. a5&5. The 0unctions o0 Inter0eron A. Activation o0 6? cell B. Induction o0 resistance !. Inhibitions o0 viral +ro8th D. a5&5. "las A. B. C. &.

1'.

1*.

1-.

1/.

a protein ediator role as che otactic 0actor 0or neutrophil is Serotonin ?alli%rein C+-%' - !t ,a.t+# 6C7a8 "rosta+landin

13.

A child 8ith ly phadenopathy o0 nec% under8ent biopsy. Histopatholo+ic 0eature sho8ed +ranulo atous in0la ation. The ost characteristic 0eature o0 +ranolo atous in0la ation is .. A. A))# )at"+! +, %h"t '+"* -a.#+%ha) s B. 6ecrosis !. ,ultinucleated +iant cells &. .osinophils

12.

A -7 year old an su00er a assive heart attac% and e$pires #* hours later due to ventricular arrhyth ia. Histolo+y e$a ination o0 the e00ected heart uscle at autopsy 8ould sho8 an abundance o0 8hich o0 the 0ollo8in+ in0la atory cells A. Aibroblast B. 4y phocytes !. ,acropha+es D. N (t#+%h"' Healin+ process o0 the hu an body is dependin+ on type o0 the cell 8ho)s +ettin+ inBury. >apidly re+eneration cells are A. Stables cells 0. La&"' . ''s !. "er anent cells &. 6eurons A #- year old 8o an develops a sore9 red9 hot9 s8ollen le0t %nee. She has no history o0 trau a and no 0a ilial history o0 Boint disease. Aluid aspirated 0ro the Boint space sho8s an abundance o0 se+ ented neutrophils. Transendothelial i+ration o0 acute in0la atory cells into the patient)s Boint space 8as ediated pri arily by 8hich o0 the 0ollo8in+ 0a ilies o0 proteins A. .ntactins 0. F"&#+! .t"!s !. Inte+rins &. Aibrillins A * year old boy 0all on a rusty nail and punctures is s%in. The 8ound is cleaned and covered 8ith sterile +auCe. Dhich o0 0ollo8in+ is the initial event in the healin+ process A. F+#-at"+! +, a ,"&#"! .'+t B. Accu ulation o0 acute in0la atory cells !. &eposition o0 proteo+ycans and colla+en &. &i00erentiation and i i+ration o0 yo0ibroblasts A *1 year old 8o an co plains o0 e$cessive enstrual bleedin+ and pelvic pain o0 * onths in duration. She uses an intraiterin device (IU&) 0or contraception. .ndo etrial biopsy sho8s an e$cess o0 plas a cells and acropha+es 8ithin the uterine stro a and scattered ly phoid 0ollicles. The presence o0 these cells 8ithin the stro a and scaterred ly phoid 0ollicles. The presence o0 these cells 8ithin the stro a is evidence o0 8hich o0 the 0ollo8in+ conditions A. Acute in0la ation B. !hronic in0la ation !. Granulation tissue D. G#a!('+-at+(s "!,'a--at"+!s The acute phase response consist o0 several clinical si+n li%es 0ever9 0atiEue9 anore$ia9 atc. A very i portant ediator o0 the syste ic e00ects in0la ation is A. Ga a inter0eron B. Interleu%inF# C. I!t #' (9"!4: &. Beta tu or necrosis 0actor &urin+ early in0la ation 0ollo8in+ ar+ination o0 leu%ocytes9 an i portant adhesive sur0ace protein on leu%ocytes is A. !o ple ent 0actor -a (!-a) 0. E!*+th '"a' ' (9+.yt a*h s"+! -+' .(' 6ELAM4:8 !. Tu or necrosis 0actor (T6T) &. 4eu%ocyte 0unction anti+entF1 (4AAF1)

17.

#;.

#1.

##.

#'.

#*.

#-.

