1)thefollowingstatementsarecorrectforcervixcancer: a)Cervicalcancerisasexuallytransmitteddisease. b)Alcoholisconsideredasariskfactor c)MostfrequenttypeofHPV. Answer asexuallytransmitteddisease. up7080%indevelopingcountries HPV16&18,herpessimplexHSV 2)Amongtheetiologiesofcervixcancer,itis a)Lateageatfirstintercourse. b)Lownumberofsexualpartners c)Highsocioeconomicstatus d)Highriskmalepartner Answer earlyageatfirstintercourse.

numberofsexualpartners Lowersocioeconomicstatus Highriskmalepartner 3)cervixcancerstartsfrom: a)Basallayer. Answer squamocolumnarjunction 4)forthenaturalhistoryofcervixcancerthecorrectis: a)metaplasia Answer dysplasia>insituCa>earlyinvasiveCa Long(1020yrs)evolutionasymptomatic 5)themostfrequentpathologicaltypeofcervixcanceris: Answer squamouscellcarcinoma90% 6)astage3BFIGOcancerinvolvethe:reviewstaging(breastandcervix) a)Cervixandparametriumuptopelvicwall. 7)earlysignsofcervicalcarcinomaare: Answer Smellyvaginaldischarge Postcoitalvaginalbleeding. Postmenopausal

bleedingirregularmensesover10days 8)mostacceptedtherapeuticapproachforstage2Bcervix: Answer Radiotherapy+CDDP(cisP)followedwithsurgery 9)whichofthefollowingstatementsarecorrectforuterinecorpustumours: Answer itisprimarilyadiseaseofpostmenopausalwomen Increaseincidenceinwesternworld

10)amongtheriskfactorsofuterinecorpuscancer: Answer a)tamoxifen b)obesity 40s,Fat,multiparous,hormonalfactors 11)whichofthefollowingspathologytypehaveaggressivebehaviour a)papillaryserouscancer b)clearcellcancer(vaginalcancerinyoungwomen,OTCpilltakenbymother) 12)serousinvolvementischaracteristicfor: a)uterinecorpus.SerousadenocysticCaoftheovaries Caoftheovariespresents50%serousinvolvement,screwtheuterinecorpus 13)themostimportantsignsofuterinecancer: Answer enlargeduterus Postmenopausalvaginalbleeding 14)headandneckcancerhavethefollowingdistribution: Answerbimodaldistributioninadolescence+youngadultsvs.5070yr BIMODAL 15)nasopharynxcancerappearmostfrequentlyat: Answer a)youngage.age:bimodaldistributioninadolescence+youngadultsvs.5070yr

16)intheetiologyofheadandneckcancer,itisconsidered: Answer a.EBV, b.HPV

17)thefollowingstatementisfrequentlyforthehistologicalfeaturesonheadandneck cancer: a)mostfrequent.=Carcinomawith80% b)Correct. Answer *carcinoma80% *lymphoma1520% *adenoCarare:salivaryglands *sarcomarare:children 18)forheadandneckcancerthefailureispredominantly: Answer a)locoregional. 19)anypalpable: 20)glotticcancerhavethefollowingcharacteristics: Answer NolymphaticspreadNotescarcityoflymphaticsatlevelofglottis

21)salivaryglandtumours: a)undifferentiated. bothsexesequallyaffected anyage,median4050yr.. 80%inparotidgland:2/3benign 10%submandibulargl:50%benign 10%minorsalivarygl:Malignant ClinicalPresentation: swelling:rapidgrowth,localpain,facialpalsy, structures,trismus,palpablecervicalLN submandibularlesions:painless,firmmass minorsalivarylesions:nodularsurface hard palate+++

tenderness,attachmenttosurrounding

growth,submucosal,withoutulceration,

22)thegoldstandardforlocallyadvancedheadandneckcancers: a)chemotherapyandradiotherapy. 23)neoadjuvantchemotherapyforheadandneckcancerhasthefollowing: a)toshrink. 24)thechemotherapyschemeforepidermal.theMabs

25)PF=cisplatin+5FU(chemotherapyforheadandneckcancer)containthefollowing drugs:CFM??? Methotrexate,Cisplatin,Carboplatin,Oxaliplatin,Paclitaxel,Docetaxel,Irinotecan,Gemcitabine ,Gefitinib(toconfirm)

26)Theaimofposttherapeuticarethefollowingfortheheadandneckcancer: Prevent:local/locoregionalrecurrence metastases:lung,bone 2ndprimaryT:respiratory&urinaryepithelium comorbidities:cardiovascular rehabilitation:nutritional,speech prevention!!!!!

