M.Sc.

Biotechnology (Previous) Model Test Paper Virology &Immunology

Time: 2 Hrs. Note: Q.1 is compulsory. Answer five questions in all. Q1. Answer the following accordingly (in short): A) Viriods consist of: 1. ssRNA which is circular 2. ssRNA which is linear 3. ssDNA which is circular 4. ssDNA which is linear B) Name of David Baltimore is associated with 1. Virusoids 2. Viriods 2. Classification of Bacteria 4. Classification of viruses C) Define Attenuation D) Toxoids are described as ___________ E) Plant virus infect 1. Only Plants 3. Plants and Bacteria 2. Plants and animals 4. Plants and man (10*2=20) MM: 100

F) In which of the following Horse radish peroxidase is used? 1. Precipitation 2. Agglutination 3. ELISA 4. Radioimmunoassay G) Burst size of T-even phages is 200 T/F H) What are indicator plants? I) Cynophages were discovered by ____________ J) Antibodies that aggregate soluble antigens are called_____________ Q2. Q3. Q4. Q5. Q6. Q7. Q8. Explain (10*2=20) a) Vaccines b) Innate and acquired immunity What is hypersensitivity? Give its types and explain them in brief. (10) Define cancer. Explain the cancer tumor immunology. (10) What are auto antibodies? Explain its various types. (10) Explain the various cells and organs of the immune system. (10) Write structure, symptoms and disease caused transmission and control of either TMV or Cauliflower Mosaic Virus. (10) Write notes on: a) Segmented Genome b) Cryptogram Give an account of cultivation of viruses in animal cell culture. What are the advantages of this method when compared to cultivation of viruses in experimental animals? (10)

Q9.