The cells o0 the body are divided into ' +roupsG labile cells9 stable cells9 per anent cells9 8here are the stable cells have only lo8 level replicate capacity. Dhich one the 0ollo8in+ e$a ples are stable cells A. Hepatocytes and endothelial B. Hepatocytes and he atopoietic cells C. L !s a!* ! (#+!s . ''s &. ,ucosal and endocrine cells A '; year old 0ire 0i+hter su00ers e$tensive third de+ree burn over his ar and hands. This patients is at hi+h ris% 0or developin+ 8hich o0 0ollo8in+ co plication o0 8ound healin+ A. &ehiscence (pd pasien diabet) B. !ontracture (pe ende%an otot) C. K '+"* &. Trau atic neuro a The basic processes o0 healin+ have ' %ey cellular echanis G cell proli0eration9 e$tra cellular atri$9 and cellular i+ration. Dhich one o0 the 0ollo8in+ e$a ple is e$tra cellular atri$ A. Aibrin 0. E'ast"! !. Inte+rin &. 4a inin 4on+ ter conseEuence o0 postFstreptococcal disease A. 6ephrolithiasis B. !ystitis !. Tonsillopharyn+itis D. A.(t Rh (-at". F $ # Streptococcus that "ositive 0or 5U.44U6G test is A. S.%! (-+!"a B. S.bovis !. S.pyo+enes &. S.a+alactiae A %ind o0 enCy e produced by Group A Streptococci can be used to treat patients su00erin+ 0ro Heart Attac%. The enCy e na e is A. Hyaluronidase 0. St# %t+9"!as !. &6Ase &. Beta lacta ase "il+ri a+e to ,ecca (,e%ah) A. N.- !"!)"t"*"s B. S.aureus !. .nterococcus &. Gonococcus ust be vaccinated a+ainst bacteria

#/.

#3.

#2.

#7.

';.

'1.

'#.

"elvic In0la atory &isease ("I&) is usually caused by A. S.typhi 0. N.)+!+##h+ a !. S.aureus &. S.pyo+enes G#a- %+s"t"$ #+*s that cause Aood "oisonin+ A. B.subtilis B. B.anthracis C. 0.. # (s &. 4. onocyto+enes

''.

'*.

This species is usually connected to &"+t ##+#"s- A. !l. tetani 0. C'. 0+t('"!(!. !. diphtheriae &. B. anthracis "seudo e branous colitis is caused by A. !l. tetani 0. C'. *",,"."' !. !l. per0rin+ens &. !l. botulinu The one o0 clinical A. !ellulitis B. Bronchitis C. U# th#"t"s &. ,enin+itis !o A. B. !. D. ani0estation o0 Neisseria gonorrhoeae in0ection is

'-.

'/.

'3.

ponent o0 S.aureus cell)s 8all 8hich can bind to AcFI+G is Teichoic acid "eptido+lycan 4"S 2#+t "! A

'2.

"ha+ocytosis can be avoided by the 0unction o0 this co ponent. A. "olysaccharide capsule B. Ala+ella !. Spores D. L2S Gra A. B. C. &. Gra A. B. !. D. positive cocci arran+ed in +rapeli%e clusters Streptococci "eptostreptococci Sta%hy'+.+.." Gonococci positive !occi that *+ !+t produce !atalase S.aureus S.epider idis S.saphrophyticus S.%y+) ! s

'7.

*;.

*1.

Group o0 to$in in S.aureus that caused Aood "oisonin+ is A. E!t #+t+/"! B. To$ic Shoc% Syndro e To$in !. .$0oliatin &. 4eu%ocidin Urinary Tract In0ection in catheteriCed patients is usually caused by A. S.aureus B. S.epider idis C. S.sa%h#+%hyt".(s &. S.pneu oniae Streptococcus that)s included in 4ance0ield Group A A. ..0aecalis B. S.bovis !. S.a+alactiae D. S.%y+) ! s

*#.

*'.

**.

6on Spore0or in+ Gra (=) >ods that produced .$oto$in A. 4. onocyto+enes 0. C. *"%hth #"a !. !l. tetani $ &. B. anthracis $ This species do not produced any to$in A. !. diphtheriae 0. L. -+!+.yt+) ! s !. !l. tetani &. B. anthracis Anaerobic bacteria in this list is A. E. .+'" B. S. aureus !. 6. +onorrhoeae &. !l. tetani Intracellular Gra 6e+ative &iplococci is a characteristic o0 A. "eptostreptococcus B. S. a+alactiae C. N. )+!+##h+ a &. S. epider idis Gra A. 0. !. &. "ositive >od that +ro8 Intracellular is !.diphtheriae L.-+!+.yt+) ! s B.cereus !l.di00icile

*-.

*/.

*3.

*2.

*7.

The 0ollo8in+ in0ection is "redisposin+ Aactor 0or ,ycoses.. A. 1IV4AIDS B. Sal onellosis !. Shi+ellosis &. Brucellosis The 0ollo8in+ ycoses is trans itted by Geophylic A. !.albicans B. ..0loccosu !. H.capsulatu D. M..a!"s This 0un+us is 0ound in the 0or A. ,.canis B. ..0loccosu !. H.capsulatu D. C.a'&".a!s o0 Heast

-;.

-1.

-#.

This 0un+us is yeast 8ith capsule A. !.albicans 0. C.! +,+#-a!s !. B.der atitidis &. ".brasiliensis The species is included in the +roup o0 &i orphic Aun+i A. C. "--"t"s 0. C. a'&".a!s !. T. rubru &. ,. canis

-'.

