Indicate the inhaled anaesthetic, which reduces arterial pressure and heart rate.

Answer

A. Nitrous oxide

B. Desflurane

C. Halothane

D. Isoflurane
Restlessness, anxiety, orthostatic hypotension, generalised seizures, severe tremor, vivid
hallucination and psychosis are possibe symptoms of;
Answer

A. withdrawal

B. drug interactions between barbiturate and diazepam

C. tolerance

Which of the following is the antibiotic for cancer chemotherapy?
Answer

A. Etoposide

B. Doxorubicin

C. Cytarabine

D. Gentamycin
Which of the following anaesthesia may cause hepatic necrosis?
Answer

A. halothane

B. nitrous oxide

C. soveflurane

D. desflurane
Methotrexate : folic acid inhibitor
The mechanism of action of carbidopa is
Answer

A. stimulating the synthesis, release, or reuptake of dopamine

B. stimulating dopamine receptors

C. selective inhibition of catecol-O-methyltransferase

D. inhibition of dopa decarboxilase
Which of the following anxiolytics is preferred in patient with limited hepatic function?
Answer

A. diazepam

B. quazepam

C. chlordiazepoxide

D. buspirone
Which neurons are involved in parkinsonism?
Answer

A. dopaminergic neurons

B. GABAergic neurons

C. cholinergic neurons

D. all of the choice

Rational combination of anticancer drug is to
Answer

A. Provide stimulation of immune system

B. Provide synergism resulting from the use of anticancer drugs with different mechanisms
combination

C. Provide synergism resulting from the use of anticancer drugs with the same mechanisms
combination

D. Provide stimulation of cell proliferation
Indicate the antidepressant, which blocks the reuptake pumps for serotonin and norepinephrine
Answer

A. maprotiline

B. tranylcypromine

C. fluoxetine

D. Amitriptyline
Which of the following statements is correct?
Answer

A. MAO-A metabolises dopamine; MAO-B metabolise norepinephrine
and serotonin

B. MAO-B metabolises dopamine; MAO-A metabolise norepinephrine
and serotonin

C. MAO-A metabolises dopamine; MAO-B metabolises serotonin

D. MAO-A metabolises norepinephrine and dopamine; MAO-B
metabolises serotonin

The mechanism of action of carbamazepine appears to be similar to
that of;
Answer

A. valproate

B. benzodiazepines

C. phenytoin




D. ethosuximide



Indicate the inhaled anaesthetic, which should be avoided in patients with a history of seizure
disorders:
Answer

A. sevoflurane

B. enflurane

C. nitrous oxide

D. desflurane

Inhaled anesthetics and intravenous agents having general anesthetic properties;
Answer

A. increase the duration of opening of nicotine-activated potassium channels

B. directly activate GABA
A
receptors

C. reduce the excitatory glutamatergic neurotransmission

D. facilitate GABA action but have no direct action on GABA
A
receptors

Which of the following antidepressant agent is least likely to be prescribed to patients with
prostatic hypertrophy, glaucoma, coronary and cerebrovacular disease?
Answer

A. fluoxetine

B. paroxetine

C. amitriptyline

D. bupropion


Select the appropriate consideration for phenytoin:
Answer

A. it blocks sodium channels

B. it inhibits GABA-transaminase which catalyses the breakdown of GABA

C. it effects on calcium ion currents, reducing the low-threshold current

D. it binds to an allosteric regulatory site on the GABA-BZ receptor and prolongs the
openings of the chloride ion channels
Which of the following antiseizure drugs binds to an allosteric regulatory site on the GABA-BZ
receptor, increases the duration of the chlorine ion channels openings?
Answer

A. diazepam

B. phenobarbital

C. valproate

D. topiramate

Hypnotic drugs should
Answer

A. reduce anxiety and exert a calming effect

B. induce absence of sensation

C. produce drowsiness, encourage the onset and maintenance of sleep

D. prevent mood swings in patients with bipolar affective disorders
____________ is the anticancer drug of plant origin.
Answer

A. Dactinomycin

B. Vincristine

C. Methotrexate

D. Thioguanine
Levodopa should not be given to patients taking;
Answer

A. carbidopa

B. nonselective beta-adrenergic antagonists

C. bromocriptine

D. monoamine oxydase A inhibitors