Ciprofloxacinhydrochloride(Siprohfloxassinhi

drohclorride)isamedicinewhichisusedin
bacterialinfections,cornealulcersandeye
infections.
Yourmedicine
Ciprofloxacinhydrochlorideisusedtotreat
infectionscausedbycertaintypesofbacteria.Itis
alsousedbeforecertaintypesofsurgerytoprevent
infectionswhichmayoccuraftertheseprocedures.
Ciprofloxacinhydrochlorideworksbykillingthe
bacteriathathavecausedtheinfection.
OtherinformationaboutCiprofloxacinhydrochloride:
itisbesttodrinkplentyofwaterwhiletaking
Ciprofloxacinhydrochlorideasthismayhelp
topreventcertaintypesofkidneyproblems
Donotshareyourmedicinewithotherpeople.It
maynotbesuitableforthemandmayharmthem.
Thepharmacylabelonyourmedicinetellsyouhow
muchmedicineyoushouldtake.Italsotellsyou
howoftenyoushouldtakeyourmedicine.Thisis
thedosethatyouandyourprescriberhaveagreed
youshouldtake.Youshouldnotchangethedoseof
yourmedicineunlessyouaretoldtodosobyyour
prescriber.
Ifyoufeelthatthemedicineismakingyouunwellor
youdonotthinkitisworking,thentalktoyour
prescriber.
Whentotakeyourmedicine
Somemedicinesworkbestiftheyaretakenata
specifictimeofday.Gettingthemostbenefitfrom
yourmedicinecanalsobeaffectedbywhatyoueat,
whenyoueatandthetimesatwhichyoutakeother
medicines.
SpecificinformationonwhentotakeCiprofloxacin
hydrochloridecanbefoundinthePatient
InformationLeafletthatcomeswiththismedicineor
onthemedicinelabel.Youcanalsoaskyourdoctor
orpharmacistforinformationaboutwhentotake
yourmedicine.
Howtotakeyourmedicine
Somemedicineshavespecificinstructionsabout
howtotakethem.Thisisbecausetheyworkbetter
whentakencorrectly.Theseinstructionscaninclude
gettingtherightdoseandspecialinstructionsfor
preparingthemedicine.
SpecificinformationonhowtotakeCiprofloxacin
hydrochloridecanbefoundinthePatient
InformationLeafletthatcomeswiththismedicineor
onthemedicinelabel.Alternatively,youcanrequest
informationabouthowtotakeyourmedicinefrom
yourdoctororpharmacist.
Ifyouarehavingproblemstakingthisformof
Ciprofloxacinhydrochloride,youshouldtalktoyour
prescriberorpharmacist.Theymaybeabletogive
youadviceonotherwaystotakeyourmedicineor
otherpreparationsthatareeasierforyoutotake.
Takingtoomuchofyourmedicine
Takingextradosesofsomemedicinescanbe
harmful.Insomecasesevenoneextradosecan
causeyouproblems.Ifyoutakeextradosesofyour
medicine,youmustgetmedicaladviceimmediately.
Youmayneedatesttoassesstheeffectoftaking
extradoses.Thisisbecausetheeffectsoftaking
toomuchmedicineareverycomplexsoitisvery
importantthatyouseekmedicaladvice.
Contactyourprescriber,pharmacist,specialistclinic
orcall111foradvice.
Makesureyoutakeallofyourmedicinecontainers
withyouifyouareadvisedtogotohospital.
Stoppingyourmedicine
Ifyouarenothavinganyproblemswiththis
medicine,donotstoptakingit,evenifyoufeel
better,unlessyouhavecompletedthecourseoryou
areadvisedtostoptakingitbyyourprescriber.
Ifyouareinanydoubt,contactyourprescriber,
pharmacist,specialistclinicorcall111.
Lookingafteryourmedicine
Theinstructionsonhowyoushouldkeepyour
medicineareonthepharmacylabel.Itisagood
ideatokeepyourmedicineintheoriginalcontainer.
Thiswillhelptokeepyourmedicineinthebest
conditionandalsoallowyoutocheckthe
instructions.Donottakethemedicineifthe
packagingappearstohavebeentamperedwithorif
themedicineshowsanysignsofdamage.Make
surethatthemedicineisoutofthesightandreach
ofchildren.
Specificinformationonhowtolookafter
Ciprofloxacinhydrochloridecanbefoundinthe
PatientInformationLeafletthatcomeswiththis
medicineoronthemedicinelabel.Alternatively,you
canrequestinformationabouthowtolookafteryour
medicinefromyourdoctororpharmacist.
