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I. Cellular & Molecular Basis for Medical Physiology
1. General Principles & Energy Production in Medical Physiology
2. Overview of Cellular Physiology in Medical Physiology
3. Immunity, Infection & Inflammation
II. Physiology of Nerve & Muscle Cells
4. Excitable Tissue: Nerve
5. Excitable Tissue: Muscle
6. Synaptic & Junctional Transmission
7. Neurotransmitters & Neuromodulators
8. Properties of Sensory Receptors
9. Reflexes
III. Central & Peripheral Neurophysiology
10. Pain & Temperature
11. Somatosensory Pathways
12. Vision
13. Hearing & Equilibrium
14. Smell & Taste
15. Electrical Activity of the Brain, Sleep-Wake States & Circadian Rhythms
16. Control of Posture & Movement
17. The Autonomic Nervous System
18. Hypothalamic Regulation of Hormonal Functions
19. Learning, Memory, Language & Speech
IV. Endocrine & Reproductive Physiology
20. The Thyroid Gland
21. Endocrine Functions of the Pancreas & Regulation of Carbohydrate Metabolism
22. The Adrenal Medulla & Adrenal Cortex
23. Hormonal Control of Calcium & Phosphate Metabolism & the Physiology of Bone
24. The Pituitary Gland
25. The Gonads: Development & Function of the Reproductive System
V. Gastrointestinal Physiology
26. Overview of Gastrointestinal Function & Regulation
27. Digestion, Absorption & Nutritional Principles
28. Gastrointestinal Motility
29. Transport & Metabolic Functions of the Liver
VI. Cardiovascular Physiology
30. Origin of the Heartbeat & the Electrical Activity of the Heart
31. The Heart as a Pump
32. Blood as a Circulatory Fluid & the Dynamics of Blood & Lymph Flow
33. Cardiovascular Regulatory Mechanisms
34. Circulation through Special Regions
VII. Respiratory Physiology
35. Pulmonary Function
36. Gas Transport & pH in the Lung
37. Regulation of Respiration
VIII. Renal Physiology
38. Renal Function & Micturition
39. Regulation of Extracellular Fluid Composition & Volume
40. Acidification of the Urine & Bicarbonate Excretion
From the Authors
We are very pleased to launch the 23rd edition of Ganong's Review of
Medical Physiology. The current authors have attempted to maintain the
highest standards of excellence, accuracy, and pedagogy developed by
Fran Ganong over the 46 years in which he educated countless students
worldwide with this textbook.
At the same time, we have been attuned to the evolving needs of both
students and professors in medical physiology. Thus, in addition to usual
updates on the latest research and developments in areas such as the
cellular basis of physiology and neurophysiology, this edition has added
both outstanding pedagogy and learning aids for students.
We are truly grateful for the many helpful insights, suggestions, and
reviews from around the world that we received from colleagues and
students. We hope you enjoy the new features and the 23rd edition!
This edition is a revision of the original works of Dr. Francis
New 4 Color Illustrations
We have worked with a large team of medical illustrators,
photographers, educators, and students to build an accurate, up-to-
date, and visually appealing new illustration program. Full-color
illustrations and tables are provided throughout, which also include
detailed figure legends that tell a short story or describes the key
point of the illustration.
New Boxed Clinical Cases
Examples of diseases illustrating important physiological principles
are provided in boxed Clinical Cases.
Kim E. Barrett, PhD
Department of Medicine
Dean of Graduate Studies
University of California, San Diego
La Jolla, California
Susan M. Barman, PhD
Department of Pharmacology/Toxicology
Michigan State University
East Lansing, Michigan
Scott Boitano, PhD
Associate Professor, Physiology
Arizona Respiratory Center
Bio5 Collaborative Research Institute
University of Arizona
Tucson, Arizona
Heddwen L. Brooks, PhD
Associate Professor
Department of Physiology
College of Medicine
University of Arizona
Tucson, Arizona