FC Derm (SA) Part I

THE COLLEGES OF MEDICINE OF SOUTH AFRICA

Incorporated Association not for gain Reg No 1955/000003/08

Part I Examination for the Fellowship of the College of Dermatologists of South Africa 6 September 2011 Paper 1 (3 hours)
All questions to be answered. Each question to be answered in a separate book (or books if more than one is required for the one answer)

Describe a) The factors affecting the function of the pilosebaceous follicle. b) The role of the Langerhans cell in the skin. c) Communication between keratinocytes.

(12) (6) (7) [25]

Discuss the various morphological types of granulomatous inflammation and mention the most likely etiological agents that you can associate with each type respectively. Refer to relevant ancillary pathology tests that can be done to demonstrate etiological agents in tissue sections. [25] a) b) Draw a diagrammatic representation of the different sensory receptors in the skin. (15) Discuss the innervation of the skin with specific reference to the regional variations. (10) [25]

Discuss a) The carcinogenic role of human papilloma virus. (13) b) The etiopathogenesis and morphology of type III hypersensitivity reaction. (12) [25]

FC Derm (SA) Part I

THE COLLEGES OF MEDICINE OF SOUTH AFRICA

Incorporated Association not for gain Reg No 1955/000003/08

Part I Examination for the Fellowship of the College of Dermatologists of South Africa 7 September 2011 Paper 2 (3 hours)
All questions are to be answered. Each question to be answered in a separate book (or books if more than one is required for the one answer)

a) b) c)

Write notes on the pathogenesis of oedema. Discuss reperfusion injury. Tabulate the differences between dry and wet gangrene.

(10) (10) (5) [25]

Discuss a) The role of TNF- in inflammation. b) Epigenetics and cancer. c) Apoptosis in HIV.

(10) (10) (5) [25] (12)

a)

Atopic eczema is a disorder of barrier function. Discuss this statement.

Write short notes on b) Neuropeptides in the skin. c) Functions of the endothelial cell.

(7) (6) [25]

a) b) c)

Draw a cross section of the nail unit. (10) Discuss the blood supply of the skin with specific reference to the finger. (10) List the common tumours affecting the finger tip unit anatomically. (5) [25]

FC Derm (SA) Part I

THE COLLEGES OF MEDICINE OF SOUTH AFRICA

Incorporated Association not for gain Reg No 1955/000003/08

Part I Examination for the Fellowship of the College of Dermatologists of South Africa 8 September 2011 Paper 3 (3 hours)

All questions are to be answered. Each question to be answered in a separate book (or books if more than one is required for the one answer)

Give a full account of a) Collagen in the skin, including histology, ultrastructure and synthesis. (15) b) Stem cells in the skin, including their role in normal epidermal structure and in wound healing. (10) [25] a) Discuss the aetiology of auto-immune diseases. (10)

Write notes on b) The pathology of terminally ill patients that are confined to bed. c) Mixed tumours.

(10) (5) [25]

Write notes on a) Control of apoptosis. b) IL-22 and IL-17.

(15) (10) [25]

Write short notes on the following a) Melanosome transfer into keratinocytes. b) Reverse-transcriptase PCR. c) Adipocytes. d) Desmosomes. e) Stages of the hair cycle.

(5) (5) (5) (5) (5) [25]