Brand Name: Chloromycetin

Generic Name: Chloramphenicol

Indication: External Ear Canal infection
Drug Classification: Antibiotic (Macrolides)
Mechanism of Action: Inhibits or destroys bacteria in ear canal.
Dosage: Adults and Children: 2-3 drops in ear canal
Special Precaution: Renal or hepatic impairment, G6PD deficiency, acute
intermittent porphyria. Premature and full term infants
Pregnancy Risk Category: C
Adverse Reaction: EENT: ear itching or burning
GU: hemoglobinuria
Hematologic: bone marrow depression, bone marrow hypoplasia, aplastic
anemia
Metabolic: Lactic acidosis
Skin: pruritis, urticaria
Other: overgrowth or non susceptible organisms
Contraindications: Contraindicated in patients hypersensitive to drug or its
components and in those with perforated eardrum.
Form: Otic solution: 0.5 %
Nursing Responsibility:
 Obtain history of drug use and reactions.
 Monitor patient for signs and symptoms of super infection. Avoid
prolonged use.
 Reculture persistent drainage
 Monitor patient for sore throat ( early sign of toxicity)
 Alert: Don’t confuse Chloromycetin with chlorambucil