Beruflich Dokumente
Kultur Dokumente
Professor Lecturer
Panata Migasena M.D., D.T.M.&H., Ph.D(Tropical Medicine) Karunee Kwanbunjan B.Sc.(Biology), M.Sc.(Tropical Medicine)
F.R.C.P. (T) Dr. oec. troph. (Nutrition and Food Sciences)
Praneet Pongpaew B.Sc.(Chemistry), M.Sc.(Biochemistry), e-mail : tmkkb@mahidol.ac.th
M.S.(Nutrition)
Scientist
e-mail : tmppp@mahidol.ac.th
Seevika Vorasanta B.Sc.(Nutrition), M.C.H.(Nutrition)
Associate Professor Pornrutsami Jintaridhi B.Sc. (Nursing), M.Sc. (Nutrition)
Niyomsri Vudhivai B.Sc.(Pharmacy), M.Sc.(Tropical Medicine) e-mail : tmpjt@mahidol.ac.th
Venus Supawan B.Sc.(Medical Technology), M.T.(ASCP)
Researcher
e-mail : tmvsp@mahidol.ac.th
Rungsunn Tungtrongchitr B.Sc.(Medical Technology), Anong Kitjaroentham B.Sc. (Medical Technology),
M.Sc.(Tropical Medicine), Ph.D.(Tropical Medicine) M.Sc. (Tropical Medicine)
e-mail : tmrtg@mahidol.ac.th e-mail : tmakj@mahidol.ac.th
TRAINING COURSES
Second International Short Training Course Food Safety and Food Control 1998
14-25 September 1998
28 Participants
WORKSHOP
ABSTRACTS
Niyomsri Vudhivai1, Praneet Pongpaew1, investigated were apparently healthy. The age of the
Rungsunn Tungtrongchitr1,Benjaluck Phonrat2, study group varied between 20 and 59 years. The
Vicha Horsawat1, Frank Peter Schelp3 median for the males was 44 years and for the females
1
Department of Tropical Nutrition and Food Science, Faculty of Tropical 37 years. Over- and undernutrition were found among
Medicine, Mahidol University, 420/6 Rajvithi road, Rajthevee,
Bangkok 10400, Thailand those investigated. 25.9% (BMI ≤ 20.1) of the males
2
Department of Clinical Tropical Medicine, Faculty of Tropical Medicine,
Mahidol University, 420/6 Rajvithi road, Rajthevee, Bangkok 10400,
and 1.8% (BMI ≤18.7) of the females were under-
Thailand nourished. 31.5 % of the males and 43.8 % of the
3
Department of Epidemiology, Institute of Social Medicine, Faculty of
Medicine, Free University, Berlin, Germany females were overnourished (BMI ≥ 25.0). 13.0% of
the males and 10.7% of the females had ∝EGR ≥1.30,
Anthropometric measurements, haematological or vitamin B2 insufficiency.
parameters and riboflavin status of Thai road
sweepers in Bangkok were determined. According to Published in : Intern Med 1997;13:77-80.
a physical check-up and X-rays taken, all individuals
enough to clearly see the outcome of the project. The vehicle for iodine fortification. The success of the
other possible contributing errors in this study is due project depended heavily on the understanding and
to intra observer variation of the palpation technique co-operation of the school teachers and the school
when the sample size is not big enough. Goitrogens children.
in this area might be another risk factor for the high Major constraints in conducting this project had
prevalence rate of the goitre. Further study in this been the insufficient distribution of iodinated salt and
field should be encouraged. potassium iodide solution for fortifying drinking
The results of the study indicate that iodine water and the inconsistency of iodide concentration
fortification of salt and fish sauce is more effective than in salt after fortification.
fortification of drinking water. Due to the local
preference to add fish sauce (nam pla) instead of salt Published in : Asia Pacific J Clin Nutr 1998;7:131-7.
to almost all dishes, nam pla proved to be the best
Praneet Pongpaew1, Rungsunn Tungtrongchitr1, ment, including hematological status, were performed.
Benjaluck Phonrat2, Venus Supawan1, Frank Peter Schelp3, There was a significant difference in the weight and
Chalor Intarakhao4, Udomsak Mahaweerawat4, height of the children from the four schools investi-
Sastri Saowakontha5
1
Department of Tropical Nutrition and Food Science, Faculty of
gated, before and after supplementation in each school.