OncologyTEST(A)
1.Thespreadofsofttissuesarcomaischaracterizedby: a.lymphaticextension b.localextensionalongtissueplanesrespectinganatomicboundaries c.haematogenousspreadafterfiveyears d.lungmetastases e.presenceoftruecapsulearoundthetumor 2.WhichofthefollowingfeaturesarecharacteristicforKaposissarcoma a.increasedincidenceinAfrica b.decreasedincidenceinAIDSdisease c.lackofefficiencyoflocalradiotherapy d.worseoutcomeinAIDsrelatedcases

e.purplishnodulesofthelowerextremity 3.Whichofthefollowingfeaturesarecharacteristicformalignantbonetumors: a.sharplyoutlinedscleroticborder b.presenceofsofttissueextension c.motheatendestroyedareas d.solid,uninterruptedperiostealreaction e.extensioninthebonemarrowspace 4.Whichofthefollowingtumorsareincludedintheclassificationofbonetumors: a.fibrosarcoma b.Kaposissarcoma c.Parostealosteogenicsarcoma d.Rhabdomyosarcoma 5.Thefirsttreatmentchoiceforlocalized(T2)kidneycanceris a.chemotherapy(weeklyvinblastine) b.radiotherapy4050Gy c.nephrectomy+lymphadenectomy d.immunotherapy 6.Yourtreatmentoptionforearlystageprostatecanceris: a.radicalprostatectomy b.combinedtreatment(radiochemotherapy) c.radiotherapyalone d.chemotherapyalone e.debulkingsurgery 7.Yourtreatmentoptionsforseminomais a.radicalorchiectomybyscrotalapproach b.radicalorchiectomybyinguinalapproach c.radiotherapy2040Gy d.radiotherapy4050Gy e.anthracyclinebasedchemotherapy f.cisplatinbasedchemotherapy g.hormonalmanipulation 8.Thecarcinomaofthepenisis: a.squamouscellcarcinoma b.adenocarcinoma c.transitionalcellcarcinoma d.mucinouscarcinoma e.allofthesetypes

9.Whichofthefollowingstatementsarecorrect: a.hypopharynxcanceristhemostlethalHandNcancer b.theanatomicsubdivisionofthelarynxis:supraglotticlarynx,glotticlarynx,subglotticlarynx c.attheleveloftheglottisthereareseverallymphaticsendingintheanteriorjugularchain d.Unilateralenlargedcervicalmasscanbetheonlysignofahypopharynxtumor e.2/3oftheparotidglandtumorsaremalignant 10.YourtreatmentoptionforT2N0M0supraglotticlarynxcanceris: a.Radiotherapy b.Cordectomy c.Chemotherapy d.Concurrentchemoandradiotherapy e.Totallaryngectomy 11.Inlarynxcancercombinedmodalitytreatment(chemo+radiotherapy)isindicated for: a.stageIcasesindifferentoftheperformancestatus b.forpatientwithlocallyadvanceddiseasewithgoodperformancestatus c.forallthepatientswithpoorperformancestatus d.forallcasesindifferentofperformancestatusandstage 12.Forheadandneckcancerthestandardchemotherapyis: a.Etoposide+cisplatin b.Cisplatin+5FU c.Epidoxorubicin+cyclophosphamide d.Taxanebasedmonotherapy 13.Thenaturalhistoryofcervicalcancerischaracterizedby: a.Infieldcancerogenesis b.Evolutionthroughdysplasiainsitucancerearlyinvasivecancer c.Immediateonsetofdistantmetastases d.Longasymptomaticperiod 14.Whichofthefollowingstatementsarecorrect: a.cervicalcancerextendsthroughthelymphaticstoinguinallymphnodes b.instageIcervicalcancerthepelviclymphnodesareinvolvedin15%ofthecases c.themostfrequentmetastaticsiteforcervicalcanceristheliver d.instageIIIcervicalcancertheparaaorticlymphnodescanbeinvolvedalmostin30%ofthe cases e.alloftheabovemotionedstatementsarecorrect

