Metabolic Worksheet Chapter 7 Assignment This Metabolic Worksheet is designed to enhance your understanding of the metabolic pathways that the human body uses to produce energy from the foods that we eat. To complete the worksheet, simply click on each blank and type in your answers. Save the completed worksheet to your computer and submit it to the Chapter 7 Assignment dropbox. Carbohydrate (Glucose) In The Energy Pathways A. GLYCOLYSIS: The breakdown of glucose to pyruvate to energy There are __________ carbons in a glucose molecule. One glucose molecule will produce __________ pyruvate molecules consisting of __________ carbons each. The metabolic pathway that breaks down glucose to pyruvate is known as __________, which occurs in the __________ of the cell and the process is __________, which means without oxygen. Limited energy in the form of __________ is produced during glycolysis. B. THE LACTIC ACID CYCLE: An alternate anaerobic pathway to energy production. If enough oxygen is NOT available, especially during high-intensity exercise, pyruvate converts to __________, which accumulates in the __________ due to limited availability of oxygen and limited clearance of __________. When muscles relax, circulating blood carries lactic acid to the __________, which will then convert it to __________. The conversion of lactic acid to glucose is known as the __________. C. THE TRICARBOXYLIC ACID (TCA) CYCLE: The aerobic pathway to energy production. If enough oxygen is available to the cell, pyruvate converts to a 2-carbon compound known as __________. The CoA part of acetyl CoA is a coenzyme that comes from the B vitamin, __________. If enough oxygen is available to the cell and the cell needs more ATP (energy), acetyl CoA enters the __________ . Other names for the TCA cycle include __________ and __________. The TCA cycle occurs in the __________ of the cell and the process is __________, which means with oxygen. If pyruvate continues through the energy pathway, two of the three carbons in pyruvate combine with coenzyme A to become __________ and the third carbon is expelled as __________. Pyruvate can convert to __________ or __________, but acetyl CoA cannot convert to __________ or __________. Acetyl CoA will proceed through the TCA cycle ONLY if the cell needs more __________. Acetyl CoA that does not enter the TCA cycle will be converted and stored as __________. When acetyl CoA enters the TCA cycle, it converts to several other compounds that produce __________, __________, and provides __________ atoms. The TCA cycle provides __________ atoms for the electron transport chain to produce __________ and __________. D. THE ELECTRON TRANSPORT CHAIN (ETC): The pathway to abundant energy production When acetyl CoA converts to other compounds in the TCA cycle, __________ atoms with their energetic __________ are removed from those compounds. The ETC occurs in the __________ of the cell and the process is __________, which means with oxygen. The transfer of hydrogen to the ETC is made possible because of __________ made from B vitamins. As hydrogen with electrons is passed down the ETC, it releases energy which is captured in __________. At the end of the ETC, very low-energy hydrogen atoms combine with oxygen to form __________. The number of __________ atoms that enter the ETC determines the amount of __________ that will be produced. Fat In The Energy Pathways When dietary fat is needed for energy, the 3-carbon backbone of the triglyceride molecule, known as __________, enters the energy pathway between the compounds __________ and __________. The __________ portions of a triglyceride are taken apart, 2 carbons at a time, through a process known as __________. A fatty acid that contains 20 carbons will yield __________ acetyl CoA molecules. The 2-carbon fragments of a fatty acid can enter the energy pathway only as __________ compounds that can enter the TCA cycle ONLY if the cell needs more __________. Acetyl CoA from triglyceride that is not used for ATP (energy) will be converted and stored as __________. If acetyl CoA from triglyceride enters the TCA cycle, the process continues through the __________ to produce abundant ATP (energy) and water. When a triglyceride molecule breaks down into its basic units, __________ can be used to make glucose, but __________ cannot be used to make glucose. Protein In The Energy Pathways Before protein can enter the energy pathway, enzymes must first __________ (remove nitrogen groups from) the amino acids. The process produces the compound __________ that can then be used to make other amino acids or excreted as __________. An amino acid that can enter the energy pathway between glucose and pyruvate is referred to as a __________ amino acid. An amino acid that can enter the energy pathway as acetyl CoA is referred to as a __________ amino acid. Amino acids that convert to pyruvate can go up to make __________ or go down to make __________. Amino acids that convert to acetyl CoA will enter the TCA cycle ONLY if the cell needs more __________. Amino acids that convert to acetyl CoA cannot be used to make __________. After acetyl CoA enters the TCA cycle, the process continues on through the __________ as described previously for dietary carbohydrate and fat. Just like dietary carbohydrate and fat that is used for energy, dietary protein can also provide __________ atoms that will enter the electron transport chain to produce __________. If ATP (energy) is NOT needed from amino acids, they will be converted and stored as __________. Summary Of Energy Metabolism All dietary carbohydrate, fat, and protein can break down to the common compound __________ that can enter the TCA cycle. Acetyl CoA enters the TCA cycle only if the cell needs more __________. Most of the ATP (energy) made is produced in the part of the energy pathway known as the __________. Abundant ATP (energy) comes from the dietary fat because fat provides more __________. The more hydrogen atoms provided, the more __________ will be produced. If eaten in excess of the bodys needs, all dietary carbohydrate, fat, and protein will be converted and stored as __________.