Tropical Medicine, Mahidol University, 420/6 Rajvithi Road, Rajthevee, The prevalence of anemia, (as indicated by
Bangkok 10400, Thailand
2
Department of Clinical Tropical Medicine, Faculty of Tropical Medicine, hematological measurement) and iodine deficiency (as
Mahidol University, 420/6 Rajvithi Road, Rajthevee, Bangkok 10400,
Thailand
indicated by urinary iodine concentration in the
3
Department of Epidemiology, Institute of Social Medicine, children from the four schools) were assessed and
Free University, 12203 Berlin, Germany
4
Department of Community Medicine, Faculty of Medicine, compared before and after iodine supplementation; a
Khon Kaen University, Khon Kaen 40002, Thailand
5
Department of Medicine, Faculty of Medicine, Khon Kaen University,
decrease in prevalence was found in all school
Khon Kaen 40002, Thailand children. However, serum ferritin did not change
before and after supplementation in all school
To improve the health and nutritional status of children.
school children in an area of iodine deficiency
disorders (IDD) by means of different iodine Published in : Southeast Asian J Trop Med Public
fortifications in salt, fish sauce and drinking water, Health 1998;29:50-7.
anthropometric assessment for nutritional measure-
Praneet Pongpaew1, Rungsunn Tungtrongchitr1, salt is not the important factors for purchasing. About
Benjaluck Phonrat2, Chalor Intarakhao3, 48.8-60.0% of all villagers investigated did not use
Udomsak Mahaweerawat3, Yaowamarn Chantaranipapong1, iodized salt. They want to buy salt from village health
Venus Supawan1, Niyomsri Vudhivai1, Siriwan Tribunyatkul1,
volunteer and health officers. The major constraints
Sastri Saowakhontha3, Frank Peter Schelp5
for iodized salt preparation is an inadequate and
1
Department of Tropical Nutrition and Food Science, Faculty of
Tropical Medicine, Mahidol University, 420/6 Rajvithi Road, irregular supply of potassium iodate. The shortage of
Rajthevee, Bangkok 10400, Thailand
2
Department of Clinical Tropical Medicine, Faculty of Tropical Medicine,
iodized salt supplied to the village foodstore is also a
Mahidol University, 420/6 Rajvithi road, Rajthevee, Bangkok 10400, problem. The middleman preferred to sell rock salt
Thailand
3
Department of Community Medicine, Faculty of Medicine, Khon Kaen because they can make more profit. At the subdistrict
University
4
Department of Medicine, Faculty of Medicine, Khon Kaen University
/district level, the supply of potassuium iodate from
5
Department of Epidemiology, Institute of Social Medicine, the health promotion center is not enough for
Free University, Berlin, Germany
producing iodized salt. In addition, support and
The management of iodine fortifications and supervision from central organizations is inefficient,
iodinated salt distribution on village, subdistrict and amount other reason because the number of man
districts level in Khon Kaen province, northeast powers is limited. At the provincial and health
Thailand where the prevalence of iodine deficiency promotion center, the revolving fund and the stock
disorders is high, were investigated. 10 villages from of iodized salt are inadequate. Iodized salt produced
3 districts were selected at random. The information by large firm are in good quality whereas small salt
about the production, distribution and use of producer on a cottage scale supplied low quality salt
iodinated salt was collected from villagers, village to a rather high price. Production and distribution of
foodstore, provincial foodstore, subdistrict and iodized salt should be promoted and monitored
district health officers, provincial health officer, health better than at present in order to reach the
promotion center including producers through a population at village level.
prepared questionnaire. Proper knowledge and
attitude towards using iodized salt of villagers was Published in : J Public Health 1998 (in press).
found to be the range of 63.8-81.7%. The price of
Somchai Chanjanakijskul1, Rungsunn Tungtrongchitr2, markers for SLE were found to be 79, 13 and 13
Praneet Pongpaew2
percent respectively. The others non-specifics antibody
1
Section of Immunology, Institute of Dermatology, Ministry of
Public Health, 420/7 Rajvithi road, Rajthevee, Bangkok 10400.