-*.

The A. B. C. &.

ost co on ediu Blood a+ar ,ac!on%ey a+ar Sa&+(#a(* a)a# 6utrient

to +ro8 0un+i is

--.

&irect preparation 0or 0un+i laboratory dia+nosis A. Gra stain B. Iiehl 6eelsen !. 6eisser stain D. KO1 :0; 5 )'y. #"! Dhat is the characteristic o0 Plasmodium falcifarum A. .nlar+ed in0ected >B! 8ith double chro atin dots (". viva$) 0. N+ !'a#) - !t +, th "!, .t * R0C &(t <"th *+(&' .h#+-at"! *+ts !. Ai brae o0 the in0ected >B! &. A oeboid appearance o0 the cytoplas The distinct di00erence bet8een the li0e cycle Plasmodium vivax and Plasmodium falcifarum is the the e$istence o0..in the liver cells o0 viva$ alaria A. M #+=+"t B. HypnoCoyte !. !rescent +a etocytes &. &elicate rin+ The avera+e incubation period o0 Plasmodium falciparum is A. 'F* days 0. :04:2 *ays !. 1;F1# 8ee%s &. 1F* onths ,ode o0 in0ection o0 leis aniasis is by the A. Bite o0 tCetCe 0ly B. Bite o0 osEuito C. 0"t +, sa!*,'y &. Bite o0 treato a !oned nose 0ly is the vector o0 A. Trypanosoma gambiese B. Trypanosoma cruzi C. Trypanosoma rhodesiense D. Leismania donovani Trans ission o0 disease throu+h anteriostation develop ent A. !ha+as)s disease B. Trypanoso iasis rhodesiense !. Trypanoso iasis +a biense &. Trypanoso iasis rodensiense and +a biense 4ar+e %inetoplast is 0ound in . T. b. gambiense B. T. b. rhodesiesnse C. T. cruzi D. Toxoplasma gondidi The shape o0 ! is 0ound in the parasite o0 A. T. b. gambiense B. T. b. rhodesiense C. T. cruzi D. A-ast")+t

-/.

-3.

-2.

-7.

/;.

/1.

/#.

/'.

/*.

The habitat o0 Trypanosoma gambiense is in A. !onnective tissues B. !onnective tissues and ly ph nodes C. Ly-%h !+* s a!* &'++* st# a&. !onnective tissues9 ly ph nodes9 blood strea Jenodia+nosis is used 0or the dia+nosis o0 A. 4eish aniasis B. A0rican trypanoso iasis C. Cha)as>s *"s as &. ,alaria The disease based on Type I Hypersensitivity A. Autoi une He olytic Ane ia 0. 0#+!.h"a' Asth-a !. S4. &. !ontact &er atitis !o A. B. !. D. plications o0 typhoid 0ever9 e$ception "er0oration ,enin+itis !holecystitis C+!?(!t"$"t"s

and central nervous syste

/-.

//.

/3.

/2.

Several antibiotics are e00ective in enteric 0ever9 e$ception A. "enicillin B. !hlora phenicol !. coFtri o$aCole D. F'(+#+@("!+'+! s The prevention livin+ condition i prove reduce the incidence o0 typhoid A. SteriliCation o0 instru ent B. >outine Antibiotic !. Herbal ,edicine D. Sa!"tat"+! Travelers to countries 8here enteric 0ever in0ections are ende ic should be A. SteriliCation o0 instru ent B. >outine Antibiotic !. Herbal ,edicine D. Ty%h+"* $a.."! s >outine 4aboratory Aindin+s have si+ni0icantly the role out o0 dia+nosis typhoid A. >elative ly phocytosis 0. W"*a' t st !. Sal onella I+, &. "!> Hu A. B. !. &. an to$oplas osis can be contracted by the I!) st"+! +, (!* #*+! - at .+!ta"!"!) t"ss( .yst. In+estion o0 underdone eat containin+ tissue cyst or s8allo8in+ In+estion o0 isospora Bitten o0 cat.

/7.

3;.

31.

3#.

o0 oocyst

3'.

The clinical 0eature o0 to$oplas osis is A. Asy pto atic in child 0. Sy-%t+-at". "! a*('t !. Al8ays sy pto atic in con+enital in0ection &. Al8ays sy pto atic in con+enital in0ection and usually asy pto atic in

adult

3*.

