Yuhong Zhang

276 Grove Street #.8, Newton, MA, 02466, USA

( 617) 953-4904 (cell); yuhzhang2003@yahoo.com

EDUCATION AND ACADEMIC DEGREES

1986-1987, M.Sc.training program in Pharmacology, Anhui Medical University, Hefei, Anhui,

P.R.China ( Pharmacology)

1983, Bachelor of medicine, Xian Medical University, Xian, Shaanxi, P.R.China ( Pharmacy)

March 2009, Clinical Research Professional Development Program, Kriger Research Center

Nov. 2007, certificated, Basic Human Subjects Training, Beth Israel Deaconess Medical Center,
Boston, Ma, USA

Dec. 2007, certificated, Good Clinical Practice, Beth Israel Deaconess Medical Center, Boston,
Ma, USA

2003-2007, certificated annual training on clinical research, human subjects etc, UTMB,
Galveston, TX, USA

Jul. 2004, certificated, bDNA diagnosis test, Oakland, Ca, USA

PROFESSIONAL APPOINTMENTS

• Research associate in Beth Israel Deaconess Medical Center, Jul.2007-now

• Research fellow, Research associate, in University Texas Medical Branch. USA 1999-
July.2007
• Research administrator in Beijing Biotechnology and New Drugs Center,1997-1999
• Lecturer, research fellow of Pharmacology, in Qinghai Medical School 1983 -1997

TECHNICAL SKILLS:

My work experience mainly focuses on molecular biology and in vivo pharmacology area.
Molecular and Cell Biology:

• Real Time PCR

• miRNA
• Isolation of lymphocytes
• RNA,DNA, Protein isolation
• RNase protection assay
• Southern blot
• Northern blot analysis
• Membrane-based cDNA macroarrays
• Cell culture (primary cell culture)
• Stable transfection
• Western blot
• Two-Dimensional Gel Electrophoresis

Immunology:

• Immunohistochemical staining
• Elisa assay

Laboratory management

• Clinical samples collection and shipment

• Serum bank and tissue bank maintenance
• Data analysis, and familiar with bioinformatics
• Order lab supply
• Lab equipments maintenance
• Protocol creating and modification

In Vivo Pharmacology Work:

• Small animal surgery, collection of blood and various tissue types for ex vivo
analysis( primary cell culture, fix tissue for histology work)
• Animal injections, dosing by using various routes of administration (IV, PO, SC, IM, ID,
IP)
• Animal bleeding, assessment (clinical observations, health checks, and disease scoring).
• Establishing tumor models in mice and rat by injecting tumor cells or performing
subcutaneous (SC) implant for cancer pharmacology study
• Acute, chronic toxicity experiments

Computer Skills

• Microsoft Office XP (Word, Excel, PowerPoint, Access).

PUBLICATIONS AND PRESENTATIONS:

• Yuhong Zhang et al: Ribavirin Treatment Up-regulates Antiviral Gene _Expression via the
Interferon-Stimulated Response Element in Respiratory Syncytial Virus-Infected Epithelial
Cells. Journal of Virology, May.2003, p.5933-5947
• Yuhong Zhang et al: _Expression of Respiratory Syncytial Virus-Induced Chemokine
Gene Networks in Lower Airway Epithelial Cells Revealed by cDNA Microarrays. Journal
of Virology, Oct.2001, p.9044-9058
• D. Lau, Y. Zhang, J. Chen, S. Holder, M. bhasin, T. Libermann, M. Gale, Jr. Differential
Hepatic MicroRNA Expression Profiles Associated With Interferon Alpha Treatment
Response In Patients With Chronic Hepatitis C. Abstract for the European Association
for the Study of the Liver (EASL) Dec. 2009
• Daryl Lau, Mala Sinha, Bruce Luxon, Yuhong Zhang et al: Interferon-induced Gene
Expression in Liver and Peripheral Blood Mononuclear cells(PBMCs) in HCV Genotype 1
patients. Abstract on 15th International Symposium on Hepatitis C Virus & Related
Viruses 2008.
• Brasier AR, Spratt H, Wu Z, Boldogh I, Zhang Y, et al: Nuclear Heat Shock Response
and Novel Nuclear Domain 10 Reorganization in Respiratory Syncytial Virus-infected
A549 Cells Identified by High-Resolution Two-Dimensional Gel Electrophoresis. Journal
of Virology, Nov.2004, p.11461-11476
• Tian B, Zhang Y, Luxon BA, Garofalo RP, Casola A, Sinha M, Brasier AR. Identification
of NF-kappaB-dependent gene networks in respiratory syncytial virus-infected cells.
Jounal of Virology, Jul.2002, p.824-836
• Yuhong Zhang et al: Measurement of hair vanadium in patients with heart, haptic and
renal dysfunction. Journal of Qinghai Medical College 1998,19(1):1
• Yuhong Zhang: Anti-HIV effect of Fluoroquinolones. Journal of Chinese Northwest
Pharmcology 1997,2:88
• Yuhong Zhang et al: Measurement of hair vanadium in acute leukemia. Journal of
Qinghai Medical College 1996,1:18
• Yuhong Zhang et al: Development and application of ion pump inhibitor. Journal of
Qinghai Medicine 1994,5:88
• Yuhong Zhang: ACEI is benefit for patients with acute heart infarction. Journal of Qinghai
Medical College 1993,14(2):122

Textbook:

• Advance pharmacology course, 3rd,Shaanxi people's educational press, 1995

• Apply clinic pharmcology,1st, Gansu culture press, 1996

Reference:

Available upon request