UNlVERSlTY OF CALlCUT

M.Sc. CHEMlSTRY (CCS PATTERN) SEMESTER lV

CH4EO8 BlOlNORGANlC AND ORGANOMETALLlC
CHEMlSTRY (Elective) (4 Credits)
Unit l: Bioinorganic Chemistry-l (9 h): Coordnaton stes n boogcay
mportant gands. Thermodynamc and knetc aspects of stabty.
Eectronc and geometrca structures of meta ons n boogy. Roe of
aka meta ons n boogca systems. Ionophores and passve
transport. Sodum pump and actve transport.
Unit ll: Bioinorganic Chemistry ll (9 h): Metao enzymes and eectron
carrer metao protens. Lews acd. Roe of Zn (II) and Mg (II) contanng
enzymes. Redox enzymes. Iron enzymes- cytochrome P-450, cataase,
peroxdase.
Copper enzymes- Oxdase, superoxde dsmutase vtamn B
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and Co-
enzyme.
Unit lll: Bioinorganic Chemistry lll (9 h): Transport of oxygen by Heme
protens- hemogobn and myogobn. Non heme oxygen carrers,
hemerythrn hemocyann and hemovanadns.
Structure and functon of protens n eectron transport process,
cytochromes and ron suphur protens.
Unit lV: Bioinorganic Chemistry lV (9 h): Boenergetcs and ATP cyce,
gucose storage, chorophy photosystem I and II. Ntrogenases-
Boogca ntrogen fxaton, other ntrogenases, mode systems.
Meta defcency and dseases, toxc effects of metas, meta compexes
used for dagnoss and chemotherapy, Antcancer drugs.
References:
1. S.L. Lppard and |.M. Berry, Prncpes of Bonorganc Chemstry,
2.
3.
4.
5.
6.
7.
Unversty Scence Books, Caforna, 1997.
D.E. Fent on, Bocoordnaton Chemstry, Oxford Unverst y Press,
Oxford, 1995.
Ivam Bertn, Harry B Gray, Stephen. |. Lppard and |oan Severstone,
Vaentne, Bonorganc Chemstry, Unversty Scence Books, 1994.
R.W. Hay, Bonorganc Chemstry, Es Horwoord, 1984.
D.F. Shrver, P.W. Atkns and C.H. Langford, Inorganc Chemstry,
ELBS, 1990.
|.E. Huheey, E.A. Kerter and R.L. Keter, Inorganc Chemstry,
Prncpes Structure and Reactvty, Pearson, 2001.
F.A. Cotton and G. Wknson, C.A Muro and M. Bochmann, Advanced
Inorganc Chemstry, |ohn Wey & Sons, 1999.