15.ForstageIIB(bulkyover4cm)cervicalcancerthegoldenstandardfortreatmentis a.chemotherapyfollowedbyradiotherapy b.concomitantchemoradiotherapyfollowedbysurgeryiflocalresponsewarrants c.surgeryfollowedbychemotherapyandsequentialradiotherapy 16.YouareaGP.Yourpatientwasdiagnosedwithmicroinvasivecervicalcancer.You shouldreferyourpatientto: a.surgeon(simplehysterectomy) b.radiotherapist c.medicaloncologist becauseyourtreatmentoptionis:simplehysterectomyorconebiopsy

17.Whichofthefollowingtechniquesareusedforthediagnosisofuterinecorpus cancer: a.Fractionateddilatationandcurettage b.gynecologicalexamination c.suctioncurettage d.conebiopsy e.tumormarkerCA125 18.Thenaturalhistoryofovariancancerisnotcharacterizedbythefollowingfeatures: a.bilateralovarianinvolvement b.lackofomentalinvolvement c.lackofparaaorticlymphnodeinvolvement d.presenceofsupradiaphragmaticseeding 19.Whichlesionareprecancerousfortheoesophagus a.PlummerVinsonsyndrome b.Achalasia c.Barrett'soesophagus d.Zenkersdiverticulum e.Alloftheabove 20.Latestageleftsidecoloncancerischaracterizedby: a.Anemia b.Constipationordiarrhoea c.Vagueabdominalpain d.Obstructivesymptom e.Abdominalcolickypain

SisterMaryperiumbilicalnode Irishnodulenodeleftanterioraxillarynode VirchowTrosierleftsupraclavicularnode BlumershelfnoduletumormassintheculdesacpalpableatDRE 22.Forthefollowingtumormarkersfindthetumoralsite: CEA Colorectal PSA prostate CA125 ovary Ca190 pancreas Ca153 breast 23.Indicatethecorrectsentence: a.Theaimofbreastcancerscreeningistodetectallbreastcancers b.Breastcancerscreeningincludeallwomenbetween3070years????? c.Thebesttoolforbreastcancerscreeningisphysicalexamination d.Screeningmeansearlydetectionofthedisease e.Mammographicscreeningdetectslesion<lcmandisefficientoverage40. 24.Theoptimaldoseforosteolyticmetastasesofthelumbarspineis: a.2030Gy b.4550Gy c.6070Gy 25.TreatmentoptionsforT4c(fixed)locallyadvancedbreastcancerare: a.Chemotherapy b.Surgery(wouldbetrueifoperable,butislocallyadvancedoperable?) c.Radiotherapy d.Hormonaltherapy 26.Whichdrugsareusedforhormonaltherapyofbreastcancer: a.Flutamideusedforprostatecancer b.Tamoxifen c.Megestrolacetatenotmentionedinhernotes d.Aminoglutethimidenotmentionedinhernotes e.Allofthisdrugs 27.Thedistinctivefeaturesalsmallcelllungcancerarethefollowing: a.Islesssensitivetochemotherapy b.Betterprognosis

c.Frequentmetastasestothebrain,liver,bone,softtissue d.Itisoftenmetastaticatpresentation e.Allthesefeaturesarepresent 28.Prognosticfactorsoflungcancer: a.LDH b.Tumorstage c.Performancestatusandweightloss d.Numberofsmokingyears e.Responsetochemotherapy 29.Thetermofprevalenceincancerepidemiologyindicates: a.Noofdeathregisteredinagivenpopulation,stand ardizedinadeterminedperiodoftime b.Noofcancercases(withorwithoutdisease)inagivenperiodoftimeforaspecificpopulation c.Noofregisterednewcancercasesinagivenpopulation,standardizedinadeterminedperiod oftime 30.Theuseofbetelispresentinthehistoryof: a.Liptumor b.Oralcavitytumor c.Larynxtumor d.Alloftheabovementioned 31.Cancerfamiliesarecharacterizedby: a.onsetofdiseaseatolderage b.multipleprimarytumors c.morefrequentunilateraltumors d.positivefamilialhistory e.lackofassociationwithcongenitaldefectsandmalformations

OncologyTEST(B)
1.Forheadandneckcancerthestandardchemotherapyis:??? a.Etoposide+cisplatin b.Cisplatin+5FU c.Epidoxorubicin+cyclophosphamide d.Taxanebasedmonotherapy

