Beruflich Dokumente
Kultur Dokumente
, Advanced Biohealing
Westport, CT, USA; OrCell
, Ortec
International Inc., New York, NY, USA),
autologous cell-containing (Hyalograft
3D,
Fidia Advanced BioPolymers, Abano Terme,
Italy; Laserskin
, CellTran Ltd.,
Shefeld, UK), and acellular (OASIS
, Cook
Biotech, West Lafayette, IN, USA;
GRAFTJACKET
, LifeCell
Corporation, Branchburg, NJ, USA) matrices.
The rst two types of matrix contain living cells,
such as keratinocytes or broblasts, in a matrix,
while acellular matrices are free of cells and act
by releasing growth factors to stimulate
neovascularization and wound healing.
Accumulating evidence shows that
bioengineered skin substitutes may be a
promising therapeutic adjunct therapy to the
standard wound care for the management of
noninfected diabetic foot ulcers. Nevertheless,
more studies need to be conducted in the future
in order to conrm these results [6369].
Extracellular Matrix Proteins
Hyaff