Beruflich Dokumente
Kultur Dokumente
Low High
Low
Scientific
Merit
High
Disclosure of Perfume
“Anyone who cracks the code to know just how molecules of a certain
formation produce a certain smell is liable, not only to advance basic human
knowledge, but also to gain a great deal of money.” (Turin, 2003)
Starting with publications: From a sample of 341 research publications (all the
research articles from the leading life science journal Nature Biotechnology
between 1997 and 1999). Examine which publications are also disclosed in
patents. (Murray and Stern 2007)
How often are patents part of a
patent-paper pairs?
# paired with % paired
# patents
publications patents
Starting with patents: From the full population of human gene patents (US patents
identified using bioinformatics methods that disclose and claim a human gene sequence
or fragment (Jensen and Murray 2005), we examine which patents are also disclosed in
publications. (Huang and Murray 2008 ).
Research Questions
What are the key factors shaping the disclosure of
knowledge in the form of scientific research publications,
patents, or both?
A Theory of Patent-Paper Pairs
Firm/Private Funder
Monopoly profit: P – w
Competitive profit: p – w
Expected profit of the private funder:
P k w P r(entry ( d , id P A T , i l )( P p )
capital cost
m ax w , i , d w b S d ) P k w (p i l b E ( d id P A T i d P A T d ))( P p ) )
w m ax 0, 12 P k (p i l b E ( d id P A T id P A T d ))( P p ) b S d )
*
i
Commercial Patent-Paper
Science Pairs
Open
Secrecy
Science
1 d
Stronger IP Protection
P k ( p i l b E id P A T )( P p )
di
*
2 b E (1 id P A T )( P p )
Increasing l
More likely to take out a patent
If there is publication, negotiate more disclosure
Increasing dPAT
Less likely to take out a patent
If there is a publication, reduces disclosure
d m in 1 l
,1 S ecrecy,
bE d P A T
otherw ise P atent-P aper P airs
Independent Knowledge
Suppose d and dPAT
revealed information i
about distinct knowledge
Commercial Patent-Paper
When d > 1, surplus Science Pairs
maximisation would 1
involve 1 > d
Commercial Patent-Paper
Science Pairs
Open
Secrecy
Science
1 d
P k (1 r )((1 r ) p l b E d P A T
i P k p ( P p )
The Anti-Commons Effect
Fear that patent thickets will deter scientific research
Murray and Stern (2006) found that papers with patents
attached attracted fewer citations
Open
Secrecy Science
1 d
Dynamics
Suppose that scientists and firms live two periods
Overlap with other generations
Patent-Paper Pairs
For d sufficiently high, patent-paper pairs can be an
equilibrium
Presence of patent reduces incentives for publication and vice
versa when r < 1
Increasing r causes more disclosure under patent-paper pairs
Substitutability
i
Commercial Patent-Paper
Science Pairs
Open
Secrecy Science
1 d
Other implications
Look only at symmetric dynamic equilibria
Inter-temporal complementarity
Only worthwhile publishing if expect future scientific work to
be published (so can earn a citation)
Therefore, always exists a commercial science or secrecy
equilibrium.