Youmustnottakethemedicineaftertheexpirydate
shownonthepackaging.Ifyouhaveanyunused
medicine,returnittoyourpharmacistwhowill
disposeofitsafely.
Whetherthismedicineissuitableforyou
Ciprofloxacinhydrochlorideisnotsuitablefor
everyoneandsomepeopleshouldneveruseit.
Otherpeopleshouldonlyuseitwithspecialcare.It
isimportantthatthepersonprescribingthis
medicineknowsyourfullmedicalhistory.
Yourprescribermayonlyprescribethismedicine
withspecialcareormaynotprescribeitatallifyou:
areallergicorsensitivetoorhavehada
reactiontoanyoftheingredientsinthe
medicine
areallergicorsensitivetomedicinessimilar
toCiprofloxacinhydrochloridesuchas
quinolones
havekidneyproblems
haveorhavehadcentralnervoussystem
problems
haveepilepsy
havecertaintypesofinfections
havemyastheniagravis
havecertaintypesofheartorcirculation
problems
haveglucose6phosphatedehydrogenase
deficiency
havemetabolicproblems
areelderly
haveaslowheartrate
arefemale
havediabetes
Furthermoretheprescribermayonlyprescribethis
medicinewithspecialcareormaynotprescribeitat
allforachildoranadolescent.
Aspartoftheprocessofassessingsuitabilityto
takethismedicineaprescribermayalsoarrange
tests:
todeterminewhetherornotthemedicineis
suitableandwhetheritmustbeprescribed
withextracare
OvertimeitispossiblethatCiprofloxacin
hydrochloridecanbecomeunsuitableforsome
people,ortheymaybecomeunsuitableforit.Ifat
anytimeitappearsthatCiprofloxacinhydrochloride
hasbecomeunsuitable,itisimportantthatthe
prescriberiscontactedimmediately.
Sideeffects
Amedicineisonlymadeavailabletothepublicifthe
clinicaltrialshaveshownthatthebenefitsoftaking
themedicineoutweightherisks.
Onceamedicinehasbeenlicensed,informationon
themedicine'seffects,bothintendedand
unintended,iscontinuouslyrecordedandupdated.
Somesideeffectsmaybeseriouswhileothersmay
onlybeamildinconvenience.
Everyone'sreactiontoamedicineisdifferent.Itis
difficulttopredictwhichsideeffectsyouwillhave
fromtakingaparticularmedicine,orwhetheryou
willhaveanysideeffectsatall.Theimportantthing
istotellyourprescriberorpharmacistifyouare
havingproblemswithyourmedicine.
Common:Morethan1in100peoplewhotake
Ciprofloxacinhydrochloride
arthritisinchildren
diarrhoeaifdiarrhoeaispersistentstop
takingCiprofloxacinhydrochlorideandseek
medicaladvice
nausea
Uncommon:Morethan1in1000peoplewhotake
Ciprofloxacinhydrochloride
abnormallaboratorytestresults
backpain
bloodandbonemarrowproblems
chestpain
feelingdizzy
fever
flatulence
gastrointestinalproblems
headaches
hyperactivity
indigestion
infections
itching
kidneyproblems
lossofappetite
muscle,jointorbonepain
psychomotoragitation
skinrashorrashes
sleepingproblems
stomachpain
tastechanges
urticaria
vomiting
weaknessseekmedicaladviceifyouhave
weakness
Rare:Morethan1in10,000peoplewhotake
Ciprofloxacinhydrochloride
allergicreactions
angioedema
arthritis
bloodintheurine
bloodsugarcontrolchangesindiabetics
breathingdifficulties
confusion
depressionthismayleadtothoughtsof
committingsuicideoranysuicidalbehaviour.