2.ForstageIIB(bulkyover4cm)cervicalcancerthegoldenstandardfortreatmentis a.chemotherapyfollowedbyradiotherapy b.concomitantchemoradiotherapyfollowedbysurgeryiflocalresponsewarrants c.surgeryfollowedbychemotherapyandsecventionalradiotherapy 3.Yourtreatmentoptionforearlystageprostatecanceris: a.radicalprostatectomy b.combinedtreatment(radiochemotherapy) c.radiotherapyalone d.chemotherapyalone e.debulkingsurgery 4.Yourtreatmentoptionsforseminomais a.radicalorchiectomybyscrotalapproach b.radicalorchiectomybyinguinalapproach c.radiotherapy2040Gy d.radiotherapy4050Gy e.anthracyclinebasedchemotherapy f.cisplatinbasedchemotherapy g.hormonalmanipulation 5.Thefirsttreatmentchoiceforlocalized(T2)kidneycanceris a.chemotherapy(weeklyvinblastine) b.radiotherapy4050Gy c.nephrectomy+lymphadenectomy d.immunotherapy 6.Thecarcinomaofthepenisis: a.squamouscellcarcinoma b.adenocarcinoma c.transitionalcellcarcinoma d.mucinouscarcinoma e.allofthesetypes 7.Thespreadofsofttissuesarcomaischaracterizedby: a.lymphaticextension b.localextensionalongtissueplanesrespectinganatomicboundaries c.haematogenousspreadafterfiveyears(90%inthefirst2years) d.lungmetastases e.presenceoftruecapsulearoundthetumor(nope) 8.Whichofthefollowingstatementsarecorrect: a.hypopharynxcanceristhemostlethalHandNcancer

b.theanatomicsubdivisionofthelarynxis:supraglotticlarynx,glotticlarynx,subglotticlarynx c.attheleveloftheglottisthereareseverallymphaticsendingintheanteriorjugularchain Lymphaticsofendolarynx.Notescarcityoflymphaticsatlevelofglottis. d.Unilateralenlargedcervicalmasscanbetheonlysignofahypopharynxtumor e.2/3oftheparotidglandtumorsaremalignant(2/3benign) 9.Whichofthefollowingtumorsareincludedintheclassificationofbonetumors: a.fibrosarcoma b.Kaposissarcoma c.Parostealosteogenicsarcoma d.Rhabdomyosarcoma 10.YourtreatmentoptionforT2N0M0supragloticlarynxcanceris: a.Radiotherapy b.Cordectomy c.Chemotherapy d.Concurrentchemoandradiotherapy e.Totallaryngectomy 11.Inlarynxcancercombinedmodalitytreatment(chemo+radiotherapy)isindicated for: a.stageIcasesindifferentoftheperformancestatus b.forpatientwithlocallyadvanceddiseasewithgoodperformancestatus c.forallthepatientswithpoorperformancestatusforpatientstheyaretechnicallyresectable butmedicallyarenotfit d.forallcasesindifferentofperformancestatusandstage 12.Thenaturalhistoryofcervicalcancerischaracterizedby: a.Infieldcancerogenesis b.Evolutionthroughdysplasiainsitucancerearlyinvasivecancer c.Immediateonsetofdistantmetastases d.Longasymptomaticperiod 13.Whichofthefollowingfeaturesarecharacteristicformalignantbonetumors: a.sharplyoutlinedscleroticborder b.presenceofsofttissueextension c.motheatendestroyedareas d.solid,uninterruptedperiostealreaction e.extensioninthebonemarrowspace 14.Whichofthefollowingstatementsarecorrect:

a.cervicalcancerextendsthroughthelymphaticstoinguinallymphnodes b.instageIcervicalcancerthepelviclymphnodesareinvolvedin15%ofthecases c.themostfrequentmetastaticsiteforcervicalcanceristheliver d.instageIIIcervicalcancertheparaaorticlymphnodescanbeinvolvedalmostin30%ofthe cases e.alloftheabovemotionedstatementsarecorrect

15.Whichofthefollowingtechniquesareusedforthediagnosesofuterinecorpus cancer: a.Fractionateddilatationandcurettage b.gynecologicalexamination c.suctioncurettage d.conebiopsy(nope,thatsforcervix) e.tumormarkerCA125

