Name: Kryssel D.

Java Year and Section: BN4A

Ward: EENT
Reference: Chemists Own Pty Ltd
(March 2006). CHEMISTS OWN SORE THROAT LOZENGES- Product Information. Retrieved from
http://www.aspenpharma.com.au/product_info/pi/CO_Sore_Throat_Lozenges_PI_Mar06.pdf

Name of Drug

Dosage,
Frequency &
Route

Mechanism of
Action

Indications

Contraindications

Adverse Reaction

Nursing
Responsibilities

Generic Name:
Benzydamine
Hydrochloride

Brand Name:


Classification:NS
AID with
analgesic, anti-
pyretic and anti-
inflammatory

Category: B2


Dosage: 1
lozenge

Frequency:
Q3h PRN (as
needed)

Route: Oral

Benzydamine
hydrochloride
is a non-steroid
anti-
inflammatory
drug that has
analgesic,
antipyretic
and anti-
inflammatory
actions. It is
used for the
relief of
inflammatory
conditions of
the mouth and
throat.

Treatment of
pain minor
infection and
inflammation
common to
uncomplicate
d sore throat,
oral surgery,
minor mouth
infections
and
dental
procedures.

Known sensitivity to any of the active ingredients or
the excipients.
Known sensitivity to other local anaesthetic agents.
This product is contraindicated in phenylketonurics,
since it contains aspartame, which is
metabolised in the GIT to phenylalanine.

Precautions

Local anaesthetics when used in the mouth or throat
may impair swallowing and increase the risk
of aspiration. Care should be recommended in the use
of hot food or drink after a local anaesthetic,
as the perception of heat may be dulled. The numbing
effect of local anaesthetics can lead to inadvertent
biting of the internal walls of
mouth, the tongue or lip in children and/or the elderly.

Use in pregnancy
Benzydamine is in Category B2: Drugs which have
been taken by only a limited number of
pregnant women and women of childbearing age,
without an increase in the frequency of
malformation or other direct or indirect harmful effects
on the human foetus having been observed.
Studies in animals are inadequate or may be lacking,
but available data shows no evidence of an
increased occurrence of foetal damage.


1. Sensitisation
can occur to
anaesthetics due
to prolonged
use, over use or
inappropriate
use.

2. The most
common side
effects when
large quantities
of isomalt are
ingested are
gastrointestinal
disturbance

3. Excess
consumption of
the lozenges
will result in
excessive
isomalt intake
and can cause
laxative effects.

Overdose:
Excessive ingestion of
these lozenges may
result in serious
problems with
deadening of the
mucosa of the mouth
and larynx. This may
lead to serious
impairment of
swallowing. Overdose
can also lead to major
systemic absorption of
the local anaesthetic,
resulting in cardiac
and central nervous
system symptoms.
These include severe
hypotension, asystole,
bradycardia,
apnoea, seizures,
coma, cardiac arrest,
respiratory arrest and
death.
Store below 30oC in a
dry place. Protect from
moisture.