Seekmedicaladviceifyoudevelopfeelings
ofdepression
doublevision
Ciprofloxacinhydrochloride
Ciprofloxacin500mgtablets
Whenusedinbacterialinfections
Providedbywww.medicines.org.uk/guides Page1of3 Lastupdated12Nov13
Copyright2010Datapharm
eyeoreyesightproblems
faintingorbrieflossofconsciousness
fasterheartrate
feelinganxious
feelingsofdisorientation
hallucinations
hearingloss
hypoaesthesia
increasedmuscletone
increasedsweating
inflammationofatendonseekmedical
adviceifatendonispainfulandswollen
liverproblemsseekmedicaladviceifyou
havejaundice,alossofappetite,darkurine,
itchingorstomachtenderness
loweredbloodpressure
musclecramps
oedema
paraesthesiae
photosensitivityskinreactionsyoushould
avoidsunlightorUVlightwhiletakingthis
medicine
pseudomembranouscolitisthismaybefatal
seizuresincludingstatusepilepticusifthis
happens,stoptakingCiprofloxacin
hydrochlorideandseekmedicaladvice
strangedreams
tendonrupture
tinnitus
tremors
vasodilatation
vertigo
Veryrare:Fewerthan1in10,000peoplewhotake
Ciprofloxacinhydrochloride
abnormalgait
anaphylacticreactionorshockseekmedical
adviceifyouhaveananaphylacticreaction
changestosenseofsmell
coordinationproblems
erythemamultiforme
hypersensitivityreactionsseekmedical
adviceifyougetanytypeofhypersensitivity
reaction
intracranialhypertension
migraine
muscleweakness
pancreatitis
petechiae
problemswithcolourvision
psychosisorpsychoticlikebehaviourthis
mayleadtothoughtsofcommittingsuicideor
anysuicidalbehaviour.Ifthishappens,stop
takingCiprofloxacinhydrochlorideandseek
medicaladvice
StevensJohnsonsyndrome
toxicepidermalnecrolysis
vasculitis
worseningofmyastheniagravis
Thefrequencyofthesesideeffectsisunknown
ECGchanges
mayaffecttheresultsforcertaintests
neuropathiesincludingneuropathyofthe
extremitiesseekmedicaladviceifany
symptomsdevelopsuchaspain,burning,
tingling,numbness,weakness,sensory
problemsormuscleweakness
skinproblems
Ifyoufeelunwellorifyouhaveconcernsabouta
sideeffect,youwillneedtoseekadvice.Ifyoufeel
veryill,getmedicalhelpstraightaway.Contactyour
prescriber,pharmacist,nurseorcall111.
Takingothermedicines
Ifyouaretakingmorethanonemedicinetheymay
interactwitheachother.Attimesyourprescriber
maydecidetousemedicinesthatinteract,inother
casesthismaynotbeappropriate.
Thedecisiontousemedicinesthatinteractdepends
onyourspecificcircumstances.Yourprescribermay
decidetousemedicinesthatinteract,ifitisbelieved
thatthebenefitsoftakingthemedicinestogether
outweightherisks.Insuchcases,itmaybe
necessarytoalteryourdoseormonitoryoumore
closely.
Tellyourprescriberthenamesofallthemedicines
thatyouaretakingsothattheycanconsiderall
possibleinteractions.Thisincludesallthemedicines
whichhavebeenprescribedbyyourGP,hospital
doctor,dentist,nurse,healthvisitor,midwifeor
pharmacist.Youmustalsotellyourprescriberabout
medicineswhichyouhaveboughtoverthecounter
withoutprescriptions.
Thefollowingmedicinesmayinteractwith
Ciprofloxacinhydrochloride:
theophylline
tizanidine
ropinirole
phenytoin
sucralfate
didanosine
probenecid
methotrexate
calcium
magnesium
iron
aluminium
sevelamer
caffeine
pentoxifylline
warfarin
clozapine
metoclopramide
omeprazole
ciclosporin
acenocoumarol
phenprocoumon
fluindione
lidocaine
sildenafil
olanzapine
duloxetine
lanthanumcarbonate
Thefollowingtypesofmedicinemayinteractwith
Ciprofloxacinhydrochloride:
mineralsupplements
antacids
polymericphosphatebinders
xanthinederivatives
corticosteroids
medicinesthataremetabolisedbythe
cytochromeP450system
oralanticoagulants
vitaminKantagonists
antiarrhythmics
tricyclicantidepressants
macrolides
antipsychotics
medicinesthatprolongtheQTcinterval
IfyouaretakingCiprofloxacinhydrochlorideand
oneoftheabovemedicinesortypesofmedicines,
makesureyourprescriberknowsaboutit.
Complementarypreparationsandvitamins
Medicinescaninteractwithcomplementary
preparationsandvitamins.
Makesureyoutellyourprescriberthenamesofall
thecomplementarypreparationsandvitaminsthat
youaretakingorareplanningtotake.
Yourprescribercanthendecidewhetheritis
appropriateforyoutotakecombinationsthatare
knowntointeract.
InthecaseofCiprofloxacinhydrochloride:
thismedicinemayinteractwithcaffeineor
mineralsupplementssuchascalcium,
magnesium,aluminiumoriron
IfyouhavebeenprescribedCiprofloxacin
hydrochlorideyoushouldonlytakesomethingon
theabovelistonthespecificadviceofyour
prescriberorpharmacist.
Drivingandoperatingmachinery
Whentakinganymedicineyoushouldbeawarethat
itmightinterferewithyourabilitytodriveoroperate
machinerysafely.