16.YouareaGP.Yourpatientwasdiagnosedwithmicroinvasivecervicalcancer.You shouldreferyourpatientto: a.surgeon b.radiotherapist c.medicaloncologist becauseyourtreatmentoptionis:simplehysterectomyorconebiopsy(inselectedwomen) 17.ThenaturalhistoryofovariancancerisNOTcharacterizedbythefollowingfeatures: a.bilateralovarianinvolvement b.lackofomentalinvolvement c.lackofparaaorticlymphnodeinvolvement d.presenceofsupradiaphragmaticseeding 18.Whichlesionareprecancerousfortheoesophagus a.PlummerVinsonsyndrome b.Achalasia c.Barrett'soesophagus d.Zenkersdiverticulum e.Alloftheabove 19.WhichofthefollowingfeaturesarecharacteristicforKaposissarcoma a.increasedincidenceinAfrica b.decreasedincidenceinAIDSdisease c.lackofefficiencyoflocalradiotherapy d.worseoutcomeinAIDsrelatedcases e.purplishnodulesofthelowerextremity

20.Whatis? SisterMarynoduletumormassintheculdesacpalpableatDRE Irishnoduleleftsupraclavicularnode VirchowTrosiernodeleftanterioraxillarynode Blumershelfperiumbilicalnode

21.Forthefollowingtumormarkersfindthetumoralsite: CEApancreas PSAbreast CA125Colorectal Ca190prostate Ca153ovary

ca153forbreastcancer ceaisforcolorectalaswellasbreastcancer (confirmall) 22.Indicatethecorrectsentence: a.Theaimofbreastcancerscreeningistodetectallbreastcancers b.Breastcancerscreeningincludeallwomenbetween3070years c.Thebesttoolforbreastcancerscreeningisphysicalexamination d.Screeningmeansearlydetectionofthedisease e.Mammographicscreeningdetectslesion<lcmandisefficientoverage40. 23.Theoptimaldoseforosteolyticmetastasesofthelumbarspineis: a.2030Gy b.4550Gy c.6070Gy 24.TreatmentoptionsforT4c(fixed)locallyadvancedbreastcancerare: a.Chemotherapy b.Surgery(islocallyadvancedoperable??) c.Radiotherapy d.Hormonaltherapy 25.Whichdrugsareusedforhormonaltherapyofbreastcancer: a.FlutamideprostateK b.Tamoxifen c.MegestrolacetateTbutdidntmentionit d.AminoglutethimideTbutdidntmentionit

e.Allofthisdrugs 26.Thedistinctivefeaturesalsmallcelllungcancerarethefollowing: a.Islesssensitivetochemotherapy b.Betterprognosis c.Frequentmetastasestothebrain,liver,bone,softtissue d.Itisoftenmetastaticatpresentation e.Allthesefeaturesarepresent

27.Prognosticfactorsoflungcancer: a.LDH b.Tumorstage c.Performancestatusandweightloss d.Numberofsmokingyears e.Responsetochemotherapy 28.Thetermofprevalenceincancerepidemiologyindicates: a.Noofdeathregisteredinagivenpopulation,standardizedinadeterminedperiodoftime b.Noofcancercases(withorwithoutdisease)inagivenperiodoftimeforaspecificpopulation c.Noofregisterednewcancercasesinagivenpopulation,standardizedinadeterminedperiod oftime 29.Theuseofbetelispresentinthehistoryof: a.Liptumor b.Oralcavitytumor c.Larynxtumor d.Alloftheabovementioned 30.Cancerfamiliesarecharacterizedby: a.onsetofdiseaseatolderage b.multipleprimarytumors c.morefrequentunilateraltumors d.positivefamilialhistory d.lackofassociationwithcongenitaldefectsandmalformations 31.Latestageleftsidecoloncancerischaracterizedby: a.Anemia b.Constipationordiarrhoea c.Vagueabdominalpain d.Obstructivesymptom e.Abdominalcolickypain

2.Afterchemotherapywhichsideeffectsappear? anemia,alopecia,localskinreaction,thrombocytopenia,nauseaandvomiting 3.thesmallestdetectabletumoris: 1g,1cm=1ml 4.Whichofthefollowingstatementsiscorrectfordistantmetastasis: a.metastasistumorwithotherhistologyascomparedtoprimarytumor, b.metastasisisadistincttumorgrowthseparatedfromtheprimarytumor c.metastasisreproducesthemorphologicalfunctionsand.oftheprimarytumorbutnot necessaryaperfectidentity ****correctalltheanswersa,b,c Surgerycanbeusedinoncologyfor: radicaltreatmentoftheprimarytumors,conservativetreatment,metastasisexcision,palliation, reconstruction.allofthem(arecorrectanswers) Completeresponsecanbedefinedas(fromthepractical) *completedisappearanceofmalignantlesionsatleast4weeksaftertreatment, acutetreatmentrelatedreactionsappearafterradiotherapy 5.Whichofthefollowingstatementsarecorrectforradiationtherapyincaseofcervix cancer: a.Radiationtherapyisageneraltreatment b.Radiationtherapyisalocaltreatment. c.Radiationtherapyisageneralandlocaltreatment d.Brachytherapyisneverindicatedincaseofcervixcancer e.weuseacombinationofexternaltherapyandradiotherapy. Riskfactorsforbreastcancer? Personalhistory Earlymenarche<12