The causative a+ent o0 espundia A. Leishmania donovani B. Leishmania !ropica C. Leishmania brasislsiensis D. Toxoplasma gondii The cardinal si+n on acute and active chronic in0la ation are rubor9 dolor9 calor9 and tu or. The cardinal si+n o0 in0la ation called rubor is ainly the result o0 A. Vas+'"*at"+! +, a#t #"+' s B. &ecreased interstitial hydrostatic pressure !. Increased vascular per eability o0 venules &. (asoconstriction o0 uscular arteries Activation o0 receptor H# can cause A. I une reaction 0. 0#+!.h+*"'at"+! !. (asoconstriction o0 A. !oroner and A. Basiler &. Itchin+ An e$a ple o0 the third +eneration o0 antihista ines is A. .thilendia ines B. "iperaCines !. "henotiaCines D. L $+."t"#"="! s &ru+ o0 choice 0or treatin+ >hinitis aller+ica chronic is 0. D"%h !h"*#a-"! !. !hlorphenira ines &. Ae%sophenadine .. 4evocabastine In hi+h doses9 this antihista ine can be used as an anesthetic local A. "ro ethaCines B. Terphenadine C. Etha!+'a-"! s &. Scopola ines Side e00ect o0 this second +eneration o0 antihista ines is cardiovascular disturbance A. &o$yla ines 0. A=t -"=+' !. 4evocetiriCine &. ,ecliCine ,uscarinic e00ect due to antihista ines utiliCation is A. Tre or 0. D#y -+(th !. &iCCiness &. Inso nia It)s action by inhibitin+ the contraction o0 +astric A. >anitidine B. !i etidine C. Fa-+t"*"! &. 6iCatidine The A. B. C. &. ost capability in reducin+ +astric Buice is C"- t"*"! Aa otidine Ra!"t"*"! "ro ethaCine uscle

3-.

3/.

33.

32.

37.

2;.

21.

2#.

2'.

2*.

This dru+ is a dru+ o0 choice 0or conBunctivitis aller+ica A. AntaColine B. Terphenadine !. &yphenhidra ines &. !etiriCines Glauco a is contraindicated to A. Terphenadine B. 4evocetiriCine !. 4oratadine D. 2#+- tha="! Aor radical treat ent is better usin+ A. 5uinine 0. 2#"-a@("! !. ,e0loEuine &. "yri etha ine This dru+ is not only used 0or A. !hloroEuine 0. 2y#"- tha-"! !. AtovaEuone &. ,e0loEuine alaria9 but also is used 0or to$oplas osis

2-.

2/.

23.

22.

This anti alaria dru+ could not be used 0or che oprophyla$is A. ,e0loEuine B. 5uinine !. !hloroEuine D. 2y#"- tha-"! This dru+ is contraindicated 0or psoriasis A. "ri aEuinine 0. Ch'+#+@("! !. "yri etha ine &. Arte isin Side e00ect o0 this anti alaria can cause 5T interval elevation A. AtovaEuone B. Arte isine C. M ,'+@("! &. "ri aEuine ,etochlopropa ide reduces it)s concentration in plas a A. AtovaEuone B. !linda ycines !. Sul0ona ide &. !hloroEuine It)s action by inhibitin+ o0 dehydro0olate reductase enCy e and ty idilate synthetase A. Ch'+#+)(a!" B. !hloroEuine !. Arte isine &. ACte isol This anti alaria could not be used to+ether 8ith Euinine A. ,e0loEuine B. "ri aEuine C. C'y!*a-"."! s &. &o$yla ine

27.

7;.

71.

7#.

7'.

7*.

This antibiotic is sa0e 0or treatin+ A. C'y!*a-"."! B. Tetracyclines !. Sul0on &. Arte isin Hae A. B. !. &.

alaria in pre+nant 8o an

7-.

olytic anae ia occurred i0 this dru+ is ta%en by G/"& patient 2#"-a@("! ,e0loEuine AtovaEuone "yri etha ine unolo+y syste be+ins 8hen the 0etus is

7/.

The develop ent o0 i 0. 2 A B -+!ths !. * 1 / onths &. 3 1 2 onths .. @ver 2 onths

73.

I+, receptor located in 0etus sur0ace cell 8hen the 0etus is A. 1; 8ee%s B. 1;.- 8ee%s !. 1# 8ee%s &. #; 8ee%s !ytoplas ic I+, located in.... A. Ste cell 0. 2# 0 . '' !. ,ature B cell &. "las a cell Hu A. B. !. D. oral speci0ic i I+G I+, I+. I)A une responds 0or bacteria in the ucosal layer

72.

77.

1;;. !ardinal si+n on acute in0la by A. 0#a*y9"!"! B. Hista ine !. "rosta+landin &. 4eu%otrienes

ation there are rubor9 dolor9 calor9 and tu or. &olor is

ediated

%alau ada y+ salah di%ore%si ya