InthecaseofCiprofloxacinhydrochloride:
thismedicinecouldaffectyourabilitytodrive
oroperatemachinery
Youshouldseehowthismedicineaffectsyou
beforeyoujudgewhetheryouaresafetodriveor
operatemachinery.Ifyouareinanydoubtabout
whetheryoushoulddriveoroperatemachinery,talk
toyourprescriber.
Diet
Medicinescaninteractwithcertainfoods.Insome
cases,thismaybeharmfulandyourprescribermay
adviseyoutoavoidcertainfoods.
InthecaseofCiprofloxacinhydrochloride:
thismedicineinteractswithcaffeineand
calcium.Calciumreducesthelevelof
Ciprofloxacinhydrochlorideinyourblood.
YoumustnottakeCiprofloxacin
hydrochloridewithdairyproductsordrinks
whichhaveaddedcalcium
Ifyourdietincludesanyoftheabove,speaktoyour
prescriberorpharmacistforfurtheradvice.
Alcohol
Alcoholcaninteractwithcertainmedicines.
InthecaseofCiprofloxacinhydrochloride:
therearenoknowninteractionsbetween
alcoholandCiprofloxacinhydrochloride
Familyplanningandpregnancy
Mostmedicines,insomeway,canaffectthe
developmentofababyinthewomb.Theeffecton
thebabydiffersbetweenmedicinesandalso
dependsonthestageofpregnancythatyouhave
reachedwhenyoutakethemedicine.
InthecaseofCiprofloxacinhydrochloride:
theuseofthismedicineduringpregnancyis
notrecommended.Youshouldonlytakethis
medicineduringpregnancyifyourdoctor
thinksthatyouneedit
Youneedtodiscussyourspecificcircumstances
withyourdoctortoweighuptheoverallrisksand
benefitsoftakingthismedicine.Youandyourdoctor
canmakeadecisionaboutwhetheryouaregoingto
takethismedicineduringpregnancy.
Ifthedecisionisthatyoushouldnothave
Ciprofloxacinhydrochloride,thenyoushould
discusswhetherthereisanalternativemedicine
thatyoucouldtakeduringpregnancy.
Ciprofloxacinhydrochloride
Ciprofloxacin500mgtablets
Whenusedinbacterialinfections
Providedbywww.medicines.org.uk/guides Page2of3 Lastupdated12Nov13
Copyright2010Datapharm
Breastfeeding
Certainmedicinescanpassintobreastmilkand
mayreachyourbabythroughbreastfeeding.
InthecaseofCiprofloxacinhydrochloride:
breastfeedingisnotrecommendedwhile
takingthismedicine
Beforeyouhaveyourbabyyoushoulddiscuss
breastfeedingwithyourdoctorormidwife.Theywill
helpyoudecidewhatisbestforyouandyourbaby
basedonthebenefitsandrisksassociatedwiththis
medicine.Ifyouwishtobreastfeedyoushould
discusswithyourprescriberwhetherthereareany
othermedicinesyoucouldtakewhichwouldalso
allowyoutobreastfeed.Youshouldnotstopthis
medicinewithouttakingadvicefromyourdoctor.
Ingredientsofyourmedicine
Medicinescontainactiveingredients.Theymayalso
containother,additionalingredientsthathelpensure
thestability,safetyandeffectivenessofthe
medicine.Theyarealsoaddedtoimprovethe
medicine'stasteandappearanceandtomakeit
easiertotake.Somemaybeusedtoprolongthelife
ofthemedicine.
Thismedicinecontainsciprofloxacinhydrochloride.
Weareunabletolistalloftheingredientsforyour
medicinehere.Forafulllist,youshouldrefertothe
patientinformationleafletthatcomeswiththis
medicine.Youshouldcheckthatyouareableto
taketheingredientsofyourmedicine,especiallyif
youhaveanyallergies.Youshouldalsocheck
whetheranyoftheseingredientsareknowntohave
sideeffects.
Ifyouarenotabletotakeanyoftheingredientsin
yourmedicine,talktoyourprescriberorpharmacist
toseeiftheycansuggestanalternativemedicine.If
youhavereactedbadlytoCiprofloxacin
hydrochloridebefore,donottakeCiprofloxacin
hydrochloride.Talktoyourprescriber,pharmacistor
nurseassoonaspossible.
Ciprofloxacinhydrochloride
Ciprofloxacin500mgtablets
Whenusedinbacterialinfections
Providedbywww.medicines.org.uk/guides Page3of3 Lastupdated12Nov13
Copyright2010Datapharm