The Science Behind and Health Benefits of Nitric Oxide Supplement CircO2

Nitric oxide (NO), also called nitrogen oxide (and not to be confused with the anesthetic nitrous oxide), is a signaling molecule that plays an important role in many biological processes, including circulation and brain function. Three men won the Nobel Prize in Physiology in 1998 for their discovery of how nitric oxide affects the cardiovascular system1, and researchers at MIT have since discovered how nitric oxide is most effectively supplemented in the diet. Nitric Oxide Improves Circulation, Brain Function, Bone DensityEven Sex Drive Nitric oxide has been found to support a healthy heart and circulation, boost brain power and even improve sexual health2. Nitric oxide protects organs such as the liver from ischemia, a restriction in blood supply to tissues. NO has also been found to reduce triglycerides in certain patients3 , and a study published by the Journal of the American Medical Association (JAMA) found a link between nitric oxide and bone health4. The JAMA study compared two groups of womenone who took a nitric oxide supplement, and one who took a placeboand found that the group of women who took the NO supplement had improved bone density. Conversely, the group who took the placebo actually lost bone density in their hips. Reduced bone density in the hips is especially troublesome, as this increases the chance of a hip fracture, a common cause of disability and even death in older individuals. MIT Researchers Find Nitric Oxide Supplements in Pill Form Ineffective Given the multiple benefits of nitric oxide, the question is how to effectively supplement NO in the diet. Researchers at MIT discovered that most nitric oxide is actually produced in the mouth when the nutrients in food interact with natural bacteria found in the saliva5. These findings led the researchers to conclude that taking nitric oxide via pill formthe most common means of administrationis much less effective, if not ineffective. The Most Effective Way to Take a Nitric Oxide Supplement People are commonly advised to take L-arginine to boost nitric oxide, but it is difficult for the body to convert L-arginine to nitric oxide, especially for those over age 40. As people age it becomes more difficult for the body to produce nitric oxide6. Additionally, taking nitric oxide in pill, tablet or powder form is almost completely ineffectiverecall the MIT researchers who discovered that nitric oxide is produced in the mouth when food nutrients react with bacteria in the saliva. The most effective way to boost nitric oxide is via a dissolvable lozenge such as CircO2, the dissolvable lozenge developed by the nutrition professionals at Advanced Bionutritionals. Nitric oxide lozenges interact with the saliva and bacteria in your mouth, converting the nutrients in the lozenge into nitric oxide. Unlike a pill, tablet or powder, in lozenge form your body gets a boost of NO with every swallow.

Summary Nitric oxide plays a critical role in several biological processes in the body and has been found to improve circulation and brain function, among other benefits. The most effective way to take nitric oxide is through a dissolvable lozenge, such as CircO2, distributed by Advanced Bionutritionals. Company Bio Advanced Bionutritionals is a cutting edge line of nutraceuticals. We work closely with our suppliers and our manufacturers to ensure that your supplements are made with fresh, quality ingredients following good manufacturing practice guidelines. Our highly qualified team is always researching new and better ingredients to ensure safe, effective health solutions for you. Visit our website at http://www.advancedbionutritionals.com or call us toll free at 1-800-791-3395. Sources: 1. http://www.nobelprize.org/nobel_prizes/medicine/laureates/1998/index.html 2. http://www.advancedbionutritionals.com/Products/CircO2.htm 3. http://www.nrjournal.com/article/S0271-5317%2811%2900046-7/abstract 4. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3606948/ 5. http://www.sciencedirect.com/science/article/pii/S0015626476800065 6. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3018552/