Latemenopause>50 Nullparityorfirstpregnancyover30 Lackofbreastfeeding Genetic Firstbreastgraderelativeswithbreastcancer Familiarcancersyndrome Lynch BRCA1andBRCA2genechanges Pathologic Proliferativbenignbreastdisease Lifestyle Abuse,smokingobesity

Thediagnostictriadforbreastcancerincludes? Physicalexaminationmammographybiopsy Confirmationofmalignancyisdoneby:BIOPSY Typesofstomachcancerare Riskfactorsforcervixcancer Earlyageofintercourse Numberofsexualpartners Smoking Lowersocioeconomicstatus Highriskmalepartner Othersexuallytransmitteddiseases Upto70%oftheU.S.populationisinfectedwithHPV

TheGoldenStandardforlocallyadvancedcervicalcanceris:Cisplatin+Radio Themostimportantclinicalsignforcorpusuterinecanceris? Postmenopausalvaginalbleeding 20.Themostimportantnegativesignofcancer:absenceofpain 21.AmongtheETIofcervixCAitisconsidered: D,e 22.b 23.d 24.b,c 25.a,b

26.a,b 27.Smallglotticcancer=>a)nolymphaticconnection 28.SVCsyndrome=>b)lungande)mediastinalmalignantlymphomas 29.Goldstandardforlocallyadvancedhead&neckCA:a)chemo+radio 30.Whatisthemostfrequentindicateddoseforpalliativeradiationtherapy?20Grey

Min11:56Whichofthefollowingstatementsarecorrect: a)riskoflungCAiscorrelatedtothedurationandquantityofsmoking b)abandoningsmokingafter510yearsdecreasestherisktothelevelofanonsmoker c)theriskoflungCAisonlyrelatedtotheDURATIONofsmoking d)theriskoflungCAisrelatedtoQUANTITYofsmoking Themostimportantriskfactorsforhead&neckCAare? a)SmokingandalcoholT b)Helicobacterpylori c)Inhalationofnickel d)lowintakeofvitaminE e)Alloftheabove WhichofthefollowingtreatmentscanbeindicatedforprostateCA?(stage??) a)Radicalprostatectomy b)Highdoseradiotherapy c)Interferontherapy d)Chemoonly e)Interferonplus?XYZ?therapy Correlationbetweentypeofinfectionanddisease: StomachHelicobacterpylori LiverHepatitisBHepatitisC CervicalHumanPapillomavirus LymphomaEpsteinBarr Smallestclinicallydetectabletumoris?1gor1cmor1ml Definitionofsubclinicaldisease Correctdefinitionofstagingprocess Pathologicalclassificationofthetumor Theprocessofestablishingtheanatomicextentofthetumorwiththeinclusionofthepatientina

groupforwhichthetreatmentandprognosisaresimilar *Thesametumorswiththesametumorresponse *Differenttumorswiththesametumorresponse *Otheranswersareobviouslystupid TreatmentcategoriesforbreastCA: a)OperablebreastCA b)MetastaticbreastCA c)LocallyadvancedbreastCA d)EasybreastCA e)ConservativelyoperablebreastCA A,b,c,e Min15:30Partialresponsedefinition(alsostablediseaseDEF) Decreaseoftumorvolumewithmorethan50%andnometastases lessthan20%=stable Majorityofrelapseappearsafter2years Chemotherapycanbegivenon a)AweeklybasisT b)EverythreeweeksT c)EverythreemonthsF d)TwiceadayF e)AlloftheaboveF RiskFactorsforbreastCAare a)FirstgraderelativewithbreastCAT b)PresenceofBRCA1&BRCA2T c)Latemenarcheover12F d)HormonereplacementtherapyT e)Obesity,substanceabuse,smokingF

Clinicalsignsofgravityattheleveloftheprimarybreasttumorsare: a)>5cmT b)ChestwallfixationT c)AverysmallsuperficialtumorF d)Asmalltumor<2cmF e)Involvementofskin,ulceration,erythemaT BreasttumorthatisclassifiedT2?