for SLE: anti nRNP, Rh factor, FTA-Abs, RPR were
2
Department of Tropical Nutrition and Food Science, Faculty of found to be positive 21.0, 7.0, 3.0 and 7.0 percent
Tropical Medicine, Mahidol University, 420/6 Rajvithi road,
Rajthevee, Bangkok 10400 respectively. In cases of SLE patients with positive
ANA, the percentage of anti nRNP, anti Sm and anti
One hundred systemic lupus erythematosus nDNA were found to be 32.8, 20.3 and 20.3 percent
(SLE) patients from Institute of Dermatology, respectively. No other autoantibodies were found in
Bangkok were studied for serological autoantibodies SLE patients with the negative ANA in this study.
characteristics namely antinuclear antibodies (ANA), Therefore, ANA might be the most important
anti Sm, anti nRNP, anti nDNA, Rheumatoid factor autoantibody for screening in SLE patients.
(Rh factor), FTA-Abs and RPR. These patients aged
between 10 to 71 years old in both sexes. Positive Published in : Bull Med Tech Phy Ther 1998 (in press).
ANA, anti nDNA and anti Sm, the important
Kamron Chaisir1, Praneet Pongpaew2, the medians, of the relevant variables over the total
Rungsunn Tungtrongchitr2, Benjaluck Phonrat2, Sirikul Kulleap1, population is concerned. A rather high proportion of
Pannavadee Sutthiwong1, Chalor Intarakhao3, individuals was found to be overnourished and to have
Udomsak Mahaweerawat3, Wongsa Khongdee3, high triglyceride levels. Individuals with high
Pattara Sanchaisuriya3, Sastri Saowakontha3, Alfred Merkle4,
triglyceride levels run a risk of developing coronary
Frank Peter Schelp5
heart disease only when the LDL-HDL fraction is
1
Khon Kaen Provincial Health Office, Thailand
2
Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand above 5. Only 3% of the total population investigated
3
Khon Kaen University, Thailand
4
Deutsche Gesellschaft fur Technische Zusammenarbeit (GTS),
had a LDL-HDL ratio above that value. Since hyper-
Eschborn, Germany triglyceridaemia is also linked to the insulin resistant
5
Institute of Social Medicine and Medical Psychology, Free University
Berlin, Germany syndrome, it is concluded that, if the mortality of
coronary heart disease increases in future, then this
An investigation was undertaken in Northeast must be accounted probably more to the after-effects
Thailand, a countr y undergoing rapid health of the insulin-resistant syndrome than to the direct
transition, to find out whether there is a likelihood effect of an atherogenic lipid pattern. This view is
that the nutritional and lipid pattern of an adult supported by a high prevalence of impaired glucose
population in Northeast Thailand is related to tolerance (IGT) and non-insulin dependent diabetes
coronary heart disease in the same way as in western mellitus (NIDDM) in the population under survey.
countries. In a cross-sectional study, the body mass Preventive measures in the area should concentrate
index (BMI) and the waist-hip ratio as well as the among others on reducing overnutrition, especially
important plasma lipids were determined. The among women, and increasing physical activity and
nutritional status and the lipid profile of the predomi- screening for NIDDM.
nantly middle-aged population is characterised by a
generally favourable nutritional status and lipid Published in : Internat J Vit Nutr Res 1998;68:196-202.
concentrations, where the distribution, indicated by
Songsak Petmitr1 , Somchai Pinlaor1, Ampai Thousungnoen1, sequencing. Results showed that point mutations at
Anant Koralak2, Panata Migasena1
these regions in K-ras oncogene were not present in
1
Department of Tropical Nutrition and Food Science, Faculty of
Tropical Medicine, Mahidol University, Rajvithi Road,
all the samples. One case harboured a p53 gene
Bangkok 10400, Thailand. mutation in codon 282 in exon 8, CGG (arginine) to
2
Pathology Division, National Cancer Institute, Rama VI Road,
Bangkok 10400, Thailand. TGG (tryptophane), but the mutation was not found
in other patient’s tissues with similar histological
Paraffin embedded tissues from twenty Thai features .
patients with intrahepatic cholangiocarcinomas were
studied for K-ras gene mutations at codon 12, 13 and Published in : Southeast Asian J Trop Med Public
61 and for p53 gene mutations in exon 5 to 8 using Health 1998; 29: 71-5.
polymerase chain reaction and thermal cycle
p53 GENE MUTATIONS IN NON-SMALL CELL LUNG CANCER FROM THAI PATIENTS