>2cmand<5cm RiskFactorforgastricCAincludes: a)DiethighinsaltandsmokedfoodsT b)InfectionwithhelicobacterpyloriT c)AlcoholandtobaccoF d)VillousadenomaF e)PreviousulcerT Forstages3&4stomachcancerisindicated: a)CombinedCT&RT=T b)RadicalsurgeryF c)NotreatmentF d)TargetedtherapyF ThefrequencyofcervicalCAishigherincaseof: a)HPV16&18T b)Therestoftheanswersareobviouslyincorrect Thegoldstandardforearlycervixcanceris: a)Surgery???=T b)PreoperativeCT c)RT=T d)CT&targetedtherapyF e)Alloftheabove Initiationisdefinedas a)ResultofgenotoxicmechanismsT b)duetochemicalsF c)virusesF d)+oxidativeradicalsF e)sciencedoesntknowthecorrectanswerF

CervixCAstartsfrom: a)thesquamocolumnarjunctionT Stage3bfigoCA(cervixCA)includes: a)cervixandparametrialinvolvementuptothepelvicwallT Themostacceptedtherapeuticapproachforstage2bcervixcanceris: a)RT

b)CDDP=cisplatin c)RT&CDDP Whichofthefollowingpathologicaltypeshasaggressivebehavior: a)BCCF b)SimpleadenoCAF c)ClearcellCAT d)PapillaryserousCAT e)UndifferentiatedCAT NasopharynxCAappearsfrequentlyin: a)Onlyinyoungadults b)Veryoldages c)sporadicaloldages d)Bimodaldistribution=>T e)Adolescentandyoungadults Thefollowinghistologyischaracteristicforhead&neckCA: answer nonsmallcell:SquamouscellCA,adenocarcinoma,undifferentiatedlargecell smallcellcarcinoma SmallcelllungCAgivesmetastasisto: a)Brain=>T b)Uterus c)Adrenalgland=>T d)Uppercervicallymphnodes PFchemotherapy?Isindicated PFchemotherapy?Containsthefollowingdrugs: a)Prednisone b)5Fluorouracil(5FU) c)Cisplatinium&5FU=>T d)XYZ e)XZY

Neoadjuvanttherapyforhead&neckCAhasthefollowingaim: a)Toshrinkthetumor=>T b)Toreducetheagespecificmortality c)Morbidity d)Todecreasethetreatmentrelatedtoxicity e)Tomakepossibleorganpreservation=>T

WhatisthemostfrequentlyindicateddoseforpostoperativeRT: 5060gy

Labquestion:
1.Givethedefinitionofpartialresponse bidimensionalreductionofthetumorbymorethan50% 2.Def.performanceindex2 patientinbedfor<50%ofthetime 3.Mainsideeffectofradiationtherapy Nausea,vomiting,alopecia 4.Describethetherapeuticpossibilitiesforthebreastcancer surgery,radiotherapy,localtherapy,chemotherapy,hormonaltherapy,systemictherapy 5.Givethedefinitionofthesolicdisease 6.Givethedefinitionofperformanceindex3 patientinbedfor>50%ofthetime 7.Sideeffectsofchemotherapy leukopenia,thrombocytopenia,stomatitis,nausea,vomiting,pigmentation,cardiacfailure 8.Therapeuticpossibilitiesforcervicalcancer cryotherapy,electrocautery,excision,lasertherapy,conebiopsy,simpleandradical hysterectomy,radiotherapy PASTELABANSWERSRIGHTHERE=)

Stage1 Cervicalcarcinomaconfinedto uterus(extensiontocorpusshould bedisregarded)

IICervicalcarcinomainvadesbeyond

uterusbutnottopelvicwallorto lowerthirdofvagina IIATumorwithoutparametrialinvasion IIBTumorwithparametrialinvasion IIITumorextendstopelvicwalland/ orinvolveslowerthirdofvagina, and/orcauseshydronephrosisor nonfunctioningkidney IVATumorinvadesmucosaofbladderor rectum,and/orextendsbeyondtrue pelvis(bullousedemaisnotsufficienttoclassifyatumorasT4)